iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-053444

Ensembl Protein ID

ENSLAFP00000001055.4

UniProt Accession

G3SN92; G3SN92_LOXAF

Protein Name

Uncharacterized protein

Gene Name

CD2AP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000001252.4	ENSLAFT00000001251.4	ENSLAFP00000001055.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.80e-66	220.3	270	329

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +ke++++l+ ye++n+deL++k+G+++++i+k++ ++gW++g  el+gk+G+fP+nF ++++
   Q: 270  AKEYCRTLFGYEGTNEDELSFKEGEIIHLISKDTGEAGWWRG--ELNGKEGVFPDNFAVQIS 329
           689***************************************..9*************9986 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

LVDYIVEYDY DAVHDDELTI RVGEIIRNVK KLQEEGWLEG ELNGRRGMFP DNFVKEIKRE 60
TESRDDNLPI KRERHGNVAS LVQRISTYGL PAGGIQPHPQ TKNIKKKTKK RQCKVLFEYT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTAGTTGACT ATATCGTGGA GTATGACTAT GATGCTGTAC ATGATGATGA ATTAACTATT 60
CGAGTTGGAG AAATCATTAG GAACGTGAAA AAGCTACAGG AGGAGGGATG GCTAGAAGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028445--CD2AP
IPR001452--SH3_domain

PROSITE

PS50002--SH3

Pfam

PF00018--SH3_1
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005911--C:cell-cell junction
GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0031941--C:filamentous actin
GO:0005886--C:plasma membrane
GO:0001726--C:ruffle
GO:0032911--P:negative regulation of transforming growth factor beta1 production
GO:1900182--P:positive regulation of protein localization to nucleus
GO:2000249--P:regulation of actin cytoskeleton reorganization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001574	Ailuropoda melanoleuca	87.09	0.00e+00	939.00
IUUC-Apl-003573	Anas platyrhynchos	64.94	4.00e-162	565.00
IUUC-Aca-005118	Anolis carolinensis	63.38	3.00e-163	568.00
IUUC-Ame-010657	Astyanax mexicanus	53.26	1.00e-90	327.00
IUUC-Bta-012577	Bos taurus	82.33	0.00e+00	826.00
IUUC-Cja-020010	Callithrix jacchus	86.27	0.00e+00	912.00
IUUC-Cfa-020040	Canis familiaris	90.16	0.00e+00	944.00
IUUC-Cpo-021906	Cavia porcellus	79.97	0.00e+00	782.00
IUUC-Csa-024008	Chlorocebus sabaeus	87.68	0.00e+00	882.00
IUUC-Cho-024359	Choloepus hoffmanni	76.19	1.00e-65	244.00
IUUC-Csv-026228	Ciona savignyi	40.37	1.00e-24	105.00
IUUC-Dre-027661	Danio rerio	55.65	5.00e-93	335.00
IUUC-Dno-029568	Dasypus novemcinctus	89.24	0.00e+00	881.00
IUUC-Dor-030286	Dipodomys ordii	74.06	0.00e+00	692.00
IUUC-Ete-032576	Echinops telfairi	69.38	0.00e+00	635.00
IUUC-Eca-033438	Equus caballus	87.99	0.00e+00	948.00
IUUC-Eeu-034588	Erinaceus europaeus	71.02	8.00e-144	503.00
IUUC-Fca-036597	Felis catus	88.65	0.00e+00	961.00
IUUC-Fal-037305	Ficedula albicollis	63.43	5.00e-165	574.00
IUUC-Gmo-039516	Gadus morhua	46.04	8.00e-66	244.00
IUUC-Gga-040979	Gallus gallus	65.90	1.00e-177	616.00
IUUC-Gac-041945	Gasterosteus aculeatus	52.57	1.00e-79	290.00
IUUC-Ggo-044488	Gorilla gorilla	87.99	0.00e+00	916.00
IUUC-Hsa-045909	Homo sapiens	87.83	0.00e+00	915.00
IUUC-Itr-049058	Ictidomys tridecemlineatus	91.52	7.00e-127	446.00
IUUC-Lch-049481	Latimeria chalumnae	54.88	3.00e-152	531.00
IUUC-Loc-052715	Lepisosteus oculatus	52.71	4.00e-145	508.00
IUUC-Mcc-054844	Macaca mulatta	87.83	0.00e+00	883.00
IUUC-Meu-056491	Macropus eugenii	64.17	7.00e-178	617.00
IUUC-Mga-060154	Meleagris gallopavo	65.79	2.00e-176	612.00
IUUC-Mmr-061099	Microcebus murinus	85.80	0.00e+00	881.00
IUUC-Mdo-062769	Monodelphis domestica	70.72	0.00e+00	757.00
IUUC-Mmu-063136	Mus musculus	83.31	0.00e+00	785.00
IUUC-Mpu-066509	Mustela putorius furo	87.54	0.00e+00	867.00
IUUC-Mlu-067174	Myotis lucifugus	82.74	0.00e+00	856.00
IUUC-Nle-070147	Nomascus leucogenys	87.68	0.00e+00	915.00
IUUC-Opr-070752	Ochotona princeps	78.76	8.00e-160	556.00
IUUC-Ont-071810	Oreochromis niloticus	54.55	3.00e-101	362.00
IUUC-Oan-072731	Ornithorhynchus anatinus	73.39	1.00e-168	586.00
IUUC-Ocu-074331	Oryctolagus cuniculus	87.11	0.00e+00	882.00
IUUC-Ola-086404	Oryzias latipes	55.00	1.00e-84	307.00
IUUC-Oga-088200	Otolemur garnettii	87.68	0.00e+00	976.00
IUUC-Oar-090423	Ovis aries	80.47	0.00e+00	791.00
IUUC-Ptr-091230	Pan troglodytes	88.14	0.00e+00	920.00
IUUC-Pan-091823	Papio anubis	87.83	0.00e+00	881.00
IUUC-Psi-093127	Pelodiscus sinensis	63.47	1.00e-163	570.00
IUUC-Pfo-096539	Poecilia formosa	49.56	4.00e-87	315.00
IUUC-Pab-097666	Pongo abelii	88.30	0.00e+00	904.00
IUUC-Pca-100812	Procavia capensis	88.98	6.00e-143	501.00
IUUC-Pva-102260	Pteropus vampyrus	80.55	0.00e+00	745.00
IUUC-Rno-106038	Rattus norvegicus	81.75	0.00e+00	804.00
IUUC-Sha-106975	Sarcophilus harrisii	71.36	0.00e+00	730.00
IUUC-Sar-113386	Sorex araneus	84.96	8.00e-107	380.00
IUUC-Ssc-115569	Sus scrofa	91.50	7.00e-114	402.00
IUUC-Tgu-117104	Taeniopygia guttata	65.19	3.00e-180	624.00
IUUC-Tru-117649	Takifugu rubripes	52.31	8.00e-95	341.00
IUUC-Tsy-119258	Tarsius syrichta	79.38	0.00e+00	801.00
IUUC-Tni-120755	Tetraodon nigroviridis	45.89	4.00e-123	435.00
IUUC-Tbe-127842	Tupaia belangeri	65.84	2.00e-112	399.00
IUUC-Ttr-129205	Tursiops truncatus	86.52	0.00e+00	784.00
IUUC-Vpa-130434	Vicugna pacos	82.25	0.00e+00	726.00
IUUC-Xtr-132766	Xenopus tropicalis	57.56	3.00e-86	312.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence