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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063424
UUCD1 version UUC-MuM-00225
Ensembl Protein ID ENSMUSP00000104890.2
UniProt Accession F8VQ72; F8VQ72_MOUSE
Genbank Protein ID ENSMUSP00000104890
Protein Name Mitogen-activated protein kinase kinase kinase 1
Genbank Nucleotide ID AC118704
Gene Name Map3k1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000021754.17 ENSMUST00000109267.8 ENSMUSP00000104890.2
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RepTarRAID2
Protein-protein Interaction
HINT
Post-translational Modifications (PTMs)
PHOSIDABioGRID
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 2.00e-16 61.0 435 489
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 1    ekvClvCgeggedekslveCek.CrewfHpaClklsveeelpnsekwiCpkCrsk 54
           e++C++C  g+ de+sl++Ce+ Cr+++H++C+++++ee+++n+e++iCp Crsk
   Q: 435  EQMCPICLLGMLDEESLTVCEDgCRNKLHHHCMSIWAEECRRNREPLICPLCRSK 489
           69**************************************************985 PP
   
Organism Mus musculus
Protein Sequence
(Fasta)
MAAAAGDRAS SSGFPGAAAA SPEAGGGGGG GGALQGSGAP AAGAAGLLRE PGSAGRERAD 60
WRRRQLRKVR SVELDQLPEQ PLFLAAASPP CPSTSPSPEP ADAAAGASRF QPAAGPPPPG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063424|E3,PHD|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGCGAATGTA GCCCGCGAGA GAAAATGGCG GCGGCGGCGG GCGATCGCGC CTCGTCGTCG 60
GGATTCCCGG GCGCCGCGGC GGCGAGTCCC GAGGCGGGCG GCGGCGGCGG AGGAGGAGGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063424|E3,PHD|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR016024--ARM-type_fold
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR007527--Znf_SWIM
PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50089--ZF_RING_2
PS50966--ZF_SWIM
Pfam

PF00069--Pkinase
PF04434--SWIM
SMART

SM00220--S_TKc
Gene Ontology

GO:0005524--F:ATP binding
GO:0004672--F:protein kinase activity
GO:0008270--F:zinc ion binding
GO:0071260--P:cellular response to mechanical stimulus
KEGG mmu:26401
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002233 Ailuropoda melanoleuca 90.94 0.00e+00 2207.00
IUUC-Apl-003550 Anas platyrhynchos 69.80 9.00e-60 223.00
IUUC-Aca-004258 Anolis carolinensis 81.87 0.00e+00 1920.00
IUUC-Ame-011412 Astyanax mexicanus 70.60 0.00e+00 1686.00
IUUC-Bta-013046 Bos taurus 88.80 0.00e+00 2221.00
IUUC-Cja-019060 Callithrix jacchus 91.69 0.00e+00 2178.00
IUUC-Cfa-020837 Canis familiaris 90.28 0.00e+00 2169.00
IUUC-Cpo-022141 Cavia porcellus 90.51 0.00e+00 2219.00
IUUC-Csa-023082 Chlorocebus sabaeus 91.32 0.00e+00 2197.00
IUUC-Cho-024597 Choloepus hoffmanni 86.21 1.00e-166 581.00
IUUC-Cin-025107 Ciona intestinalis 57.07 2.00e-59 221.00
IUUC-Csv-026034 Ciona savignyi 45.64 2.00e-129 457.00
IUUC-Dre-028821 Danio rerio 70.55 0.00e+00 1726.00
IUUC-Dno-029178 Dasypus novemcinctus 89.37 0.00e+00 2248.00
IUUC-Dor-030534 Dipodomys ordii 89.96 0.00e+00 2275.00
IUUC-Ete-032843 Echinops telfairi 89.12 0.00e+00 2054.00
IUUC-Eca-033650 Equus caballus 89.61 0.00e+00 2133.00
IUUC-Eeu-034569 Erinaceus europaeus 87.77 7.00e-95 342.00
IUUC-Fca-035802 Felis catus 88.73 0.00e+00 2239.00
IUUC-Fal-037259 Ficedula albicollis 82.11 0.00e+00 1962.00
IUUC-Gga-040810 Gallus gallus 82.02 0.00e+00 1994.00
IUUC-Ggo-045102 Gorilla gorilla 90.90 0.00e+00 2204.00
IUUC-Hsa-045671 Homo sapiens 88.42 0.00e+00 2219.00
IUUC-Itr-048840 Ictidomys tridecemlineatus 91.35 0.00e+00 1758.00
IUUC-Lch-050377 Latimeria chalumnae 70.79 0.00e+00 1674.00
IUUC-Loc-052431 Lepisosteus oculatus 73.11 0.00e+00 1788.00
IUUC-Laf-053894 Loxodonta africana 87.37 0.00e+00 2207.00
IUUC-Mcc-055263 Macaca mulatta 91.67 0.00e+00 2202.00
IUUC-Meu-056425 Macropus eugenii 72.03 0.00e+00 664.00
IUUC-Mga-060098 Meleagris gallopavo 68.68 0.00e+00 1221.00
IUUC-Mmr-061686 Microcebus murinus 83.14 0.00e+00 2096.00
IUUC-Mdo-062008 Monodelphis domestica 80.86 0.00e+00 2007.00
IUUC-Mpu-066599 Mustela putorius furo 90.11 0.00e+00 2194.00
IUUC-Mlu-067383 Myotis lucifugus 82.85 0.00e+00 1932.00
IUUC-Nle-069023 Nomascus leucogenys 91.38 0.00e+00 2169.00
IUUC-Opr-070921 Ochotona princeps 81.34 0.00e+00 1544.00
IUUC-Oan-073487 Ornithorhynchus anatinus 82.21 0.00e+00 2021.00
IUUC-Ocu-074697 Oryctolagus cuniculus 90.57 0.00e+00 2199.00
IUUC-Oga-088673 Otolemur garnettii 90.24 0.00e+00 2187.00
IUUC-Oar-089502 Ovis aries 91.01 0.00e+00 2193.00
IUUC-Ptr-090480 Pan troglodytes 88.46 0.00e+00 2217.00
IUUC-Pan-092294 Papio anubis 88.86 0.00e+00 2227.00
IUUC-Psi-093454 Pelodiscus sinensis 98.38 6.00e-139 486.00
IUUC-Pma-094215 Petromyzon marinus 63.36 1.00e-169 589.00
IUUC-Pab-097948 Pongo abelii 88.26 0.00e+00 2241.00
IUUC-Pca-101118 Procavia capensis 85.54 0.00e+00 1877.00
IUUC-Pva-102761 Pteropus vampyrus 86.04 0.00e+00 2132.00
IUUC-Rno-105787 Rattus norvegicus 93.46 0.00e+00 2364.00
IUUC-Sha-106698 Sarcophilus harrisii 84.79 0.00e+00 2031.00
IUUC-Sar-113569 Sorex araneus 88.88 0.00e+00 1469.00
IUUC-Ssc-115862 Sus scrofa 90.10 0.00e+00 2282.00
IUUC-Tgu-117455 Taeniopygia guttata 81.51 0.00e+00 1967.00
IUUC-Tsy-119272 Tarsius syrichta 89.23 0.00e+00 2080.00
IUUC-Tbe-127403 Tupaia belangeri 83.90 0.00e+00 1284.00
IUUC-Ttr-128576 Tursiops truncatus 89.50 0.00e+00 2102.00
IUUC-Vpa-130139 Vicugna pacos 91.24 0.00e+00 2228.00
Created Date 25-Jun-2017

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