iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-092141

Ensembl Protein ID

ENSPANP00000019174.1

UniProt Accession

A0A096P1E9; A0A096P1E9_PAPAN

Genbank Protein ID

ENSPANP00000019174

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01091888

Gene Name

PLAA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000025264.1	ENSPANT00000025995.1	ENSPANP00000019174.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.70e-27	92.3	149	179
UBD/Beta-Prp	3.20e-66	223.6	12	302

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gHt+ v++++  ++ +l+++Gs D+tik+W 
   Q: 149  GHTAAVWAVKIlPEqGLMLTGSADKTIKLWK 179
           8*********99999***************7 PP

UBD/Beta-Prp

   S: 3    ktlkghhksvitcvkf.spdksllatgsrdgtikvwdvttgkl....lrslsgheaevtavkfspdgk.....ilvtgseDrtikvwdl 81
           ++l+gh+ +v   v++  p +  +++ srd+t+++w  ++++     ++++sgh+++v++v+++p+++     +++tg++D++i++++l
   Q: 12   CSLRGHELDVRGLVCCpFPPG-AFVSVSRDRTTRLWAPDSPNRgfteMHCMSGHSNFVSCVCIIPSSDiyphgLIATGGNDHNICIFSL 99
           88999*******999955555.5889999*************999***********************999999*************** PP
   S: 82   stgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgk 170
           +++ ++++lkgh+++v+sls+ +   +l+sGs+d t++vw   +++c+  tl+gh+++v+ v++ p++ l+ +Gs+D+t++lW  k g+
   Q: 100  DSPMPLYILKGHKNTVCSLSSGK-FGTLLSGSWDTTAKVW--LNDKCMM-TLQGHTAAVWAVKILPEQGLMLTGSADKTIKLW--KAGR 182
           **********************9.9***************..9******.*********************************..88** PP
   S: 171  llrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllkt 259
           + rt+ g h+d v+ l++ s+ +e++s+++d +v+ w++ tgec++ + ght+ ++s+ ++pn   +v++++D+s+riW  ++g++ +t
   Q: 183  CERTFAG-HEDCVRGLAILSE-TEFLSCANDASVRRWQI-TGECLEVYYGHTNYIYSISVFPNCRDFVTTAEDRSLRIW--KHGECAQT 266
           *****99.*********9996.8****************.***************************************..9******* PP
   S: 260  lqlhnssvisvavlsfgdnvlvlgsedskvniwklkkn 297
           + l+++s+++++v  +++  +v g++d++++++  +++
   Q: 267  IRLPAQSIWCCCV--LDNGDIVVGASDGIIRVFTESED 302
           *************..9999*************997766 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MTSGATRYRL SCSLRGHELD VRGLVCCPFP PGAFVSVSRD RTTRLWAPDS PNRGFTEMHC 60
MSGHSNFVSC VCIIPSSDIY PHGLIATGGN DHNICIFSLD SPMPLYILKG HKNTVCSLSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACGAGCG GCGCCACCAG GTACCGGCTG AGCTGCTCGC TCCGGGGCCA CGAGCTGGAC 60
GTACGGGGCC TGGTGTGCTG TCCCTTTCCG CCGGGGGCCT TTGTGTCCGT GTCCCGAGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR033510--PLAA/Doa1/Lub1
IPR015155--PLAA_fam_Ub-bd_PFU
IPR013535--PUL_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS51394--PFU
PS51396--PUL
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF09070--PFU
PF08324--PUL
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0016005--F:phospholipase A2 activator activity
GO:0006954--P:inflammatory response

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000146	Aegilops tauschii	31.18	1.00e-89	323.00
IUUC-Aml-002125	Ailuropoda melanoleuca	95.62	0.00e+00	1595.00
IUUC-Atr-002554	Amborella trichopoda	30.93	4.00e-96	345.00
IUUC-Apl-004094	Anas platyrhynchos	81.36	0.00e+00	1259.00
IUUC-Aca-004726	Anolis carolinensis	80.08	0.00e+00	1321.00
IUUC-Aly-005961	Arabidopsis lyrata	32.08	1.00e-106	380.00
IUUC-Ath-006639	Arabidopsis thaliana	32.55	1.00e-102	367.00
IUUC-Ago-007772	Ashbya gossypii	28.94	5.00e-79	288.00
IUUC-Acl-008316	Aspergillus clavatus	31.61	3.00e-87	316.00
IUUC-Afl-008532	Aspergillus flavus	32.84	8.00e-90	325.00
IUUC-Afu-008950	Aspergillus fumigatus	32.19	2.00e-89	323.00
IUUC-Ani-009186	Aspergillus nidulans	33.46	1.00e-92	334.00
IUUC-Ang-009575	Aspergillus niger	31.24	2.00e-85	310.00
IUUC-Aor-010086	Aspergillus oryzae	32.84	8.00e-90	325.00
IUUC-Ate-010541	Aspergillus terreus	30.48	4.00e-84	306.00
IUUC-Ame-011633	Astyanax mexicanus	66.92	0.00e+00	1108.00
IUUC-Bgr-012292	Blumeria graminis	30.12	7.00e-92	331.00
IUUC-Bta-013218	Bos taurus	93.37	0.00e+00	1566.00
IUUC-Bci-013876	Botrytis cinerea	39.60	5.00e-90	325.00
IUUC-Bdi-014810	Brachypodium distachyon	33.08	9.00e-102	364.00
IUUC-Bol-016006	Brassica oleracea	32.81	7.00e-107	381.00
IUUC-Bra-017593	Brassica rapa	33.46	1.00e-107	384.00
IUUC-Cel-018703	Caenorhabditis elegans	27.53	3.00e-70	260.00
IUUC-Cja-019270	Callithrix jacchus	97.24	0.00e+00	1612.00
IUUC-Cfa-021262	Canis familiaris	95.38	0.00e+00	1587.00
IUUC-Cpo-021449	Cavia porcellus	88.26	0.00e+00	1436.00
IUUC-Csa-024140	Chlorocebus sabaeus	99.50	0.00e+00	1644.00
IUUC-Cho-024923	Choloepus hoffmanni	93.75	0.00e+00	764.00
IUUC-Cin-025373	Ciona intestinalis	40.39	1.00e-175	610.00
IUUC-Csv-026324	Ciona savignyi	42.20	0.00e+00	651.00
IUUC-Cgl-026711	Colletotrichum gloeosporioides	30.84	2.00e-84	306.00
IUUC-Cne-026998	Cryptococcus neoformans	32.39	2.00e-85	310.00
IUUC-Cme-027154	Cyanidioschyzon merolae	30.22	6.00e-57	215.00
IUUC-Dre-028674	Danio rerio	64.96	0.00e+00	1089.00
IUUC-Dno-028966	Dasypus novemcinctus	94.11	0.00e+00	1569.00
IUUC-Dor-030343	Dipodomys ordii	87.80	0.00e+00	903.00
IUUC-Dse-031385	Dothistroma septosporum	31.34	7.00e-83	301.00
IUUC-Dme-032044	Drosophila melanogaster	36.72	1.00e-125	444.00
IUUC-Ete-032506	Echinops telfairi	83.46	0.00e+00	826.00
IUUC-Eca-033547	Equus caballus	94.49	0.00e+00	1569.00
IUUC-Eeu-034462	Erinaceus europaeus	92.62	7.00e-143	501.00
IUUC-Fca-035893	Felis catus	94.37	0.00e+00	1566.00
IUUC-Fal-037235	Ficedula albicollis	81.85	0.00e+00	1365.00
IUUC-Fox-037836	Fusarium oxysporum	32.25	6.00e-96	345.00
IUUC-Fso-038251	Fusarium solani	31.21	1.00e-93	337.00
IUUC-Gmo-038648	Gadus morhua	66.08	0.00e+00	956.00
IUUC-Ggr-039867	Gaeumannomyces graminis	30.81	5.00e-84	305.00
IUUC-Gga-040989	Gallus gallus	79.60	0.00e+00	1315.00
IUUC-Gac-041344	Gasterosteus aculeatus	66.83	0.00e+00	1065.00
IUUC-Gma-043067	Glycine max	31.84	1.00e-104	374.00
IUUC-Ggo-045009	Gorilla gorilla	98.36	0.00e+00	1259.00
IUUC-Hsa-046807	Homo sapiens	98.37	0.00e+00	1628.00
IUUC-Itr-048636	Ictidomys tridecemlineatus	95.12	0.00e+00	1583.00
IUUC-Kpa-049134	Komagataella pastoris	43.04	6.00e-89	322.00
IUUC-Lch-049597	Latimeria chalumnae	72.78	0.00e+00	737.00
IUUC-Lpe-050821	Leersia perrieri	31.40	8.00e-98	351.00
IUUC-Loc-051849	Lepisosteus oculatus	72.42	0.00e+00	1195.00
IUUC-Lma-053297	Leptosphaeria maculans	33.54	2.00e-103	369.00
IUUC-Laf-053495	Loxodonta africana	93.99	0.00e+00	1571.00
IUUC-Meu-055983	Macropus eugenii	80.95	0.00e+00	645.00
IUUC-Mor-057006	Magnaporthe oryzae	36.17	4.00e-73	269.00
IUUC-Mpo-057465	Magnaporthe poae	35.68	4.00e-73	269.00
IUUC-Mtr-058374	Medicago truncatula	32.59	1.00e-112	400.00
IUUC-Mla-058895	Melampsora laricipopulina	36.46	4.00e-78	285.00
IUUC-Mvi-060297	Microbotryum violaceum	35.12	2.00e-107	383.00
IUUC-Mmr-060810	Microcebus murinus	90.02	0.00e+00	1466.00
IUUC-Mdo-062671	Monodelphis domestica	87.48	0.00e+00	1437.00
IUUC-Mmu-063536	Mus musculus	93.61	0.00e+00	1530.00
IUUC-Mac-064902	Musa acuminata	32.01	5.00e-100	358.00
IUUC-Mpu-066085	Mustela putorius furo	95.24	0.00e+00	1582.00
IUUC-Mlu-067907	Myotis lucifugus	91.95	0.00e+00	994.00
IUUC-Nfi-068457	Neosartorya fischeri	31.73	2.00e-73	270.00
IUUC-Ncr-068622	Neurospora crassa	30.39	4.00e-97	349.00
IUUC-Nle-069049	Nomascus leucogenys	97.49	0.00e+00	1602.00
IUUC-Opr-071013	Ochotona princeps	93.09	6.00e-106	378.00
IUUC-Ont-071339	Oreochromis niloticus	69.97	0.00e+00	1151.00
IUUC-Oan-073353	Ornithorhynchus anatinus	83.40	1.00e-112	398.00
IUUC-Ocu-074625	Oryctolagus cuniculus	95.24	0.00e+00	1585.00
IUUC-Oba-075226	Oryza barthii	29.29	7.00e-84	305.00
IUUC-Obr-076875	Oryza brachyantha	33.17	1.00e-108	387.00
IUUC-Ogl-077057	Oryza glaberrima	32.29	7.00e-108	384.00
IUUC-Ogu-078156	Oryza glumaepatula	32.17	2.00e-107	383.00
IUUC-Oin-079373	Oryza indica	31.92	3.00e-106	379.00
IUUC-Olo-080849	Oryza longistaminata	29.56	3.00e-73	269.00
IUUC-Ome-081654	Oryza meridionalis	28.66	4.00e-83	302.00
IUUC-Oni-082221	Oryza nivara	29.16	1.00e-85	310.00
IUUC-Opu-084103	Oryza punctata	29.20	2.00e-85	310.00
IUUC-Oru-084751	Oryza rufipogon	28.43	4.00e-82	299.00
IUUC-Osa-085584	Oryza sativa	32.04	4.00e-106	379.00
IUUC-Ola-086974	Oryzias latipes	68.72	0.00e+00	1152.00
IUUC-Oga-088052	Otolemur garnettii	90.61	0.00e+00	1485.00
IUUC-Oar-089509	Ovis aries	93.28	0.00e+00	1564.00
IUUC-Ptr-090911	Pan troglodytes	98.50	0.00e+00	1630.00
IUUC-Psi-093543	Pelodiscus sinensis	81.94	0.00e+00	1278.00
IUUC-Pno-094952	Phaeosphaeria nodorum	32.47	2.00e-95	343.00
IUUC-Ppa-095881	Physcomitrella patens	32.51	2.00e-108	386.00
IUUC-Pfo-096739	Poecilia formosa	68.17	0.00e+00	1138.00
IUUC-Pab-098641	Pongo abelii	98.50	0.00e+00	1631.00
IUUC-Pop-099621	Populus trichocarpa	31.27	5.00e-102	365.00
IUUC-Pca-100599	Procavia capensis	84.91	0.00e+00	1301.00
IUUC-Ppe-101874	Prunus persica	32.46	2.00e-109	390.00
IUUC-Pva-103009	Pteropus vampyrus	91.08	0.00e+00	1272.00
IUUC-Pgr-103260	Puccinia graminis	32.65	1.00e-92	334.00
IUUC-Ptt-103711	Puccinia triticina	31.65	2.00e-89	323.00
IUUC-Pte-104337	Pyrenophora teres	32.56	2.00e-92	333.00
IUUC-Pyt-104475	Pyrenophora triticirepentis	32.95	8.00e-95	341.00
IUUC-Rno-105273	Rattus norvegicus	93.98	0.00e+00	1569.00
IUUC-Sce-106351	Saccharomyces cerevisiae	39.87	1.00e-80	294.00
IUUC-Sha-106758	Sarcophilus harrisii	87.02	0.00e+00	1441.00
IUUC-Sja-107687	Schizosaccharomyces japonicus	39.22	2.00e-95	343.00
IUUC-Spo-108093	Schizosaccharomyces pombe	41.32	9.00e-98	351.00
IUUC-Ssl-108623	Sclerotinia sclerotiorum	40.16	2.00e-91	330.00
IUUC-Smo-109368	Selaginella moellendorffii	31.03	5.00e-96	345.00
IUUC-Sit-109699	Setaria italica	33.63	3.00e-108	385.00
IUUC-Sly-111063	Solanum lycopersicum	32.47	9.00e-104	371.00
IUUC-Sar-113199	Sorex araneus	95.74	0.00e+00	820.00
IUUC-Sbi-114745	Sorghum bicolor	32.76	5.00e-100	358.00
IUUC-Sre-115080	Sporisorium reilianum	33.05	1.00e-104	374.00
IUUC-Ssc-115666	Sus scrofa	93.51	0.00e+00	1565.00
IUUC-Tgu-116877	Taeniopygia guttata	80.98	0.00e+00	1354.00
IUUC-Tru-117580	Takifugu rubripes	67.42	0.00e+00	1127.00
IUUC-Tsy-118946	Tarsius syrichta	96.12	0.00e+00	1471.00
IUUC-Tni-119755	Tetraodon nigroviridis	64.65	0.00e+00	1053.00
IUUC-Tca-120977	Theobroma cacao	31.00	6.00e-101	362.00
IUUC-Tre-122217	Trichoderma reesei	31.99	1.00e-96	347.00
IUUC-Tvi-122671	Trichoderma virens	31.03	4.00e-93	335.00
IUUC-Tae-125581	Triticum aestivum	33.08	5.00e-105	375.00
IUUC-Tur-126404	Triticum urartu	24.30	8.00e-22	99.00
IUUC-Tme-126971	Tuber melanosporum	35.13	7.00e-114	404.00
IUUC-Tbe-127858	Tupaia belangeri	77.46	0.00e+00	656.00
IUUC-Ttr-128173	Tursiops truncatus	91.61	0.00e+00	1510.00
IUUC-Uma-129322	Ustilago maydis	33.33	3.00e-105	376.00
IUUC-Vda-129682	Verticillium dahliae	31.44	3.00e-90	326.00
IUUC-Vpa-130607	Vicugna pacos	91.59	0.00e+00	1402.00
IUUC-Vvi-131153	Vitis vinifera	32.60	8.00e-111	394.00
IUUC-Xtr-132208	Xenopus tropicalis	75.03	0.00e+00	1239.00
IUUC-Xma-133098	Xiphophorus maculatus	68.96	0.00e+00	1127.00
IUUC-Yli-134646	Yarrowia lipolytica	39.63	1.00e-96	347.00
IUUC-Zma-135920	Zea mays	30.96	1.00e-91	330.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence