iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-069336

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01088872

Gene Name

KEAP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000012241.2	ENSNLET00000015610.2	ENSNLEP00000014865.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	3.90e-17	62.3	77	148
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	3.10e-09	36.0	181	211

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvv....g.geeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           +Dv+l+v    +   +f ahk+vLa+sS+vF+a+f+++l+e+   + v i+++ p+v++ l++F Yt ++++ 
   Q: 77   CDVTLQVkyqdApAAQFMAHKVVLASSSPVFKAMFTNGLREQG-MEVVSIEGIHPKVMERLIEFAYTASISMG 148
           8******77552699**************************98.***********************998875 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++N++gi  fA++ +c +L+++a+++i  hF
   Q: 181  PSNAIGIANFAEQIGCVELHQRAREYIYMHF 211
           89****************************9 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MQPDPRPSGA GACSRFLPLQ SQCPEGAGDA VMYASTECKA EVTPSQHGNR TFSYTLEDHT 60
KQAFGIMNEL RLSQQLCDVT LQVKYQDAPA AQFMAHKVVL ASSSPVFKAM FTNGLREQGM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCAGCCAG ATCCCAGGCC TAGCGGGGCT GGGGCCTGCA GCCGATTCCT GCCCCTGCAG 60
TCACAGTGCC CTGAGGGGGC AGGGGACGCG GTGATGTACG CCTCCACTGA GTGCAAGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR030563--KEAP1
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005815--C:microtubule organizing center
GO:0030496--C:midbody
GO:0005654--C:nucleoplasm
GO:0010499--P:proteasomal ubiquitin-independent protein catabolic process
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001377	Ailuropoda melanoleuca	57.03	1.00e-148	520.00
IUUC-Aca-005389	Anolis carolinensis	52.26	2.00e-123	436.00
IUUC-Ame-010749	Astyanax mexicanus	49.39	1.00e-113	403.00
IUUC-Bta-013505	Bos taurus	50.95	1.00e-155	543.00
IUUC-Cja-018823	Callithrix jacchus	51.75	2.00e-161	562.00
IUUC-Cfa-021202	Canis familiaris	50.95	2.00e-155	542.00
IUUC-Cpo-021830	Cavia porcellus	83.49	9.00e-107	380.00
IUUC-Csa-023728	Chlorocebus sabaeus	52.06	1.00e-161	563.00
IUUC-Dre-027388	Danio rerio	48.55	6.00e-110	391.00
IUUC-Dno-029066	Dasypus novemcinctus	52.32	1.00e-145	509.00
IUUC-Dor-030674	Dipodomys ordii	81.65	4.00e-105	374.00
IUUC-Ete-032255	Echinops telfairi	93.96	3.00e-98	352.00
IUUC-Eca-034381	Equus caballus	50.24	2.00e-147	516.00
IUUC-Eeu-034791	Erinaceus europaeus	51.94	4.00e-111	395.00
IUUC-Fca-036067	Felis catus	51.90	2.00e-159	555.00
IUUC-Gmo-039691	Gadus morhua	49.90	9.00e-113	400.00
IUUC-Gga-040266	Gallus gallus	45.05	7.00e-109	387.00
IUUC-Gac-041866	Gasterosteus aculeatus	48.76	8.00e-111	394.00
IUUC-Ggo-044719	Gorilla gorilla	52.38	6.00e-162	563.00
IUUC-Hsa-046255	Homo sapiens	52.38	6.00e-162	563.00
IUUC-Itr-048457	Ictidomys tridecemlineatus	56.84	3.00e-149	521.00
IUUC-Lch-049646	Latimeria chalumnae	47.74	1.00e-121	430.00
IUUC-Loc-052022	Lepisosteus oculatus	78.06	3.00e-86	312.00
IUUC-Laf-054579	Loxodonta africana	51.11	2.00e-157	549.00
IUUC-Mcc-055315	Macaca mulatta	52.06	1.00e-161	563.00
IUUC-Meu-056288	Macropus eugenii	53.89	6.00e-135	474.00
IUUC-Mmr-061639	Microcebus murinus	56.65	8.00e-149	520.00
IUUC-Mdo-062072	Monodelphis domestica	55.13	3.00e-139	488.00
IUUC-Mmu-063622	Mus musculus	50.48	3.00e-152	531.00
IUUC-Mpu-066737	Mustela putorius furo	54.14	2.00e-153	535.00
IUUC-Mlu-068173	Myotis lucifugus	56.84	3.00e-148	518.00
IUUC-Opr-070432	Ochotona princeps	49.59	1.00e-142	499.00
IUUC-Ont-072160	Oreochromis niloticus	47.76	9.00e-107	380.00
IUUC-Oan-072691	Ornithorhynchus anatinus	51.09	3.00e-124	438.00
IUUC-Ocu-073798	Oryctolagus cuniculus	51.11	4.00e-156	545.00
IUUC-Ola-086367	Oryzias latipes	48.87	1.00e-110	393.00
IUUC-Oga-088231	Otolemur garnettii	51.43	1.00e-158	553.00
IUUC-Oar-089227	Ovis aries	49.68	7.00e-148	517.00
IUUC-Ptr-091460	Pan troglodytes	52.38	6.00e-162	563.00
IUUC-Pan-092713	Papio anubis	52.06	1.00e-161	563.00
IUUC-Pfo-096468	Poecilia formosa	48.86	1.00e-111	396.00
IUUC-Pab-098357	Pongo abelii	52.38	4.00e-162	564.00
IUUC-Pca-100837	Procavia capensis	55.79	6.00e-146	510.00
IUUC-Pva-103249	Pteropus vampyrus	55.11	3.00e-139	488.00
IUUC-Rno-106086	Rattus norvegicus	50.65	1.00e-152	533.00
IUUC-Sha-107245	Sarcophilus harrisii	55.13	3.00e-139	488.00
IUUC-Sar-112985	Sorex araneus	57.03	8.00e-149	520.00
IUUC-Ssc-115756	Sus scrofa	56.84	1.00e-148	520.00
IUUC-Tru-117644	Takifugu rubripes	49.09	2.00e-114	406.00
IUUC-Tni-120245	Tetraodon nigroviridis	49.59	3.00e-112	399.00
IUUC-Tbe-127472	Tupaia belangeri	97.65	3.00e-121	428.00
IUUC-Ttr-128953	Tursiops truncatus	90.75	9.00e-118	417.00
IUUC-Vpa-130683	Vicugna pacos	52.32	9.00e-141	493.00
IUUC-Xtr-132827	Xenopus tropicalis	48.77	8.00e-112	397.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence