iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Hsa-046185

Ensembl Protein ID

ENSP00000483614.1

UniProt Accession

A0A087X0R7; A0A087X0R7_HUMAN

Genbank Protein ID

ENSP00000483614

Protein Name

SENP3-EIF4A1 readthrough (NMD candidate)

Genbank Nucleotide ID

AC016876

Gene Name

SENP3-EIF4A1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSG00000277957.1	ENST00000614237.1	ENSP00000483614.1

Annotation

mRNA Expression
ICGC
DNA & RNA Element
circBase	CircNet	SomamiR
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/ULP	1.40e-51	176.8	317	472

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/ULP

   S: 2    svtnedlkcLeegeflnDviidfylkylvleklkkekverihifssffykklkqkerrrvktwtrkvdlfekdlifvpineaaHWslavvcf 93
            +t++dl +L  +++lnD+++++y + lv++++     e++h+f+sffy+kl++k+++ vk+wt++vd+f+k+l+++pi+ ++HWsl+ v++
   Q: 317  VLTMDDLGTLYGQNWLNDQVMNMYGD-LVMDTVP----EKVHFFNSFFYDKLRTKGYDGVKRWTKNVDIFNKELLLIPIHLEVHWSLISVDV 403
           589***********************.******7....99**************************************************** PP
   S: 94   kkksilllDSlrgasksnvvkklreylevevkkkskrefskeklkgsnpk.vpqQkNssDCGvyvlqyves 163
           ++++i+++DS+ ++ ++++ k++++yl+ e+ kk++ +f++  +kg++++ v++Q+N+sDCG++vlqy+++
   Q: 404  RRRTITYFDSQ-RTLNRRCPKHIAKYLQAEAVKKDRLDFHQ-GWKGYFKMnVARQNNDSDCGAFVLQYCKH 472
           ***********.999*************************9.9***99988******************97 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

DASASEEEEE EEEEEDEDEE EEVAAWRLPP RWSQLGTSQR PRPSRPTHRK TCSQRRRRAM 60
RAFRMLLYSK STSLTFHWKL WGRHRGRRRG LAHPKNHLSP QQGGATPQVP SPCCRFDSPR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATGCCTCAG CAAGTGAAGA GGAGGAAGAA GAGGAGGAGG AGGAGGATGA AGATGAAGAG 60
GAGGAAGTGG CAGCTTGGAG GCTGCCCCCA AGATGGAGTC AGCTGGGAAC CTCCCAGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003653--Peptidase_C48_C

PROSITE

PS50600--ULP_PROTEASE

Pfam

PF02902--Peptidase_C48

Gene Ontology

GO:0005634--C:nucleus
GO:0004175--F:endopeptidase activity
GO:0016929--F:SUMO-specific protease activity
GO:0016926--P:protein desumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004862	Anolis carolinensis	63.21	9.00e-150	523.00
IUUC-Ame-011239	Astyanax mexicanus	77.66	6.00e-131	461.00
IUUC-Dre-028347	Danio rerio	72.12	4.00e-134	471.00
IUUC-Dor-030264	Dipodomys ordii	95.52	0.00e+00	800.00
IUUC-Ete-032386	Echinops telfairi	97.00	0.00e+00	723.00
IUUC-Gmo-038794	Gadus morhua	79.31	2.00e-125	441.00
IUUC-Gac-041935	Gasterosteus aculeatus	78.16	3.00e-126	444.00
IUUC-Lch-050003	Latimeria chalumnae	59.40	2.00e-145	508.00
IUUC-Loc-052486	Lepisosteus oculatus	71.81	2.00e-137	483.00
IUUC-Psi-093896	Pelodiscus sinensis	57.98	5.00e-127	447.00
IUUC-Pfo-096403	Poecilia formosa	74.38	2.00e-125	442.00
IUUC-Pca-101098	Procavia capensis	97.61	0.00e+00	686.00
IUUC-Sar-113602	Sorex araneus	87.63	9.00e-158	549.00
IUUC-Tru-117778	Takifugu rubripes	75.35	2.00e-130	459.00
IUUC-Tsy-119369	Tarsius syrichta	97.01	0.00e+00	699.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence