iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059275

UUCD1 version

UUC-MeG-00461

Ensembl Protein ID

ENSMGAP00000010461.2

UniProt Accession

G1NCI3; G1NCI3_MELGA

Protein Name

Uncharacterized protein

Gene Name

FBXW4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000010100.2	ENSMGAT00000011319.2	ENSMGAP00000010461.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.10e-23	80.3	112	144
UBD/Beta-Prp	3.00e-42	144.5	181	319

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrtgv 34
           H+ +v+c++f+++l+vsGs+D t kvW+l+ g+
   Q: 112  HEQEVNCVDFQGGLIVSGSRDRTAKVWSLSAGR 144
           99********669***************99887 PP

UBD/Beta-Prp

   S: 159  rtvrlWdlktgkllrtl.tgghtdsvyslsfdsngkelvsgsldgtvklwdlq..tgecvrtlng.htdnvksvrfspnderlvsgs.s 242
           + +r+Wd ++g+ll+ l t  h+++     f ++   l+s+++d+++++wd++  t +cvr++++ h++  +++r++  ++ ++sgs  
   Q: 181  SPLRIWDFESGQLLTCLgTDFHHGAGVLDVFYETPSLLLSCGYDTYIRYWDIRtsTRKCVREWEEpHDSALYCIRTD-GNHMIASGSsY 268
           568**************7555666666666888899*****************9999*******9999*********.99999999978 PP
   S: 243  DgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwkl 294
            g++r+Wd+r+ ++l+++ l+  ++++v +l+f+  +l+++ + s ++++++
   Q: 269  YGVVRLWDKRQTQCLQSFHLSSPTSSPVYCLRFSTTHLYAALA-SALHVLDF 319
           9*********************************999988755.55666655 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

GIPVKERVKV SQNWRHGRCR RETVLKWKCN LMPWMELDGQ YLYLSQAENI QAYQLCPDGT 60
GLQRHPQAIF SGHQEDVCRF VLVNSHIVSG GGDGNIVLHK IHGSYSVKFS AHEQEVNCVD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCATTCCAG TGAAGGAAAG GGTGAAAGTC TCTCAAAACT GGAGGCATGG ACGCTGCCGG 60
AGGGAGACAG TCCTGAAATG GAAATGCAAG CAAGTGGCTC TGTTCTCTTC TACTTGGTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0051216--P:cartilage development
GO:0042733--P:embryonic digit morphogenesis
GO:0002053--P:positive regulation of mesenchymal cell proliferation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002129	Ailuropoda melanoleuca	73.35	2.00e-144	504.00
IUUC-Apl-003837	Anas platyrhynchos	98.13	0.00e+00	654.00
IUUC-Aca-004776	Anolis carolinensis	82.92	3.00e-146	511.00
IUUC-Ame-010651	Astyanax mexicanus	65.02	8.00e-121	426.00
IUUC-Bta-013495	Bos taurus	72.73	5.00e-136	477.00
IUUC-Cja-018901	Callithrix jacchus	73.04	4.00e-136	477.00
IUUC-Cfa-021251	Canis familiaris	73.04	2.00e-143	502.00
IUUC-Cpo-021750	Cavia porcellus	73.98	3.00e-144	504.00
IUUC-Csa-024026	Chlorocebus sabaeus	73.04	9.00e-144	503.00
IUUC-Cho-024496	Choloepus hoffmanni	54.23	5.00e-96	343.00
IUUC-Cin-025142	Ciona intestinalis	32.28	7.00e-21	93.60
IUUC-Csv-025883	Ciona savignyi	38.81	9.00e-66	243.00
IUUC-Dre-027447	Danio rerio	66.35	6.00e-124	436.00
IUUC-Dno-029572	Dasypus novemcinctus	65.05	2.00e-122	432.00
IUUC-Dor-030982	Dipodomys ordii	73.36	3.00e-129	454.00
IUUC-Dme-031804	Drosophila melanogaster	22.02	3.00e-13	69.30
IUUC-Ete-032917	Echinops telfairi	73.75	3.00e-145	507.00
IUUC-Eca-033969	Equus caballus	73.04	2.00e-136	478.00
IUUC-Eeu-034850	Erinaceus europaeus	67.81	9.00e-127	446.00
IUUC-Fca-036182	Felis catus	73.35	3.00e-144	504.00
IUUC-Fal-037391	Ficedula albicollis	95.34	0.00e+00	627.00
IUUC-Gmo-038632	Gadus morhua	62.50	2.00e-116	411.00
IUUC-Gga-040783	Gallus gallus	99.38	0.00e+00	665.00
IUUC-Gac-042314	Gasterosteus aculeatus	59.19	4.00e-97	347.00
IUUC-Ggo-044739	Gorilla gorilla	73.35	3.00e-143	500.00
IUUC-Hsa-046705	Homo sapiens	73.35	3.00e-136	477.00
IUUC-Itr-048014	Ictidomys tridecemlineatus	73.43	1.00e-127	448.00
IUUC-Loc-052397	Lepisosteus oculatus	75.79	8.00e-140	489.00
IUUC-Laf-054544	Loxodonta africana	73.60	2.00e-144	504.00
IUUC-Meu-056363	Macropus eugenii	60.69	3.00e-99	354.00
IUUC-Mmr-060906	Microcebus murinus	72.73	2.00e-142	499.00
IUUC-Mdo-062400	Monodelphis domestica	81.76	3.00e-158	550.00
IUUC-Mmu-063556	Mus musculus	74.06	1.00e-143	502.00
IUUC-Mpu-066500	Mustela putorius furo	73.04	8.00e-144	503.00
IUUC-Mlu-068074	Myotis lucifugus	73.35	4.00e-144	503.00
IUUC-Nle-069601	Nomascus leucogenys	73.35	2.00e-143	501.00
IUUC-Opr-070904	Ochotona princeps	65.11	7.00e-92	330.00
IUUC-Ont-072679	Oreochromis niloticus	61.13	2.00e-116	412.00
IUUC-Oan-073434	Ornithorhynchus anatinus	77.51	3.00e-69	254.00
IUUC-Ocu-074649	Oryctolagus cuniculus	73.67	2.00e-144	504.00
IUUC-Ola-087336	Oryzias latipes	54.97	3.00e-93	334.00
IUUC-Oga-088590	Otolemur garnettii	71.88	2.00e-134	471.00
IUUC-Oar-090178	Ovis aries	73.04	1.00e-135	475.00
IUUC-Pan-092881	Papio anubis	73.04	2.00e-143	501.00
IUUC-Pfo-096176	Poecilia formosa	59.69	1.00e-101	363.00
IUUC-Pab-098285	Pongo abelii	73.35	3.00e-143	501.00
IUUC-Pca-100888	Procavia capensis	70.00	4.00e-129	454.00
IUUC-Pva-102184	Pteropus vampyrus	61.25	9.00e-112	396.00
IUUC-Rno-105668	Rattus norvegicus	72.41	2.00e-141	494.00
IUUC-Sha-106629	Sarcophilus harrisii	82.08	2.00e-159	554.00
IUUC-Ssc-116183	Sus scrofa	73.98	3.00e-145	508.00
IUUC-Tgu-116630	Taeniopygia guttata	95.34	0.00e+00	642.00
IUUC-Tru-118761	Takifugu rubripes	57.76	4.00e-106	377.00
IUUC-Tni-120651	Tetraodon nigroviridis	54.46	4.00e-63	233.00
IUUC-Ttr-128582	Tursiops truncatus	73.35	2.00e-134	471.00
IUUC-Vpa-130431	Vicugna pacos	59.65	5.00e-74	270.00
IUUC-Xtr-132655	Xenopus tropicalis	74.92	4.00e-144	503.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence