iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118761

UUCD1 version

UUC-TaR-00058

Ensembl Protein ID

ENSTRUP00000002403.1

UniProt Accession

H2RQI8; H2RQI8_TAKRU

Protein Name

Uncharacterized protein

Gene Name

fbxw4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000001025.1	ENSTRUT00000002413.1	ENSTRUP00000002403.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/SCF/F-box	2.80e-06	28.7	3	47
E3 adaptor/Cullin RING/DCX/DWD	3.70e-19	69.2	175	204

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/F-box

   S: 103  ldrlpeeilveilklldkeellraarvcrrwqelasqkalwktvt 147
           + +lp+++l +il++ld ++l+r+++vc++++++ +++a+w++v 
   Q: 3    FLQLPDDVLYHILSYLDFKSLGRLSQVCKSTYQFLNRDAVWRNVA 47
           579*****************************99999****9985 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDl 30
           gH+ +v+cl+  + +l++sGs+D t ++W l
   Q: 175  GHKQEVNCLDTkN-GLIISGSRDQTTRIWTL 204
           8*********955.9**************75 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MLFLQLPDDV LYHILSYLDF KSLGRLSQVC KSTYQFLNRD AVWRNVAKEF LNTGITWSGT 60
DKYGHIPLKN RVRTAQNWYN GICKRATPLK WKTKLLPWLQ LDGDTLFLSQ AGEIGAYHLR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTGTTCC TCCAGCTGCC GGATGATGTT CTTTATCACA TCCTCTCATA TTTGGACTTC 60
AAGTCTCTCG GTCGCCTATC TCAAGTTTGT AAAAGTACTT ACCAGTTTTT GAACCGCGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001810--F-box_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00646--F-box
PF00400--WD40

SMART

SM00256--FBOX
SM00320--WD40

Gene Ontology

GO:0019005--C:SCF ubiquitin ligase complex
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

KEGG

tru:101077843

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002129	Ailuropoda melanoleuca	53.10	2.00e-121	429.00
IUUC-Apl-003837	Anas platyrhynchos	57.50	2.00e-113	402.00
IUUC-Aca-004776	Anolis carolinensis	54.01	2.00e-113	402.00
IUUC-Ame-010651	Astyanax mexicanus	60.12	2.00e-115	408.00
IUUC-Bta-013495	Bos taurus	53.10	4.00e-117	414.00
IUUC-Cja-018901	Callithrix jacchus	52.46	2.00e-114	405.00
IUUC-Cfa-021251	Canis familiaris	53.37	1.00e-121	430.00
IUUC-Cpo-021750	Cavia porcellus	53.29	1.00e-105	376.00
IUUC-Csa-024026	Chlorocebus sabaeus	52.73	1.00e-118	420.00
IUUC-Cho-024496	Choloepus hoffmanni	40.71	1.00e-79	290.00
IUUC-Cin-025142	Ciona intestinalis	23.11	1.00e-18	86.30
IUUC-Csv-025883	Ciona savignyi	36.18	7.00e-65	241.00
IUUC-Dre-027447	Danio rerio	60.72	6.00e-137	480.00
IUUC-Dno-029572	Dasypus novemcinctus	47.84	6.00e-93	334.00
IUUC-Dor-030982	Dipodomys ordii	49.18	4.00e-106	378.00
IUUC-Dme-031804	Drosophila melanogaster	22.73	5.00e-13	68.90
IUUC-Ete-032917	Echinops telfairi	55.17	1.00e-108	385.00
IUUC-Eca-033969	Equus caballus	53.01	1.00e-115	409.00
IUUC-Eeu-034850	Erinaceus europaeus	49.73	3.00e-105	375.00
IUUC-Fca-036182	Felis catus	51.48	2.00e-113	402.00
IUUC-Fal-037391	Ficedula albicollis	53.28	9.00e-118	416.00
IUUC-Gmo-038632	Gadus morhua	71.09	8.00e-169	586.00
IUUC-Gga-040783	Gallus gallus	55.61	2.00e-124	438.00
IUUC-Gac-042314	Gasterosteus aculeatus	75.52	2.00e-154	538.00
IUUC-Ggo-044739	Gorilla gorilla	52.46	1.00e-118	419.00
IUUC-Hsa-046705	Homo sapiens	52.19	3.00e-114	404.00
IUUC-Itr-048014	Ictidomys tridecemlineatus	55.59	5.00e-96	343.00
IUUC-Loc-052397	Lepisosteus oculatus	62.27	2.00e-128	451.00
IUUC-Laf-054544	Loxodonta africana	52.85	1.00e-106	379.00
IUUC-Meu-056363	Macropus eugenii	44.83	1.00e-74	273.00
IUUC-Mga-059275	Meleagris gallopavo	57.76	1.00e-113	402.00
IUUC-Mmr-060906	Microcebus murinus	53.01	9.00e-119	420.00
IUUC-Mdo-062400	Monodelphis domestica	54.18	9.00e-123	433.00
IUUC-Mmu-063556	Mus musculus	52.73	8.00e-117	413.00
IUUC-Mpu-066500	Mustela putorius furo	53.10	2.00e-121	428.00
IUUC-Mlu-068074	Myotis lucifugus	54.55	2.00e-108	385.00
IUUC-Nle-069601	Nomascus leucogenys	52.46	1.00e-118	419.00
IUUC-Opr-070904	Ochotona princeps	45.16	2.00e-72	265.00
IUUC-Ont-072679	Oreochromis niloticus	71.43	3.00e-158	551.00
IUUC-Oan-073434	Ornithorhynchus anatinus	45.33	1.00e-50	192.00
IUUC-Ocu-074649	Oryctolagus cuniculus	52.19	4.00e-116	411.00
IUUC-Ola-087336	Oryzias latipes	65.62	2.00e-141	494.00
IUUC-Oga-088590	Otolemur garnettii	51.91	2.00e-112	399.00
IUUC-Oar-090178	Ovis aries	51.34	2.00e-108	385.00
IUUC-Pan-092881	Papio anubis	53.01	3.00e-119	421.00
IUUC-Pfo-096176	Poecilia formosa	72.32	1.00e-152	532.00
IUUC-Pab-098285	Pongo abelii	52.46	3.00e-118	419.00
IUUC-Pca-100888	Procavia capensis	48.52	2.00e-104	372.00
IUUC-Pva-102184	Pteropus vampyrus	44.81	9.00e-95	340.00
IUUC-Rno-105668	Rattus norvegicus	52.46	6.00e-117	414.00
IUUC-Sha-106629	Sarcophilus harrisii	55.17	5.00e-110	390.00
IUUC-Ssc-116183	Sus scrofa	53.37	3.00e-121	428.00
IUUC-Tgu-116630	Taeniopygia guttata	55.76	7.00e-131	460.00
IUUC-Tni-120651	Tetraodon nigroviridis	82.91	1.00e-97	348.00
IUUC-Ttr-128582	Tursiops truncatus	53.10	2.00e-115	409.00
IUUC-Vpa-130431	Vicugna pacos	46.05	4.00e-54	204.00
IUUC-Xtr-132655	Xenopus tropicalis	54.72	2.00e-122	431.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence