iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000015042.2	ENSCJAT00000000550.2	ENSCJAP00000000513.2
ENSCJAG00000015042.2	ENSCJAT00000029310.2	ENSCJAP00000027737.2
ENSCJAG00000015042.2	ENSCJAT00000000537.2	ENSCJAP00000000500.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.10e-35	118.1	140	177
UBD/Beta-Prp	2.00e-54	185.7	242	499

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH + v+c+af  + +++ +GsdD+ +k+W+++ g+ll
   Q: 140  GHLSAVYCVAFdRTgHRIFTGSDDCLVKIWSTHNGRLL 177
           8**********955599***************999987 PP

UBD/Beta-Prp

   S: 22   ksllatgsrdgtikvwdvttgkl......lrslsgheaevtavk..fspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvlsl 100
           +++++++++dgt+  w+++ ++l      l+  ++  ++v+ ++  fs  g +l+tgs+D++i+ +   +++++ +  l+ h+d+v s+
   Q: 242  QRYMVSTGADGTVCFWQWDLESLkfsprpLKFTEKPRPGVQMLCssFSVGGMFLATGSTDHVIRMYflGFEAPEKIAELESHTDKVDSI 330
           689*****************99999988777778888888755522888888**************99999****************** PP
   S: 101  sfspsgdklvsGshdrtirvwdletgqclee...............tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrt 174
           +f+ sgd+++sGs+d t+r+w  e+ ++ +                 ++  +  v++++++++++++v++ +D ++++W++ tg+ll+ 
   Q: 331  QFCNSGDRFLSGSRDGTARIWRFEQLEWRSIlldmstrisgdlsseEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHN 419
           *************************999988999********998877777888*********************************** PP
   S: 175  ltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiriW 249
           l g h d v  l+   fds  + ++s+++dg++ +wd+ +g+ ++ + +         v + +fs+++++++++ s+g + i+
   Q: 420  LLG-HADEVFVLEthpFDS--RIMLSAGHDGSIFIWDITKGTKMKHYFNMIegqghGAVFDCKFSQDGQHFACTDSHGHLLIF 499
           **9.*********555555..99****************999977766544444456677789999*****999999998886 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

FQLLPKRLDW EGNEHNRSYE ELVLSNKHVA PDHLLQICQR IGPMLDKEIP PSISRVTSLL 60
GAGRQSLLRT AKDCRHTVWK GSAFAALHRG RPPEMPVNYG SPPNLVEIHR GKQLTGCSTF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGAGC CCTCGTCCGC CCGACGCCCG GTGCCTCTCA TCGAGTCGGG TAAGACGCAG 60
GGCCTTGCCA CCCCTTCCCC CGGCGCCCCC GCTGCTTCGG CTCCCCTGGC CGCTCCCCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0007010--P:cytoskeleton organization
GO:0008360--P:regulation of cell shape
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002332	Ailuropoda melanoleuca	84.67	0.00e+00	3294.00
IUUC-Apl-004083	Anas platyrhynchos	69.24	0.00e+00	1966.00
IUUC-Ame-010718	Astyanax mexicanus	70.71	0.00e+00	1129.00
IUUC-Bta-013217	Bos taurus	87.66	0.00e+00	3618.00
IUUC-Cfa-021037	Canis familiaris	87.80	0.00e+00	3564.00
IUUC-Cpo-021934	Cavia porcellus	91.76	0.00e+00	2736.00
IUUC-Csa-023352	Chlorocebus sabaeus	94.92	0.00e+00	3743.00
IUUC-Cho-024690	Choloepus hoffmanni	78.15	0.00e+00	1337.00
IUUC-Cin-025553	Ciona intestinalis	39.07	3.00e-109	389.00
IUUC-Dre-028205	Danio rerio	68.55	0.00e+00	1107.00
IUUC-Dno-028938	Dasypus novemcinctus	85.22	0.00e+00	3543.00
IUUC-Ete-032650	Echinops telfairi	58.68	0.00e+00	1229.00
IUUC-Eca-034349	Equus caballus	88.44	0.00e+00	3529.00
IUUC-Fca-035485	Felis catus	82.36	0.00e+00	3115.00
IUUC-Fal-037307	Ficedula albicollis	70.79	0.00e+00	2384.00
IUUC-Gga-040865	Gallus gallus	76.67	0.00e+00	2291.00
IUUC-Ggo-045500	Gorilla gorilla	95.78	0.00e+00	3964.00
IUUC-Hsa-046350	Homo sapiens	95.78	0.00e+00	3976.00
IUUC-Itr-047962	Ictidomys tridecemlineatus	94.75	0.00e+00	1171.00
IUUC-Lch-049662	Latimeria chalumnae	57.20	0.00e+00	2069.00
IUUC-Loc-052853	Lepisosteus oculatus	73.87	0.00e+00	1161.00
IUUC-Laf-053848	Loxodonta africana	86.32	0.00e+00	3501.00
IUUC-Mcc-054638	Macaca mulatta	95.25	0.00e+00	3941.00
IUUC-Meu-056739	Macropus eugenii	79.77	0.00e+00	1116.00
IUUC-Mga-060165	Meleagris gallopavo	77.59	0.00e+00	2272.00
IUUC-Mmr-061227	Microcebus murinus	90.96	0.00e+00	3757.00
IUUC-Mdo-062074	Monodelphis domestica	69.18	0.00e+00	2753.00
IUUC-Mmu-064075	Mus musculus	82.42	0.00e+00	2972.00
IUUC-Mpu-066643	Mustela putorius furo	88.52	0.00e+00	3012.00
IUUC-Mlu-067735	Myotis lucifugus	85.80	0.00e+00	3483.00
IUUC-Nle-069402	Nomascus leucogenys	95.30	0.00e+00	3099.00
IUUC-Ont-072298	Oreochromis niloticus	62.27	0.00e+00	1815.00
IUUC-Oan-072954	Ornithorhynchus anatinus	69.44	0.00e+00	2788.00
IUUC-Ocu-074456	Oryctolagus cuniculus	87.60	0.00e+00	3680.00
IUUC-Ola-086648	Oryzias latipes	58.24	0.00e+00	1601.00
IUUC-Olu-087745	Ostreococcus lucimarinus	28.76	6.00e-57	216.00
IUUC-Oga-087938	Otolemur garnettii	82.46	0.00e+00	3201.00
IUUC-Oar-090214	Ovis aries	86.96	0.00e+00	3536.00
IUUC-Ptr-091213	Pan troglodytes	95.78	0.00e+00	3927.00
IUUC-Pan-092444	Papio anubis	94.24	0.00e+00	3916.00
IUUC-Psi-093271	Pelodiscus sinensis	60.18	0.00e+00	2236.00
IUUC-Pfo-097318	Poecilia formosa	62.68	0.00e+00	1764.00
IUUC-Pab-097573	Pongo abelii	94.46	0.00e+00	3860.00
IUUC-Pca-100759	Procavia capensis	72.80	0.00e+00	1110.00
IUUC-Pva-102782	Pteropus vampyrus	87.26	0.00e+00	3586.00
IUUC-Rno-105687	Rattus norvegicus	78.01	0.00e+00	3222.00
IUUC-Sha-107061	Sarcophilus harrisii	58.70	0.00e+00	1631.00
IUUC-Sar-113519	Sorex araneus	80.37	0.00e+00	1787.00
IUUC-Tgu-116513	Taeniopygia guttata	77.75	0.00e+00	2280.00
IUUC-Tru-117824	Takifugu rubripes	58.22	0.00e+00	1637.00
IUUC-Tsy-118921	Tarsius syrichta	90.19	0.00e+00	2045.00
IUUC-Tni-120656	Tetraodon nigroviridis	58.39	0.00e+00	1597.00
IUUC-Tbe-127663	Tupaia belangeri	78.41	0.00e+00	1317.00
IUUC-Ttr-128561	Tursiops truncatus	85.07	0.00e+00	3366.00
IUUC-Vpa-130444	Vicugna pacos	84.85	0.00e+00	3315.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence