iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lma-053245

Ensembl Protein ID

CBY00394

UniProt Accession

E5A9Q3; E5A9Q3_LEPMJ

Genbank Protein ID

CBY00394.1

Protein Name

Similar to HECT domain protein

Genbank Nucleotide ID

FP929138

Gene Name

LEMA_P015240.1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
LEMA_P015240.1	CBY00394	CBY00394

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.80e-62	211.0	957	1290

Active Site

Position(s)	Description	Evidence
1260	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 12   efvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyklllgk....... 103
           e +g+ g+dlgGvt+e+++l++ e ++p++g+f+ +++ + t++ +p s     e    Fe++G l  +a+++g  l+++++ +fy ++l+        
   Q: 957  EDTGDYGTDLGGVTNEYFSLVLGEAFRPENGMFTIDPQTRMTWF-QPGSL----EAPWKFEMIGLLFSIAVYNGVTLPVTFPLAFYHMMLSPvdssked 1050
           456788******************************99888877.78887....67899******************************9887777777 PP
   S: 104  ...klsledleevdpelykslkeikenaesdieelgldltfsvseei..........lgetkeee.LkpgGenipVtneNkeeYvklvveyrlkegike 188
                +++ +++  p+l+ks  e+++  + d+ e  +  ++  s e+          ++  +  + L  ++e + Vtn+N+ee+v +++ +    ++++
   Q: 1051 lvkISTVDFIKDGWPDLAKSFGELLSWSDGDVGEVIMRDAV-FSYEVfghridhnmaYPFGH--DpLEADSEPEVVTNANREEFVGKYIYFLTYASVET 1146
           773455577889999*****999999987766555332222.22222122233332233333..34********************************* PP
   S: 189  qveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprlf 287
           q+ af++Gf + +++++l++F++  l+ l+ G+++i++ +l++   y++gyt++s +++ Fw+v e+ ++e+ +++L+FvT s+r+P+ G ++++   f
   Q: 1147 QLVAFKKGFLTCLQPKSLRYFSPAFLRKLVEGSHDISMTALRRVVDYDEGYTPTSATVRAFWKVAESYDQEDARRLLEFVTASNRIPVTGYENVM---F 1242
           **********************************************************************************************9...9 PP
   S: 288  virk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFe 334
            i+k  ++++ lPss+TCf +L LP+Y   e+l++kL +Ai++++gF+
   Q: 1243 KISKvGGQPHALPSSSTCFGRLYLPDYADVEVLRQKLGLAITHSRGFG 1290
           999977788**************************************8 PP

Organism

Leptosphaeria maculans

Protein Sequence
(Fasta)

MTSAAKHGGT CHPCARTEPP PPLPARQPSS PALTALRTLA VGYYLGTLSF FFSTIHNSPS 60
SPAFVSLPSF DDMSAPDEGR QRARAHPRTV PGASYAPLSS RALQPRPNTV IDVQEVHRVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACATCAG CTGCCAAGCA CGGTGGCACC TGCCATCCCT GCGCCCGGAC TGAGCCACCG 60
CCACCTTTGC CCGCCCGGCA GCCGTCCTCC CCAGCCCTGA CAGCCCTACG GACCTTAGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR032353--AZUL
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF16558--AZUL
PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002214	Ailuropoda melanoleuca	33.87	3.00e-55	208.00
IUUC-Apl-003742	Anas platyrhynchos	35.11	4.00e-56	211.00
IUUC-Aca-004873	Anolis carolinensis	35.28	2.00e-55	209.00
IUUC-Acl-008265	Aspergillus clavatus	32.61	8.00e-74	271.00
IUUC-Afl-008437	Aspergillus flavus	33.14	4.00e-104	371.00
IUUC-Afu-008852	Aspergillus fumigatus	32.67	4.00e-98	351.00
IUUC-Ani-009330	Aspergillus nidulans	34.97	4.00e-76	278.00
IUUC-Ang-009616	Aspergillus niger	32.30	5.00e-103	368.00
IUUC-Aor-010162	Aspergillus oryzae	33.22	2.00e-104	372.00
IUUC-Ate-010475	Aspergillus terreus	32.98	4.00e-110	391.00
IUUC-Ame-011166	Astyanax mexicanus	35.54	7.00e-57	214.00
IUUC-Bgr-012015	Blumeria graminis	31.41	2.00e-95	342.00
IUUC-Bta-013286	Bos taurus	33.87	3.00e-55	208.00
IUUC-Bci-013608	Botrytis cinerea	33.07	2.00e-115	409.00
IUUC-Cel-018150	Caenorhabditis elegans	33.07	2.00e-49	189.00
IUUC-Cja-019707	Callithrix jacchus	33.87	2.00e-55	208.00
IUUC-Cfa-020154	Canis familiaris	33.87	3.00e-55	208.00
IUUC-Cpo-021292	Cavia porcellus	33.60	1.00e-53	202.00
IUUC-Csa-023378	Chlorocebus sabaeus	33.87	2.00e-55	208.00
IUUC-Cin-025643	Ciona intestinalis	31.76	4.00e-50	191.00
IUUC-Csv-026282	Ciona savignyi	33.16	1.00e-42	166.00
IUUC-Cgl-026488	Colletotrichum gloeosporioides	33.17	5.00e-98	351.00
IUUC-Cme-027151	Cyanidioschyzon merolae	36.32	9.00e-54	204.00
IUUC-Dre-027901	Danio rerio	35.54	4.00e-58	218.00
IUUC-Dno-029320	Dasypus novemcinctus	34.13	5.00e-56	211.00
IUUC-Dor-030756	Dipodomys ordii	34.30	7.00e-55	207.00
IUUC-Dse-031435	Dothistroma septosporum	31.30	1.00e-77	282.00
IUUC-Dme-032035	Drosophila melanogaster	34.31	4.00e-54	204.00
IUUC-Ete-032902	Echinops telfairi	34.13	4.00e-47	181.00
IUUC-Eca-033843	Equus caballus	33.33	3.00e-51	195.00
IUUC-Eeu-035109	Erinaceus europaeus	32.80	7.00e-48	184.00
IUUC-Fca-036344	Felis catus	33.87	2.00e-55	209.00
IUUC-Fal-036747	Ficedula albicollis	35.11	5.00e-56	211.00
IUUC-Fox-037915	Fusarium oxysporum	32.42	3.00e-96	344.00
IUUC-Fso-038357	Fusarium solani	31.53	3.00e-93	335.00
IUUC-Gmo-039089	Gadus morhua	35.29	1.00e-56	213.00
IUUC-Ggr-039765	Gaeumannomyces graminis	33.57	1.00e-115	410.00
IUUC-Gga-040399	Gallus gallus	35.11	4.00e-56	211.00
IUUC-Gac-041933	Gasterosteus aculeatus	34.40	2.00e-59	222.00
IUUC-Ggo-044804	Gorilla gorilla	33.87	2.00e-55	209.00
IUUC-Hsa-045727	Homo sapiens	33.87	2.00e-55	209.00
IUUC-Itr-048289	Ictidomys tridecemlineatus	33.87	4.00e-55	207.00
IUUC-Lch-050197	Latimeria chalumnae	35.20	6.00e-60	224.00
IUUC-Loc-052743	Lepisosteus oculatus	34.31	9.00e-54	203.00
IUUC-Laf-053615	Loxodonta africana	34.13	8.00e-56	210.00
IUUC-Mcc-054934	Macaca mulatta	33.87	3.00e-55	208.00
IUUC-Meu-056061	Macropus eugenii	33.87	5.00e-54	204.00
IUUC-Mor-057108	Magnaporthe oryzae	34.03	6.00e-105	374.00
IUUC-Mga-059271	Meleagris gallopavo	35.11	7.00e-56	210.00
IUUC-Mmr-061288	Microcebus murinus	33.87	2.00e-55	209.00
IUUC-Mdo-062975	Monodelphis domestica	33.87	2.00e-55	209.00
IUUC-Mmu-063674	Mus musculus	33.87	4.00e-55	208.00
IUUC-Mpu-066568	Mustela putorius furo	33.87	2.00e-55	209.00
IUUC-Mlu-067522	Myotis lucifugus	33.60	3.00e-55	208.00
IUUC-Nfi-068554	Neosartorya fischeri	32.56	1.00e-106	380.00
IUUC-Ncr-068759	Neurospora crassa	32.23	8.00e-95	340.00
IUUC-Nle-069505	Nomascus leucogenys	33.87	2.00e-55	209.00
IUUC-Opr-070570	Ochotona princeps	33.01	5.00e-45	174.00
IUUC-Ont-071527	Oreochromis niloticus	34.57	1.00e-57	216.00
IUUC-Oan-072933	Ornithorhynchus anatinus	34.93	2.00e-52	199.00
IUUC-Ocu-074922	Oryctolagus cuniculus	33.87	2.00e-55	208.00
IUUC-Ola-086833	Oryzias latipes	36.70	3.00e-54	204.00
IUUC-Oga-088261	Otolemur garnettii	33.60	1.00e-54	206.00
IUUC-Oar-090024	Ovis aries	33.87	3.00e-55	208.00
IUUC-Ptr-090455	Pan troglodytes	33.87	2.00e-55	209.00
IUUC-Pan-092067	Papio anubis	35.47	5.00e-53	201.00
IUUC-Psi-092974	Pelodiscus sinensis	34.84	8.00e-56	210.00
IUUC-Pma-094643	Petromyzon marinus	34.19	2.00e-56	212.00
IUUC-Pno-094886	Phaeosphaeria nodorum	47.59	0.00e+00	1048.00
IUUC-Pfo-096905	Poecilia formosa	33.42	2.00e-56	212.00
IUUC-Pab-097840	Pongo abelii	33.87	3.00e-53	202.00
IUUC-Pva-103040	Pteropus vampyrus	35.76	2.00e-54	206.00
IUUC-Pte-104055	Pyrenophora teres	48.27	0.00e+00	929.00
IUUC-Pyt-104647	Pyrenophora triticirepentis	48.14	0.00e+00	1051.00
IUUC-Rno-105453	Rattus norvegicus	34.13	1.00e-55	209.00
IUUC-Sha-107651	Sarcophilus harrisii	33.87	2.00e-55	209.00
IUUC-Ssl-108420	Sclerotinia sclerotiorum	32.38	3.00e-118	418.00
IUUC-Sar-113293	Sorex araneus	35.11	4.00e-55	207.00
IUUC-Ssc-115979	Sus scrofa	33.87	2.00e-55	208.00
IUUC-Tgu-116901	Taeniopygia guttata	35.11	4.00e-56	211.00
IUUC-Tru-118368	Takifugu rubripes	35.11	2.00e-57	215.00
IUUC-Tsy-119516	Tarsius syrichta	31.12	9.00e-42	163.00
IUUC-Tni-120143	Tetraodon nigroviridis	35.11	2.00e-57	216.00
IUUC-Tre-121985	Trichoderma reesei	33.71	2.00e-101	362.00
IUUC-Tvi-122335	Trichoderma virens	38.46	5.00e-92	331.00
IUUC-Tme-127119	Tuber melanosporum	31.49	3.00e-71	262.00
IUUC-Tbe-127640	Tupaia belangeri	31.72	2.00e-35	143.00
IUUC-Ttr-129078	Tursiops truncatus	33.87	5.00e-54	204.00
IUUC-Vda-129880	Verticillium dahliae	33.92	9.00e-104	370.00
IUUC-Vpa-130448	Vicugna pacos	30.91	5.00e-44	171.00
IUUC-Xtr-132881	Xenopus tropicalis	35.11	4.00e-60	224.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence