iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dre-027749

Ensembl Protein ID

ENSDARP00000079966.5

UniProt Accession

A5WUM0; A5WUM0_DANRE

Genbank Protein ID

CAN88774.1

Protein Name

Non-specific serine/threonine protein kinase

Genbank Nucleotide ID

CU019641

Gene Name

prkaa1; DKEY-226M8.8-001

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000060596.5	ENSDART00000085531.5	ENSDARP00000079966.5

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	51.58	3.00e-121	432.00	IUUC-Ath-007014
UBD/Alpha-Helix/UBA	41.54	5.00e-104	372.00	IUUC-Spo-108202

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Danio rerio

Protein Sequence
(Fasta)

MATDKQKHEG RVKIGHYILG DTLGVGTFGK VKVGQHELTK HQVAVKILNR QKIRSLDVVG 60
KIRREIQNLK LFRHPHIIKL YQVISTPTDI FMVMEYVSGG ELFDYICKNG KLDEKESRRL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGTAGGGCC TCAGAGCGAA GATGGCGACG GACAAACAGA AACATGAAGG CAGGGTGAAA 60
ATTGGACATT ATATACTGGG AGACACGCTA GGAGTGGGGA CGTTCGGAAA AGTCAAAGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR032270--AMPK_C
IPR028375--KA1/Ssp2_C
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF16579--AdenylateSensor
PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0035556--P:intracellular signal transduction
GO:0006468--P:protein phosphorylation

KEGG

dre:100001198

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000713	Aegilops tauschii	47.12	1.00e-118	421.00
IUUC-Aml-001907	Ailuropoda melanoleuca	83.62	0.00e+00	918.00
IUUC-Atr-002770	Amborella trichopoda	46.87	5.00e-121	427.00
IUUC-Apl-003395	Anas platyrhynchos	70.64	0.00e+00	752.00
IUUC-Aca-004480	Anolis carolinensis	73.80	0.00e+00	768.00
IUUC-Aly-006289	Arabidopsis lyrata	47.21	5.00e-122	431.00
IUUC-Ath-007014	Arabidopsis thaliana	51.58	6.00e-123	434.00
IUUC-Ago-007957	Ashbya gossypii	41.68	2.00e-111	396.00
IUUC-Acl-008103	Aspergillus clavatus	60.07	8.00e-100	358.00
IUUC-Afl-008555	Aspergillus flavus	59.35	3.00e-100	359.00
IUUC-Afu-008949	Aspergillus fumigatus	59.71	1.00e-99	358.00
IUUC-Ani-009408	Aspergillus nidulans	61.42	1.00e-99	357.00
IUUC-Ang-009551	Aspergillus niger	60.07	6.00e-101	362.00
IUUC-Aor-010176	Aspergillus oryzae	59.35	3.00e-100	359.00
IUUC-Ate-010287	Aspergillus terreus	59.71	1.00e-99	357.00
IUUC-Ame-011019	Astyanax mexicanus	71.78	0.00e+00	792.00
IUUC-Bgr-012045	Blumeria graminis	59.71	2.00e-101	363.00
IUUC-Bta-012786	Bos taurus	83.80	0.00e+00	919.00
IUUC-Bci-013774	Botrytis cinerea	45.84	1.00e-101	363.00
IUUC-Bdi-014319	Brachypodium distachyon	50.93	8.00e-119	421.00
IUUC-Bol-016242	Brassica oleracea	48.86	1.00e-124	439.00
IUUC-Bra-016750	Brassica rapa	49.07	6.00e-125	441.00
IUUC-Cel-018518	Caenorhabditis elegans	56.80	2.00e-169	589.00
IUUC-Cja-019386	Callithrix jacchus	70.19	0.00e+00	791.00
IUUC-Cfa-020177	Canis familiaris	83.03	0.00e+00	890.00
IUUC-Cpo-021805	Cavia porcellus	70.91	0.00e+00	790.00
IUUC-Cre-022915	Chlamydomonas reinhardtii	54.21	6.00e-91	327.00
IUUC-Csa-024267	Chlorocebus sabaeus	71.08	0.00e+00	789.00
IUUC-Cho-024859	Choloepus hoffmanni	80.54	0.00e+00	876.00
IUUC-Cin-025550	Ciona intestinalis	59.19	0.00e+00	642.00
IUUC-Csv-026139	Ciona savignyi	59.44	0.00e+00	657.00
IUUC-Cne-027044	Cryptococcus neoformans	60.97	9.00e-103	368.00
IUUC-Cme-027289	Cyanidioschyzon merolae	45.62	1.00e-108	386.00
IUUC-Dno-030006	Dasypus novemcinctus	83.04	0.00e+00	916.00
IUUC-Dor-030578	Dipodomys ordii	70.54	0.00e+00	791.00
IUUC-Dse-031507	Dothistroma septosporum	61.94	4.00e-104	372.00
IUUC-Dme-031704	Drosophila melanogaster	55.03	2.00e-171	595.00
IUUC-Ete-033055	Echinops telfairi	80.68	0.00e+00	906.00
IUUC-Eca-034239	Equus caballus	82.99	0.00e+00	885.00
IUUC-Fca-035754	Felis catus	80.81	0.00e+00	908.00
IUUC-Fal-037363	Ficedula albicollis	85.17	0.00e+00	921.00
IUUC-Fox-038073	Fusarium oxysporum	56.85	1.00e-100	360.00
IUUC-Fso-038236	Fusarium solani	56.16	3.00e-97	349.00
IUUC-Gmo-039633	Gadus morhua	85.29	0.00e+00	977.00
IUUC-Ggr-039987	Gaeumannomyces graminis	58.57	2.00e-101	363.00
IUUC-Gga-040546	Gallus gallus	71.11	0.00e+00	799.00
IUUC-Gac-041822	Gasterosteus aculeatus	70.24	0.00e+00	761.00
IUUC-Gma-042712	Glycine max	51.03	1.00e-121	430.00
IUUC-Ggo-044797	Gorilla gorilla	83.28	0.00e+00	916.00
IUUC-Hsa-045867	Homo sapiens	83.10	0.00e+00	915.00
IUUC-Hvu-047406	Hordeum vulgare	47.05	1.00e-120	426.00
IUUC-Itr-048134	Ictidomys tridecemlineatus	71.08	0.00e+00	793.00
IUUC-Kpa-049190	Komagataella pastoris	43.42	7.00e-114	404.00
IUUC-Lch-049623	Latimeria chalumnae	85.34	0.00e+00	919.00
IUUC-Lpe-051392	Leersia perrieri	47.13	4.00e-122	431.00
IUUC-Loc-052362	Lepisosteus oculatus	91.15	0.00e+00	951.00
IUUC-Lma-053054	Leptosphaeria maculans	60.43	7.00e-106	378.00
IUUC-Laf-053799	Loxodonta africana	83.28	0.00e+00	922.00
IUUC-Mcc-055862	Macaca mulatta	70.36	0.00e+00	794.00
IUUC-Mor-057170	Magnaporthe oryzae	59.64	5.00e-103	369.00
IUUC-Mpo-057302	Magnaporthe poae	58.57	2.00e-101	363.00
IUUC-Mtr-058236	Medicago truncatula	49.46	8.00e-122	431.00
IUUC-Mla-059058	Melampsora laricipopulina	60.22	1.00e-95	343.00
IUUC-Mga-059206	Meleagris gallopavo	70.51	0.00e+00	742.00
IUUC-Mvi-060337	Microbotryum violaceum	61.80	7.00e-98	352.00
IUUC-Mmr-061761	Microcebus murinus	83.28	0.00e+00	917.00
IUUC-Mdo-062160	Monodelphis domestica	71.13	0.00e+00	793.00
IUUC-Mmu-063406	Mus musculus	70.96	0.00e+00	788.00
IUUC-Mac-064518	Musa acuminata	43.90	4.00e-113	402.00
IUUC-Mpu-066326	Mustela putorius furo	70.40	0.00e+00	737.00
IUUC-Mlu-068227	Myotis lucifugus	83.92	0.00e+00	889.00
IUUC-Nfi-068493	Neosartorya fischeri	59.71	7.00e-100	358.00
IUUC-Ncr-068665	Neurospora crassa	60.28	3.00e-105	376.00
IUUC-Nle-070158	Nomascus leucogenys	70.36	0.00e+00	795.00
IUUC-Opr-070272	Ochotona princeps	80.65	0.00e+00	904.00
IUUC-Ont-072027	Oreochromis niloticus	85.99	0.00e+00	974.00
IUUC-Oan-073322	Ornithorhynchus anatinus	78.08	0.00e+00	884.00
IUUC-Ocu-074188	Oryctolagus cuniculus	81.29	0.00e+00	903.00
IUUC-Oba-075436	Oryza barthii	47.09	6.00e-123	434.00
IUUC-Obr-076507	Oryza brachyantha	47.36	9.00e-123	433.00
IUUC-Ogl-077718	Oryza glaberrima	51.25	1.00e-120	426.00
IUUC-Ogu-078349	Oryza glumaepatula	46.91	7.00e-123	434.00
IUUC-Oin-079889	Oryza indica	51.02	6.00e-121	427.00
IUUC-Olo-080521	Oryza longistaminata	47.43	9.00e-123	433.00
IUUC-Ome-081630	Oryza meridionalis	47.23	2.00e-122	432.00
IUUC-Oni-082211	Oryza nivara	47.43	3.00e-123	435.00
IUUC-Opu-083617	Oryza punctata	47.54	6.00e-122	431.00
IUUC-Oru-084252	Oryza rufipogon	47.43	9.00e-123	433.00
IUUC-Osa-085548	Oryza sativa	47.43	9.00e-123	433.00
IUUC-Ola-086366	Oryzias latipes	89.35	0.00e+00	1001.00
IUUC-Olu-087861	Ostreococcus lucimarinus	47.85	2.00e-114	405.00
IUUC-Oga-088003	Otolemur garnettii	83.28	0.00e+00	918.00
IUUC-Oar-089933	Ovis aries	83.80	0.00e+00	919.00
IUUC-Ptr-090718	Pan troglodytes	83.10	0.00e+00	915.00
IUUC-Pan-092526	Papio anubis	83.10	0.00e+00	916.00
IUUC-Psi-094034	Pelodiscus sinensis	84.82	0.00e+00	917.00
IUUC-Pno-095030	Phaeosphaeria nodorum	58.48	2.00e-104	372.00
IUUC-Ppa-095615	Physcomitrella patens	47.13	1.00e-121	430.00
IUUC-Pfo-097050	Poecilia formosa	86.04	0.00e+00	983.00
IUUC-Pab-098519	Pongo abelii	83.10	0.00e+00	915.00
IUUC-Pop-100042	Populus trichocarpa	50.68	3.00e-123	435.00
IUUC-Pca-101104	Procavia capensis	88.75	0.00e+00	692.00
IUUC-Ppe-101642	Prunus persica	46.88	3.00e-120	425.00
IUUC-Pva-102470	Pteropus vampyrus	70.56	0.00e+00	784.00
IUUC-Pgr-103406	Puccinia graminis	61.74	6.00e-92	332.00
IUUC-Ptt-103713	Puccinia triticina	51.05	1.00e-73	271.00
IUUC-Pte-104259	Pyrenophora teres	60.07	4.00e-105	375.00
IUUC-Pyt-104752	Pyrenophora triticirepentis	60.42	9.00e-106	378.00
IUUC-Rno-104960	Rattus norvegicus	70.96	0.00e+00	791.00
IUUC-Sce-106290	Saccharomyces cerevisiae	41.42	2.00e-110	393.00
IUUC-Sha-107603	Sarcophilus harrisii	83.57	0.00e+00	919.00
IUUC-Sja-107772	Schizosaccharomyces japonicus	53.76	1.00e-104	374.00
IUUC-Spo-108202	Schizosaccharomyces pombe	41.54	1.00e-104	374.00
IUUC-Ssl-108535	Sclerotinia sclerotiorum	45.48	2.00e-102	366.00
IUUC-Smo-109309	Selaginella moellendorffii	45.98	5.00e-122	431.00
IUUC-Sit-109745	Setaria italica	47.95	5.00e-122	431.00
IUUC-Sly-110890	Solanum lycopersicum	50.90	1.00e-121	430.00
IUUC-Stu-112144	Solanum tuberosum	45.06	3.00e-113	402.00
IUUC-Sar-113521	Sorex araneus	73.89	0.00e+00	757.00
IUUC-Sbi-114764	Sorghum bicolor	48.36	7.00e-123	434.00
IUUC-Sre-115141	Sporisorium reilianum	66.42	1.00e-110	394.00
IUUC-Ssc-115732	Sus scrofa	83.18	0.00e+00	887.00
IUUC-Tgu-117190	Taeniopygia guttata	84.99	0.00e+00	920.00
IUUC-Tru-118735	Takifugu rubripes	70.36	0.00e+00	779.00
IUUC-Tsy-119503	Tarsius syrichta	67.96	0.00e+00	692.00
IUUC-Tni-119833	Tetraodon nigroviridis	85.84	0.00e+00	966.00
IUUC-Tca-121386	Theobroma cacao	47.66	2.00e-122	432.00
IUUC-Tre-122070	Trichoderma reesei	59.23	7.00e-103	368.00
IUUC-Tvi-122305	Trichoderma virens	60.00	2.00e-101	363.00
IUUC-Tae-123515	Triticum aestivum	47.13	1.00e-121	429.00
IUUC-Tur-126416	Triticum urartu	47.36	3.00e-120	425.00
IUUC-Tme-127174	Tuber melanosporum	51.07	2.00e-67	250.00
IUUC-Tbe-127791	Tupaia belangeri	75.65	3.00e-100	358.00
IUUC-Ttr-129224	Tursiops truncatus	81.49	0.00e+00	908.00
IUUC-Uma-129372	Ustilago maydis	66.42	5.00e-110	392.00
IUUC-Vda-129819	Verticillium dahliae	53.24	7.00e-84	305.00
IUUC-Vpa-130220	Vicugna pacos	69.98	0.00e+00	730.00
IUUC-Vvi-131649	Vitis vinifera	47.27	7.00e-122	431.00
IUUC-Xtr-132954	Xenopus tropicalis	72.22	0.00e+00	798.00
IUUC-Xma-134082	Xiphophorus maculatus	93.43	0.00e+00	894.00
IUUC-Yli-134422	Yarrowia lipolytica	42.26	5.00e-112	398.00
IUUC-Zma-135621	Zea mays	61.99	3.00e-116	412.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence