iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-027647

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin-specific peptidase 14 (tRNA-guanine transglycosylase)

Genbank Nucleotide ID

CABZ01057205

Gene Name

usp14

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000025889.6	ENSDART00000032540.6	ENSDARP00000037906.6

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.50e-65	220.7	105	480
ULD/UDP/UBQ/UBQ_Other	8.80e-08	32.8	6	74

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs.... 85
           +Gl+NlgNtCYmN+++QcL ++pel+ +l + ++ +l+ +  + p++ ++ +l++l e++ +++++++ p  ll+ l+++ ++f     
   Q: 105  CGLTNLGNTCYMNATVQCLRSVPELKGALRR-YSGALRSSGANAPSQYITAALRDLYESM-DKTSSSIPPIILLQFLHMAFPQFAekgd 191
           7***************************999.****************************.99999******************99*** PP
   S: 86   ..gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
             +y qqDa+E++ +++  l+++l+ ++ ++ +e+        + ++     +k+ks+i++ F++++++++kc e + +  ++ +  +l
   Q: 192  qgQYLQQDANECWVQVMRVLQQKLEPQEPETPMET--------DGDSAAAASTKKKSFIDQYFGVEFETSMKCTEAEDEEPTKGTESQL 272
           999*********************55444444444........44457889999**************************998888888 PP
   S: 173  slpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdl 261
           +l+   ++e   + l   L+   +e+  +     ++++ +++    k+ k+++lP +L++++ Rf ++e+++++ k+ k v+fpl+Ld+
   Q: 273  QLSCFINQEV--KYLATGLRLRLQEDITK-----FSPSLQRNALYIKSSKISRLPAYLTVQMVRFFYKEKESVNAKVLKDVKFPLMLDV 354
           8888777754..47888888877776665.....8999999999********************************************* PP
   S: 262  spfcts.......................peekqke.............................kkkYeLiavvvHsG.slssGHYva 297
            + cts                       +     +                             +  YeL av+ H+G s+ssGHYva
   Q: 355  YELCTSelqekmvslrskfkemedkklekQ-----QqsepnkkpgalketkyepfsfpddlgsnnSGYYELQAVLTHQGrSSSSGHYVA 438
           ******777777777777766666655540.....0455566666666666667777777777669*********************** PP
   S: 298  yvknekgkWllfdDskVtevkeeevleetg....staYvlfY 335
           +vk ++++W++fdD+kV++v+ e++l+ +g    + aYvl+Y
   Q: 439  WVKRKEDEWVKFDDDKVSVVTPEDILKLSGggdwHIAYVLLY 480
           ***************************988************ PP

ULD/UDP/UBQ/UBQ_Other

   S: 3    vtvksldgseltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllek 72
           v vk+ + +   +++n  ++  ++K +++ ++g++pe+q+ ++kG  L+dd  +++ +lk+g+t++++ +
   Q: 6    VNVKWGKEKFDAVELNTEEPPMVFKAQLFALTGVQPERQKVMVKGGTLKDD-EWGNIKLKNGMTLLMMGS 74
           779999999889999************************************.***************965 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MPVFTVNVKW GKEKFDAVEL NTEEPPMVFK AQLFALTGVQ PERQKVMVKG GTLKDDEWGN 60
IKLKNGMTLL MMGSADALPE EPVVRPMFVE DMTEEQLASA MELPCGLTNL GNTCYMNATV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAATCGCTCG TCGAGCTCAT CGATCTGGTC ATCATGCAGT TGCAGCGTCA TTGTGGGCTG 60
CCGTTTGAAT GAAGTTAGTA GACACACAAA TCTTCCGCAT CCCATCGTAA ACCCTTTGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR019954--Ubiquitin_CS
IPR000626--Ubiquitin_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00299--UBIQUITIN_1
PS50053--UBIQUITIN_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

SMART

SM00213--UBQ

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000893	Aegilops tauschii	45.05	3.00e-39	156.00
IUUC-Aml-002053	Ailuropoda melanoleuca	82.34	0.00e+00	794.00
IUUC-Atr-002725	Amborella trichopoda	42.48	2.00e-102	366.00
IUUC-Apl-004031	Anas platyrhynchos	83.98	0.00e+00	827.00
IUUC-Aca-004361	Anolis carolinensis	84.32	0.00e+00	849.00
IUUC-Aly-006176	Arabidopsis lyrata	42.94	2.00e-113	402.00
IUUC-Ath-007623	Arabidopsis thaliana	43.03	6.00e-113	401.00
IUUC-Ago-007796	Ashbya gossypii	32.37	6.00e-60	225.00
IUUC-Acl-008258	Aspergillus clavatus	39.18	2.00e-67	249.00
IUUC-Afl-008732	Aspergillus flavus	35.29	6.00e-83	301.00
IUUC-Afu-008755	Aspergillus fumigatus	34.84	8.00e-77	281.00
IUUC-Ani-009148	Aspergillus nidulans	36.68	1.00e-89	324.00
IUUC-Ang-009878	Aspergillus niger	35.86	2.00e-83	303.00
IUUC-Aor-010239	Aspergillus oryzae	35.29	6.00e-83	301.00
IUUC-Ate-010243	Aspergillus terreus	36.15	4.00e-81	295.00
IUUC-Ame-011327	Astyanax mexicanus	56.71	2.00e-136	479.00
IUUC-Bgr-012231	Blumeria graminis	39.80	9.00e-70	258.00
IUUC-Bta-012553	Bos taurus	82.45	0.00e+00	812.00
IUUC-Bci-013606	Botrytis cinerea	41.65	5.00e-73	268.00
IUUC-Bdi-014567	Brachypodium distachyon	42.39	1.00e-112	399.00
IUUC-Bol-015565	Brassica oleracea	41.88	3.00e-113	402.00
IUUC-Bra-017297	Brassica rapa	42.15	4.00e-112	398.00
IUUC-Cel-018140	Caenorhabditis elegans	43.23	2.00e-105	376.00
IUUC-Cja-019516	Callithrix jacchus	81.34	0.00e+00	814.00
IUUC-Cfa-020808	Canis familiaris	82.04	0.00e+00	815.00
IUUC-Cpo-021688	Cavia porcellus	82.00	0.00e+00	806.00
IUUC-Cre-022663	Chlamydomonas reinhardtii	38.51	1.00e-86	313.00
IUUC-Csa-023429	Chlorocebus sabaeus	81.84	0.00e+00	796.00
IUUC-Cho-024347	Choloepus hoffmanni	82.04	0.00e+00	810.00
IUUC-Cin-025198	Ciona intestinalis	54.88	4.00e-152	531.00
IUUC-Csv-026007	Ciona savignyi	54.73	2.00e-155	542.00
IUUC-Cgl-026757	Colletotrichum gloeosporioides	42.16	2.00e-68	253.00
IUUC-Cne-026963	Cryptococcus neoformans	35.74	8.00e-74	271.00
IUUC-Cme-027240	Cyanidioschyzon merolae	32.37	6.00e-67	248.00
IUUC-Dno-029967	Dasypus novemcinctus	81.84	0.00e+00	795.00
IUUC-Dor-030886	Dipodomys ordii	76.38	0.00e+00	638.00
IUUC-Dse-031466	Dothistroma septosporum	37.27	1.00e-59	224.00
IUUC-Dme-032079	Drosophila melanogaster	55.69	2.00e-160	558.00
IUUC-Ete-032351	Echinops telfairi	74.23	0.00e+00	740.00
IUUC-Eca-033461	Equus caballus	82.04	0.00e+00	850.00
IUUC-Eeu-035220	Erinaceus europaeus	63.49	3.00e-170	591.00
IUUC-Fca-036210	Felis catus	82.45	0.00e+00	816.00
IUUC-Fal-037528	Ficedula albicollis	83.81	0.00e+00	805.00
IUUC-Fox-037805	Fusarium oxysporum	40.78	9.00e-74	271.00
IUUC-Fso-038177	Fusarium solani	36.59	8.00e-86	311.00
IUUC-Gmo-038953	Gadus morhua	86.09	0.00e+00	819.00
IUUC-Ggr-039972	Gaeumannomyces graminis	40.72	1.00e-66	247.00
IUUC-Gga-040462	Gallus gallus	83.03	0.00e+00	820.00
IUUC-Gac-041312	Gasterosteus aculeatus	89.53	0.00e+00	862.00
IUUC-Gma-043255	Glycine max	41.94	2.00e-106	379.00
IUUC-Ggo-045458	Gorilla gorilla	69.11	0.00e+00	673.00
IUUC-Hsa-045706	Homo sapiens	82.04	0.00e+00	797.00
IUUC-Hvu-047821	Hordeum vulgare	48.42	2.00e-58	218.00
IUUC-Itr-048654	Ictidomys tridecemlineatus	80.61	0.00e+00	820.00
IUUC-Lch-050464	Latimeria chalumnae	83.78	0.00e+00	838.00
IUUC-Lpe-051419	Leersia perrieri	42.18	5.00e-107	381.00
IUUC-Loc-052732	Lepisosteus oculatus	86.82	0.00e+00	884.00
IUUC-Lma-053177	Leptosphaeria maculans	40.62	9.00e-71	261.00
IUUC-Laf-053822	Loxodonta africana	82.45	0.00e+00	811.00
IUUC-Mcc-055893	Macaca mulatta	82.04	0.00e+00	798.00
IUUC-Meu-056307	Macropus eugenii	74.07	0.00e+00	716.00
IUUC-Mor-057171	Magnaporthe oryzae	36.67	5.00e-85	308.00
IUUC-Mpo-057415	Magnaporthe poae	41.35	3.00e-72	266.00
IUUC-Mtr-057901	Medicago truncatula	42.00	3.00e-110	392.00
IUUC-Mla-058897	Melampsora laricipopulina	36.96	3.00e-84	306.00
IUUC-Mga-060016	Meleagris gallopavo	84.19	0.00e+00	827.00
IUUC-Mvi-060562	Microbotryum violaceum	40.17	6.00e-68	251.00
IUUC-Mmr-060624	Microcebus murinus	82.04	0.00e+00	847.00
IUUC-Mdo-061809	Monodelphis domestica	83.94	0.00e+00	815.00
IUUC-Mmu-063869	Mus musculus	82.04	0.00e+00	811.00
IUUC-Mac-064876	Musa acuminata	40.73	3.00e-99	355.00
IUUC-Mpu-066480	Mustela putorius furo	82.24	0.00e+00	815.00
IUUC-Mlu-067866	Myotis lucifugus	82.04	0.00e+00	823.00
IUUC-Nfi-068393	Neosartorya fischeri	34.14	2.00e-74	273.00
IUUC-Ncr-068815	Neurospora crassa	38.15	1.00e-86	313.00
IUUC-Nle-070121	Nomascus leucogenys	81.82	3.00e-120	424.00
IUUC-Opr-070712	Ochotona princeps	66.04	2.00e-149	522.00
IUUC-Ont-071544	Oreochromis niloticus	89.98	0.00e+00	822.00
IUUC-Oan-073635	Ornithorhynchus anatinus	82.98	0.00e+00	680.00
IUUC-Ocu-074926	Oryctolagus cuniculus	82.00	0.00e+00	800.00
IUUC-Oba-075633	Oryza barthii	42.77	1.00e-107	383.00
IUUC-Obr-076423	Oryza brachyantha	42.89	7.00e-112	397.00
IUUC-Ogl-077913	Oryza glaberrima	42.89	2.00e-111	396.00
IUUC-Ogu-078435	Oryza glumaepatula	42.77	1.00e-107	383.00
IUUC-Oin-080072	Oryza indica	42.71	2.00e-107	383.00
IUUC-Olo-080535	Oryza longistaminata	38.76	6.00e-91	328.00
IUUC-Ome-081309	Oryza meridionalis	42.77	1.00e-107	383.00
IUUC-Oni-083113	Oryza nivara	42.77	1.00e-107	383.00
IUUC-Opu-083168	Oryza punctata	42.03	8.00e-103	367.00
IUUC-Oru-084253	Oryza rufipogon	42.77	1.00e-107	383.00
IUUC-Osa-085554	Oryza sativa	42.89	1.00e-111	396.00
IUUC-Ola-086998	Oryzias latipes	90.02	0.00e+00	858.00
IUUC-Olu-087818	Ostreococcus lucimarinus	36.79	4.00e-71	261.00
IUUC-Oga-088571	Otolemur garnettii	81.80	0.00e+00	814.00
IUUC-Oar-089526	Ovis aries	82.79	0.00e+00	810.00
IUUC-Ptr-091433	Pan troglodytes	82.04	0.00e+00	798.00
IUUC-Pan-091966	Papio anubis	81.84	0.00e+00	796.00
IUUC-Psi-093458	Pelodiscus sinensis	83.37	0.00e+00	795.00
IUUC-Pma-094343	Petromyzon marinus	68.62	6.00e-120	423.00
IUUC-Pno-095109	Phaeosphaeria nodorum	39.50	9.00e-67	248.00
IUUC-Ppa-095756	Physcomitrella patens	42.66	8.00e-112	397.00
IUUC-Pfo-096514	Poecilia formosa	90.18	0.00e+00	841.00
IUUC-Pab-098477	Pongo abelii	71.95	2.00e-180	625.00
IUUC-Pop-099221	Populus trichocarpa	42.37	5.00e-104	371.00
IUUC-Pca-100791	Procavia capensis	68.78	3.00e-152	531.00
IUUC-Ppe-101812	Prunus persica	42.54	5.00e-110	391.00
IUUC-Pva-102462	Pteropus vampyrus	78.59	0.00e+00	659.00
IUUC-Pgr-103623	Puccinia graminis	41.95	7.00e-77	281.00
IUUC-Ptt-103767	Puccinia triticina	40.42	1.00e-69	257.00
IUUC-Pte-104109	Pyrenophora teres	40.55	6.00e-72	265.00
IUUC-Pyt-104766	Pyrenophora triticirepentis	40.97	2.00e-70	260.00
IUUC-Rno-105351	Rattus norvegicus	80.82	0.00e+00	785.00
IUUC-Sce-106168	Saccharomyces cerevisiae	33.20	2.00e-61	229.00
IUUC-Sha-107491	Sarcophilus harrisii	84.32	0.00e+00	829.00
IUUC-Sja-107769	Schizosaccharomyces japonicus	35.79	8.00e-82	297.00
IUUC-Spo-108174	Schizosaccharomyces pombe	38.10	3.00e-79	289.00
IUUC-Ssl-108659	Sclerotinia sclerotiorum	40.89	3.00e-72	266.00
IUUC-Smo-108805	Selaginella moellendorffii	44.15	4.00e-113	401.00
IUUC-Sit-110361	Setaria italica	43.23	2.00e-115	409.00
IUUC-Sly-110965	Solanum lycopersicum	41.25	6.00e-110	390.00
IUUC-Sar-113355	Sorex araneus	83.39	6.00e-143	500.00
IUUC-Sbi-114778	Sorghum bicolor	43.12	5.00e-111	394.00
IUUC-Sre-115011	Sporisorium reilianum	37.85	7.00e-62	231.00
IUUC-Ssc-116273	Sus scrofa	81.76	0.00e+00	798.00
IUUC-Tgu-117063	Taeniopygia guttata	84.12	0.00e+00	805.00
IUUC-Tru-118381	Takifugu rubripes	87.20	0.00e+00	865.00
IUUC-Tsy-119076	Tarsius syrichta	68.27	3.00e-97	348.00
IUUC-Tni-119941	Tetraodon nigroviridis	87.53	0.00e+00	838.00
IUUC-Tca-121246	Theobroma cacao	42.32	4.00e-111	395.00
IUUC-Tre-121969	Trichoderma reesei	40.15	8.00e-71	261.00
IUUC-Tvi-122543	Trichoderma virens	36.16	7.00e-82	298.00
IUUC-Tae-125484	Triticum aestivum	43.29	2.00e-110	392.00
IUUC-Tur-126128	Triticum urartu	42.36	5.00e-40	159.00
IUUC-Tbe-128030	Tupaia belangeri	75.83	0.00e+00	718.00
IUUC-Ttr-128701	Tursiops truncatus	80.95	0.00e+00	662.00
IUUC-Uma-129657	Ustilago maydis	38.14	5.00e-66	245.00
IUUC-Vda-129723	Verticillium dahliae	38.46	1.00e-62	234.00
IUUC-Vpa-130284	Vicugna pacos	58.88	4.00e-152	531.00
IUUC-Vvi-131037	Vitis vinifera	43.43	6.00e-112	397.00
IUUC-Xtr-132235	Xenopus tropicalis	82.17	0.00e+00	845.00
IUUC-Xma-133840	Xiphophorus maculatus	90.18	0.00e+00	869.00
IUUC-Yli-134453	Yarrowia lipolytica	39.24	3.00e-88	319.00
IUUC-Zma-135669	Zea mays	36.28	4.00e-95	342.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence