iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093458

Ensembl Protein ID

ENSPSIP00000008680.1

UniProt Accession

K7FKX0; K7FKX0_PELSI

Genbank Protein ID

ENSPSIP00000008680

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01201499

Gene Name

USP14

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000007936.1	ENSPSIT00000008726.1	ENSPSIP00000008680.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.40e-63	214.4	79	452
ULD/UDP/UBQ/UBQ_Other	2.00e-06	27.6	2	48

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs.... 85
           +Gl+NlgNtCYmN+++Qc+ ++pel+e+l++ +  +l+++ +  + + ++ +l++lfe++ +++++++ p  ll+ l+++ ++f     
   Q: 79   CGLTNLGNTCYMNATVQCIRSVPELKEALKK-YGGALRASGEMASAQYITAALRDLFESM-DKTSSSIPPIILLQFLHMAFPQFAekgd 165
           7******************************.****************************.99999******************99*** PP
   S: 86   ..gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
             +y qqDa+E++ +++  l+++l         e  e d    +d+      +k+ksl+++ F +++++++kc e + + +++ + ++l
   Q: 166  qgQYLQQDANECWVQMMRVLQQKL---------EGVEGDALMETDSGATAAASKKKSLVDQFFSIEFETTMKCTEAEDEEVTKGKENQL 245
           999*********************.........4455666666677889999************************9999998888888 PP
   S: 173  slpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdl 261
           +l+   ++e   + l   L+   +ee  +      +++ +++    k+ k+++lP +L++++ Rf ++e+++++ k+ k v+fpl+Ld+
   Q: 246  QLSCFINQEV--KYLFTGLKLRLQEEITK-----LSPTLQRNAVHIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDV 327
           8888877754..58999999999998887.....68999999999******************************************** PP
   S: 262  spfcts........................peekqke...........................kkkYeLiavvvHsG.slssGHYvay 298
            + ct                         p     +                           +  Y+L av+ H+G s+ssGHYv++
   Q: 328  YELCTPelqekmvpfrskfkdledkkinqqP-----KnsnkgdgaqkevkyepfsfpedigsnnCGFYDLQAVLTHQGrSSSSGHYVSW 411
           ******6666666666666666666655550.....0455555666666666666666666666************************* PP
   S: 299  vknekgkWllfdDskVtevkeeevleetg....staYvlfY 335
           vk ++++W++fdD+kV+ v+ e++l+ +g    + aYvl+Y
   Q: 412  VKRKQDEWIKFDDDKVSIVTPEDILRLSGggdwHIAYVLLY 452
           **************************988************ PP

ULD/UDP/UBQ/UBQ_Other

   S: 25   eLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllek 72
           ++K +++ ++g++p++q+ ++kG  L+dd  +++ ++k+g+t++++ +
   Q: 2    VFKAQLFALTGVQPDRQKVVVKGGALKDD-EWGNIKIKNGMTLLMMGS 48
           689**************************.***************965 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MVFKAQLFAL TGVQPDRQKV VVKGGALKDD EWGNIKIKNG MTLLMMGSAD ALPEEPVARP 60
VFVEDMTEEQ LASAMELPCG LTNLGNTCYM NATVQCIRSV PELKEALKKY GGALRASGEM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGAATGTAAA ATGGGGGAAA GAGAAATTTG ATGGTGTAGA GCTGAATACT GATGAACCTC 60
CAATGGTGTT CAAGGCTCAG CTTTTTGCAT TGACTGGAGT TCAGCCAGAT AGGCAGAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR019954--Ubiquitin_CS
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00299--UBIQUITIN_1
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0009986--C:cell surface
GO:0031410--C:cytoplasmic vesicle
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0045202--C:synapse
GO:0004866--F:endopeptidase inhibitor activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0007268--P:chemical synaptic transmission
GO:1903070--P:negative regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:0016579--P:protein deubiquitination
GO:0050920--P:regulation of chemotaxis
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000893	Aegilops tauschii	31.25	2.00e-35	143.00
IUUC-Aml-002053	Ailuropoda melanoleuca	88.79	0.00e+00	813.00
IUUC-Atr-002725	Amborella trichopoda	41.45	5.00e-92	331.00
IUUC-Apl-004031	Anas platyrhynchos	92.86	0.00e+00	869.00
IUUC-Aca-004361	Anolis carolinensis	90.97	0.00e+00	880.00
IUUC-Aly-006176	Arabidopsis lyrata	41.49	3.00e-103	368.00
IUUC-Ath-007658	Arabidopsis thaliana	41.06	7.00e-102	364.00
IUUC-Ago-007796	Ashbya gossypii	32.71	4.00e-59	221.00
IUUC-Acl-008258	Aspergillus clavatus	38.20	3.00e-66	245.00
IUUC-Afl-008732	Aspergillus flavus	34.73	1.00e-81	296.00
IUUC-Afu-008755	Aspergillus fumigatus	36.46	1.00e-83	303.00
IUUC-Ani-009148	Aspergillus nidulans	40.05	1.00e-69	257.00
IUUC-Ang-009878	Aspergillus niger	34.95	8.00e-71	261.00
IUUC-Aor-010239	Aspergillus oryzae	34.73	1.00e-81	296.00
IUUC-Ate-010243	Aspergillus terreus	36.45	4.00e-81	295.00
IUUC-Ame-011327	Astyanax mexicanus	49.36	4.00e-111	394.00
IUUC-Bgr-012231	Blumeria graminis	34.61	3.00e-77	282.00
IUUC-Bta-012553	Bos taurus	88.58	0.00e+00	821.00
IUUC-Bci-013606	Botrytis cinerea	41.39	4.00e-70	258.00
IUUC-Bdi-014567	Brachypodium distachyon	41.42	9.00e-104	370.00
IUUC-Bol-015565	Brassica oleracea	41.61	2.00e-104	372.00
IUUC-Bra-017297	Brassica rapa	41.56	2.00e-103	369.00
IUUC-Cel-018140	Caenorhabditis elegans	41.15	5.00e-95	341.00
IUUC-Cja-019516	Callithrix jacchus	88.22	0.00e+00	829.00
IUUC-Cfa-020808	Canis familiaris	89.44	0.00e+00	830.00
IUUC-Cpo-021688	Cavia porcellus	88.60	0.00e+00	820.00
IUUC-Cre-022663	Chlamydomonas reinhardtii	38.46	2.00e-75	275.00
IUUC-Csa-023429	Chlorocebus sabaeus	88.36	0.00e+00	810.00
IUUC-Cho-024347	Choloepus hoffmanni	88.79	0.00e+00	825.00
IUUC-Cin-025198	Ciona intestinalis	53.94	6.00e-142	497.00
IUUC-Csv-026007	Ciona savignyi	53.30	1.00e-141	496.00
IUUC-Cgl-026757	Colletotrichum gloeosporioides	40.67	5.00e-64	238.00
IUUC-Cne-026963	Cryptococcus neoformans	34.89	3.00e-77	281.00
IUUC-Cme-027240	Cyanidioschyzon merolae	34.02	2.00e-56	213.00
IUUC-Dre-027647	Danio rerio	83.37	0.00e+00	795.00
IUUC-Dno-029967	Dasypus novemcinctus	88.36	0.00e+00	811.00
IUUC-Dor-030886	Dipodomys ordii	82.80	0.00e+00	699.00
IUUC-Dse-031466	Dothistroma septosporum	36.46	2.00e-57	216.00
IUUC-Dme-032079	Drosophila melanogaster	55.02	1.00e-149	522.00
IUUC-Ete-032351	Echinops telfairi	80.09	0.00e+00	750.00
IUUC-Eca-033461	Equus caballus	88.58	0.00e+00	867.00
IUUC-Eeu-035220	Erinaceus europaeus	66.81	3.00e-172	597.00
IUUC-Fca-036210	Felis catus	89.66	0.00e+00	831.00
IUUC-Fal-037528	Ficedula albicollis	93.29	0.00e+00	852.00
IUUC-Fox-037805	Fusarium oxysporum	41.34	3.00e-70	258.00
IUUC-Fso-038177	Fusarium solani	40.33	9.00e-67	247.00
IUUC-Gmo-038953	Gadus morhua	79.27	0.00e+00	726.00
IUUC-Ggr-039972	Gaeumannomyces graminis	35.81	2.00e-75	276.00
IUUC-Gga-040462	Gallus gallus	91.56	0.00e+00	855.00
IUUC-Gac-041312	Gasterosteus aculeatus	80.22	0.00e+00	762.00
IUUC-Gma-043255	Glycine max	42.07	1.00e-100	359.00
IUUC-Ggo-045458	Gorilla gorilla	73.56	0.00e+00	670.00
IUUC-Hsa-045706	Homo sapiens	88.58	0.00e+00	811.00
IUUC-Hvu-047821	Hordeum vulgare	47.37	7.00e-49	186.00
IUUC-Itr-048654	Ictidomys tridecemlineatus	86.85	0.00e+00	831.00
IUUC-Lch-050464	Latimeria chalumnae	83.91	0.00e+00	785.00
IUUC-Lpe-051419	Leersia perrieri	39.96	2.00e-97	349.00
IUUC-Loc-052732	Lepisosteus oculatus	82.62	0.00e+00	811.00
IUUC-Lma-053177	Leptosphaeria maculans	40.61	8.00e-68	251.00
IUUC-Laf-053822	Loxodonta africana	89.66	0.00e+00	828.00
IUUC-Mcc-055893	Macaca mulatta	88.58	0.00e+00	811.00
IUUC-Meu-056307	Macropus eugenii	78.33	0.00e+00	729.00
IUUC-Mor-057171	Magnaporthe oryzae	39.68	1.00e-65	243.00
IUUC-Mpo-057415	Magnaporthe poae	43.21	2.00e-71	263.00
IUUC-Mtr-057901	Medicago truncatula	41.49	6.00e-101	361.00
IUUC-Mla-058897	Melampsora laricipopulina	40.79	2.00e-71	263.00
IUUC-Mga-060016	Meleagris gallopavo	93.07	0.00e+00	870.00
IUUC-Mvi-060562	Microbotryum violaceum	40.69	5.00e-65	241.00
IUUC-Mmr-060624	Microcebus murinus	88.58	0.00e+00	865.00
IUUC-Mdo-061809	Monodelphis domestica	90.77	0.00e+00	830.00
IUUC-Mmu-063869	Mus musculus	87.93	0.00e+00	814.00
IUUC-Mac-064876	Musa acuminata	38.64	1.00e-87	317.00
IUUC-Mpu-066480	Mustela putorius furo	89.44	0.00e+00	830.00
IUUC-Mlu-067866	Myotis lucifugus	88.15	0.00e+00	833.00
IUUC-Nfi-068393	Neosartorya fischeri	35.20	3.00e-76	279.00
IUUC-Ncr-068815	Neurospora crassa	35.83	2.00e-79	289.00
IUUC-Nle-070121	Nomascus leucogenys	87.22	2.00e-112	397.00
IUUC-Opr-070712	Ochotona princeps	71.70	5.00e-161	560.00
IUUC-Ont-071544	Oreochromis niloticus	81.51	0.00e+00	726.00
IUUC-Oan-073635	Ornithorhynchus anatinus	91.49	0.00e+00	750.00
IUUC-Ocu-074926	Oryctolagus cuniculus	88.34	0.00e+00	806.00
IUUC-Oba-075633	Oryza barthii	40.83	9.00e-97	347.00
IUUC-Obr-076423	Oryza brachyantha	40.21	8.00e-100	357.00
IUUC-Ogl-077913	Oryza glaberrima	40.43	6.00e-100	357.00
IUUC-Ogu-078435	Oryza glumaepatula	40.83	9.00e-97	347.00
IUUC-Oin-080072	Oryza indica	40.83	8.00e-97	347.00
IUUC-Olo-080535	Oryza longistaminata	37.00	5.00e-82	297.00
IUUC-Ome-081309	Oryza meridionalis	40.83	9.00e-97	347.00
IUUC-Oni-083113	Oryza nivara	40.83	9.00e-97	347.00
IUUC-Opu-083168	Oryza punctata	40.04	7.00e-92	330.00
IUUC-Oru-084253	Oryza rufipogon	40.83	9.00e-97	347.00
IUUC-Osa-085554	Oryza sativa	40.43	4.00e-100	358.00
IUUC-Ola-086998	Oryzias latipes	80.09	0.00e+00	749.00
IUUC-Olu-087818	Ostreococcus lucimarinus	37.50	2.00e-68	252.00
IUUC-Oga-088571	Otolemur garnettii	89.42	0.00e+00	829.00
IUUC-Oar-089526	Ovis aries	88.79	0.00e+00	823.00
IUUC-Ptr-091433	Pan troglodytes	88.58	0.00e+00	811.00
IUUC-Pan-091966	Papio anubis	88.36	0.00e+00	810.00
IUUC-Pma-094343	Petromyzon marinus	66.79	5.00e-107	380.00
IUUC-Pno-095109	Phaeosphaeria nodorum	39.52	2.00e-65	243.00
IUUC-Ppa-095756	Physcomitrella patens	42.44	1.00e-103	370.00
IUUC-Pfo-096514	Poecilia formosa	81.94	0.00e+00	743.00
IUUC-Pab-098477	Pongo abelii	77.52	0.00e+00	676.00
IUUC-Pop-099221	Populus trichocarpa	40.34	1.00e-94	339.00
IUUC-Pca-100791	Procavia capensis	73.18	4.00e-162	563.00
IUUC-Ppe-101812	Prunus persica	41.03	3.00e-99	355.00
IUUC-Pva-102462	Pteropus vampyrus	84.94	0.00e+00	711.00
IUUC-Pgr-103623	Puccinia graminis	41.49	5.00e-70	258.00
IUUC-Ptt-103767	Puccinia triticina	39.64	9.00e-69	254.00
IUUC-Pte-104109	Pyrenophora teres	39.57	4.00e-69	255.00
IUUC-Pyt-104766	Pyrenophora triticirepentis	39.84	4.00e-69	255.00
IUUC-Rno-105351	Rattus norvegicus	86.85	0.00e+00	786.00
IUUC-Sce-106168	Saccharomyces cerevisiae	32.99	1.00e-60	226.00
IUUC-Sha-107491	Sarcophilus harrisii	90.32	0.00e+00	841.00
IUUC-Sja-107769	Schizosaccharomyces japonicus	35.85	2.00e-78	286.00
IUUC-Spo-108174	Schizosaccharomyces pombe	38.41	5.00e-78	284.00
IUUC-Ssl-108659	Sclerotinia sclerotiorum	36.04	5.00e-84	305.00
IUUC-Smo-108805	Selaginella moellendorffii	43.76	4.00e-101	361.00
IUUC-Sit-110361	Setaria italica	41.95	1.00e-104	373.00
IUUC-Sly-110965	Solanum lycopersicum	41.56	3.00e-100	358.00
IUUC-Sar-113355	Sorex araneus	78.01	2.00e-179	621.00
IUUC-Sbi-114778	Sorghum bicolor	42.83	2.00e-103	368.00
IUUC-Sre-115011	Sporisorium reilianum	38.05	1.00e-60	227.00
IUUC-Ssc-116273	Sus scrofa	88.58	0.00e+00	815.00
IUUC-Tgu-117063	Taeniopygia guttata	93.07	0.00e+00	853.00
IUUC-Tru-118381	Takifugu rubripes	80.51	0.00e+00	753.00
IUUC-Tsy-119076	Tarsius syrichta	73.52	7.00e-108	383.00
IUUC-Tni-119941	Tetraodon nigroviridis	81.43	0.00e+00	747.00
IUUC-Tca-121246	Theobroma cacao	41.35	2.00e-100	359.00
IUUC-Tre-121969	Trichoderma reesei	38.61	2.00e-64	239.00
IUUC-Tvi-122543	Trichoderma virens	33.21	1.00e-65	244.00
IUUC-Tae-125484	Triticum aestivum	42.18	3.00e-101	361.00
IUUC-Tur-126128	Triticum urartu	33.86	2.00e-38	152.00
IUUC-Tbe-128030	Tupaia belangeri	81.90	0.00e+00	738.00
IUUC-Ttr-128701	Tursiops truncatus	87.62	0.00e+00	711.00
IUUC-Uma-129657	Ustilago maydis	38.24	6.00e-65	241.00
IUUC-Vda-129723	Verticillium dahliae	34.55	3.00e-72	265.00
IUUC-Vpa-130284	Vicugna pacos	62.61	3.00e-156	544.00
IUUC-Vvi-131037	Vitis vinifera	42.68	9.00e-103	367.00
IUUC-Xtr-132235	Xenopus tropicalis	85.56	0.00e+00	836.00
IUUC-Xma-133840	Xiphophorus maculatus	81.94	0.00e+00	768.00
IUUC-Yli-134453	Yarrowia lipolytica	37.61	1.00e-81	296.00
IUUC-Zma-135669	Zea mays	36.15	9.00e-86	310.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence