iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033354

Ensembl Protein ID

ENSECAP00000014451.1

UniProt Accession

F6XH43; F6XH43_HORSE

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000016853.1	ENSECAT00000017768.1	ENSECAP00000014451.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.90e-29	98.4	167	202
UBD/Beta-Prp	7.90e-47	160.0	120	404

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 4    dsvtclaf.sdtllvsGsdDgtikvWDlrtgvllks 38
           +++tcl f s+++l++G++Dg +k+W++   ++l+s
   Q: 167  AGITCLIFdSGGRLITGGRDGCLKIWSYNNEHCLHS 202
           57******766****************999999876 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgti.kvwdvttgkllrsl..sgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk.. 91
           +hk+++ c  + +  s+ ++++  +++ k+w ++tg ll+++    ++a++t++ f++ g  l+tg++D+ +k+w++++  c+h+lk  
   Q: 120  SHKEPVGCCWY-NPASWQVVSCSEASVsKIWHFETGRLLSEFteAHDNAGITCLIFDSGG-RLITGGRDGCLKIWSYNNEHCLHSLKhg 206
           78999997777.5555566666666666**************84455678*********9.9*************************87 PP
   S: 92   ghedsvlslsfsp..sgdklvsGshdrtirv...........wdletgqclee.....tlsghdgvvncvvvhpdgnllvsGslDrtvr 162
           +++++v++++  +  +++ +++ ++dr i+v           w+ +            +  gh++ + cv+  p  +ll+++s+D+ + 
   Q: 207  NEQSEVCDCTCLElnQNKCIIAVGWDRRINVyfgtahdfhhfWKPQ------PhwqddLSHGHKEDILCVAQCP-PFLLATSSYDGEII 288
           77889**9999998555999999********666664444444333......255555*******999987666.6************* PP
   S: 163  lWdlktgkllrtl...........tgghtdsvyslsfdsng........kelvsgsldgtvklwdlqtgec...vrtlnghtdnvksvr 229
           +W++ +g +  +l           ++g ++sv +lsf +++          +v+ +  g+v++w l+ g c     t    +++v+s+ 
   Q: 289  IWNVISGHIYCKLntsspsddpedKEGPERSVSCLSFLRTRanldstsaSLVVASGPRGSVTFWRLSGGACpiaNFTPSRDKAWVSSMV 377
           ****99999999999999999999666999999999777777777777777888889**************9444455556699***** PP
   S: 230  fspnderlvsgs.sDgsiriWdlrsgdl 256
           ++  ++ l++++ ++  +r+++++   l
   Q: 378  VT-AGDALACVAdQESFVRVYNIKEYSL 404
           **.55555555549999*****998765 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

KRRNLLLTGG LDRIIRVWNP YLPRKPTGML KSHTAPVSYI QVSAEDNKIF STSTDNAVKI 60
WDLETDSSLF TVSSKASGLK GELAACLYLP GPRALWVASD TAVLLHLRLR SPPEPHLVLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGAGAAGGA ACTTGCTGCT GACAGGTGGA CTGGATCGAA TAATTAGAGT GTGGAATCCT 60
TATCTGCCAA GGTAAGTTTT CTTTCTCTCT CCAAGAGTGC CATTGATCTC GTAAGGTGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001921	Ailuropoda melanoleuca	79.37	0.00e+00	805.00
IUUC-Ame-011582	Astyanax mexicanus	46.15	3.00e-127	449.00
IUUC-Bta-013034	Bos taurus	76.44	0.00e+00	736.00
IUUC-Cin-025633	Ciona intestinalis	44.94	5.00e-91	327.00
IUUC-Csv-026326	Ciona savignyi	42.11	5.00e-119	421.00
IUUC-Dre-027573	Danio rerio	47.11	2.00e-144	506.00
IUUC-Dno-030073	Dasypus novemcinctus	69.25	0.00e+00	682.00
IUUC-Dme-031984	Drosophila melanogaster	26.32	1.00e-24	108.00
IUUC-Fca-036185	Felis catus	73.41	0.00e+00	728.00
IUUC-Gmo-039551	Gadus morhua	49.35	3.00e-81	295.00
IUUC-Gac-041482	Gasterosteus aculeatus	45.27	3.00e-127	448.00
IUUC-Itr-049019	Ictidomys tridecemlineatus	77.60	0.00e+00	763.00
IUUC-Lch-050242	Latimeria chalumnae	56.15	6.00e-168	583.00
IUUC-Loc-052710	Lepisosteus oculatus	53.32	7.00e-163	567.00
IUUC-Mdo-062347	Monodelphis domestica	63.39	0.00e+00	661.00
IUUC-Mmu-063878	Mus musculus	70.38	0.00e+00	733.00
IUUC-Mpu-065721	Mustela putorius furo	75.85	1.00e-93	335.00
IUUC-Ont-071688	Oreochromis niloticus	44.67	7.00e-125	440.00
IUUC-Oan-072752	Ornithorhynchus anatinus	59.41	1.00e-150	526.00
IUUC-Ocu-074780	Oryctolagus cuniculus	62.99	7.00e-95	339.00
IUUC-Ola-086449	Oryzias latipes	42.32	5.00e-107	381.00
IUUC-Psi-094057	Pelodiscus sinensis	45.66	1.00e-46	180.00
IUUC-Pma-094599	Petromyzon marinus	48.46	6.00e-140	490.00
IUUC-Pfo-096408	Poecilia formosa	43.57	1.00e-126	446.00
IUUC-Ppe-101450	Prunus persica	24.66	2.00e-14	73.90
IUUC-Rno-105331	Rattus norvegicus	65.54	0.00e+00	662.00
IUUC-Sha-106832	Sarcophilus harrisii	65.07	0.00e+00	644.00
IUUC-Smo-109247	Selaginella moellendorffii	27.05	5.00e-43	169.00
IUUC-Ssc-116310	Sus scrofa	76.54	0.00e+00	759.00
IUUC-Tru-117666	Takifugu rubripes	43.34	1.00e-120	426.00
IUUC-Tni-120449	Tetraodon nigroviridis	22.94	1.00e-19	90.50

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence