iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-050242

Ensembl Protein ID

ENSLACP00000008802.1

UniProt Accession

H3AGN1; H3AGN1_LATCH

Genbank Protein ID

ENSLACP00000008802

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01199297

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000007777.1	ENSLACT00000008871.1	ENSLACP00000008802.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.90e-41	138.5	317	353
UBD/Beta-Prp	2.90e-49	168.1	270	605

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 4    dsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           + +tc+ f ++ ++lv+G++Dg +k+W++  g++l++
   Q: 317  SAITCITFdDSgRRLVTGGRDGCLKIWNYNNGRCLRT 353
           56******844599********************985 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheae..vtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk.. 91
           +h k+++   k+ ++ +++++ s+ + +kvwd++tg  + ++sg  +   +t+++f+++g  lvtg++D+ +k+w++++g c++tlk  
   Q: 270  SH-KEPVLRCKYNKEFRHVISCSEGSAVKVWDFETGRQVFEFSGAHGNsaITCITFDDSGRRLVTGGRDGCLKIWNYNNGRCLRTLKke 357
           44.45555589999************************999977554333*************************************99 PP
   S: 92   ghedsvlslsfsp.sg.dklvsGshdrtirvwdletgqclee..........tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlkt 168
           g+ d+++++++ + ++ +++ + ++dr i+++    +   +           ++ gh++ + c++       l+++s+D+ + +W+l +
   Q: 358  GNCDEICDCAYVEvNKnKYIMAVGWDRKINIFSDLVDDLHHIqkplpywqddLKHGHKEDILCIAQCA-PTFLATSSYDGEIIVWNLVS 445
           9************955599************765555554445677788888******9999986443.599***************99 PP
   S: 169  gkllrtl.....tgghtdsvysls.......fdsng.......kelvsgsldgtvklwdlq.tgecvrtlnght..dnvksvrfspnde 235
           g +  +l     + + td   s++       f +++         lvs +  g++++w+l   g+   t+ + +  ++++ + ++ +d+
   Q: 446  GHMYCQLqtpppS-NCTDGYVSVDmsvtkvvFLKTRalksestAPLVSSGPQGSINFWNLLnGGQLFATFVASRinSQISTITVTAEDT 533
           9999999777752.3444444444444444444444666666799**************9956778999999877799*********** PP
   S: 236  rlvsgssDgsiriWdlrsgdllktlqlhn......ssvisvav.............lsfgdnvlvlgsedskvniwkl 294
           +l+ + + g i+++d+ +  + + ++ +       +                    l  ++++l++ s d++v++w+l
   Q: 534  FLYIADHAGYIYVYDINNYSTSGPVKDPPkvwttvT------NywrahintitsleLIDEHKILLTSSTDCTVRLWSL 605
           ***************************996666662......144433354433222334999999999*******98 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MIQLQGCVNI LILTSVGETL RTWKKLPKAE NLPTIGIESA VLSPKVMFIR WKVHEDWVTQ 60
LKYYDSIRAV ISASNHESTA LVIDSISERF KNQGCTVGTT NVEQQLKEIK DYGKEGKGKR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGATACAGC TTCAAGTGTG ATTGTACAGC AGACAACGCT GCACATGGGC TATTGACATT 60
CTTTTTTTTA ATTTTATAGG GCTGTGTGAA CATTTTGATT CTTACTTCTG TAGGTGAAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001921	Ailuropoda melanoleuca	60.74	0.00e+00	661.00
IUUC-Ame-011582	Astyanax mexicanus	55.01	0.00e+00	746.00
IUUC-Bta-013034	Bos taurus	58.15	2.00e-176	612.00
IUUC-Cin-025633	Ciona intestinalis	46.49	2.00e-104	372.00
IUUC-Csv-026326	Ciona savignyi	46.48	1.00e-136	479.00
IUUC-Dre-027573	Danio rerio	53.61	0.00e+00	734.00
IUUC-Dno-030073	Dasypus novemcinctus	57.07	0.00e+00	754.00
IUUC-Dme-031984	Drosophila melanogaster	26.77	2.00e-49	191.00
IUUC-Eca-033354	Equus caballus	56.15	3.00e-173	601.00
IUUC-Fca-036185	Felis catus	57.74	2.00e-170	591.00
IUUC-Gmo-039551	Gadus morhua	58.28	1.00e-108	386.00
IUUC-Gac-041482	Gasterosteus aculeatus	54.15	6.00e-168	583.00
IUUC-Itr-049019	Ictidomys tridecemlineatus	60.12	0.00e+00	652.00
IUUC-Loc-052710	Lepisosteus oculatus	67.59	0.00e+00	936.00
IUUC-Mdo-062347	Monodelphis domestica	61.73	0.00e+00	863.00
IUUC-Mmu-063878	Mus musculus	58.02	0.00e+00	826.00
IUUC-Mpu-065721	Mustela putorius furo	54.68	4.00e-66	243.00
IUUC-Ont-071688	Oreochromis niloticus	55.36	1.00e-167	582.00
IUUC-Oan-072752	Ornithorhynchus anatinus	57.26	7.00e-163	566.00
IUUC-Ocu-074780	Oryctolagus cuniculus	47.18	3.00e-70	258.00
IUUC-Ola-086449	Oryzias latipes	51.07	2.00e-139	488.00
IUUC-Pma-094599	Petromyzon marinus	54.58	2.00e-174	605.00
IUUC-Pfo-096408	Poecilia formosa	48.84	0.00e+00	682.00
IUUC-Rno-105331	Rattus norvegicus	54.76	2.00e-166	578.00
IUUC-Sha-106832	Sarcophilus harrisii	62.13	0.00e+00	675.00
IUUC-Smo-109247	Selaginella moellendorffii	28.60	2.00e-52	201.00
IUUC-Ssc-116310	Sus scrofa	59.13	2.00e-176	611.00
IUUC-Tru-117666	Takifugu rubripes	53.15	2.00e-155	542.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence