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Tag Content
UUCD2 ID IUUC-Mlu-067036
UUCD1 version UUC-MyL-00571
Ensembl Protein ID ENSMLUP00000011106.2
UniProt Accession G1PK07; G1PK07_MYOLU
Genbank Protein ID ENSMLUP00000011106
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAPE02041020
Gene Name CUL7
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMLUG00000012163.2 ENSMLUT00000012190.2 ENSMLUP00000011106.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/Cullin 1.10e-142 476.9 1056 1606
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/Cullin
   S: 70   nreWekfreqlkvlrkifayldrtyvkkskkvsevrkLaldlwrkeivedikkrllelllklieaeRkgeavdrrllsgvveslveL 156
            ++W+ freql++++++f      y+++           +++w+++i+ed +krll+l+++l+ a+R+++++++r+l++++++    
   Q: 1056 PTFWPVFREQLCRHTRLF------YMVR-----------AQAWSQDIAED-RKRLLHLSSRLNGALRQEQNFADRFLPDDEAA---- 1120
           689***************......****...........***********.********************************.... PP
   S: 157  slnklaiykesFEakfleatqefykaesaeflqe.nevdeYlkkvearlneeeeraaryleestetkLlevvekeliakhlesllae 242
               +a++k+++Ea++++ +q+++ ++++ ++   + +d+Yl+++ea+ n+++++aa++++++++t+Ll++ve+++++         
   Q: 1121 ----QALGKTCWEALVSPLVQNITCPDEDGVSPLgWLLDQYLQCREAAHNPQSRAAAFSSRVRRLTHLLVHVEPCEVP--------A 1195
           ....*************************************************************************9........7 PP
   S: 243  lvallrdkktedlsrmykLlsrvln..gleellkeleshikeqgkaaltaeekekdpkkyVerllelknklqklvseaFnndakFlk 327
                r +++++ +++ +L++ +l+  ++++l++++++ ++eq++ +lt++++++d   +V+r++e++n lqk++se+F+++a+Fl 
   Q: 1196 AAGARRPNGRNRSHDWGSLATPGLPssIVKNLTRCWQAAVEEQVNSFLTSHWRDDD---FVPRYCEHFNNLQKSSSELFGPRAAFLL 1279
           78899*******************999*****************************...**************************** PP
   S: 328  aldkafetfvnknsvlkaakspEllAryiDqlLrks.skglteeeleaqldkvllvfkyisekdv...FekyYkkhLakRLlsgksa 410
           al+++++ +++k ++l+aa+++E++Ar+iDq++++s ++g++++e++a+l+++l+ + ++s++++   Fe+yY++++a+RLls    
   Q: 1280 ALQNGCAGALLKLPFLQAAHVSEQFARHIDQRIQGSrIGGARGMEMLAHLQRCLETVLIFSGLEIattFEHYYQHYMADRLLS--LG 1364
           ***********************************************************************************..** PP
   S: 411  sseaEesviekLkeecgaeftskL.erMfqdlkvSedlnrqFk............................................ 452
           ss++E++v+e++    g++f+++L ++M++ l++Se+l+rqF+                                            
   Q: 1365 SSWLEGAVLEQI----GPCFPHRLpQQMLRTLSTSEELQRQFHvyqlqrldqellkledtekkiqvgasqetsgkehvgerqeeaee 1447
           ************....*********************************************************************** PP
   S: 453  ...............eekenteesesvelsvlvLsagaWpta..set..ekvsLPaelektiekfeefY........lekhsgRkLq 512
                          e+++  +e +++e+svlvLs+++Wpta  ++t  +k++LP++l+ t++++++fY        le++++R+Lq
   Q: 1448 agaaaaaevteeeeeENEDLFYEGAMPEVSVLVLSPRCWPTAsiCHTlnPKTCLPSYLRGTLNQYSNFYnksqsypvLEQGPQRRLQ 1534
           ************9988888999********************9999899************************************** PP
   S: 513  WqhtlgraelkaelkkgkyelqVstfQmavLLafnnsekvsveelkkatelpeeeLrrtlqsLvssk..kqvlkkep 587
           W++ lgrae+++    g ++l+Vst+Qm++LL++n+ ++vsve+l++ ++lp++ L+++++ L+ss+   +++++++
   Q: 1535 WTW-LGRAEVQF----GDQTLHVSTVQMWLLLYLNDLKAVSVENLRALSGLPADTLNQAIGLLTSSRgpLDLHEQKD 1606
           ***.********....*************************************************997777776655 PP
   
Organism Myotis lucifugus
Protein Sequence
(Fasta)
MSRGSGQVAA PRAGRWHRGW APPRPAPGAA DLRAGSGDST AGHAPSRLPI STPFGGPSAS 60
MVGELRYREF RVPLGPGLHA YPDELIRQRW GHNGHPEYQI RWLVLRRGED GEGGSSQVDC 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mlu-067036|E3,Cullin|Myotis lucifugus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGAGCCGAG GCTCCGGGCA GGTGGCAGCC CCCAGAGCTG GGCGGTGGCA CCGCGGCTGG 60
GCCCCGCCCC GCCCCGCCCC TGGGGCTGCA GACCTGCGCG CTGGCAGCGG TGACAGCACC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mlu-067036|E3,Cullin|Myotis lucifugus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR004939--APC_su10/DOC_dom
IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR021097--CPH_domain
IPR031223--CUL7
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR008979--Galactose-bd-like
IPR014722--Rib_L2_dom2
IPR011991--WHTH_DNA-bd_dom
PROSITE

PS50069--CULLIN_2
PS51284--DOC
Pfam

PF03256--ANAPC10
PF11515--Cul7
PF00888--Cullin
SMART

SM01337--APC10
SM00884--Cullin_Nedd8
Gene Ontology

GO:1990393--C:3M complex
GO:0005813--C:centrosome
GO:0031467--C:Cul7-RING ubiquitin ligase complex
GO:0005794--C:Golgi apparatus
GO:0048471--C:perinuclear region of cytoplasm
GO:0001837--P:epithelial to mesenchymal transition
GO:0000226--P:microtubule cytoskeleton organization
GO:0000281--P:mitotic cytokinesis
GO:0001890--P:placenta development
GO:0050775--P:positive regulation of dendrite morphogenesis
GO:0016567--P:protein ubiquitination
GO:0007088--P:regulation of mitotic nuclear division
GO:0006511--P:ubiquitin-dependent protein catabolic process
GO:0001570--P:vasculogenesis
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002360 Ailuropoda melanoleuca 85.94 0.00e+00 2816.00
IUUC-Ame-010611 Astyanax mexicanus 53.30 0.00e+00 755.00
IUUC-Bta-013285 Bos taurus 86.81 0.00e+00 2806.00
IUUC-Cja-019033 Callithrix jacchus 80.73 0.00e+00 2635.00
IUUC-Cfa-020695 Canis familiaris 85.38 0.00e+00 1751.00
IUUC-Cpo-021513 Cavia porcellus 76.75 0.00e+00 2469.00
IUUC-Csa-023798 Chlorocebus sabaeus 84.03 0.00e+00 2750.00
IUUC-Dno-029587 Dasypus novemcinctus 86.11 0.00e+00 1061.00
IUUC-Dor-030234 Dipodomys ordii 80.23 0.00e+00 2722.00
IUUC-Ete-032612 Echinops telfairi 75.45 0.00e+00 881.00
IUUC-Eca-033408 Equus caballus 88.43 0.00e+00 2811.00
IUUC-Fca-035483 Felis catus 87.07 0.00e+00 2870.00
IUUC-Gmo-038795 Gadus morhua 44.18 0.00e+00 935.00
IUUC-Gac-041628 Gasterosteus aculeatus 45.27 0.00e+00 1305.00
IUUC-Ggo-044721 Gorilla gorilla 83.91 0.00e+00 2709.00
IUUC-Hsa-046406 Homo sapiens 84.32 0.00e+00 2738.00
IUUC-Itr-048525 Ictidomys tridecemlineatus 84.94 0.00e+00 2713.00
IUUC-Laf-054068 Loxodonta africana 83.80 0.00e+00 2773.00
IUUC-Mcc-055464 Macaca mulatta 83.51 0.00e+00 2732.00
IUUC-Mmr-061464 Microcebus murinus 86.55 0.00e+00 2779.00
IUUC-Mmu-063413 Mus musculus 74.87 0.00e+00 2350.00
IUUC-Mpu-066146 Mustela putorius furo 87.08 0.00e+00 2749.00
IUUC-Opr-070670 Ochotona princeps 75.84 0.00e+00 2440.00
IUUC-Ont-071953 Oreochromis niloticus 49.02 0.00e+00 949.00
IUUC-Oan-073451 Ornithorhynchus anatinus 50.95 0.00e+00 1165.00
IUUC-Ocu-074155 Oryctolagus cuniculus 81.50 0.00e+00 2591.00
IUUC-Ola-087072 Oryzias latipes 48.46 0.00e+00 960.00
IUUC-Oga-089084 Otolemur garnettii 86.07 0.00e+00 2852.00
IUUC-Oar-090029 Ovis aries 85.69 0.00e+00 2800.00
IUUC-Ptr-091282 Pan troglodytes 85.28 0.00e+00 2810.00
IUUC-Pan-091883 Papio anubis 83.62 0.00e+00 2759.00
IUUC-Pab-098383 Pongo abelii 83.28 0.00e+00 2704.00
IUUC-Pca-100519 Procavia capensis 75.87 0.00e+00 853.00
IUUC-Pva-102417 Pteropus vampyrus 86.63 0.00e+00 2291.00
IUUC-Rno-105962 Rattus norvegicus 77.00 0.00e+00 2485.00
IUUC-Sar-113750 Sorex araneus 75.00 3.00e-168 586.00
IUUC-Ssc-115899 Sus scrofa 82.02 0.00e+00 2514.00
IUUC-Tsy-118860 Tarsius syrichta 82.81 0.00e+00 1130.00
IUUC-Tbe-127660 Tupaia belangeri 81.79 0.00e+00 1398.00
IUUC-Ttr-128973 Tursiops truncatus 87.23 0.00e+00 1915.00
Created Date 25-Jun-2017

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