iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000011244.3	ENSMMUT00000015733.3	ENSMMUP00000014739.2
ENSMMUG00000011244.3	ENSMMUT00000071818.1	ENSMMUP00000051102.1
ENSMMUG00000011244.3	ENSMMUT00000064754.1	ENSMMUP00000060296.1
ENSMMUG00000011244.3	ENSMMUT00000053636.1	ENSMMUP00000044880.1
ENSMMUG00000011244.3	ENSMMUT00000072479.1	ENSMMUP00000060720.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.30e-69	236.1	420	798

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw......kskkk.............avspr 71
           Gl N gN CY+N++LQ+L+++p++ +l++   +   +  +++ +++++++s+ +l++e++      k ++              a++p+
   Q: 420  GLINKGNWCYINATLQALVACPPMYHLMKF-IPLYSK-VQRPCTSTPMIDSFVRLMNEFTnmpvppKPRQAlgdkivrdirpgaAFEPT 506
           9***************************99.333333.334799***************7666654333337777888888888***** PP
   S: 72   ellkalkkeaeefs.gyeqqDaqEflaflldqleeelkk.................eknkpkeeeeeedkselsdeaeekkkkknk... 139
            +++ l   ++++s + +q+Da+E+l f+l++l+ee+ +                  kn++++eee+e++ e s++++e+   +nk   
   Q: 507  YIYRLLTVNKSSLSeKGRQEDAEEYLGFILNGLHEEMLNlkkllspnnekltisngPKNHSVTEEEQEEQGEGSEDEWEQVGPRNKtsv 595
           ******99999866599********************4456688899999999999888888888888888888887777777777777 PP
   S: 140  ........slisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekk 220
                   ++i+ +F+g+++ +++ ++  ++s + +pf++l+l++++++ +   ++qd+Les +++e+++g    y++k k+++e +++
   Q: 596  trqadfvqTPITGIFGGHIR-SVVYQQSSKESATLQPFFTLQLDIQSDKIR---TVQDALESLVARESVQG----YTTKTKQEVEISRR 676
           77787888***********9.688999999*******************99...****************8....99999********* PP
   S: 221  lklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke...kkkYeLiavvvHsG.slssGHYvayvknekgk 305
           ++l+klP+vL+lhLkRf ++++++++ k+ k++e+p  L++s+ + sp  k+k+   +++Y+L+avv+H+G s+ +GHY+++v +   +
   Q: 677  VTLEKLPPVLVLHLKRFVYEKTGGCQ-KLIKNIEYPVDLEISKELLSPGVKNKNfkcHRTYRLFAVVYHHGnSATGGHYTTDVFQIGLN 764
           *******************9998886.****************999988777777879***************************8777 PP
   S: 306  .WllfdDskVtevkeeevleetg.staYvlfYkr 337
            Wl++dD++V+++++ +v++ t+ +taY+l+Y+r
   Q: 765  gWLRIDDQTVKVISQYQVVKPTAeRTAYLLYYRR 798
           7*******************9889********98 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MPWLPSPGIG RYIFGDFSPD EFNQFFVTPR SSVELPPYSG TVLCGTQAVD KLPDGQEYQR 60
IEFGVNEVIE PSDTLPRTPS YSISSTLNPQ APEFILGCTT SKTTPDGITK EANYGSIDCQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGCCCCGCG GCGCGCGGCC AGTGCGCAGG CGCGGCGGCC GATGCGAGTG TGTATGTGCG 60
GGCGAGAAGA TGGCGGCGGC GGGGGAAGCA GCGTGAGCAG CCGGAGGAAC GCCGAGTCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR009818--Ataxin-2_C
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF07145--PAM2
PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000082	Aegilops tauschii	30.41	3.00e-44	173.00
IUUC-Aml-001584	Ailuropoda melanoleuca	88.13	0.00e+00	1330.00
IUUC-Atr-002927	Amborella trichopoda	35.22	7.00e-58	218.00
IUUC-Apl-003988	Anas platyrhynchos	78.42	0.00e+00	1149.00
IUUC-Aca-004461	Anolis carolinensis	88.92	7.00e-164	569.00
IUUC-Aly-006038	Arabidopsis lyrata	35.90	5.00e-54	205.00
IUUC-Ath-007328	Arabidopsis thaliana	35.64	9.00e-53	201.00
IUUC-Ago-007717	Ashbya gossypii	30.11	3.00e-43	170.00
IUUC-Acl-008188	Aspergillus clavatus	32.91	3.00e-62	233.00
IUUC-Afl-008456	Aspergillus flavus	37.42	4.00e-47	182.00
IUUC-Afu-009067	Aspergillus fumigatus	36.02	4.00e-65	243.00
IUUC-Ani-009483	Aspergillus nidulans	33.26	3.00e-62	233.00
IUUC-Ang-009639	Aspergillus niger	35.20	6.00e-60	225.00
IUUC-Aor-010040	Aspergillus oryzae	35.37	1.00e-59	224.00
IUUC-Ate-010310	Aspergillus terreus	31.60	2.00e-61	230.00
IUUC-Ame-011012	Astyanax mexicanus	74.45	9.00e-163	567.00
IUUC-Bgr-012311	Blumeria graminis	34.59	4.00e-43	169.00
IUUC-Bta-013299	Bos taurus	87.15	0.00e+00	1266.00
IUUC-Bci-013783	Botrytis cinerea	36.76	2.00e-58	221.00
IUUC-Bdi-015039	Brachypodium distachyon	31.58	4.00e-49	189.00
IUUC-Bol-015806	Brassica oleracea	36.73	7.00e-62	231.00
IUUC-Bra-017076	Brassica rapa	36.99	3.00e-62	233.00
IUUC-Cja-018715	Callithrix jacchus	95.89	0.00e+00	1502.00
IUUC-Cfa-020194	Canis familiaris	89.27	0.00e+00	1349.00
IUUC-Cpo-022272	Cavia porcellus	74.62	0.00e+00	1052.00
IUUC-Cre-022713	Chlamydomonas reinhardtii	34.11	3.00e-34	140.00
IUUC-Csa-023310	Chlorocebus sabaeus	99.24	0.00e+00	1522.00
IUUC-Cho-024966	Choloepus hoffmanni	78.89	0.00e+00	967.00
IUUC-Cin-025616	Ciona intestinalis	47.61	1.00e-104	374.00
IUUC-Csv-026043	Ciona savignyi	46.34	9.00e-98	350.00
IUUC-Cgl-026421	Colletotrichum gloeosporioides	34.05	2.00e-46	181.00
IUUC-Cne-026962	Cryptococcus neoformans	34.70	4.00e-50	193.00
IUUC-Cme-027113	Cyanidioschyzon merolae	31.15	1.00e-37	151.00
IUUC-Dre-028072	Danio rerio	78.28	0.00e+00	716.00
IUUC-Dno-029489	Dasypus novemcinctus	88.68	0.00e+00	1375.00
IUUC-Dor-031068	Dipodomys ordii	73.12	2.00e-137	483.00
IUUC-Dse-031553	Dothistroma septosporum	37.11	3.00e-56	213.00
IUUC-Dme-031759	Drosophila melanogaster	40.95	3.00e-83	303.00
IUUC-Ete-032549	Echinops telfairi	77.62	0.00e+00	887.00
IUUC-Eca-033380	Equus caballus	87.01	0.00e+00	1347.00
IUUC-Eeu-034818	Erinaceus europaeus	83.98	0.00e+00	1253.00
IUUC-Fca-035535	Felis catus	86.62	0.00e+00	1206.00
IUUC-Fal-036627	Ficedula albicollis	76.45	0.00e+00	1105.00
IUUC-Fox-037904	Fusarium oxysporum	36.04	9.00e-53	202.00
IUUC-Fso-038170	Fusarium solani	33.49	3.00e-52	200.00
IUUC-Gmo-039499	Gadus morhua	70.21	0.00e+00	665.00
IUUC-Ggr-040042	Gaeumannomyces graminis	35.37	5.00e-61	229.00
IUUC-Gga-040571	Gallus gallus	78.36	0.00e+00	1137.00
IUUC-Gac-041345	Gasterosteus aculeatus	76.51	0.00e+00	664.00
IUUC-Gma-044407	Glycine max	34.78	2.00e-58	219.00
IUUC-Ggo-044652	Gorilla gorilla	97.98	0.00e+00	1533.00
IUUC-Hsa-045864	Homo sapiens	98.23	0.00e+00	1540.00
IUUC-Hvu-047071	Hordeum vulgare	32.50	6.00e-52	198.00
IUUC-Itr-048216	Ictidomys tridecemlineatus	90.05	0.00e+00	1015.00
IUUC-Kpa-049132	Komagataella pastoris	30.04	1.00e-45	177.00
IUUC-Lch-050040	Latimeria chalumnae	69.20	0.00e+00	927.00
IUUC-Loc-052449	Lepisosteus oculatus	79.35	0.00e+00	711.00
IUUC-Lma-053248	Leptosphaeria maculans	36.07	7.00e-57	215.00
IUUC-Laf-054121	Loxodonta africana	88.27	0.00e+00	1333.00
IUUC-Meu-056873	Macropus eugenii	72.84	0.00e+00	827.00
IUUC-Mor-057243	Magnaporthe oryzae	33.93	2.00e-58	221.00
IUUC-Mpo-057439	Magnaporthe poae	35.64	1.00e-60	228.00
IUUC-Mtr-058457	Medicago truncatula	34.36	1.00e-56	214.00
IUUC-Mla-058929	Melampsora laricipopulina	31.17	4.00e-56	213.00
IUUC-Mga-060157	Meleagris gallopavo	76.32	0.00e+00	1140.00
IUUC-Mvi-060442	Microbotryum violaceum	33.84	3.00e-56	213.00
IUUC-Mmr-061062	Microcebus murinus	92.89	0.00e+00	1473.00
IUUC-Mdo-062798	Monodelphis domestica	81.46	0.00e+00	1209.00
IUUC-Mmu-064050	Mus musculus	82.85	0.00e+00	1266.00
IUUC-Mac-065619	Musa acuminata	34.27	3.00e-53	202.00
IUUC-Mpu-066554	Mustela putorius furo	87.89	0.00e+00	1307.00
IUUC-Mlu-068003	Myotis lucifugus	87.25	0.00e+00	1322.00
IUUC-Nfi-068612	Neosartorya fischeri	34.46	3.00e-63	236.00
IUUC-Ncr-068878	Neurospora crassa	35.14	2.00e-51	198.00
IUUC-Nle-069661	Nomascus leucogenys	98.61	0.00e+00	1514.00
IUUC-Opr-070944	Ochotona princeps	75.54	2.00e-168	585.00
IUUC-Ont-071266	Oreochromis niloticus	58.10	0.00e+00	799.00
IUUC-Oan-073442	Ornithorhynchus anatinus	80.00	0.00e+00	1130.00
IUUC-Ocu-073788	Oryctolagus cuniculus	79.62	0.00e+00	1131.00
IUUC-Oba-075085	Oryza barthii	33.45	1.00e-37	150.00
IUUC-Obr-076663	Oryza brachyantha	32.65	2.00e-45	177.00
IUUC-Ogl-076937	Oryza glaberrima	29.85	6.00e-48	185.00
IUUC-Ogu-078909	Oryza glumaepatula	30.63	2.00e-46	180.00
IUUC-Oin-079617	Oryza indica	30.67	2.00e-47	184.00
IUUC-Olo-081043	Oryza longistaminata	25.75	9.00e-25	108.00
IUUC-Ome-081646	Oryza meridionalis	24.74	1.00e-23	105.00
IUUC-Oni-082914	Oryza nivara	29.57	3.00e-46	180.00
IUUC-Oru-084878	Oryza rufipogon	29.57	3.00e-46	180.00
IUUC-Osa-085822	Oryza sativa	30.93	5.00e-50	192.00
IUUC-Ola-086931	Oryzias latipes	57.38	0.00e+00	780.00
IUUC-Oga-088443	Otolemur garnettii	92.17	0.00e+00	1440.00
IUUC-Oar-089325	Ovis aries	84.47	0.00e+00	1185.00
IUUC-Ptr-091584	Pan troglodytes	94.95	0.00e+00	1438.00
IUUC-Pan-092551	Papio anubis	97.60	0.00e+00	1488.00
IUUC-Psi-093366	Pelodiscus sinensis	73.96	0.00e+00	694.00
IUUC-Pno-095136	Phaeosphaeria nodorum	34.96	1.00e-51	197.00
IUUC-Ppa-095574	Physcomitrella patens	36.22	4.00e-59	222.00
IUUC-Pfo-097462	Poecilia formosa	77.04	0.00e+00	694.00
IUUC-Pab-098547	Pongo abelii	98.48	0.00e+00	1509.00
IUUC-Pop-099529	Populus trichocarpa	36.29	3.00e-61	229.00
IUUC-Pca-101066	Procavia capensis	79.42	0.00e+00	1174.00
IUUC-Ppe-102110	Prunus persica	36.13	2.00e-58	219.00
IUUC-Pva-103015	Pteropus vampyrus	83.23	0.00e+00	1247.00
IUUC-Ptt-103998	Puccinia triticina	33.17	4.00e-53	202.00
IUUC-Pte-104417	Pyrenophora teres	33.42	3.00e-54	206.00
IUUC-Pyt-104820	Pyrenophora triticirepentis	34.69	2.00e-54	207.00
IUUC-Rno-105533	Rattus norvegicus	83.50	0.00e+00	1261.00
IUUC-Sce-106160	Saccharomyces cerevisiae	28.05	3.00e-37	150.00
IUUC-Sha-106590	Sarcophilus harrisii	80.71	0.00e+00	1211.00
IUUC-Sja-107669	Schizosaccharomyces japonicus	35.85	1.00e-57	217.00
IUUC-Spo-108353	Schizosaccharomyces pombe	37.23	1.00e-64	240.00
IUUC-Ssl-108599	Sclerotinia sclerotiorum	36.22	5.00e-58	219.00
IUUC-Smo-108842	Selaginella moellendorffii	36.20	2.00e-37	149.00
IUUC-Sit-110781	Setaria italica	31.75	2.00e-55	210.00
IUUC-Sly-111797	Solanum lycopersicum	33.76	5.00e-55	208.00
IUUC-Stu-112188	Solanum tuberosum	34.77	1.00e-55	210.00
IUUC-Sbi-114862	Sorghum bicolor	32.23	4.00e-45	176.00
IUUC-Sre-115162	Sporisorium reilianum	34.57	5.00e-66	246.00
IUUC-Ssc-115505	Sus scrofa	95.47	1.00e-165	575.00
IUUC-Tgu-116535	Taeniopygia guttata	76.42	0.00e+00	1107.00
IUUC-Tru-117542	Takifugu rubripes	57.13	0.00e+00	803.00
IUUC-Tni-120200	Tetraodon nigroviridis	57.71	0.00e+00	799.00
IUUC-Tca-121548	Theobroma cacao	34.60	2.00e-43	170.00
IUUC-Tre-122124	Trichoderma reesei	33.67	2.00e-61	230.00
IUUC-Tvi-122457	Trichoderma virens	34.85	4.00e-54	206.00
IUUC-Tae-125646	Triticum aestivum	33.67	2.00e-54	207.00
IUUC-Tme-127180	Tuber melanosporum	39.08	1.00e-68	254.00
IUUC-Tbe-127530	Tupaia belangeri	75.23	0.00e+00	1055.00
IUUC-Ttr-128549	Tursiops truncatus	80.08	0.00e+00	1194.00
IUUC-Uma-129381	Ustilago maydis	33.62	3.00e-64	240.00
IUUC-Vda-129889	Verticillium dahliae	32.11	2.00e-52	201.00
IUUC-Vpa-130100	Vicugna pacos	81.86	0.00e+00	1215.00
IUUC-Vvi-131366	Vitis vinifera	36.39	6.00e-63	234.00
IUUC-Xtr-132048	Xenopus tropicalis	63.24	0.00e+00	900.00
IUUC-Xma-133593	Xiphophorus maculatus	77.52	0.00e+00	691.00
IUUC-Yli-134338	Yarrowia lipolytica	30.42	2.00e-32	134.00
IUUC-Zma-135586	Zea mays	30.98	4.00e-48	185.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence