iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066591

Ensembl Protein ID

ENSMPUP00000016197.1

UniProt Accession

M3YXY7; M3YXY7_MUSPF

Genbank Protein ID

ENSMPUP00000016197

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01076823

Gene Name

PACSIN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000016300.1	ENSMPUT00000016441.1	ENSMPUP00000016197.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	7.30e-17	61.1	430	486

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++lydye+q+ deL++k+Gd ++ i ++e ++gW+kg + ++g+ Gl P+n+ve ++
   Q: 430  RVRALYDYEGQEHDELSFKAGDELTKI-EDEDEQGWCKG-RLDNGQVGLYPANYVEAIQ 486
           799************************.9**********.59*************9885 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MSVAYDDSVG VEVSSDSFWE VGNYKRTVKR IDDGHRLCSD LMNCLHERAR IEKAYAQQLT 60
EWARRWRQLV EKGPQYGTLE KAWTAVMSEA EKVSELHLEV KASLMNEDFE KIKNWQKEAF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTCCTCAGG ACTCCGCTTG TGGCCCCGGG AAGCCACTGT GTGATTCCGG CCTTCCTCAG 60
CGCCCCGGTG GAGAGCAGCT GCTTCCGCTC ATGACTGAGG CATGCCATCC GCCAGCAAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR031160--F_BAR
IPR001060--FCH_dom
IPR028521--PACSIN2
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0005901--C:caveola
GO:0005911--C:cell-cell junction
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0019898--C:extrinsic component of membrane
GO:0005925--C:focal adhesion
GO:0016607--C:nuclear speck
GO:0055038--C:recycling endosome membrane
GO:0070300--F:phosphatidic acid binding
GO:0030036--P:actin cytoskeleton organization
GO:0070836--P:caveola assembly
GO:0072584--P:caveolin-mediated endocytosis
GO:0048858--P:cell projection morphogenesis
GO:0045806--P:negative regulation of endocytosis
GO:0097320--P:plasma membrane tubulation
GO:0036010--P:protein localization to endosome

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001887	Ailuropoda melanoleuca	98.97	0.00e+00	917.00
IUUC-Apl-003574	Anas platyrhynchos	88.50	0.00e+00	790.00
IUUC-Aca-004251	Anolis carolinensis	82.89	0.00e+00	764.00
IUUC-Ame-011756	Astyanax mexicanus	66.73	0.00e+00	683.00
IUUC-Bta-013193	Bos taurus	93.62	0.00e+00	844.00
IUUC-Cja-018756	Callithrix jacchus	95.27	0.00e+00	855.00
IUUC-Cfa-020545	Canis familiaris	98.56	0.00e+00	942.00
IUUC-Cpo-022000	Cavia porcellus	89.92	0.00e+00	914.00
IUUC-Csa-024030	Chlorocebus sabaeus	93.48	0.00e+00	759.00
IUUC-Cin-025707	Ciona intestinalis	42.74	8.00e-108	384.00
IUUC-Csv-026244	Ciona savignyi	41.48	3.00e-54	204.00
IUUC-Dre-028104	Danio rerio	63.62	3.00e-168	584.00
IUUC-Dno-029429	Dasypus novemcinctus	94.93	0.00e+00	820.00
IUUC-Dor-030122	Dipodomys ordii	86.63	0.00e+00	784.00
IUUC-Dme-032120	Drosophila melanogaster	43.26	2.00e-109	389.00
IUUC-Eca-033367	Equus caballus	94.03	0.00e+00	869.00
IUUC-Eeu-034821	Erinaceus europaeus	78.40	0.00e+00	703.00
IUUC-Fca-036079	Felis catus	97.65	0.00e+00	901.00
IUUC-Fal-036682	Ficedula albicollis	88.51	0.00e+00	788.00
IUUC-Gmo-039681	Gadus morhua	65.44	3.00e-158	551.00
IUUC-Gga-040717	Gallus gallus	88.72	0.00e+00	790.00
IUUC-Gac-042262	Gasterosteus aculeatus	64.83	5.00e-176	610.00
IUUC-Ggo-044841	Gorilla gorilla	94.24	0.00e+00	819.00
IUUC-Hsa-046411	Homo sapiens	94.24	0.00e+00	818.00
IUUC-Itr-049063	Ictidomys tridecemlineatus	94.24	0.00e+00	840.00
IUUC-Loc-051975	Lepisosteus oculatus	71.49	0.00e+00	703.00
IUUC-Laf-053839	Loxodonta africana	91.44	0.00e+00	849.00
IUUC-Mcc-055783	Macaca mulatta	94.03	0.00e+00	818.00
IUUC-Mga-060087	Meleagris gallopavo	82.55	0.00e+00	718.00
IUUC-Mmr-060827	Microcebus murinus	94.44	0.00e+00	874.00
IUUC-Mmu-064109	Mus musculus	93.83	0.00e+00	868.00
IUUC-Mlu-067826	Myotis lucifugus	96.71	0.00e+00	898.00
IUUC-Nle-069797	Nomascus leucogenys	94.44	0.00e+00	820.00
IUUC-Oan-073076	Ornithorhynchus anatinus	86.38	3.00e-162	564.00
IUUC-Ocu-074425	Oryctolagus cuniculus	94.03	0.00e+00	844.00
IUUC-Ola-087556	Oryzias latipes	66.21	4.00e-169	587.00
IUUC-Oga-089009	Otolemur garnettii	86.85	0.00e+00	804.00
IUUC-Oar-089806	Ovis aries	94.03	0.00e+00	847.00
IUUC-Ptr-091111	Pan troglodytes	93.83	0.00e+00	815.00
IUUC-Pan-091749	Papio anubis	91.30	0.00e+00	805.00
IUUC-Psi-093704	Pelodiscus sinensis	88.51	0.00e+00	809.00
IUUC-Pfo-096680	Poecilia formosa	64.33	1.00e-173	602.00
IUUC-Pab-098584	Pongo abelii	93.99	4.00e-160	557.00
IUUC-Pva-102649	Pteropus vampyrus	94.86	0.00e+00	858.00
IUUC-Rno-105431	Rattus norvegicus	93.44	0.00e+00	895.00
IUUC-Sha-106641	Sarcophilus harrisii	91.85	0.00e+00	842.00
IUUC-Sar-113461	Sorex araneus	83.13	0.00e+00	746.00
IUUC-Ssc-115349	Sus scrofa	96.91	0.00e+00	869.00
IUUC-Tgu-116876	Taeniopygia guttata	88.72	0.00e+00	788.00
IUUC-Tru-118306	Takifugu rubripes	68.00	5.00e-180	623.00
IUUC-Tsy-118901	Tarsius syrichta	84.78	1.00e-158	552.00
IUUC-Tni-120120	Tetraodon nigroviridis	68.57	0.00e+00	636.00
IUUC-Xtr-132925	Xenopus tropicalis	82.34	0.00e+00	766.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence