iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-094036

Ensembl Protein ID

ENSPSIP00000018263.1

UniProt Accession

K7GDA2; K7GDA2_PELSI

Genbank Protein ID

ENSPSIP00000018263

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

AGCU01049576

Gene Name

UCHL3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000016245.1	ENSPSIT00000018349.1	ENSPSIP00000018263.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	8.40e-62	209.4	30	245

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/UCH

   S: 17   lftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqvigNsCatyAll 105
           +++++++++g++ d+q+ ++y++dpe l+++++pv+++lllF+++ek+e++r+++   + ++ +++d+ ++++f+kq+i+N+C+t++l+
   Q: 30   VINQFLKQLGIHPDWQFVDVYGMDPELLSMVPRPVCAVLLLFPVTEKYETFRTEE--EERIKAQGQDVRSSVYFMKQTINNACGTIGLI 116
           89**************************************************766..5589**************************** PP
   S: 106  svllncedkl.ldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvsyvningrlyel 193
           ++++n+ +k+ ++  +tl++++  + ++spe++a+ l++ ++++++h+s a+++++++p+ +       +k  +hf+++vn++ +lyel
   Q: 117  HAIANNREKMnFESDSTLKKFLADSLSMSPEERAKYLETYEAIRVTHESSAHEGQTEAPSID-------EKVDLHFIALVNVGSHLYEL 198
           ***********************************************************888.......8899**************** PP
   S: 194  dglkpfPldlgkkketeelkdklkvvraflerikllesdeirfnllaivad 244
           dg+kpfP+++g++++++ l+d+++v+++f+er    + +e+rfn++a++a+
   Q: 199  DGRKPFPINHGQTSDDTFLEDAVEVCKKFMER----DPEELRFNAIALSAA 245
           ********************************....9**********9875 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MMIGHGGLVA VNGGGRTGVT IVSFLLYFQV INQFLKQLGI HPDWQFVDVY GMDPELLSMV 60
PRPVCAVLLL FPVTEKYETF RTEEEERIKA QGQDVRSSVY FMKQTINNAC GTIGLIHAIA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGATGGGGAG GGGATGATGA TAGGGCACGG GGGCTTGGTG GCTGTAAATG GAGGGGGCAG 60
AACTGGTGTT ACAATTGTCT CTTTTCTGCT TTATTTTCAG GTCATTAATC AGGTGAGTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH

PROSITE

PS00140--UCH_1

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001344	Ailuropoda melanoleuca	86.64	1.00e-108	385.00
IUUC-Atr-002931	Amborella trichopoda	44.50	2.00e-45	174.00
IUUC-Apl-003949	Anas platyrhynchos	90.58	1.00e-111	394.00
IUUC-Aca-004924	Anolis carolinensis	87.32	7.00e-107	379.00
IUUC-Ago-007950	Ashbya gossypii	34.26	2.00e-25	108.00
IUUC-Acl-008305	Aspergillus clavatus	35.84	3.00e-33	135.00
IUUC-Ani-009339	Aspergillus nidulans	36.28	6.00e-34	137.00
IUUC-Ame-011157	Astyanax mexicanus	74.54	2.00e-91	328.00
IUUC-Bta-012673	Bos taurus	86.18	7.00e-108	382.00
IUUC-Cfa-020371	Canis familiaris	84.21	1.00e-89	322.00
IUUC-Cpo-022036	Cavia porcellus	83.87	5.00e-104	369.00
IUUC-Csa-023854	Chlorocebus sabaeus	85.71	6.00e-107	379.00
IUUC-Cin-025545	Ciona intestinalis	48.37	2.00e-60	224.00
IUUC-Cne-026914	Cryptococcus neoformans	34.93	3.00e-27	114.00
IUUC-Cme-027216	Cyanidioschyzon merolae	38.57	2.00e-24	105.00
IUUC-Dre-028356	Danio rerio	72.81	7.00e-90	322.00
IUUC-Dme-032146	Drosophila melanogaster	48.85	2.00e-53	201.00
IUUC-Eca-033220	Equus caballus	86.18	1.00e-107	382.00
IUUC-Fca-036421	Felis catus	86.64	1.00e-108	385.00
IUUC-Fal-036773	Ficedula albicollis	84.84	7.00e-113	399.00
IUUC-Gmo-039468	Gadus morhua	71.56	4.00e-76	276.00
IUUC-Gga-041205	Gallus gallus	93.06	3.00e-111	394.00
IUUC-Gac-041629	Gasterosteus aculeatus	70.23	6.00e-82	296.00
IUUC-Ggo-044533	Gorilla gorilla	86.92	3.00e-107	380.00
IUUC-Hsa-046754	Homo sapiens	86.64	1.00e-108	385.00
IUUC-Itr-047992	Ictidomys tridecemlineatus	84.83	2.00e-67	247.00
IUUC-Lch-049685	Latimeria chalumnae	78.50	9.00e-98	348.00
IUUC-Loc-051988	Lepisosteus oculatus	77.31	3.00e-96	343.00
IUUC-Lma-053316	Leptosphaeria maculans	39.65	5.00e-39	154.00
IUUC-Laf-053985	Loxodonta africana	85.98	4.00e-106	376.00
IUUC-Mcc-055888	Macaca mulatta	86.32	4.00e-105	373.00
IUUC-Mla-058942	Melampsora laricipopulina	44.50	1.00e-37	149.00
IUUC-Mga-059702	Meleagris gallopavo	93.90	2.00e-111	394.00
IUUC-Mvi-060249	Microbotryum violaceum	39.91	6.00e-31	127.00
IUUC-Mmr-061284	Microcebus murinus	85.52	9.00e-68	249.00
IUUC-Mdo-062639	Monodelphis domestica	74.80	5.00e-104	370.00
IUUC-Mmu-063299	Mus musculus	86.18	6.00e-108	382.00
IUUC-Mpu-066769	Mustela putorius furo	86.64	1.00e-108	385.00
IUUC-Mlu-066937	Myotis lucifugus	85.25	4.00e-107	380.00
IUUC-Nle-069175	Nomascus leucogenys	87.26	5.00e-106	376.00
IUUC-Opr-070652	Ochotona princeps	85.22	5.00e-50	190.00
IUUC-Ont-072170	Oreochromis niloticus	73.02	2.00e-85	307.00
IUUC-Oan-073247	Ornithorhynchus anatinus	86.00	2.00e-43	166.00
IUUC-Ocu-074422	Oryctolagus cuniculus	86.64	2.00e-108	384.00
IUUC-Ola-086893	Oryzias latipes	70.70	1.00e-80	291.00
IUUC-Olu-087858	Ostreococcus lucimarinus	41.01	2.00e-41	161.00
IUUC-Oga-088055	Otolemur garnettii	86.92	3.00e-107	380.00
IUUC-Oar-090319	Ovis aries	85.71	2.00e-107	380.00
IUUC-Pan-092714	Papio anubis	86.38	4.00e-106	376.00
IUUC-Pma-094412	Petromyzon marinus	64.58	9.00e-49	185.00
IUUC-Ppa-095519	Physcomitrella patens	49.07	1.00e-54	206.00
IUUC-Pfo-096182	Poecilia formosa	70.51	6.00e-83	299.00
IUUC-Pab-098216	Pongo abelii	86.11	9.00e-73	265.00
IUUC-Pgr-103430	Puccinia graminis	44.54	2.00e-41	162.00
IUUC-Ptt-103955	Puccinia triticina	47.53	3.00e-42	164.00
IUUC-Pte-104414	Pyrenophora teres	37.22	3.00e-31	128.00
IUUC-Pyt-104753	Pyrenophora triticirepentis	32.60	5.00e-28	117.00
IUUC-Rno-105096	Rattus norvegicus	84.33	3.00e-106	377.00
IUUC-Sce-106412	Saccharomyces cerevisiae	31.58	1.00e-21	96.30
IUUC-Sha-106677	Sarcophilus harrisii	87.39	1.00e-111	395.00
IUUC-Ssl-108641	Sclerotinia sclerotiorum	35.96	8.00e-34	136.00
IUUC-Sre-114961	Sporisorium reilianum	40.58	6.00e-29	120.00
IUUC-Ssc-115255	Sus scrofa	86.32	2.00e-105	374.00
IUUC-Tgu-117003	Taeniopygia guttata	92.56	3.00e-111	394.00
IUUC-Tru-118330	Takifugu rubripes	63.53	1.00e-58	221.00
IUUC-Tni-120042	Tetraodon nigroviridis	67.84	1.00e-61	231.00
IUUC-Tca-120976	Theobroma cacao	44.19	4.00e-46	177.00
IUUC-Vpa-130783	Vicugna pacos	85.22	1.00e-49	189.00
IUUC-Xtr-132428	Xenopus tropicalis	72.69	1.00e-92	331.00
IUUC-Xma-134245	Xiphophorus maculatus	69.30	4.00e-82	296.00
IUUC-Yli-134570	Yarrowia lipolytica	38.16	2.00e-31	128.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence