iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-012780

Ensembl Protein ID

ENSBTAP00000056202.1

UniProt Accession

G3N2T3; G3N2T3_BOVIN

Genbank Protein ID

ENSBTAP00000056202

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02070084

Gene Name

ARHGAP4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000047531.1	ENSBTAT00000063618.1	ENSBTAP00000056202.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.30e-10	41.2	753	801

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 8    vlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           + + y++ +  eLt+++Gd++++  +e  +++W++g  e +g rGl+P+ +++
   Q: 753  ACFAYTGRTAQELTFQRGDILRL--HERASGDWWRG--EHAGARGLIPHKYIT 801
           789********************..59*********..9************96 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MATHGKLRRE RGPQADYEAQ VKEMRWQLGE QLRCLELQGE LRRELLQELA EFMRRRAEVE 60
LEYSRGLDKL VERFSGRGGR LGGSSREHQS FRKEPSLLSP LHCWAVLLQQ TRQQSRESTA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGCCTGGCC CGCTCGAGGC CGCGTGGGAG TATAAGGGCT CAACGGCGCG GCCGCCCGGC 60
GGTCATGGCC ACGCATGGGA AACTACGCCG AGAGCGAGGG CCGCAGGCTG ACTATGAGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR031160--F_BAR
IPR001060--FCH_dom
IPR008936--Rho_GTPase_activation_prot
IPR000198--RhoGAP_dom
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50238--RHOGAP
PS50002--SH3

Pfam

PF00611--FCH
PF00620--RhoGAP
PF00018--SH3_1

SMART

SM00055--FCH
SM00324--RhoGAP
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005096--F:GTPase activator activity
GO:0048365--F:Rac GTPase binding
GO:0030336--P:negative regulation of cell migration
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011131	Astyanax mexicanus	48.41	0.00e+00	702.00
IUUC-Hsa-045896	Homo sapiens	87.39	2.00e-52	198.00
IUUC-Mmu-064211	Mus musculus	78.07	7.00e-37	146.00
IUUC-Pma-094731	Petromyzon marinus	32.38	3.00e-22	101.00
IUUC-Pab-097683	Pongo abelii	27.41	1.00e-09	58.20
IUUC-Ssc-115790	Sus scrofa	86.71	0.00e+00	1477.00
IUUC-Tru-118770	Takifugu rubripes	46.61	0.00e+00	682.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence