iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cre-022919

UUCD1 version

UUC-ChR-00461

Ensembl Protein ID

EDP08369

UniProt Accession

A8HYD8; A8HYD8_CHLRE

Genbank Protein ID

ADF43147.1; EDP08369.1

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

GU814014; DS496110

Gene Name

UBCH1p; CHLREDRAFT_182375

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CHLREDRAFT_182375	EDP08369	EDP08369

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	1.00e-62	212.0	1	316

Active Site

Position(s)	Description	Evidence
78	Nucleophile	{ECO:0000256\|PIRSR:PIRSR038120-1}
155	Proton donor	{ECO:0000256\|PIRSR:PIRSR038120-1}

Domain Profile

DUB/UCH

   S: 6    kewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqvigNsCatyAlls 106
           +ew+++esdPg+ft+l+e+ gvk++ qveel+sLd+  l+ +  pv gl++lFk++++               + d     ++ffakqvi+N+Cat+A+l 
   Q: 1    MEWTTIESDPGVFTELIENIGVKGV-QVEELWSLDQ--LREL-SPVFGLVFLFKWKKEPVRPA--T-------TTDA---GQVFFAKQVISNACATQAILN 85
           59***********************.********99..7888.9***********87655444..2.......2333...467****************** PP
   S: 107  vllncedklldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvsyvningrlyeldglkpfPldlgkkk 207
            lln +   ldlGt+l +l+e+   ++p +k+la++n++ ++ +hns+ar+e+   ++ +d++   +  +a+hf+syv+++g+l+eldgl++ P++l  + 
   Q: 86   ILLNVKAPGLDLGTELANLREFVSDFDPTMKGLAISNSDLIRTAHNSFARPEPLVPDNDKDDE---KSGDAYHFISYVPVGGKLFELDGLQEGPIELCDC- 182
           *******99********************************************9888655444...489******************************6. PP
   S: 208  eteelkdklkvvraflerikllesdeirfnllaivadrrviktlrlnvlkid....................keLlkLlkdieseeekieaqlddekekrk 288
            ++++ dk+   +  + r++ + + eirfnl+a+v +r  i   rl     +                    +  ++ l + e+e+++ ++ l+ e+ k +
   Q: 183  TDDDWLDKVGPHI--TARMERYAASEIRFNLMALVGNRVDIFSSRLAAATAQrdqlaaaaaaadgmsdedlaH-AQAKLLEAETEVANLQEALAAEQAKHR 280
           567899***9999..8888889***************99999****88877799**************88843.344555679****************** PP
   S: 289  kfkiddirRtenydeficifikdlaregilrklvee 324
            +  ++ rR++ny+  ++ ++k +a  g++  l e+
   Q: 281  TWHEENVRRKHNYVPCLFQLLKLMAARGQMGPLLER 316
           *************************99999888775 PP

Organism

Chlamydomonas reinhardtii

Protein Sequence
(Fasta)

MEWTTIESDP GVFTELIENI GVKGVQVEEL WSLDQLRELS PVFGLVFLFK WKKEPVRPAT 60
TTDAGQVFFA KQVISNACAT QAILNILLNV KAPGLDLGTE LANLREFVSD FDPTMKGLAI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTAGGATGGA GTGGACGACA ATAGAATCGG ACCCAGGTGC GGACCCAGGA TCTCCATGCC 60
GCATGCCTTG GTGCTGGGCC TCGAATGCAG CGACCTACAT ACATGCAGCA CTGTAGCATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR017390--Ubiquitinyl_hydrolase_UCH37

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005737--C:cytoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

cre:CHLREDRAFT_182375

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000936	Aegilops tauschii	51.17	5.00e-92	328.00
IUUC-Aml-001866	Ailuropoda melanoleuca	46.54	1.00e-76	278.00
IUUC-Atr-002966	Amborella trichopoda	46.45	1.00e-77	281.00
IUUC-Apl-003306	Anas platyrhynchos	42.41	4.00e-71	259.00
IUUC-Aca-004763	Anolis carolinensis	45.79	2.00e-77	280.00
IUUC-Aly-005581	Arabidopsis lyrata	50.76	3.00e-82	296.00
IUUC-Ath-007283	Arabidopsis thaliana	50.30	2.00e-85	306.00
IUUC-Ago-007999	Ashbya gossypii	36.48	6.00e-35	139.00
IUUC-Acl-008231	Aspergillus clavatus	49.13	5.00e-56	209.00
IUUC-Afl-008557	Aspergillus flavus	46.96	2.00e-54	204.00
IUUC-Afu-008988	Aspergillus fumigatus	48.28	9.00e-57	211.00
IUUC-Ani-009420	Aspergillus nidulans	39.51	4.00e-55	206.00
IUUC-Ang-009859	Aspergillus niger	47.90	2.00e-55	207.00
IUUC-Aor-010145	Aspergillus oryzae	46.96	2.00e-54	204.00
IUUC-Ate-010347	Aspergillus terreus	44.80	4.00e-54	202.00
IUUC-Ame-010791	Astyanax mexicanus	45.45	6.00e-80	288.00
IUUC-Bgr-012298	Blumeria graminis	38.20	1.00e-48	184.00
IUUC-Bta-013251	Bos taurus	46.25	1.00e-76	277.00
IUUC-Bci-013786	Botrytis cinerea	37.89	4.00e-56	209.00
IUUC-Bdi-014132	Brachypodium distachyon	51.63	2.00e-86	310.00
IUUC-Bol-015611	Brassica oleracea	50.15	4.00e-86	309.00
IUUC-Bra-017769	Brassica rapa	50.46	3.00e-86	310.00
IUUC-Cel-018604	Caenorhabditis elegans	41.12	1.00e-68	251.00
IUUC-Cja-019768	Callithrix jacchus	42.49	2.00e-71	260.00
IUUC-Cfa-020207	Canis familiaris	46.54	1.00e-76	278.00
IUUC-Cpo-021925	Cavia porcellus	44.97	8.00e-72	261.00
IUUC-Csa-023958	Chlorocebus sabaeus	45.94	9.00e-77	278.00
IUUC-Cho-024928	Choloepus hoffmanni	48.00	2.00e-14	71.60
IUUC-Cin-025771	Ciona intestinalis	43.17	7.00e-71	258.00
IUUC-Csv-026149	Ciona savignyi	41.72	4.00e-70	256.00
IUUC-Cgl-026424	Colletotrichum gloeosporioides	37.18	7.00e-47	179.00
IUUC-Cne-026955	Cryptococcus neoformans	33.53	3.00e-44	170.00
IUUC-Cme-027104	Cyanidioschyzon merolae	35.15	1.00e-43	168.00
IUUC-Dre-027409	Danio rerio	45.15	1.00e-79	288.00
IUUC-Dno-028921	Dasypus novemcinctus	46.54	2.00e-76	276.00
IUUC-Dor-030891	Dipodomys ordii	36.00	7.00e-35	140.00
IUUC-Dse-031170	Dothistroma septosporum	38.89	3.00e-52	196.00
IUUC-Dme-031677	Drosophila melanogaster	44.75	9.00e-77	278.00
IUUC-Ete-032707	Echinops telfairi	33.33	3.00e-40	157.00
IUUC-Eca-033776	Equus caballus	45.15	3.00e-68	249.00
IUUC-Eeu-035305	Erinaceus europaeus	45.90	5.00e-40	156.00
IUUC-Fca-035846	Felis catus	42.90	8.00e-72	262.00
IUUC-Fal-037597	Ficedula albicollis	44.48	4.00e-68	249.00
IUUC-Fox-037670	Fusarium oxysporum	47.98	7.00e-50	189.00
IUUC-Fso-038243	Fusarium solani	46.90	4.00e-50	189.00
IUUC-Gmo-038499	Gadus morhua	42.77	8.00e-69	251.00
IUUC-Ggr-039975	Gaeumannomyces graminis	44.58	9.00e-48	182.00
IUUC-Gga-040904	Gallus gallus	47.09	7.00e-80	288.00
IUUC-Gac-042058	Gasterosteus aculeatus	46.54	2.00e-77	280.00
IUUC-Gma-043030	Glycine max	48.67	2.00e-85	307.00
IUUC-Ggo-044699	Gorilla gorilla	43.59	5.00e-68	249.00
IUUC-Hsa-046227	Homo sapiens	46.54	3.00e-77	280.00
IUUC-Hvu-047359	Hordeum vulgare	51.20	1.00e-89	321.00
IUUC-Itr-048989	Ictidomys tridecemlineatus	42.41	9.00e-72	261.00
IUUC-Lch-049829	Latimeria chalumnae	45.48	1.00e-76	278.00
IUUC-Lpe-050899	Leersia perrieri	51.08	4.00e-85	306.00
IUUC-Loc-052264	Lepisosteus oculatus	46.71	3.00e-76	276.00
IUUC-Lma-053110	Leptosphaeria maculans	45.05	3.00e-46	177.00
IUUC-Laf-053639	Loxodonta africana	46.54	1.00e-76	278.00
IUUC-Mcc-055506	Macaca mulatta	45.94	1.00e-76	278.00
IUUC-Meu-056267	Macropus eugenii	39.37	1.00e-41	162.00
IUUC-Mor-057001	Magnaporthe oryzae	48.25	8.00e-52	195.00
IUUC-Mpo-057608	Magnaporthe poae	43.72	7.00e-33	131.00
IUUC-Mtr-057731	Medicago truncatula	48.96	2.00e-86	310.00
IUUC-Mla-059016	Melampsora laricipopulina	45.92	7.00e-45	171.00
IUUC-Mga-060178	Meleagris gallopavo	44.81	2.00e-71	260.00
IUUC-Mvi-060353	Microbotryum violaceum	32.73	3.00e-41	160.00
IUUC-Mmr-060738	Microcebus murinus	46.54	4.00e-77	279.00
IUUC-Mdo-062266	Monodelphis domestica	51.71	2.00e-57	213.00
IUUC-Mmu-063619	Mus musculus	46.54	1.00e-76	277.00
IUUC-Mac-065301	Musa acuminata	50.46	6.00e-91	325.00
IUUC-Mpu-066058	Mustela putorius furo	46.54	1.00e-76	278.00
IUUC-Mlu-067292	Myotis lucifugus	46.08	4.00e-77	279.00
IUUC-Nfi-068275	Neosartorya fischeri	38.79	4.00e-56	209.00
IUUC-Ncr-068713	Neurospora crassa	41.43	1.00e-57	214.00
IUUC-Nle-069013	Nomascus leucogenys	45.94	2.00e-76	277.00
IUUC-Opr-070628	Ochotona princeps	40.90	6.00e-64	235.00
IUUC-Ont-072688	Oreochromis niloticus	46.08	2.00e-77	280.00
IUUC-Oan-073004	Ornithorhynchus anatinus	49.77	1.00e-58	217.00
IUUC-Ocu-074303	Oryctolagus cuniculus	46.23	4.00e-76	276.00
IUUC-Oba-075002	Oryza barthii	49.41	9.00e-88	314.00
IUUC-Obr-076392	Oryza brachyantha	51.39	3.00e-87	313.00
IUUC-Ogl-077271	Oryza glaberrima	49.41	9.00e-88	314.00
IUUC-Ogu-078493	Oryza glumaepatula	49.70	6.00e-89	318.00
IUUC-Oin-080084	Oryza indica	49.70	6.00e-89	318.00
IUUC-Olo-080803	Oryza longistaminata	49.41	3.00e-88	316.00
IUUC-Ome-081146	Oryza meridionalis	49.41	7.00e-88	315.00
IUUC-Oni-082146	Oryza nivara	49.70	6.00e-89	318.00
IUUC-Opu-083633	Oryza punctata	51.70	6.00e-87	311.00
IUUC-Oru-084789	Oryza rufipogon	49.70	6.00e-89	318.00
IUUC-Osa-086196	Oryza sativa	49.70	6.00e-89	318.00
IUUC-Ola-087126	Oryzias latipes	46.23	1.00e-76	278.00
IUUC-Olu-087665	Ostreococcus lucimarinus	44.67	3.00e-67	246.00
IUUC-Oga-089140	Otolemur garnettii	43.19	1.00e-72	265.00
IUUC-Oar-090296	Ovis aries	46.50	7.00e-75	272.00
IUUC-Ptr-090566	Pan troglodytes	46.54	3.00e-77	280.00
IUUC-Pan-092052	Papio anubis	45.94	1.00e-76	278.00
IUUC-Psi-093723	Pelodiscus sinensis	44.82	1.00e-68	251.00
IUUC-Pma-094568	Petromyzon marinus	43.73	3.00e-54	203.00
IUUC-Pno-095120	Phaeosphaeria nodorum	45.05	3.00e-48	183.00
IUUC-Ppa-095761	Physcomitrella patens	48.54	2.00e-86	310.00
IUUC-Pfo-096210	Poecilia formosa	45.79	7.00e-78	281.00
IUUC-Pab-098463	Pongo abelii	46.54	7.00e-77	278.00
IUUC-Pop-099109	Populus trichocarpa	48.66	1.00e-86	311.00
IUUC-Pca-100108	Procavia capensis	50.84	3.00e-64	236.00
IUUC-Ppe-101176	Prunus persica	48.66	6.00e-84	302.00
IUUC-Pva-102629	Pteropus vampyrus	51.81	8.00e-68	248.00
IUUC-Pgr-103419	Puccinia graminis	42.50	4.00e-50	189.00
IUUC-Pte-104207	Pyrenophora teres	46.06	4.00e-32	129.00
IUUC-Pyt-104471	Pyrenophora triticirepentis	47.73	2.00e-51	194.00
IUUC-Rno-105579	Rattus norvegicus	40.18	1.00e-63	234.00
IUUC-Sha-106894	Sarcophilus harrisii	44.09	1.00e-62	231.00
IUUC-Sja-107732	Schizosaccharomyces japonicus	37.99	1.00e-56	211.00
IUUC-Spo-108371	Schizosaccharomyces pombe	37.95	4.00e-59	219.00
IUUC-Ssl-108467	Sclerotinia sclerotiorum	36.97	3.00e-43	166.00
IUUC-Smo-109396	Selaginella moellendorffii	51.37	7.00e-89	318.00
IUUC-Sit-110630	Setaria italica	48.64	7.00e-87	311.00
IUUC-Sly-110972	Solanum lycopersicum	48.42	3.00e-81	293.00
IUUC-Stu-112185	Solanum tuberosum	49.85	4.00e-90	322.00
IUUC-Sar-113294	Sorex araneus	40.46	6.00e-64	235.00
IUUC-Sbi-113951	Sorghum bicolor	48.64	5.00e-85	305.00
IUUC-Ssc-115501	Sus scrofa	45.13	7.00e-71	258.00
IUUC-Tgu-117152	Taeniopygia guttata	44.82	4.00e-68	249.00
IUUC-Tru-118388	Takifugu rubripes	46.54	1.00e-77	281.00
IUUC-Tsy-119109	Tarsius syrichta	46.54	6.00e-77	278.00
IUUC-Tni-120048	Tetraodon nigroviridis	46.54	5.00e-78	282.00
IUUC-Tca-121750	Theobroma cacao	48.81	7.00e-90	322.00
IUUC-Tre-122130	Trichoderma reesei	46.88	5.00e-53	199.00
IUUC-Tvi-122284	Trichoderma virens	39.27	2.00e-49	187.00
IUUC-Tae-124082	Triticum aestivum	51.81	1.00e-90	324.00
IUUC-Tur-126366	Triticum urartu	40.69	5.00e-59	219.00
IUUC-Tme-127187	Tuber melanosporum	40.19	6.00e-57	212.00
IUUC-Tbe-127619	Tupaia belangeri	40.74	4.00e-51	192.00
IUUC-Ttr-128867	Tursiops truncatus	44.63	4.00e-53	199.00
IUUC-Vda-129912	Verticillium dahliae	42.47	4.00e-61	226.00
IUUC-Vpa-130552	Vicugna pacos	52.94	5.00e-58	216.00
IUUC-Vvi-130881	Vitis vinifera	50.61	2.00e-83	300.00
IUUC-Xtr-131934	Xenopus tropicalis	45.34	3.00e-78	283.00
IUUC-Xma-133312	Xiphophorus maculatus	45.79	8.00e-78	281.00
IUUC-Yli-134487	Yarrowia lipolytica	31.76	5.00e-49	186.00
IUUC-Zma-135639	Zea mays	44.29	1.00e-76	277.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence