iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073004

UUCD1 version

UUC-OrA-00827

Ensembl Protein ID

ENSOANP00000004696.3

UniProt Accession

F6ZHF1; F6ZHF1_ORNAN

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Gene Name

UCHL5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000002960.3	ENSOANT00000004697.3	ENSOANP00000004696.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	1.20e-72	245.3	16	231

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/UCH

   S: 25   fgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqvigNsCatyAllsvllnced 113
            g+++  qvee++sL+pen++++ +pv+gl++lFk+++ +e +          +vv+++ ++tiffakqvi+N+Cat+A++svllnc++
   Q: 16   SGCRGA-QVEEIWSLEPENFEKL-KPVHGLIFLFKWQPGEEPAG---------SVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTH 93
           589999.****************.********************.........899********************************* PP
   S: 114  klldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvsyvningrlyeldglkpfPld 202
             ++lG+tls++ke+++++++ +k+lal+n++v++++hns+ar+++++ + +++++    +++afhfvsyv++ grlyeldgl++ P+d
   Q: 94   RDVHLGETLSEFKEFSQSFDAAMKGLALSNSEVIRQVHNSFARQQMFEFDAKTSAK----EEDAFHFVSYVPVSGRLYELDGLREGPID 178
           ****************************************************9887....79*************************** PP
   S: 203  lgkkketeelkdklkvvraflerikllesdeirfnllaivadrrviktlrlnvlki 258
           lg+ ++++++ ++++ v+   +ri++++++eirfnl+aiv+dr++i+++++  l+ 
   Q: 179  LGA-CNQDDWISAVRPVI--EKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQR 231
           **9.78999*********..*****************************9854443 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

KSPKRLVRCR ARSKRSGCRG AQVEEIWSLE PENFEKLKPV HGLIFLFKWQ PGEEPAGSVV 60
QDSRLDTIFF AKQVINNACA TQAIVSVLLN CTHRDVHLGE TLSEFKEFSQ SFDAAMKGLA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAATCTCCCA AACGCCTAGT CCGATGCCGC GCACGTAGTA AGCGCTCCGG TAAGGAGACC 60
GATTGATTGA CAACCATAGG TTGCAAAAGG AAGCTATGCC AAGAGGGCGG ATTTTTAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR033837--UCH37

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0031011--C:Ino80 complex
GO:0005739--C:mitochondrion
GO:0005654--C:nucleoplasm
GO:0004866--F:endopeptidase inhibitor activity
GO:0003723--F:RNA binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0048853--P:forebrain morphogenesis
GO:0021670--P:lateral ventricle development
GO:0030901--P:midbrain development
GO:0016579--P:protein deubiquitination
GO:0061136--P:regulation of proteasomal protein catabolic process
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000936	Aegilops tauschii	49.55	1.00e-59	222.00
IUUC-Aml-001866	Ailuropoda melanoleuca	96.75	4.00e-142	496.00
IUUC-Atr-002966	Amborella trichopoda	53.42	5.00e-61	227.00
IUUC-Apl-003306	Anas platyrhynchos	86.13	9.00e-135	472.00
IUUC-Aca-004763	Anolis carolinensis	95.12	2.00e-139	487.00
IUUC-Aly-005581	Arabidopsis lyrata	52.38	2.00e-57	215.00
IUUC-Ath-007283	Arabidopsis thaliana	51.90	3.00e-59	221.00
IUUC-Acl-008231	Aspergillus clavatus	42.92	1.00e-45	176.00
IUUC-Afl-008557	Aspergillus flavus	42.40	2.00e-46	178.00
IUUC-Afu-008988	Aspergillus fumigatus	44.24	4.00e-47	181.00
IUUC-Ani-009420	Aspergillus nidulans	41.77	2.00e-44	172.00
IUUC-Aor-010145	Aspergillus oryzae	42.40	2.00e-46	178.00
IUUC-Ate-010347	Aspergillus terreus	40.95	2.00e-45	175.00
IUUC-Ame-010791	Astyanax mexicanus	89.43	3.00e-134	470.00
IUUC-Bgr-012298	Blumeria graminis	42.63	3.00e-39	154.00
IUUC-Bta-013251	Bos taurus	96.34	3.00e-140	490.00
IUUC-Bci-013786	Botrytis cinerea	40.42	5.00e-47	180.00
IUUC-Bdi-014132	Brachypodium distachyon	47.77	9.00e-61	226.00
IUUC-Bol-015611	Brassica oleracea	53.64	5.00e-61	227.00
IUUC-Bra-017769	Brassica rapa	53.64	5.00e-61	227.00
IUUC-Cel-018604	Caenorhabditis elegans	49.55	1.00e-58	219.00
IUUC-Cja-019768	Callithrix jacchus	85.40	1.00e-134	472.00
IUUC-Cfa-020207	Canis familiaris	96.75	4.00e-142	496.00
IUUC-Cpo-021925	Cavia porcellus	91.46	6.00e-133	466.00
IUUC-Cre-022919	Chlamydomonas reinhardtii	51.21	5.00e-57	213.00
IUUC-Csa-023958	Chlorocebus sabaeus	95.53	2.00e-138	484.00
IUUC-Cho-024928	Choloepus hoffmanni	98.70	3.00e-42	164.00
IUUC-Cin-025771	Ciona intestinalis	58.45	2.00e-71	261.00
IUUC-Csv-026149	Ciona savignyi	62.32	4.00e-75	273.00
IUUC-Cgl-026424	Colletotrichum gloeosporioides	43.00	2.00e-47	182.00
IUUC-Cne-026955	Cryptococcus neoformans	40.37	2.00e-39	155.00
IUUC-Cme-027104	Cyanidioschyzon merolae	36.40	2.00e-35	142.00
IUUC-Dre-027409	Danio rerio	89.43	9.00e-133	465.00
IUUC-Dno-028921	Dasypus novemcinctus	95.93	7.00e-141	492.00
IUUC-Dse-031170	Dothistroma septosporum	43.32	6.00e-46	177.00
IUUC-Dme-031677	Drosophila melanogaster	58.23	2.00e-82	298.00
IUUC-Ete-032707	Echinops telfairi	74.07	4.00e-87	313.00
IUUC-Eca-033776	Equus caballus	97.53	2.00e-142	497.00
IUUC-Eeu-035305	Erinaceus europaeus	74.10	4.00e-66	244.00
IUUC-Fca-035846	Felis catus	87.18	7.00e-137	479.00
IUUC-Fal-037597	Ficedula albicollis	96.30	9.00e-134	468.00
IUUC-Fox-037670	Fusarium oxysporum	50.79	6.00e-48	183.00
IUUC-Fso-038243	Fusarium solani	50.79	2.00e-47	181.00
IUUC-Gmo-038499	Gadus morhua	82.11	3.00e-121	427.00
IUUC-Ggr-039975	Gaeumannomyces graminis	41.67	1.00e-41	162.00
IUUC-Gga-040904	Gallus gallus	95.88	8.00e-140	488.00
IUUC-Gac-042058	Gasterosteus aculeatus	88.21	6.00e-131	459.00
IUUC-Gma-043030	Glycine max	50.91	2.00e-60	225.00
IUUC-Ggo-044699	Gorilla gorilla	95.93	2.00e-141	494.00
IUUC-Hsa-046227	Homo sapiens	95.93	5.00e-141	493.00
IUUC-Hvu-047359	Hordeum vulgare	49.09	2.00e-59	221.00
IUUC-Itr-048989	Ictidomys tridecemlineatus	85.92	1.00e-136	478.00
IUUC-Lch-049829	Latimeria chalumnae	92.68	4.00e-135	473.00
IUUC-Lpe-050899	Leersia perrieri	51.43	6.00e-59	220.00
IUUC-Loc-052264	Lepisosteus oculatus	90.69	4.00e-134	469.00
IUUC-Lma-053110	Leptosphaeria maculans	44.09	8.00e-42	163.00
IUUC-Laf-053639	Loxodonta africana	96.75	4.00e-142	496.00
IUUC-Mcc-055506	Macaca mulatta	95.53	2.00e-138	484.00
IUUC-Mor-057001	Magnaporthe oryzae	45.83	3.00e-48	184.00
IUUC-Mpo-057608	Magnaporthe poae	39.76	1.00e-26	112.00
IUUC-Mtr-057731	Medicago truncatula	52.73	1.00e-65	242.00
IUUC-Mla-059016	Melampsora laricipopulina	43.17	6.00e-38	149.00
IUUC-Mga-060178	Meleagris gallopavo	96.30	5.00e-141	492.00
IUUC-Mvi-060353	Microbotryum violaceum	41.36	6.00e-44	170.00
IUUC-Mmr-060738	Microcebus murinus	95.93	4.00e-141	493.00
IUUC-Mdo-062266	Monodelphis domestica	97.34	2.00e-108	383.00
IUUC-Mmu-063619	Mus musculus	93.90	2.00e-138	484.00
IUUC-Mac-065301	Musa acuminata	52.73	7.00e-65	239.00
IUUC-Mpu-066058	Mustela putorius furo	97.15	1.00e-142	498.00
IUUC-Mlu-067292	Myotis lucifugus	95.12	3.00e-138	483.00
IUUC-Nfi-068275	Neosartorya fischeri	42.86	5.00e-46	177.00
IUUC-Ncr-068713	Neurospora crassa	41.87	1.00e-48	186.00
IUUC-Nle-069013	Nomascus leucogenys	95.12	4.00e-138	483.00
IUUC-Opr-070628	Ochotona princeps	86.08	6.00e-136	476.00
IUUC-Ont-072688	Oreochromis niloticus	89.11	3.00e-131	460.00
IUUC-Ocu-074303	Oryctolagus cuniculus	97.94	4.00e-142	497.00
IUUC-Oba-075002	Oryza barthii	50.45	2.00e-60	225.00
IUUC-Obr-076392	Oryza brachyantha	50.45	4.00e-61	227.00
IUUC-Ogl-077271	Oryza glaberrima	50.45	2.00e-60	225.00
IUUC-Ogu-078493	Oryza glumaepatula	50.45	3.00e-61	228.00
IUUC-Oin-080084	Oryza indica	50.45	3.00e-61	228.00
IUUC-Olo-080803	Oryza longistaminata	50.45	3.00e-61	228.00
IUUC-Ome-081146	Oryza meridionalis	50.00	2.00e-60	225.00
IUUC-Oni-082146	Oryza nivara	50.45	3.00e-61	228.00
IUUC-Opu-083633	Oryza punctata	50.00	2.00e-60	225.00
IUUC-Oru-084789	Oryza rufipogon	50.45	3.00e-61	228.00
IUUC-Osa-086196	Oryza sativa	50.45	3.00e-61	228.00
IUUC-Ola-087126	Oryzias latipes	89.43	2.00e-127	447.00
IUUC-Olu-087665	Ostreococcus lucimarinus	43.06	3.00e-54	204.00
IUUC-Oga-089140	Otolemur garnettii	85.71	2.00e-135	474.00
IUUC-Oar-090296	Ovis aries	96.75	2.00e-142	497.00
IUUC-Ptr-090566	Pan troglodytes	95.93	5.00e-141	493.00
IUUC-Pan-092052	Papio anubis	95.53	2.00e-138	484.00
IUUC-Psi-093723	Pelodiscus sinensis	95.88	4.00e-140	489.00
IUUC-Pma-094568	Petromyzon marinus	71.95	2.00e-99	354.00
IUUC-Pno-095120	Phaeosphaeria nodorum	45.45	3.00e-43	167.00
IUUC-Ppa-095761	Physcomitrella patens	44.85	1.00e-58	219.00
IUUC-Pfo-096210	Poecilia formosa	87.80	5.00e-131	459.00
IUUC-Pab-098463	Pongo abelii	95.93	1.00e-140	492.00
IUUC-Pop-099423	Populus trichocarpa	50.68	1.00e-59	222.00
IUUC-Pca-100108	Procavia capensis	95.54	2.00e-125	441.00
IUUC-Ppe-101176	Prunus persica	49.59	1.00e-59	222.00
IUUC-Pva-102629	Pteropus vampyrus	93.33	1.00e-130	458.00
IUUC-Pgr-103419	Puccinia graminis	44.54	2.00e-49	188.00
IUUC-Pte-104207	Pyrenophora teres	41.72	7.00e-26	108.00
IUUC-Pyt-104471	Pyrenophora triticirepentis	43.81	1.00e-47	182.00
IUUC-Rno-105579	Rattus norvegicus	83.15	1.00e-133	468.00
IUUC-Sha-106894	Sarcophilus harrisii	93.94	2.00e-129	454.00
IUUC-Sja-107732	Schizosaccharomyces japonicus	42.58	4.00e-48	184.00
IUUC-Spo-108371	Schizosaccharomyces pombe	47.09	1.00e-49	189.00
IUUC-Ssl-108467	Sclerotinia sclerotiorum	41.30	3.00e-45	174.00
IUUC-Smo-109396	Selaginella moellendorffii	49.41	6.00e-62	230.00
IUUC-Sit-110630	Setaria italica	50.68	3.00e-63	234.00
IUUC-Sly-110972	Solanum lycopersicum	53.18	8.00e-65	239.00
IUUC-Stu-112185	Solanum tuberosum	53.18	4.00e-65	241.00
IUUC-Sar-113294	Sorex araneus	78.75	1.00e-120	425.00
IUUC-Sbi-113951	Sorghum bicolor	51.60	3.00e-63	234.00
IUUC-Ssc-115501	Sus scrofa	97.94	1.00e-142	498.00
IUUC-Tgu-117152	Taeniopygia guttata	95.88	9.00e-134	468.00
IUUC-Tru-118388	Takifugu rubripes	88.21	5.00e-131	459.00
IUUC-Tsy-119109	Tarsius syrichta	96.34	2.00e-141	494.00
IUUC-Tni-120048	Tetraodon nigroviridis	88.21	2.00e-131	461.00
IUUC-Tca-121750	Theobroma cacao	52.04	5.00e-64	237.00
IUUC-Tre-122130	Trichoderma reesei	43.66	6.00e-46	177.00
IUUC-Tvi-122284	Trichoderma virens	46.11	1.00e-44	172.00
IUUC-Tae-125344	Triticum aestivum	50.00	7.00e-60	223.00
IUUC-Tur-126366	Triticum urartu	45.79	1.00e-53	202.00
IUUC-Tme-127187	Tuber melanosporum	47.14	2.00e-50	191.00
IUUC-Tbe-127619	Tupaia belangeri	86.36	8.00e-116	409.00
IUUC-Ttr-128867	Tursiops truncatus	86.94	1.00e-122	432.00
IUUC-Vda-129912	Verticillium dahliae	42.86	2.00e-45	175.00
IUUC-Vpa-130552	Vicugna pacos	97.33	2.00e-108	384.00
IUUC-Vvi-130881	Vitis vinifera	53.18	8.00e-60	223.00
IUUC-Xtr-131934	Xenopus tropicalis	85.19	4.00e-126	443.00
IUUC-Xma-133312	Xiphophorus maculatus	87.80	7.00e-131	459.00
IUUC-Zma-135639	Zea mays	53.00	4.00e-58	218.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence