iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sre-115225

Ensembl Protein ID

CBQ67700

UniProt Accession

E6ZK47; E6ZK47_SPORE

Genbank Protein ID

CBQ67700.1

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

FQ311430

Gene Name

sr11650

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
sr11650	CBQ67700	CBQ67700

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	9.20e-57	191.2	313	861
UBD/Alpha-Helix/UBA	3.10e-17	60.6	730	760

Active Site

Position(s)	Description	Evidence
322	Nucleophile	{ECO:0000256\|PIRSR:PIRSR016308-1}
811	Proton acceptor	{ECO:0000256\|PIRSR:PIRSR016308-1}

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeel.........................wkskkk......... 66
           tGl+NlgN+CYm SvLQ+L+++p +++ + +   +++l+    ++p +++ ++++k+   l                                        
   Q: 313  TGLRNLGNSCYMASVLQSLFSLPAFQKRYGDaYRPHTLACA--NQPATCFECQITKVADGLlsgryshprepqvgndsgwtpaagsE----Deqqqqqqpl 407
           7****************************995344444444..47889999999999999966666666666666666655554440....0344455667 PP
   S: 67   ...avsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvs. 163
               v p+++++ ++k +eefs+++qqDa Ef+++l+  +++e  k                    a+++  ++ ++  +++F++ l++++ c++c++v  
   Q: 408  fqkGVRPNMFKALVGKGHEEFSTMRQQDADEFFKYLVGIVQKENRK-------------------VASSDSASSLTEDPTNVFGFGLEQRLECNTCHKVRy 489
           777*************************************999922...................3345566777788899******************97 PP
   S: 164  sreepfldlslpvpgkeetkke.......................................slqdcLesftkeeelegenkyycekckkkqeaekklklkk 225
           s e +   lslpvp + + +++                                       sl +cL+ ft++eele    y+c++c++k++a+k++ +++
   Q: 490  SVERQDAGLSLPVPIRPKAATSdaatgkqpaegvhaadsastssaaasastsntaadyepvSLVECLDIFTAPEELE----YNCPSCRAKVTATKRTLFTT 586
           6666777777777777766666779***************************************************9....******************** PP
   S: 226  lPevLilhLkRfsfseeqksrekinkkvefple..Ldlspfcts...........peekqke....................................... 274
           +P+vL l+  +f  +  +++++k+   + +p+   Ldl++++ +           +     e                                       
   Q: 587  FPQVLALQVRCF--QLLNWVPQKVPVPIVVPIDtsLDLDRYLGRgkqpheeelpeD-----Esapaagagvgepewdagvmsqltsmgfpeirckkavlat 680
           ************..5567*************7668********9555555555550.....0555555555555555555555555555555555566666 PP
   S: 275  ..................................................................................................... 274
                                                                                                                
   Q: 681  gmgdaesamnwlfahmedadiddpidfaaagggsapsaaaagagpdtsmleemgftsaqarkalrlnsnnaelavawlfenaddagedaaetaaaepsgss 781
           66666666666666666666666666666666666666666666666666677777777777777777777777788888888888888888888888899 PP
   S: 275  .........kkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetg........staYvlfYkr 337
                    + +Y   + ++H+G s++sGHYva+v++  ++W+ f+D+kV   + ++  ++ +        ++aYv+f++r
   Q: 782  naipgssglPARYAVKSFISHKGpSVHSGHYVAHVRH-ADGWVFFNDEKVVRAPLTSTAKNGEdagvkglsAQAYVYFFER 861
           999999999****************************.777************98777775558***************98 PP

UBD/Alpha-Helix/UBA

   S: 10   lveMGFdreealqaLraannnleaAveyLld 40
           l+eMGF+  +a++aLr ++nn+e Av++L++
   Q: 730  LEEMGFTSAQARKALRLNSNNAELAVAWLFE 760
           566**************************97 PP

Organism

Sporisorium reilianum

Protein Sequence
(Fasta)

MACPHLSAAF TALAPPRPSQ HVHKEECTLC FDDQDGPNGI DVCLLCFNGA CTGNGDREHS 60
RLHFEKTQHA LVVNIRRTQR PAPPAEENAA PSVPKKLAIA AESDADKYDY HTVPRCLACD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTTGCC CACACCTCAG CGCCGCATTC ACCGCCCTCG CCCCACCTCG TCCTTCGCAG 60
CACGTGCACA AGGAGGAGTG TACGCTCTGC TTCGATGACC AGGATGGGCC CAACGGCATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR016652--Ubiquitinyl_hydrolase
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50030--UBA
PS00972--USP_1
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00627--UBA
PF00443--UCH
PF02148--zf-UBP

SMART

SM00165--UBA
SM00290--ZnF_UBP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000394	Aegilops tauschii	31.12	6.00e-98	350.00
IUUC-Aml-002104	Ailuropoda melanoleuca	35.59	2.00e-137	481.00
IUUC-Atr-002580	Amborella trichopoda	33.77	1.00e-112	399.00
IUUC-Apl-003774	Anas platyrhynchos	34.55	4.00e-130	457.00
IUUC-Aca-005368	Anolis carolinensis	34.62	5.00e-137	480.00
IUUC-Aly-005727	Arabidopsis lyrata	34.02	2.00e-116	411.00
IUUC-Ath-006974	Arabidopsis thaliana	34.02	4.00e-117	414.00
IUUC-Ago-007890	Ashbya gossypii	30.45	2.00e-96	344.00
IUUC-Acl-008057	Aspergillus clavatus	41.83	0.00e+00	631.00
IUUC-Afl-008547	Aspergillus flavus	42.84	3.00e-158	550.00
IUUC-Afu-008805	Aspergillus fumigatus	39.48	3.00e-154	536.00
IUUC-Ani-009441	Aspergillus nidulans	40.20	1.00e-144	504.00
IUUC-Ang-009720	Aspergillus niger	42.37	0.00e+00	627.00
IUUC-Aor-010111	Aspergillus oryzae	42.17	0.00e+00	637.00
IUUC-Ate-010531	Aspergillus terreus	39.93	4.00e-159	553.00
IUUC-Ame-011893	Astyanax mexicanus	34.58	2.00e-107	382.00
IUUC-Bgr-012183	Blumeria graminis	42.56	2.00e-180	624.00
IUUC-Bta-013179	Bos taurus	35.67	2.00e-138	484.00
IUUC-Bci-013858	Botrytis cinerea	45.69	0.00e+00	691.00
IUUC-Bdi-014904	Brachypodium distachyon	34.19	4.00e-109	387.00
IUUC-Bol-015296	Brassica oleracea	34.06	3.00e-119	421.00
IUUC-Bra-017619	Brassica rapa	33.11	4.00e-117	414.00
IUUC-Cel-018625	Caenorhabditis elegans	29.68	5.00e-81	293.00
IUUC-Cja-019063	Callithrix jacchus	35.48	5.00e-134	470.00
IUUC-Cfa-020976	Canis familiaris	36.16	1.00e-140	492.00
IUUC-Cpo-022265	Cavia porcellus	35.89	2.00e-140	491.00
IUUC-Cre-022640	Chlamydomonas reinhardtii	34.74	5.00e-63	233.00
IUUC-Csa-024177	Chlorocebus sabaeus	36.49	2.00e-125	441.00
IUUC-Cho-024702	Choloepus hoffmanni	33.94	2.00e-83	302.00
IUUC-Cin-025411	Ciona intestinalis	33.14	4.00e-105	374.00
IUUC-Csv-026347	Ciona savignyi	31.21	3.00e-102	364.00
IUUC-Cgl-026667	Colletotrichum gloeosporioides	46.04	0.00e+00	629.00
IUUC-Cne-026831	Cryptococcus neoformans	48.84	0.00e+00	718.00
IUUC-Cme-027335	Cyanidioschyzon merolae	31.40	3.00e-87	315.00
IUUC-Dre-027982	Danio rerio	33.04	1.00e-106	379.00
IUUC-Dno-029034	Dasypus novemcinctus	35.45	6.00e-138	483.00
IUUC-Dor-030479	Dipodomys ordii	37.03	2.00e-65	242.00
IUUC-Dse-031467	Dothistroma septosporum	43.35	0.00e+00	651.00
IUUC-Dme-032075	Drosophila melanogaster	32.98	1.00e-105	375.00
IUUC-Ete-032865	Echinops telfairi	31.89	8.00e-114	402.00
IUUC-Eca-034059	Equus caballus	35.60	3.00e-138	484.00
IUUC-Eeu-035304	Erinaceus europaeus	36.93	7.00e-126	443.00
IUUC-Fca-035515	Felis catus	35.56	2.00e-138	484.00
IUUC-Fal-037271	Ficedula albicollis	35.34	1.00e-127	449.00
IUUC-Fox-037745	Fusarium oxysporum	45.24	0.00e+00	686.00
IUUC-Fso-038158	Fusarium solani	45.17	0.00e+00	671.00
IUUC-Gmo-039071	Gadus morhua	34.16	9.00e-117	412.00
IUUC-Ggr-040098	Gaeumannomyces graminis	43.96	0.00e+00	625.00
IUUC-Gga-040635	Gallus gallus	34.72	6.00e-136	476.00
IUUC-Gac-042528	Gasterosteus aculeatus	33.30	3.00e-114	404.00
IUUC-Gma-043614	Glycine max	32.92	4.00e-112	397.00
IUUC-Ggo-044602	Gorilla gorilla	35.79	4.00e-138	483.00
IUUC-Hsa-045959	Homo sapiens	35.79	4.00e-138	483.00
IUUC-Hvu-047563	Hordeum vulgare	35.86	1.00e-101	362.00
IUUC-Itr-048712	Ictidomys tridecemlineatus	35.00	8.00e-138	483.00
IUUC-Kpa-049156	Komagataella pastoris	37.67	8.00e-153	532.00
IUUC-Lch-049648	Latimeria chalumnae	34.89	4.00e-125	440.00
IUUC-Lpe-051523	Leersia perrieri	32.88	3.00e-106	377.00
IUUC-Loc-052072	Lepisosteus oculatus	31.68	1.00e-114	405.00
IUUC-Lma-053216	Leptosphaeria maculans	44.33	0.00e+00	630.00
IUUC-Laf-054327	Loxodonta africana	35.67	3.00e-136	477.00
IUUC-Mcc-055443	Macaca mulatta	35.45	3.00e-136	477.00
IUUC-Meu-056298	Macropus eugenii	34.80	6.00e-95	340.00
IUUC-Mor-057106	Magnaporthe oryzae	45.58	0.00e+00	694.00
IUUC-Mpo-057589	Magnaporthe poae	43.94	0.00e+00	638.00
IUUC-Mtr-058680	Medicago truncatula	34.58	6.00e-119	420.00
IUUC-Mla-058903	Melampsora laricipopulina	43.41	0.00e+00	661.00
IUUC-Mga-059669	Meleagris gallopavo	34.42	1.00e-127	448.00
IUUC-Mvi-060476	Microbotryum violaceum	47.96	0.00e+00	689.00
IUUC-Mmr-060575	Microcebus murinus	35.44	5.00e-138	483.00
IUUC-Mdo-062183	Monodelphis domestica	35.03	5.00e-136	476.00
IUUC-Mmu-063592	Mus musculus	35.56	5.00e-138	483.00
IUUC-Mac-065634	Musa acuminata	31.66	1.00e-102	365.00
IUUC-Mpu-066082	Mustela putorius furo	35.69	4.00e-139	487.00
IUUC-Mlu-067345	Myotis lucifugus	35.37	1.00e-135	475.00
IUUC-Nfi-068558	Neosartorya fischeri	41.78	1.00e-171	595.00
IUUC-Ncr-068960	Neurospora crassa	45.28	0.00e+00	652.00
IUUC-Nle-070173	Nomascus leucogenys	36.16	2.00e-139	488.00
IUUC-Opr-070556	Ochotona princeps	35.48	1.00e-138	485.00
IUUC-Ont-071502	Oreochromis niloticus	33.48	5.00e-117	413.00
IUUC-Oan-072959	Ornithorhynchus anatinus	42.04	2.00e-51	193.00
IUUC-Ocu-074861	Oryctolagus cuniculus	36.15	7.00e-140	489.00
IUUC-Oba-075109	Oryza barthii	33.18	7.00e-109	386.00
IUUC-Obr-076292	Oryza brachyantha	33.68	4.00e-106	377.00
IUUC-Ogl-077065	Oryza glaberrima	34.19	6.00e-116	410.00
IUUC-Ogu-078776	Oryza glumaepatula	33.18	8.00e-113	399.00
IUUC-Oin-080048	Oryza indica	34.30	1.00e-116	412.00
IUUC-Olo-080711	Oryza longistaminata	32.81	2.00e-102	365.00
IUUC-Ome-081506	Oryza meridionalis	33.50	1.00e-104	372.00
IUUC-Oni-082320	Oryza nivara	32.31	6.00e-106	376.00
IUUC-Opu-083801	Oryza punctata	33.29	5.00e-105	374.00
IUUC-Oru-085139	Oryza rufipogon	32.31	1.00e-105	375.00
IUUC-Osa-085713	Oryza sativa	34.30	3.00e-117	414.00
IUUC-Ola-086951	Oryzias latipes	33.11	5.00e-112	397.00
IUUC-Olu-087822	Ostreococcus lucimarinus	33.68	4.00e-102	364.00
IUUC-Oga-088625	Otolemur garnettii	34.59	1.00e-135	475.00
IUUC-Oar-089995	Ovis aries	35.85	3.00e-138	484.00
IUUC-Ptr-090640	Pan troglodytes	35.90	2.00e-139	488.00
IUUC-Pan-091974	Papio anubis	35.04	5.00e-135	473.00
IUUC-Psi-093957	Pelodiscus sinensis	34.86	3.00e-137	480.00
IUUC-Pma-094242	Petromyzon marinus	38.90	3.00e-70	257.00
IUUC-Pno-094835	Phaeosphaeria nodorum	44.54	6.00e-163	566.00
IUUC-Ppa-095901	Physcomitrella patens	34.62	4.00e-125	440.00
IUUC-Pfo-097148	Poecilia formosa	33.45	1.00e-117	416.00
IUUC-Pab-098068	Pongo abelii	33.33	9.00e-114	402.00
IUUC-Pop-098943	Populus trichocarpa	33.33	2.00e-108	385.00
IUUC-Pca-100738	Procavia capensis	36.31	3.00e-100	357.00
IUUC-Ppe-101315	Prunus persica	32.77	1.00e-110	392.00
IUUC-Pva-102154	Pteropus vampyrus	35.79	6.00e-140	489.00
IUUC-Pgr-103343	Puccinia graminis	45.24	3.00e-164	570.00
IUUC-Ptt-103928	Puccinia triticina	39.03	1.00e-153	535.00
IUUC-Pte-104306	Pyrenophora teres	43.79	2.00e-167	580.00
IUUC-Pyt-104696	Pyrenophora triticirepentis	43.81	3.00e-174	603.00
IUUC-Rno-105801	Rattus norvegicus	35.78	1.00e-138	485.00
IUUC-Sce-106304	Saccharomyces cerevisiae	29.43	8.00e-95	339.00
IUUC-Sha-107635	Sarcophilus harrisii	34.94	6.00e-136	476.00
IUUC-Sja-107678	Schizosaccharomyces japonicus	38.42	4.00e-163	566.00
IUUC-Spo-108144	Schizosaccharomyces pombe	38.70	2.00e-165	574.00
IUUC-Smo-108703	Selaginella moellendorffii	35.86	5.00e-121	426.00
IUUC-Sit-110728	Setaria italica	33.95	2.00e-118	418.00
IUUC-Sly-111523	Solanum lycopersicum	33.79	2.00e-119	422.00
IUUC-Sar-113733	Sorex araneus	34.52	1.00e-59	223.00
IUUC-Sbi-114419	Sorghum bicolor	33.45	1.00e-114	405.00
IUUC-Ssc-115686	Sus scrofa	35.33	5.00e-139	486.00
IUUC-Tgu-117346	Taeniopygia guttata	34.58	1.00e-131	462.00
IUUC-Tru-118350	Takifugu rubripes	32.20	8.00e-113	399.00
IUUC-Tsy-119278	Tarsius syrichta	31.87	3.00e-94	338.00
IUUC-Tni-120658	Tetraodon nigroviridis	32.19	4.00e-106	377.00
IUUC-Tca-121585	Theobroma cacao	34.21	5.00e-110	390.00
IUUC-Tre-122043	Trichoderma reesei	44.73	0.00e+00	643.00
IUUC-Tvi-122303	Trichoderma virens	44.42	0.00e+00	654.00
IUUC-Tae-123798	Triticum aestivum	33.91	1.00e-114	405.00
IUUC-Tur-126732	Triticum urartu	31.12	7.00e-104	369.00
IUUC-Tme-126909	Tuber melanosporum	46.83	0.00e+00	687.00
IUUC-Tbe-127699	Tupaia belangeri	34.01	4.00e-48	184.00
IUUC-Ttr-129119	Tursiops truncatus	37.57	2.00e-68	252.00
IUUC-Uma-129599	Ustilago maydis	80.16	0.00e+00	1352.00
IUUC-Vda-129688	Verticillium dahliae	45.74	0.00e+00	642.00
IUUC-Vpa-130170	Vicugna pacos	33.43	2.00e-51	196.00
IUUC-Vvi-131116	Vitis vinifera	33.07	8.00e-111	392.00
IUUC-Xtr-131953	Xenopus tropicalis	33.44	4.00e-115	407.00
IUUC-Xma-133837	Xiphophorus maculatus	33.33	7.00e-117	413.00
IUUC-Yli-134510	Yarrowia lipolytica	42.87	2.00e-161	561.00
IUUC-Zma-135786	Zea mays	33.26	5.00e-108	383.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence