iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pfo-096991

Ensembl Protein ID

ENSPFOP00000008112.2

UniProt Accession

A0A087XQQ9; A0A087XQQ9_POEFO

Genbank Protein ID

ENSPFOP00000008112

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AYCK01006008

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPFOG00000008112.2	ENSPFOT00000008124.2	ENSPFOP00000008112.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.10e-27	94.1	305	343
E3 adaptor/Cullin RING/APC_C/CDC20	1.50e-143	478.2	170	472

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH  +v++l++ +d  +l+sG++D+++ vW+ ++ v+++
   Q: 305  GHRQEVCGLKWsPDhQHLASGGNDNKLLVWNSSSLVPVQ 343
           8***********999****************88888776 PP

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+kvldapel+ddfylnL+dWs+ n l+v+Lg++vylwsa+t++v++l+dl  ++d+vtsv w e+g+l+avGt+kg v+i+D++  +k
   Q: 170  PFKVLDAPELQDDFYLNLVDWSAGNLLSVGLGACVYLWSACTSQVTRLCDLsVDGDSVTSVCWNERGSLVAVGTHKGYVQIWDAAGGRK 258
           689************************************************999*********************************** PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdasssePlkkfke 177
           +  l+ghsarvgaL+Wn e+lssGsrd+ il+rdvr++    ++lq+h+qevCGlkw+ d+++LasGGnDn++ vw++ss  P++++++
   Q: 259  LTCLEGHSARVGALAWNGEQLSSGSRDRVILQRDVRTPPAAERRLQGHRQEVCGLKWSPDHQHLASGGNDNKLLVWNSSSLVPVQQYSD 347
           ***************************************************************************************** PP
   S: 178  hkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkgh 266
           h aavkaiawsP+q++lLasGGGtaDrc++fwntltg+ l++ dtgsqvc+l+wsk+++elvsthG+++n+i +wkypsl++va+l+gh
   Q: 348  HLAAVKAIAWSPHQHGLLASGGGTADRCLRFWNTLTGQALQSTDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGH 436
           ***************************************************************************************** PP
   S: 267  eaRvlslalspdgeaivtaagDetlrfwklfdkkka 302
           ++Rvl+la+spdgeaivt+agDetlrfw++f+k++ 
   Q: 437  SYRVLYLAVSPDGEAIVTGAGDETLRFWNVFSKTRC 472
           ********************************9875 PP

Organism

Poecilia formosa

Protein Sequence
(Fasta)

MDQEYERRLL RQINHQNLPT ERRMTKSLGA ACSPLSVKSG DRFIPTRAGS NWSINFHYAN 60
ENCRSPAQNH KAKDASSDSS KDAVAYAALL RNELLGAGIE TVAEPHADDR RHEVLAPDSC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACGGCCTTAA CTCATTCAAA ATGTGCTGAA GTCACCAGCG AGTGTCGCTG TTGCGCCGTC 60
TCCAAAGCTC AGTACAGGCA ACAGAAGTCA GCTCAAAGCA AAAAATTTCT GCCACAGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011773	Astyanax mexicanus	90.76	0.00e+00	911.00
IUUC-Dre-027860	Danio rerio	91.58	0.00e+00	919.00
IUUC-Fox-037814	Fusarium oxysporum	64.49	9.00e-124	436.00
IUUC-Gmo-039431	Gadus morhua	87.47	0.00e+00	882.00
IUUC-Gac-041566	Gasterosteus aculeatus	92.61	0.00e+00	893.00
IUUC-Loc-052240	Lepisosteus oculatus	86.65	0.00e+00	872.00
IUUC-Ont-071725	Oreochromis niloticus	94.46	0.00e+00	952.00
IUUC-Ola-086983	Oryzias latipes	93.29	0.00e+00	942.00
IUUC-Olu-087647	Ostreococcus lucimarinus	52.84	5.00e-99	355.00
IUUC-Sit-110550	Setaria italica	53.85	3.00e-128	451.00
IUUC-Tru-118528	Takifugu rubripes	91.68	0.00e+00	880.00
IUUC-Tni-120312	Tetraodon nigroviridis	92.21	0.00e+00	879.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence