iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Csv-026372

Ensembl Protein ID

ENSCSAVP00000018015.1

UniProt Accession

H2ZK99; H2ZK99_CIOSA

Protein Name

Defective in cullin neddylation protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAVG00000010611.1	ENSCSAVT00000018211.1	ENSCSAVP00000018014.1
ENSCSAVG00000010611.1	ENSCSAVT00000018212.1	ENSCSAVP00000018015.1
ENSCSAVG00000010611.1	ENSCSAVT00000018213.1	ENSCSAVP00000018016.1
ENSCSAVG00000010611.1	ENSCSAVT00000018214.1	ENSCSAVP00000018017.1
ENSCSAVG00000010611.1	ENSCSAVT00000018215.1	ENSCSAVP00000018018.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/DCUN1	43.82	4.00e-50	195.00	IUUC-Hsa-046994
UBD/Alpha-Helix/UBA	43.82	4.00e-50	195.00	IUUC-Hsa-046994

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ciona savignyi

Functional Description
(View)

Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.

Protein Sequence
(Fasta)

QHKLKSSQRE KVRQFVSLTN LGEKAAISCL SKHDWRLDIA SDSFFNEPEA YFTERRTYVE 60
KRKLESLFNA LKAIIFEKFM KSTLLAIISY FPATLSYWLY SPEVCSSIWS RLNTPAFTND 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGAGAGTAGA ATTGATATAA TCATTAATCT AGGTAACAGA CCAAGTCTGA TGATATCTCA 60
ATGGTAAAAC TATTCTTAGT ATCACACCAG TGAAACTGTC CTGAAGGAGA TTAAAGAACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR005176--PONY_dom
IPR009060--UBA-like

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001879	Ailuropoda melanoleuca	43.82	2.00e-54	203.00
IUUC-Atr-002662	Amborella trichopoda	42.25	2.00e-16	77.80
IUUC-Apl-003933	Anas platyrhynchos	42.46	1.00e-55	207.00
IUUC-Aca-005269	Anolis carolinensis	43.43	5.00e-53	199.00
IUUC-Ame-011763	Astyanax mexicanus	41.70	1.00e-52	197.00
IUUC-Bta-013561	Bos taurus	41.88	5.00e-47	179.00
IUUC-Cja-018854	Callithrix jacchus	44.05	5.00e-56	209.00
IUUC-Cfa-020523	Canis familiaris	42.31	1.00e-47	181.00
IUUC-Cpo-022196	Cavia porcellus	43.20	2.00e-54	203.00
IUUC-Csa-023108	Chlorocebus sabaeus	43.65	1.00e-55	207.00
IUUC-Cho-024373	Choloepus hoffmanni	42.23	3.00e-47	180.00
IUUC-Cin-025269	Ciona intestinalis	56.39	3.00e-77	279.00
IUUC-Dre-028247	Danio rerio	42.00	9.00e-54	201.00
IUUC-Dno-028974	Dasypus novemcinctus	43.82	2.00e-54	203.00
IUUC-Dor-030143	Dipodomys ordii	43.03	2.00e-54	203.00
IUUC-Dme-032197	Drosophila melanogaster	39.15	3.00e-43	167.00
IUUC-Ete-032371	Echinops telfairi	43.82	3.00e-54	203.00
IUUC-Eca-033242	Equus caballus	43.82	3.00e-54	203.00
IUUC-Eeu-035317	Erinaceus europaeus	43.82	2.00e-54	203.00
IUUC-Fca-036061	Felis catus	43.82	3.00e-54	203.00
IUUC-Fal-036715	Ficedula albicollis	42.86	3.00e-56	209.00
IUUC-Gmo-038750	Gadus morhua	43.25	3.00e-56	209.00
IUUC-Gga-040224	Gallus gallus	42.17	2.00e-53	201.00
IUUC-Gac-041478	Gasterosteus aculeatus	44.05	5.00e-57	212.00
IUUC-Ggo-044972	Gorilla gorilla	43.82	7.00e-55	205.00
IUUC-Hsa-046994	Homo sapiens	43.82	7.00e-55	205.00
IUUC-Hvu-047636	Hordeum vulgare	45.59	4.00e-15	72.80
IUUC-Itr-047902	Ictidomys tridecemlineatus	41.50	9.00e-51	191.00
IUUC-Lch-049751	Latimeria chalumnae	42.46	6.00e-55	205.00
IUUC-Loc-051976	Lepisosteus oculatus	41.43	1.00e-54	204.00
IUUC-Laf-053972	Loxodonta africana	43.65	4.00e-57	213.00
IUUC-Mcc-054700	Macaca mulatta	43.82	2.00e-55	206.00
IUUC-Meu-056791	Macropus eugenii	41.73	5.00e-53	199.00
IUUC-Mor-056909	Magnaporthe oryzae	25.27	6.00e-16	76.30
IUUC-Mga-060072	Meleagris gallopavo	42.86	3.00e-56	209.00
IUUC-Mmr-060851	Microcebus murinus	43.82	3.00e-54	203.00
IUUC-Mdo-063074	Monodelphis domestica	44.09	4.00e-54	204.00
IUUC-Mmu-063954	Mus musculus	43.43	1.00e-53	201.00
IUUC-Mpu-066870	Mustela putorius furo	42.31	1.00e-47	181.00
IUUC-Mlu-067701	Myotis lucifugus	44.62	5.00e-54	202.00
IUUC-Nle-069475	Nomascus leucogenys	43.82	3.00e-55	206.00
IUUC-Opr-070265	Ochotona princeps	75.00	3.00e-23	100.00
IUUC-Ont-071813	Oreochromis niloticus	44.84	5.00e-58	216.00
IUUC-Oan-073031	Ornithorhynchus anatinus	43.82	3.00e-54	203.00
IUUC-Ocu-074648	Oryctolagus cuniculus	43.82	3.00e-54	203.00
IUUC-Ola-086371	Oryzias latipes	44.44	1.00e-57	214.00
IUUC-Oga-088621	Otolemur garnettii	43.25	4.00e-55	206.00
IUUC-Oar-090405	Ovis aries	43.43	1.00e-53	201.00
IUUC-Ptr-091595	Pan troglodytes	43.82	7.00e-55	205.00
IUUC-Pan-092825	Papio anubis	43.82	2.00e-55	207.00
IUUC-Psi-093110	Pelodiscus sinensis	42.31	2.00e-47	180.00
IUUC-Pfo-096813	Poecilia formosa	44.44	7.00e-57	212.00
IUUC-Pab-098197	Pongo abelii	41.35	1.00e-47	181.00
IUUC-Pca-100195	Procavia capensis	43.82	2.00e-54	203.00
IUUC-Pva-102691	Pteropus vampyrus	43.43	5.00e-56	209.00
IUUC-Rno-105554	Rattus norvegicus	43.82	3.00e-54	203.00
IUUC-Sha-106542	Sarcophilus harrisii	41.83	3.00e-54	203.00
IUUC-Sar-113509	Sorex araneus	51.39	3.00e-17	80.10
IUUC-Ssc-115547	Sus scrofa	43.82	2.00e-54	203.00
IUUC-Tgu-117196	Taeniopygia guttata	43.43	3.00e-56	209.00
IUUC-Tru-118316	Takifugu rubripes	42.69	3.00e-57	213.00
IUUC-Tsy-119599	Tarsius syrichta	43.82	2.00e-54	204.00
IUUC-Tni-120542	Tetraodon nigroviridis	42.74	2.00e-54	204.00
IUUC-Tvi-122607	Trichoderma virens	27.80	9.00e-17	79.00
IUUC-Tme-126878	Tuber melanosporum	27.13	2.00e-19	88.20
IUUC-Ttr-129086	Tursiops truncatus	36.65	2.00e-38	150.00
IUUC-Vpa-130048	Vicugna pacos	33.47	9.00e-33	132.00
IUUC-Xtr-132527	Xenopus tropicalis	46.18	3.00e-57	213.00
IUUC-Xma-133580	Xiphophorus maculatus	44.22	3.00e-57	213.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence