iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073031

UUCD1 version

UUC-OrA-00550

Ensembl Protein ID

ENSOANP00000030126.1

UniProt Accession

K7E9B9; K7E9B9_ORNAN

Protein Name

DCN1-like protein; Defective in cullin neddylation protein 1-like protein

Gene Name

DCUN1D1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000011254.3	ENSOANT00000039370.1	ENSOANP00000030126.1
ENSOANG00000011254.3	ENSOANT00000017834.2	ENSOANP00000017831.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	2.00e-91	305.4	78	264
UBD/Alpha-Helix/UBA	4.80e-07	29.9	24	62

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 2    skkkleelferYkdpqed.ligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktleselk 89
           ++kkle+l++rYkdpq++ +igi+g+++fc+dl++dp++i+vL++awk++aat+cefs++ef+dg+t+lgcdsiekl+++l+++e+elk
   Q: 78   DRKKLEQLYNRYKDPQDEnKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQEFMDGMTELGCDSIEKLKAQLPKMEQELK 166
           78**************999********************************************************************** PP
   S: 90   deqkfkdiYrfafnfakdkgqksldldtaialwkLllaerefklldawlkfLeeekkksiskDtWnllLefskviakdlsnYdeegaWP 178
           +  +fkd+Y+f+fnfak++gqk+ldl++aia+w+L+l++r fk+ld+w+kfL e++k+si+kDtWnllL+fs++ia+d+snYdeegaWP
   Q: 167  EPGRFKDFYQFTFNFAKNPGQKGLDLEMAIAYWNLVLNGR-FKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWP 254
           ***************************************9.************************************************ PP
   S: 179  vliDefveyl 188
           vliD+fve++
   Q: 255  VLIDDFVEFA 264
           ********97 PP

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlve.MGFdreealqaLraannnleaAveyLl 39
           +++dk++q++  +  ++++a+ +L ++++ l++A+++++
   Q: 24   SQKDKVRQFMIfTQSSEKTAVSCLSQNDWKLDVATDNFF 62
           699********9999999*******************99 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MDISLTRPCD HDILPYNDNK LKSSQKDKVR QFMIFTQSSE KTAVSCLSQN DWKLDVATDN 60
FFQNPELYIR ESVKGSLDRK KLEQLYNRYK DPQDENKIGI DGIQQFCDDL ALDPASISVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTTTGGTTG CCAGAGCCAA AGCTCACACG TTGATCTTCT TTGTAGGTGG CTTACGATGA 60
TGGTGTCATG ACTGTGTCAG CTCAGGTCTC ATTCTGTTGG CCACAAGATG ATGATCAGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR005176--PONY_dom
IPR009060--UBA-like

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0000151--C:ubiquitin ligase complex
GO:0097602--F:cullin family protein binding
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0032182--F:ubiquitin-like protein binding
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000561	Aegilops tauschii	43.50	1.00e-60	225.00
IUUC-Aml-001879	Ailuropoda melanoleuca	99.22	2.00e-152	530.00
IUUC-Atr-002662	Amborella trichopoda	38.69	2.00e-25	108.00
IUUC-Apl-003451	Anas platyrhynchos	97.32	8.00e-150	521.00
IUUC-Aca-005269	Anolis carolinensis	96.51	9.00e-149	518.00
IUUC-Aly-006285	Arabidopsis lyrata	37.80	2.00e-44	171.00
IUUC-Ath-007531	Arabidopsis thaliana	44.31	3.00e-58	217.00
IUUC-Ago-007806	Ashbya gossypii	23.74	5.00e-20	90.50
IUUC-Acl-008172	Aspergillus clavatus	27.38	3.00e-23	101.00
IUUC-Afl-008569	Aspergillus flavus	29.37	2.00e-29	122.00
IUUC-Ani-009241	Aspergillus nidulans	26.71	3.00e-25	108.00
IUUC-Ang-009664	Aspergillus niger	28.40	3.00e-24	104.00
IUUC-Ate-010414	Aspergillus terreus	30.23	6.00e-31	127.00
IUUC-Ame-011763	Astyanax mexicanus	89.15	1.00e-136	478.00
IUUC-Bgr-011991	Blumeria graminis	30.74	1.00e-25	109.00
IUUC-Bta-013561	Bos taurus	99.18	2.00e-144	503.00
IUUC-Bci-013824	Botrytis cinerea	32.28	9.00e-31	126.00
IUUC-Bdi-014138	Brachypodium distachyon	43.90	9.00e-62	229.00
IUUC-Bol-016110	Brassica oleracea	43.90	1.00e-57	215.00
IUUC-Bra-017111	Brassica rapa	43.90	2.00e-57	214.00
IUUC-Cel-018441	Caenorhabditis elegans	36.13	1.00e-50	192.00
IUUC-Cja-019502	Callithrix jacchus	99.22	2.00e-152	530.00
IUUC-Cfa-020523	Canis familiaris	99.59	6.00e-145	505.00
IUUC-Cpo-022196	Cavia porcellus	98.45	3.00e-151	526.00
IUUC-Cre-022620	Chlamydomonas reinhardtii	36.88	1.00e-50	192.00
IUUC-Csa-023551	Chlorocebus sabaeus	99.61	5.00e-153	532.00
IUUC-Cho-024373	Choloepus hoffmanni	97.67	2.00e-145	507.00
IUUC-Cin-025269	Ciona intestinalis	61.48	2.00e-99	354.00
IUUC-Csv-026372	Ciona savignyi	41.80	5.00e-51	193.00
IUUC-Cne-026950	Cryptococcus neoformans	31.60	1.00e-30	125.00
IUUC-Dre-028247	Danio rerio	88.85	3.00e-137	479.00
IUUC-Dno-028974	Dasypus novemcinctus	99.61	5.00e-153	532.00
IUUC-Dor-030696	Dipodomys ordii	88.76	6.00e-132	462.00
IUUC-Dse-031365	Dothistroma septosporum	27.52	1.00e-25	109.00
IUUC-Dme-032197	Drosophila melanogaster	64.11	2.00e-92	331.00
IUUC-Ete-032371	Echinops telfairi	99.22	2.00e-152	530.00
IUUC-Eca-033242	Equus caballus	99.61	7.00e-153	531.00
IUUC-Eeu-035317	Erinaceus europaeus	100.00	4.00e-153	532.00
IUUC-Fca-036061	Felis catus	99.61	7.00e-153	531.00
IUUC-Fal-037372	Ficedula albicollis	97.32	7.00e-150	521.00
IUUC-Gmo-038885	Gadus morhua	88.76	9.00e-137	478.00
IUUC-Gga-040935	Gallus gallus	98.45	9.00e-152	528.00
IUUC-Gac-041937	Gasterosteus aculeatus	88.37	3.00e-135	473.00
IUUC-Gma-043545	Glycine max	42.28	9.00e-58	216.00
IUUC-Ggo-044468	Gorilla gorilla	98.46	1.00e-150	524.00
IUUC-Hsa-046089	Homo sapiens	99.61	5.00e-153	532.00
IUUC-Hvu-047636	Hordeum vulgare	39.84	7.00e-23	99.40
IUUC-Itr-047902	Ictidomys tridecemlineatus	75.78	1.00e-120	424.00
IUUC-Lch-050600	Latimeria chalumnae	95.35	7.00e-148	515.00
IUUC-Lpe-051540	Leersia perrieri	44.72	5.00e-62	229.00
IUUC-Loc-052509	Lepisosteus oculatus	94.96	3.00e-145	506.00
IUUC-Lma-053103	Leptosphaeria maculans	30.80	2.00e-32	131.00
IUUC-Laf-053527	Loxodonta africana	98.84	3.00e-152	529.00
IUUC-Mcc-055699	Macaca mulatta	89.55	2.00e-146	510.00
IUUC-Meu-056626	Macropus eugenii	78.29	2.00e-112	397.00
IUUC-Mor-056909	Magnaporthe oryzae	29.08	1.00e-25	109.00
IUUC-Mpo-057299	Magnaporthe poae	24.64	2.00e-17	82.00
IUUC-Mtr-057964	Medicago truncatula	41.46	4.00e-57	213.00
IUUC-Mla-058990	Melampsora laricipopulina	28.98	2.00e-19	89.00
IUUC-Mga-059379	Meleagris gallopavo	98.28	5.00e-136	475.00
IUUC-Mvi-060312	Microbotryum violaceum	33.85	8.00e-42	162.00
IUUC-Mmr-060851	Microcebus murinus	99.61	1.00e-152	530.00
IUUC-Mdo-063074	Monodelphis domestica	98.84	4.00e-155	541.00
IUUC-Mmu-063954	Mus musculus	98.84	5.00e-152	529.00
IUUC-Mac-065016	Musa acuminata	46.71	1.00e-43	168.00
IUUC-Mpu-066870	Mustela putorius furo	99.59	6.00e-145	505.00
IUUC-Mlu-067701	Myotis lucifugus	99.22	5.00e-152	529.00
IUUC-Ncr-068780	Neurospora crassa	25.45	7.00e-24	103.00
IUUC-Nle-069291	Nomascus leucogenys	99.61	5.00e-153	532.00
IUUC-Opr-070265	Ochotona princeps	72.87	7.00e-96	342.00
IUUC-Ont-071408	Oreochromis niloticus	89.15	1.00e-135	474.00
IUUC-Ocu-074648	Oryctolagus cuniculus	99.61	7.00e-153	531.00
IUUC-Oba-074993	Oryza barthii	44.72	4.00e-62	230.00
IUUC-Obr-076341	Oryza brachyantha	44.31	2.00e-62	231.00
IUUC-Ogl-077099	Oryza glaberrima	44.72	4.00e-62	230.00
IUUC-Ogu-078285	Oryza glumaepatula	44.31	8.00e-61	226.00
IUUC-Oin-079441	Oryza indica	44.72	5.00e-62	229.00
IUUC-Olo-081037	Oryza longistaminata	44.72	5.00e-62	229.00
IUUC-Ome-081357	Oryza meridionalis	44.72	5.00e-62	229.00
IUUC-Oni-082632	Oryza nivara	44.31	5.00e-62	229.00
IUUC-Opu-083351	Oryza punctata	44.40	6.00e-58	216.00
IUUC-Oru-084306	Oryza rufipogon	44.72	5.00e-62	229.00
IUUC-Osa-085307	Oryza sativa	44.72	5.00e-62	229.00
IUUC-Ola-086371	Oryzias latipes	84.50	3.00e-134	469.00
IUUC-Olu-087646	Ostreococcus lucimarinus	36.44	9.00e-45	172.00
IUUC-Oga-089015	Otolemur garnettii	99.22	2.00e-152	530.00
IUUC-Oar-090405	Ovis aries	99.22	2.00e-152	530.00
IUUC-Ptr-090735	Pan troglodytes	99.61	7.00e-153	531.00
IUUC-Pan-092186	Papio anubis	98.84	2.00e-149	520.00
IUUC-Psi-093110	Pelodiscus sinensis	98.77	3.00e-143	499.00
IUUC-Ppa-095306	Physcomitrella patens	43.55	2.00e-58	218.00
IUUC-Pfo-096813	Poecilia formosa	82.09	1.00e-132	464.00
IUUC-Pca-100218	Procavia capensis	95.74	2.00e-149	520.00
IUUC-Ppe-102032	Prunus persica	43.55	1.00e-60	225.00
IUUC-Pva-102983	Pteropus vampyrus	93.80	2.00e-138	483.00
IUUC-Pgr-103633	Puccinia graminis	27.87	4.00e-25	107.00
IUUC-Ptt-103979	Puccinia triticina	38.81	1.00e-04	40.40
IUUC-Pyt-104428	Pyrenophora triticirepentis	30.56	1.00e-29	122.00
IUUC-Rno-105554	Rattus norvegicus	98.45	4.00e-152	529.00
IUUC-Sce-106358	Saccharomyces cerevisiae	24.81	4.00e-20	90.90
IUUC-Sha-106888	Sarcophilus harrisii	99.22	1.00e-152	531.00
IUUC-Sja-107938	Schizosaccharomyces japonicus	30.65	5.00e-23	100.00
IUUC-Spo-108207	Schizosaccharomyces pombe	31.94	1.00e-24	105.00
IUUC-Ssl-108410	Sclerotinia sclerotiorum	32.95	2.00e-32	132.00
IUUC-Smo-108750	Selaginella moellendorffii	42.28	4.00e-50	190.00
IUUC-Sit-110052	Setaria italica	43.55	5.00e-62	229.00
IUUC-Sly-111489	Solanum lycopersicum	45.12	1.00e-60	225.00
IUUC-Stu-112517	Solanum tuberosum	43.32	3.00e-59	220.00
IUUC-Sar-113509	Sorex araneus	75.97	7.00e-107	379.00
IUUC-Sbi-114113	Sorghum bicolor	43.55	4.00e-62	230.00
IUUC-Sre-115221	Sporisorium reilianum	28.08	6.00e-26	110.00
IUUC-Ssc-115547	Sus scrofa	99.61	5.00e-153	532.00
IUUC-Tgu-117147	Taeniopygia guttata	98.45	1.00e-151	527.00
IUUC-Tru-117740	Takifugu rubripes	86.43	2.00e-133	467.00
IUUC-Tsy-119599	Tarsius syrichta	99.22	2.00e-152	530.00
IUUC-Tni-120315	Tetraodon nigroviridis	81.64	2.00e-130	457.00
IUUC-Tca-121033	Theobroma cacao	43.50	9.00e-59	219.00
IUUC-Tvi-122607	Trichoderma virens	28.95	7.00e-26	110.00
IUUC-Tae-125740	Triticum aestivum	37.28	1.00e-54	206.00
IUUC-Tur-126375	Triticum urartu	34.15	2.00e-51	195.00
IUUC-Tme-126878	Tuber melanosporum	33.60	4.00e-39	154.00
IUUC-Ttr-129086	Tursiops truncatus	88.76	6.00e-132	462.00
IUUC-Uma-129364	Ustilago maydis	30.03	2.00e-34	139.00
IUUC-Vpa-130048	Vicugna pacos	87.21	4.00e-128	449.00
IUUC-Vvi-130834	Vitis vinifera	43.90	2.00e-59	221.00
IUUC-Xtr-131888	Xenopus tropicalis	98.84	1.00e-151	527.00
IUUC-Xma-133580	Xiphophorus maculatus	84.50	5.00e-134	469.00
IUUC-Yli-134595	Yarrowia lipolytica	32.51	2.00e-36	144.00
IUUC-Zma-135642	Zea mays	44.49	9.00e-62	229.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence