iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-073907

Ensembl Protein ID

ENSOCUP00000011394.2

UniProt Accession

G1T504; G1T504_RABIT

Genbank Protein ID

ENSOCUP00000011394

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AAGW02010949

Gene Name

BLK

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000013226.3	ENSOCUT00000013236.3	ENSOCUP00000011394.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.10e-13	51.0	56	112

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           + v +lydy a+nd +L + +G++++++   ++ ++W+ + +  +gk+G +P+nFv+ +e
   Q: 56   HFVVALYDYAAVNDQDLHMVRGEKLQIL---QETGDWWLARSLVTGKEGYVPSNFVAGVE 112
           5689************************...78899********************9876 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MGLVGSKKQV KEKGKSHWSP ATVSAQSKAP PPLPPLVVLN HLDPPPPSEL PEQEGHFVVA 60
LYDYAAVNDQ DLHMVRGEKL QILQETGDWW LARSLVTGKE GYVPSNFVAG VESLEVEKWF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGAGCACCA AATTTGGGGC CTGCCACTCT CACCCCATCA TTCAATGTTC ACAGCATCCT 60
GTGAGCCAGC TATTATTAGC ATCATTTAAA AGACAAAACC AAGTCAACAA GGCTGAGAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0050853--P:B cell receptor signaling pathway
GO:0032024--P:positive regulation of insulin secretion

KEGG

ocu:100345996

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002133	Ailuropoda melanoleuca	87.20	0.00e+00	878.00
IUUC-Apl-003307	Anas platyrhynchos	76.12	0.00e+00	740.00
IUUC-Aca-004357	Anolis carolinensis	70.11	0.00e+00	673.00
IUUC-Ame-010642	Astyanax mexicanus	71.91	0.00e+00	690.00
IUUC-Bta-012400	Bos taurus	86.43	0.00e+00	879.00
IUUC-Cfa-021056	Canis familiaris	86.80	0.00e+00	888.00
IUUC-Cpo-021779	Cavia porcellus	86.00	0.00e+00	868.00
IUUC-Csa-023557	Chlorocebus sabaeus	86.93	0.00e+00	888.00
IUUC-Dre-027517	Danio rerio	71.71	0.00e+00	699.00
IUUC-Eca-034218	Equus caballus	87.99	0.00e+00	867.00
IUUC-Eeu-035095	Erinaceus europaeus	64.60	0.00e+00	631.00
IUUC-Fca-036015	Felis catus	86.00	0.00e+00	884.00
IUUC-Fal-036946	Ficedula albicollis	75.28	0.00e+00	726.00
IUUC-Gmo-038861	Gadus morhua	67.57	0.00e+00	634.00
IUUC-Gga-040822	Gallus gallus	71.57	0.00e+00	744.00
IUUC-Ggo-044608	Gorilla gorilla	88.73	0.00e+00	807.00
IUUC-Hsa-046719	Homo sapiens	85.74	0.00e+00	873.00
IUUC-Itr-048323	Ictidomys tridecemlineatus	87.00	0.00e+00	868.00
IUUC-Lch-050114	Latimeria chalumnae	72.54	0.00e+00	699.00
IUUC-Loc-052326	Lepisosteus oculatus	67.00	0.00e+00	711.00
IUUC-Laf-053387	Loxodonta africana	84.80	0.00e+00	867.00
IUUC-Mcc-055026	Macaca mulatta	86.34	0.00e+00	883.00
IUUC-Mga-059427	Meleagris gallopavo	76.01	0.00e+00	728.00
IUUC-Mmr-061660	Microcebus murinus	87.40	0.00e+00	880.00
IUUC-Mdo-062318	Monodelphis domestica	75.75	0.00e+00	798.00
IUUC-Mmu-063325	Mus musculus	85.40	0.00e+00	877.00
IUUC-Mpu-066582	Mustela putorius furo	87.20	0.00e+00	878.00
IUUC-Nle-069624	Nomascus leucogenys	87.22	0.00e+00	860.00
IUUC-Opr-070656	Ochotona princeps	89.60	0.00e+00	874.00
IUUC-Ont-072266	Oreochromis niloticus	66.14	0.00e+00	689.00
IUUC-Ola-086668	Oryzias latipes	71.85	0.00e+00	674.00
IUUC-Oga-088057	Otolemur garnettii	86.03	0.00e+00	879.00
IUUC-Oar-089332	Ovis aries	82.04	0.00e+00	835.00
IUUC-Ptr-091551	Pan troglodytes	83.95	0.00e+00	827.00
IUUC-Pan-092173	Papio anubis	86.53	0.00e+00	864.00
IUUC-Psi-093895	Pelodiscus sinensis	73.32	0.00e+00	731.00
IUUC-Pfo-096608	Poecilia formosa	70.63	0.00e+00	688.00
IUUC-Pab-097598	Pongo abelii	87.60	0.00e+00	848.00
IUUC-Pva-102135	Pteropus vampyrus	87.85	0.00e+00	860.00
IUUC-Rno-104891	Rattus norvegicus	85.60	0.00e+00	865.00
IUUC-Sha-107192	Sarcophilus harrisii	77.34	0.00e+00	804.00
IUUC-Ssc-115696	Sus scrofa	86.63	0.00e+00	889.00
IUUC-Tgu-117056	Taeniopygia guttata	74.10	0.00e+00	718.00
IUUC-Tru-117621	Takifugu rubripes	70.09	0.00e+00	664.00
IUUC-Tbe-127520	Tupaia belangeri	86.28	0.00e+00	660.00
IUUC-Ttr-128457	Tursiops truncatus	85.63	0.00e+00	884.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence