iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020780

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03009812

Gene Name

CDC20

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000005259.3	ENSCAFT00000008495.3	ENSCAFP00000007875.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.10e-30	103.2	307	336
E3 adaptor/Cullin RING/APC_C/CDC20	4.10e-147	489.6	172	478

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvW 28
           gH+ +v++l++ +d ++l+sG++D+ + vW
   Q: 307  GHSQEVCGLRWaPDgRHLASGGNDNLVNVW 336
           8***********999*************** PP

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+++ldape+r+d+ylnL+dWss nvlavaL++svylwsa++gd+ +l ++ +++++++sv+wi+eg++lavGt+++ev+++Dv+++k+
   Q: 172  PDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNSVYLWSASSGDILQLLQMeQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKR 260
           689************************************************899*********************************** PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdassse....Plk 173
           +r++tghsarv++L Wn+++lssGsr+g+i+h+dvrv+e++++tl++h+qevCGl+w+ d+++LasGGnDn v+vw ++  e    Pl+
   Q: 261  LRNMTGHSARVSSLCWNSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEggwvPLQ 349
           ********************************************************************************9999***** PP
   S: 174  kfkehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvae 262
           +f++h++avka+aw+Pwq+++La+GGGt+Dr+i++wn+++ga+l+++d++sqvcs+lws+++kel+s+hGfa+n++++wkyp+++kvae
   Q: 350  TFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAQSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAE 438
           ***************************************************************************************** PP
   S: 263  lkgheaRvlslalspdgeaivtaagDetlrfwklfdkkka 302
           lkgh+aRvlsl++spdg+++++aa+Detlr+w++f+ ++a
   Q: 439  LKGHTARVLSLTMSPDGATVASAAADETLRLWRCFELDPA 478
           ***********************************99876 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MAQFVFESDL HSLLQLDAPI PNAPPARWQR KAREAAGPAP SPMRAANRSH SAGRTPGRTP 60
GKSSSKAQTT PSKPGGDRYI PHRSASQMEV ASFLLSKENQ PEESHTPTKK EHQKAWALNL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GACTCGGCGG GCACCGCGTC CATGGCGCAG TTCGTGTTCG AGAGCGACCT GCACTCGCTG 60
CTGCAGCTGG ACGCGCCCAT CCCCAATGCG CCCCCCGCGC GCTGGCAGCG CAAGGCCAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033187--CDC20
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0007064--P:mitotic sister chromatid cohesion
GO:0090307--P:mitotic spindle assembly
GO:0090129--P:positive regulation of synapse maturation
GO:0031915--P:positive regulation of synaptic plasticity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity
GO:0040020--P:regulation of meiotic nuclear division

KEGG

cfa:100855774

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000638	Aegilops tauschii	46.55	8.00e-111	394.00
IUUC-Aml-001545	Ailuropoda melanoleuca	98.00	0.00e+00	954.00
IUUC-Atr-003103	Amborella trichopoda	46.68	8.00e-109	387.00
IUUC-Apl-003255	Anas platyrhynchos	79.55	0.00e+00	746.00
IUUC-Aca-004920	Anolis carolinensis	76.62	0.00e+00	782.00
IUUC-Aly-006012	Arabidopsis lyrata	48.77	4.00e-109	388.00
IUUC-Ath-006795	Arabidopsis thaliana	46.71	2.00e-107	382.00
IUUC-Ate-010479	Aspergillus terreus	50.78	7.00e-92	331.00
IUUC-Ame-010850	Astyanax mexicanus	60.70	5.00e-91	327.00
IUUC-Bgr-012059	Blumeria graminis	49.84	3.00e-95	342.00
IUUC-Bta-012625	Bos taurus	97.19	0.00e+00	946.00
IUUC-Bci-013607	Botrytis cinerea	47.95	1.00e-98	353.00
IUUC-Bdi-014344	Brachypodium distachyon	47.75	7.00e-110	390.00
IUUC-Bol-015368	Brassica oleracea	46.34	6.00e-106	379.00
IUUC-Bra-016738	Brassica rapa	46.36	2.00e-105	376.00
IUUC-Cja-019132	Callithrix jacchus	96.39	0.00e+00	942.00
IUUC-Cpo-022223	Cavia porcellus	96.39	0.00e+00	892.00
IUUC-Cre-022701	Chlamydomonas reinhardtii	50.47	5.00e-118	417.00
IUUC-Csa-023666	Chlorocebus sabaeus	97.19	0.00e+00	945.00
IUUC-Cho-024920	Choloepus hoffmanni	96.10	2.00e-160	558.00
IUUC-Cin-025675	Ciona intestinalis	50.60	2.00e-134	472.00
IUUC-Csv-026019	Ciona savignyi	51.13	6.00e-131	461.00
IUUC-Cgl-026465	Colletotrichum gloeosporioides	40.56	2.00e-96	347.00
IUUC-Cme-027234	Cyanidioschyzon merolae	51.91	7.00e-105	374.00
IUUC-Dre-028026	Danio rerio	60.16	0.00e+00	631.00
IUUC-Dno-028865	Dasypus novemcinctus	96.40	0.00e+00	933.00
IUUC-Dor-030958	Dipodomys ordii	95.79	0.00e+00	937.00
IUUC-Dse-031391	Dothistroma septosporum	49.10	1.00e-96	347.00
IUUC-Dme-031905	Drosophila melanogaster	49.91	8.00e-144	503.00
IUUC-Ete-032387	Echinops telfairi	91.58	0.00e+00	899.00
IUUC-Eca-033522	Equus caballus	86.77	0.00e+00	845.00
IUUC-Eeu-035059	Erinaceus europaeus	83.80	0.00e+00	785.00
IUUC-Fca-036346	Felis catus	97.96	0.00e+00	868.00
IUUC-Fal-037558	Ficedula albicollis	79.56	0.00e+00	790.00
IUUC-Fox-037850	Fusarium oxysporum	46.81	3.00e-97	348.00
IUUC-Fso-038375	Fusarium solani	48.68	9.00e-98	350.00
IUUC-Gmo-039284	Gadus morhua	61.90	1.00e-180	625.00
IUUC-Ggr-039864	Gaeumannomyces graminis	48.84	9.00e-100	357.00
IUUC-Gga-040790	Gallus gallus	78.74	0.00e+00	808.00
IUUC-Gac-041431	Gasterosteus aculeatus	61.23	3.00e-179	621.00
IUUC-Gma-043489	Glycine max	46.60	9.00e-107	380.00
IUUC-Ggo-045052	Gorilla gorilla	97.60	0.00e+00	947.00
IUUC-Hsa-046305	Homo sapiens	97.60	0.00e+00	947.00
IUUC-Hvu-047476	Hordeum vulgare	45.80	3.00e-110	392.00
IUUC-Itr-048461	Ictidomys tridecemlineatus	96.79	0.00e+00	897.00
IUUC-Lch-050174	Latimeria chalumnae	61.39	3.00e-174	604.00
IUUC-Lpe-050954	Leersia perrieri	48.33	1.00e-101	363.00
IUUC-Loc-052638	Lepisosteus oculatus	63.12	0.00e+00	630.00
IUUC-Lma-052998	Leptosphaeria maculans	43.27	5.00e-100	358.00
IUUC-Laf-053742	Loxodonta africana	97.39	0.00e+00	945.00
IUUC-Mcc-054948	Macaca mulatta	97.19	0.00e+00	945.00
IUUC-Meu-056013	Macropus eugenii	85.16	1.00e-140	493.00
IUUC-Mor-057277	Magnaporthe oryzae	52.48	3.00e-97	349.00
IUUC-Mpo-057624	Magnaporthe poae	51.79	7.00e-98	351.00
IUUC-Mtr-057725	Medicago truncatula	45.80	3.00e-100	358.00
IUUC-Mga-060102	Meleagris gallopavo	78.97	0.00e+00	809.00
IUUC-Mmr-061615	Microcebus murinus	97.49	0.00e+00	942.00
IUUC-Mdo-061982	Monodelphis domestica	88.89	0.00e+00	776.00
IUUC-Mmu-063864	Mus musculus	94.39	0.00e+00	929.00
IUUC-Mac-064861	Musa acuminata	47.46	3.00e-110	391.00
IUUC-Mpu-066502	Mustela putorius furo	98.00	0.00e+00	944.00
IUUC-Mlu-067277	Myotis lucifugus	88.82	0.00e+00	876.00
IUUC-Ncr-068951	Neurospora crassa	45.33	6.00e-95	341.00
IUUC-Nle-070149	Nomascus leucogenys	97.19	0.00e+00	940.00
IUUC-Opr-070778	Ochotona princeps	94.43	0.00e+00	681.00
IUUC-Ont-071660	Oreochromis niloticus	60.76	3.00e-177	614.00
IUUC-Oan-073677	Ornithorhynchus anatinus	76.49	0.00e+00	699.00
IUUC-Ocu-073797	Oryctolagus cuniculus	96.38	0.00e+00	937.00
IUUC-Oba-075514	Oryza barthii	48.10	3.00e-101	362.00
IUUC-Obr-076018	Oryza brachyantha	47.06	3.00e-109	388.00
IUUC-Ogl-077254	Oryza glaberrima	48.10	1.00e-101	363.00
IUUC-Ogu-078521	Oryza glumaepatula	48.40	3.00e-108	386.00
IUUC-Oin-080094	Oryza indica	48.10	1.00e-101	363.00
IUUC-Olo-080449	Oryza longistaminata	48.10	7.00e-102	363.00
IUUC-Ome-081186	Oryza meridionalis	47.98	2.00e-108	387.00
IUUC-Oni-082243	Oryza nivara	48.10	1.00e-101	363.00
IUUC-Opu-084007	Oryza punctata	48.10	4.00e-101	361.00
IUUC-Oru-084562	Oryza rufipogon	48.40	4.00e-108	385.00
IUUC-Osa-086094	Oryza sativa	48.10	1.00e-101	363.00
IUUC-Ola-086907	Oryzias latipes	60.63	4.00e-165	574.00
IUUC-Olu-087647	Ostreococcus lucimarinus	48.31	1.00e-118	420.00
IUUC-Oga-088184	Otolemur garnettii	95.80	0.00e+00	929.00
IUUC-Oar-090023	Ovis aries	92.08	0.00e+00	840.00
IUUC-Ptr-090935	Pan troglodytes	96.83	0.00e+00	881.00
IUUC-Pan-091845	Papio anubis	97.19	0.00e+00	945.00
IUUC-Psi-093188	Pelodiscus sinensis	80.16	0.00e+00	835.00
IUUC-Pma-094187	Petromyzon marinus	54.56	2.00e-149	522.00
IUUC-Pno-094809	Phaeosphaeria nodorum	42.46	6.00e-101	361.00
IUUC-Ppa-095457	Physcomitrella patens	47.66	4.00e-112	398.00
IUUC-Pfo-097429	Poecilia formosa	58.57	7.00e-161	560.00
IUUC-Pab-098603	Pongo abelii	97.39	0.00e+00	946.00
IUUC-Pop-099654	Populus trichocarpa	46.15	8.00e-103	367.00
IUUC-Pca-101062	Procavia capensis	96.39	0.00e+00	922.00
IUUC-Ppe-101865	Prunus persica	46.53	4.00e-96	345.00
IUUC-Pva-102925	Pteropus vampyrus	95.59	0.00e+00	965.00
IUUC-Pte-104142	Pyrenophora teres	42.42	2.00e-98	353.00
IUUC-Pyt-104693	Pyrenophora triticirepentis	42.42	2.00e-98	353.00
IUUC-Rno-106005	Rattus norvegicus	94.59	0.00e+00	929.00
IUUC-Sha-107472	Sarcophilus harrisii	90.00	0.00e+00	895.00
IUUC-Sja-107919	Schizosaccharomyces japonicus	42.34	1.00e-93	336.00
IUUC-Spo-108075	Schizosaccharomyces pombe	44.72	7.00e-97	347.00
IUUC-Ssl-108507	Sclerotinia sclerotiorum	49.27	5.00e-98	351.00
IUUC-Smo-108922	Selaginella moellendorffii	48.60	2.00e-122	432.00
IUUC-Sit-110732	Setaria italica	47.36	4.00e-110	391.00
IUUC-Sly-111202	Solanum lycopersicum	44.16	5.00e-106	377.00
IUUC-Stu-112024	Solanum tuberosum	42.76	3.00e-106	378.00
IUUC-Sar-113092	Sorex araneus	91.18	0.00e+00	879.00
IUUC-Sbi-114558	Sorghum bicolor	46.46	3.00e-110	392.00
IUUC-Ssc-115710	Sus scrofa	97.60	0.00e+00	949.00
IUUC-Tgu-117100	Taeniopygia guttata	78.57	0.00e+00	790.00
IUUC-Tru-118184	Takifugu rubripes	56.88	4.00e-138	484.00
IUUC-Tsy-118892	Tarsius syrichta	96.10	7.00e-162	562.00
IUUC-Tni-120474	Tetraodon nigroviridis	58.96	1.00e-167	582.00
IUUC-Tca-120949	Theobroma cacao	46.14	5.00e-106	377.00
IUUC-Tre-122211	Trichoderma reesei	40.49	4.00e-97	348.00
IUUC-Tvi-122531	Trichoderma virens	41.28	2.00e-98	353.00
IUUC-Tae-123017	Triticum aestivum	45.88	1.00e-110	393.00
IUUC-Tur-126193	Triticum urartu	46.02	2.00e-110	392.00
IUUC-Tbe-127384	Tupaia belangeri	97.31	9.00e-175	606.00
IUUC-Ttr-128511	Tursiops truncatus	97.19	0.00e+00	942.00
IUUC-Vda-129993	Verticillium dahliae	40.39	1.00e-97	350.00
IUUC-Vvi-131245	Vitis vinifera	46.17	3.00e-94	338.00
IUUC-Xtr-131993	Xenopus tropicalis	72.51	0.00e+00	747.00
IUUC-Xma-133332	Xiphophorus maculatus	61.74	2.00e-177	615.00
IUUC-Zma-135135	Zea mays	47.41	1.00e-107	383.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence