iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012693

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin-conjugating enzyme E2 L3

Genbank Nucleotide ID

DAAA02045728

Gene Name

UBE2L3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000013038.5	ENSBTAT00000017332.5	ENSBTAP00000017332.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	8.10e-42	142.4	1	133

Active Site

Position(s)	Description	Evidence
78	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 4    kelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekW 92
           +el+e++k  +++++  +vde++l +w+ li+ p++ pY++g+F++ei+fp +YPfkPPk++f tki+hPn++e+G+vCl ++ ++e+W
   Q: 1    QELEEIRKCGMKNFRNIQVDEANLLTWQGLIV-PDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVI-SAENW 87
           6999****************************.**************************************************.5**** PP
   S: 93   spalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           +pa++  +v+ s+++l+++p+pe+pl+++ ae+++k+r+++ k+++
   Q: 88   KPATKTDQVIQSLIALVNDPQPEHPLRADLAEEYSKDRKKFCKNAE 133
           ******************************************9986 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

QELEEIRKCG MKNFRNIQVD EANLLTWQGL IVPDNPPYDK GAFRIEINFP AEYPFKPPKI 60
TFKTKIYHPN IDEKGQVCLP VISAENWKPA TKTDQVIQSL IALVNDPQPE HPLRADLAEE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGAGCTTG AAGAAATCCG CAAGTGTGGG ATGAAAAACT TCCGTAACAT CCAGGTCGAT 60
GAAGCTAATT TGCTGACTTG GCAAGGGCTC ATTGTTCCCG TGAGTACTGG ACAGCTCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001446	Ailuropoda melanoleuca	100.00	2.00e-52	197.00
IUUC-Apl-003318	Anas platyrhynchos	100.00	7.00e-73	265.00
IUUC-Aca-005234	Anolis carolinensis	100.00	4.00e-73	266.00
IUUC-Ame-011452	Astyanax mexicanus	95.21	2.00e-68	251.00
IUUC-Cel-018332	Caenorhabditis elegans	58.33	2.00e-54	204.00
IUUC-Cja-019062	Callithrix jacchus	99.32	8.00e-73	265.00
IUUC-Cfa-020027	Canis familiaris	99.32	8.00e-73	265.00
IUUC-Cpo-022341	Cavia porcellus	99.32	8.00e-73	265.00
IUUC-Cho-024916	Choloepus hoffmanni	91.49	1.00e-37	147.00
IUUC-Cin-025130	Ciona intestinalis	65.75	4.00e-43	166.00
IUUC-Csv-026183	Ciona savignyi	65.73	3.00e-44	170.00
IUUC-Dre-027710	Danio rerio	94.52	6.00e-69	252.00
IUUC-Dno-029371	Dasypus novemcinctus	100.00	1.00e-54	204.00
IUUC-Dor-031017	Dipodomys ordii	93.84	8.00e-66	242.00
IUUC-Dme-031814	Drosophila melanogaster	73.97	3.00e-65	240.00
IUUC-Ete-032754	Echinops telfairi	99.32	8.00e-73	265.00
IUUC-Eca-034188	Equus caballus	100.00	6.00e-73	265.00
IUUC-Eeu-034942	Erinaceus europaeus	97.95	8.00e-72	262.00
IUUC-Fca-036173	Felis catus	99.32	8.00e-73	265.00
IUUC-Fal-036820	Ficedula albicollis	100.00	1.00e-72	265.00
IUUC-Gmo-038480	Gadus morhua	91.03	5.00e-65	239.00
IUUC-Gga-041039	Gallus gallus	99.32	8.00e-73	265.00
IUUC-Gac-041571	Gasterosteus aculeatus	78.08	2.00e-54	204.00
IUUC-Ggo-044482	Gorilla gorilla	99.32	2.00e-72	263.00
IUUC-Hsa-046287	Homo sapiens	99.32	8.00e-73	265.00
IUUC-Itr-049057	Ictidomys tridecemlineatus	100.00	1.00e-66	244.00
IUUC-Lch-049699	Latimeria chalumnae	81.90	2.00e-43	167.00
IUUC-Loc-052000	Lepisosteus oculatus	92.57	6.00e-67	246.00
IUUC-Laf-053833	Loxodonta africana	100.00	1.00e-72	264.00
IUUC-Mcc-054660	Macaca mulatta	100.00	7.00e-71	259.00
IUUC-Meu-056738	Macropus eugenii	98.95	2.00e-42	163.00
IUUC-Mga-060134	Meleagris gallopavo	97.95	6.00e-70	256.00
IUUC-Mmr-061002	Microcebus murinus	100.00	4.00e-72	263.00
IUUC-Mdo-062043	Monodelphis domestica	81.01	7.00e-68	249.00
IUUC-Mmu-063615	Mus musculus	99.32	8.00e-73	265.00
IUUC-Mlu-066971	Myotis lucifugus	100.00	7.00e-73	265.00
IUUC-Nle-070093	Nomascus leucogenys	99.32	2.00e-72	263.00
IUUC-Opr-070315	Ochotona princeps	99.32	8.00e-73	265.00
IUUC-Ont-072036	Oreochromis niloticus	92.47	5.00e-67	246.00
IUUC-Ocu-074565	Oryctolagus cuniculus	100.00	3.00e-73	266.00
IUUC-Ola-086994	Oryzias latipes	86.30	3.00e-72	263.00
IUUC-Oga-088173	Otolemur garnettii	95.86	9.00e-68	248.00
IUUC-Oar-089520	Ovis aries	100.00	7.00e-73	265.00
IUUC-Ptr-090890	Pan troglodytes	98.63	1.00e-82	298.00
IUUC-Pan-092445	Papio anubis	99.32	2.00e-72	263.00
IUUC-Psi-093376	Pelodiscus sinensis	100.00	1.00e-72	265.00
IUUC-Pma-094445	Petromyzon marinus	82.44	5.00e-53	199.00
IUUC-Pfo-096258	Poecilia formosa	92.47	1.00e-66	244.00
IUUC-Pab-097654	Pongo abelii	99.32	8.00e-73	265.00
IUUC-Pca-100712	Procavia capensis	77.40	4.00e-50	189.00
IUUC-Pva-103113	Pteropus vampyrus	100.00	2.00e-72	263.00
IUUC-Sha-106823	Sarcophilus harrisii	100.00	7.00e-70	255.00
IUUC-Sar-113240	Sorex araneus	100.00	2.00e-72	263.00
IUUC-Ssc-115442	Sus scrofa	99.32	8.00e-73	265.00
IUUC-Tgu-117352	Taeniopygia guttata	100.00	6.00e-73	265.00
IUUC-Tru-117653	Takifugu rubripes	93.15	1.00e-67	248.00
IUUC-Tsy-119345	Tarsius syrichta	100.00	1.00e-52	198.00
IUUC-Tni-119709	Tetraodon nigroviridis	93.15	1.00e-67	248.00
IUUC-Tbe-127294	Tupaia belangeri	98.63	3.00e-71	260.00
IUUC-Ttr-128840	Tursiops truncatus	99.32	8.00e-73	265.00
IUUC-Xtr-132650	Xenopus tropicalis	96.58	1.00e-70	258.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence