iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-021593

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02016080

Gene Name

KLHL25

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000013099.3	ENSCPOT00000013226.2	ENSCPOP00000011791.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	3.80e-20	72.0	46	114
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	5.30e-08	32.1	147	177

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd.vqpevfrallkFlYtgkldene 69
           +Dv+l  g++ f++h++vLaasS++F+a+f+++l+es+  ++v+++d + pev++ ll+F Y++++ +ne
   Q: 46   TDVTLWAGDRAFPCHRAVLAASSRYFEAMFSHGLRESR-DDTVNFQDnLHPEVLELLLDFAYSSRIAINE 114
           7*************************************.*******99*****************99987 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhFk 32
           +Nclg++ ++d+++c++L+++  +++l hF+
   Q: 147  SNCLGMMLLSDAHQCRRLHQFSWRMCLEHFE 177
           8****************************95 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MSVSVHETRK SRSSTGSMNI TLFHKASHPD SVLAQLNTLR KQRMFTDVTL WAGDRAFPCH 60
RAVLAASSRY FEAMFSHGLR ESRDDTVNFQ DNLHPEVLEL LLDFAYSSRI AINEENAESL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGGTCA GCGTCCATGA GACCCGCAAG TCGCGGAGCA GCACGGGCTC CATGAACATC 60
ACCCTCTTCC ACAAGGCCTC GCACCCGGAC TCTGTGCTGG CCCAGCTCAA CACATTGCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030565--KLHL25
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0006446--P:regulation of translational initiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002373	Ailuropoda melanoleuca	93.55	0.00e+00	1149.00
IUUC-Apl-003543	Anas platyrhynchos	86.95	0.00e+00	1046.00
IUUC-Aca-004729	Anolis carolinensis	84.38	0.00e+00	1031.00
IUUC-Ame-011020	Astyanax mexicanus	84.04	0.00e+00	1013.00
IUUC-Bta-012955	Bos taurus	92.53	0.00e+00	1141.00
IUUC-Cja-018839	Callithrix jacchus	93.04	0.00e+00	1143.00
IUUC-Cfa-020224	Canis familiaris	93.89	0.00e+00	1154.00
IUUC-Csa-023276	Chlorocebus sabaeus	93.72	0.00e+00	1150.00
IUUC-Dre-028053	Danio rerio	84.38	0.00e+00	987.00
IUUC-Dno-029287	Dasypus novemcinctus	91.68	0.00e+00	1130.00
IUUC-Dor-030908	Dipodomys ordii	85.74	0.00e+00	1032.00
IUUC-Fca-035897	Felis catus	93.55	0.00e+00	1147.00
IUUC-Fal-037036	Ficedula albicollis	86.93	0.00e+00	1049.00
IUUC-Gmo-039345	Gadus morhua	83.87	0.00e+00	984.00
IUUC-Gga-040404	Gallus gallus	86.76	0.00e+00	1051.00
IUUC-Gac-042447	Gasterosteus aculeatus	83.87	0.00e+00	1000.00
IUUC-Ggo-045060	Gorilla gorilla	93.55	0.00e+00	1149.00
IUUC-Hsa-046494	Homo sapiens	93.55	0.00e+00	1148.00
IUUC-Itr-047993	Ictidomys tridecemlineatus	93.89	0.00e+00	1154.00
IUUC-Lch-050211	Latimeria chalumnae	84.69	0.00e+00	1022.00
IUUC-Loc-052578	Lepisosteus oculatus	83.53	0.00e+00	1016.00
IUUC-Lma-053168	Leptosphaeria maculans	29.79	2.00e-05	43.10
IUUC-Laf-053498	Loxodonta africana	92.87	0.00e+00	1095.00
IUUC-Mcc-055033	Macaca mulatta	93.89	0.00e+00	1152.00
IUUC-Meu-056893	Macropus eugenii	88.79	0.00e+00	1093.00
IUUC-Mga-060025	Meleagris gallopavo	86.93	0.00e+00	1052.00
IUUC-Mmr-060658	Microcebus murinus	93.89	0.00e+00	1153.00
IUUC-Mdo-062667	Monodelphis domestica	89.13	0.00e+00	1101.00
IUUC-Mmu-063125	Mus musculus	91.51	0.00e+00	1097.00
IUUC-Mpu-066209	Mustela putorius furo	93.55	0.00e+00	1148.00
IUUC-Mlu-068237	Myotis lucifugus	92.53	0.00e+00	1110.00
IUUC-Nle-069454	Nomascus leucogenys	93.48	0.00e+00	1135.00
IUUC-Ont-072138	Oreochromis niloticus	83.87	0.00e+00	986.00
IUUC-Oan-073320	Ornithorhynchus anatinus	84.55	0.00e+00	1042.00
IUUC-Ocu-073765	Oryctolagus cuniculus	88.46	0.00e+00	1069.00
IUUC-Oga-088002	Otolemur garnettii	93.72	0.00e+00	1144.00
IUUC-Oar-089481	Ovis aries	92.36	0.00e+00	1141.00
IUUC-Ptr-091200	Pan troglodytes	93.72	0.00e+00	1152.00
IUUC-Psi-093884	Pelodiscus sinensis	86.42	0.00e+00	1044.00
IUUC-Pab-098588	Pongo abelii	81.83	0.00e+00	963.00
IUUC-Pva-102321	Pteropus vampyrus	93.55	0.00e+00	1149.00
IUUC-Rno-104835	Rattus norvegicus	91.00	0.00e+00	1094.00
IUUC-Sha-107528	Sarcophilus harrisii	88.29	0.00e+00	1090.00
IUUC-Ssc-116161	Sus scrofa	93.89	0.00e+00	1148.00
IUUC-Tgu-116569	Taeniopygia guttata	87.10	0.00e+00	1052.00
IUUC-Tni-120525	Tetraodon nigroviridis	75.80	0.00e+00	872.00
IUUC-Ttr-129297	Tursiops truncatus	94.06	0.00e+00	1153.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence