iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-088438

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03016885

Gene Name

SOCS2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000000104.2	ENSOGAT00000000104.2	ENSOGAP00000000092.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	2.20e-15	56.3	152	197

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 3    klwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
            +++l ++ +SLqhLCRl+I++c+ +     i++LPLP +LkdYL+++++q
   Q: 152  LTRPLYTSAPSLQHLCRLTINKCTST-----IWGLPLPTRLKDYLEEYKFQ 197
           5788999*******************.....8***************9886 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MTLRCLEPSG NGAEGTRSQW GTAGSTEEPS PEAARLAKAL RELGQTGWYW GSMTVNEAKE 60
KLKEAPEGTF LIRDSSHSDY LLTISVKTSA GPTNLRIEYQ EGKFRLDSII CVKSKLKQFD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGCAGTCAC CTGTCTTTGC CGCAGTGATA TTTATCCCAT GACCCTGCGG TGCCTGGAAC 60
CCTCCGGGAA TGGCGCGGAA GGGACGCGGA GCCAGTGGGG GACGGCGGGG TCAACGGAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028410--SOCS2
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

PRINTS

PR00401--SH2DOMAIN

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0060396--P:growth hormone receptor signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0016567--P:protein ubiquitination
GO:0001558--P:regulation of cell growth
GO:0032355--P:response to estradiol

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002075	Ailuropoda melanoleuca	95.45	7.00e-105	372.00
IUUC-Apl-003484	Anas platyrhynchos	79.08	6.00e-72	262.00
IUUC-Aca-004253	Anolis carolinensis	70.73	6.00e-71	259.00
IUUC-Ame-011267	Astyanax mexicanus	63.47	5.00e-60	223.00
IUUC-Bta-013183	Bos taurus	94.95	1.00e-99	355.00
IUUC-Cja-018862	Callithrix jacchus	96.46	1.00e-101	362.00
IUUC-Cfa-020226	Canis familiaris	93.91	5.00e-96	343.00
IUUC-Cpo-022414	Cavia porcellus	96.46	3.00e-105	373.00
IUUC-Csa-023758	Chlorocebus sabaeus	96.46	1.00e-105	374.00
IUUC-Cho-024471	Choloepus hoffmanni	86.84	2.00e-72	264.00
IUUC-Dre-028288	Danio rerio	56.99	2.00e-63	234.00
IUUC-Dno-029036	Dasypus novemcinctus	95.96	2.00e-106	377.00
IUUC-Dor-030447	Dipodomys ordii	97.35	1.00e-86	311.00
IUUC-Ete-033023	Echinops telfairi	92.93	4.00e-109	386.00
IUUC-Fca-036469	Felis catus	96.46	8.00e-101	358.00
IUUC-Fal-036642	Ficedula albicollis	72.84	6.00e-70	256.00
IUUC-Gmo-039331	Gadus morhua	60.58	6.00e-35	139.00
IUUC-Gga-040809	Gallus gallus	76.10	3.00e-72	263.00
IUUC-Gac-041398	Gasterosteus aculeatus	60.12	6.00e-59	219.00
IUUC-Ggo-045341	Gorilla gorilla	96.97	7.00e-102	362.00
IUUC-Hsa-046557	Homo sapiens	96.46	1.00e-113	401.00
IUUC-Itr-049013	Ictidomys tridecemlineatus	81.73	8.00e-93	332.00
IUUC-Lch-050160	Latimeria chalumnae	61.07	1.00e-49	188.00
IUUC-Loc-051825	Lepisosteus oculatus	55.73	1.00e-60	225.00
IUUC-Laf-053560	Loxodonta africana	94.44	5.00e-98	349.00
IUUC-Mcc-055890	Macaca mulatta	96.46	5.00e-101	359.00
IUUC-Meu-056218	Macropus eugenii	79.80	1.00e-95	342.00
IUUC-Mga-059755	Meleagris gallopavo	78.29	1.00e-70	258.00
IUUC-Mmr-061387	Microcebus murinus	96.46	1.00e-104	371.00
IUUC-Mdo-062383	Monodelphis domestica	80.81	2.00e-95	341.00
IUUC-Mmu-063443	Mus musculus	93.43	2.00e-101	360.00
IUUC-Mpu-066459	Mustela putorius furo	94.95	3.00e-99	353.00
IUUC-Mlu-068040	Myotis lucifugus	95.45	8.00e-106	375.00
IUUC-Nle-069016	Nomascus leucogenys	91.41	3.00e-98	350.00
IUUC-Opr-071087	Ochotona princeps	89.39	1.00e-103	368.00
IUUC-Ont-072340	Oreochromis niloticus	56.77	2.00e-60	224.00
IUUC-Oan-073443	Ornithorhynchus anatinus	78.28	1.00e-89	321.00
IUUC-Ocu-074539	Oryctolagus cuniculus	94.92	5.00e-99	353.00
IUUC-Ola-087004	Oryzias latipes	59.49	3.00e-55	207.00
IUUC-Oar-089932	Ovis aries	94.95	2.00e-99	354.00
IUUC-Ptr-091037	Pan troglodytes	96.97	7.00e-102	362.00
IUUC-Pan-092767	Papio anubis	96.46	4.00e-101	360.00
IUUC-Psi-093099	Pelodiscus sinensis	77.36	6.00e-74	269.00
IUUC-Pma-094671	Petromyzon marinus	47.71	8.00e-36	143.00
IUUC-Pfo-097073	Poecilia formosa	55.37	9.00e-56	209.00
IUUC-Pab-098319	Pongo abelii	96.46	4.00e-107	380.00
IUUC-Pca-101117	Procavia capensis	92.42	1.00e-98	351.00
IUUC-Pva-102117	Pteropus vampyrus	94.44	4.00e-97	346.00
IUUC-Rno-105913	Rattus norvegicus	92.93	6.00e-101	359.00
IUUC-Sha-106500	Sarcophilus harrisii	80.71	6.00e-94	336.00
IUUC-Ssc-115252	Sus scrofa	95.45	2.00e-104	370.00
IUUC-Tgu-117524	Taeniopygia guttata	74.84	2.00e-69	253.00
IUUC-Tsy-119335	Tarsius syrichta	93.38	2.00e-84	304.00
IUUC-Tni-120263	Tetraodon nigroviridis	54.26	1.00e-56	212.00
IUUC-Tbe-127915	Tupaia belangeri	93.94	5.00e-96	343.00
IUUC-Ttr-128372	Tursiops truncatus	94.95	8.00e-104	369.00
IUUC-Vpa-130422	Vicugna pacos	97.35	2.00e-86	310.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence