iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mcc-055045

UUCD1 version

UUC-MaM-00638

Ensembl Protein ID

ENSMMUP00000016558.3

UniProt Accession

H9ERN5; F7F5C0; H9ERN5_MACMU

Genbank Protein ID

AFE65044.1; AFH34663.1; AFI38785.1

Protein Name

Suppressor of cytokine signaling 6

Genbank Nucleotide ID

JSUE03019910; JU477859; JV048714

Gene Name

SOCS6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000012610.3	ENSMMUT00000017682.3	ENSMMUP00000016558.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	7.00e-17	62.1	488	535

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 2    sklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedy 52
            ++ +++ ++rSLq+LCR++Ir++++++ +   +kLPLP+++kdYL++++y
   Q: 488  TNPVSRFMQVRSLQYLCRFVIRQYTRIDLI---QKLPLPNKMKDYLQEKHY 535
           5788999********************888...***************997 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MKKISLKTLR KSFNLNKSKE ETDFMVVQQP SLASDFGKDD SLFGSCYGKD MASCDINGEE 60
EKGGKNRSKS ESLMGTLKRR LSAKQKPKGK AGTPSGSSAD EDTFSSSSAP IVFKDVRAQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATCCGCCTT GGTCTCCCAG AGTGGGATTA CAGACATGAG CCACCATGCC TGGTCTCTCA 60
GTTTTATTTT CTAGTAGAAT ACATTTCAAT AGACACAACC CACATAAACA ATGCTGCTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028421--SOCS6
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0001772--C:immunological synapse
GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0010498--P:proteasomal protein catabolic process
GO:0016567--P:protein ubiquitination
GO:0040008--P:regulation of growth

KEGG

mcc:704108

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001911	Ailuropoda melanoleuca	94.95	0.00e+00	946.00
IUUC-Atr-002940	Amborella trichopoda	27.27	7.30e-02	31.60
IUUC-Apl-004035	Anas platyrhynchos	89.91	0.00e+00	890.00
IUUC-Aca-004782	Anolis carolinensis	88.43	0.00e+00	858.00
IUUC-Ame-011790	Astyanax mexicanus	69.05	0.00e+00	642.00
IUUC-Bta-012579	Bos taurus	94.74	2.00e-108	385.00
IUUC-Bol-015843	Brassica oleracea	28.77	3.10e-02	33.10
IUUC-Cel-018643	Caenorhabditis elegans	33.59	1.00e-11	62.80
IUUC-Cja-019528	Callithrix jacchus	97.76	0.00e+00	1022.00
IUUC-Cfa-020678	Canis familiaris	94.21	0.00e+00	961.00
IUUC-Cpo-021947	Cavia porcellus	94.95	0.00e+00	998.00
IUUC-Csa-023935	Chlorocebus sabaeus	99.63	0.00e+00	1018.00
IUUC-Cho-024477	Choloepus hoffmanni	91.21	0.00e+00	955.00
IUUC-Cin-025413	Ciona intestinalis	68.24	3.00e-66	245.00
IUUC-Csv-026247	Ciona savignyi	67.47	5.00e-65	241.00
IUUC-Cne-026906	Cryptococcus neoformans	26.04	1.40e-01	31.60
IUUC-Dre-027636	Danio rerio	68.89	0.00e+00	639.00
IUUC-Dno-029048	Dasypus novemcinctus	93.46	0.00e+00	953.00
IUUC-Dor-030401	Dipodomys ordii	91.23	0.00e+00	918.00
IUUC-Ete-033116	Echinops telfairi	49.12	2.00e-58	219.00
IUUC-Eca-033825	Equus caballus	94.95	0.00e+00	925.00
IUUC-Fca-036253	Felis catus	93.64	0.00e+00	872.00
IUUC-Fal-037614	Ficedula albicollis	90.47	0.00e+00	894.00
IUUC-Fox-037898	Fusarium oxysporum	27.16	1.60e-02	33.10
IUUC-Gmo-038928	Gadus morhua	70.11	0.00e+00	680.00
IUUC-Gga-040177	Gallus gallus	89.72	0.00e+00	885.00
IUUC-Gac-042263	Gasterosteus aculeatus	71.27	0.00e+00	703.00
IUUC-Ggo-045288	Gorilla gorilla	98.32	0.00e+00	1005.00
IUUC-Hsa-046409	Homo sapiens	98.69	0.00e+00	1007.00
IUUC-Itr-048996	Ictidomys tridecemlineatus	93.46	0.00e+00	926.00
IUUC-Lch-050354	Latimeria chalumnae	83.58	0.00e+00	863.00
IUUC-Loc-052319	Lepisosteus oculatus	81.90	0.00e+00	827.00
IUUC-Laf-054070	Loxodonta africana	92.52	0.00e+00	907.00
IUUC-Meu-055917	Macropus eugenii	89.91	0.00e+00	953.00
IUUC-Mga-059273	Meleagris gallopavo	90.09	0.00e+00	885.00
IUUC-Mmr-061597	Microcebus murinus	96.64	0.00e+00	985.00
IUUC-Mdo-062492	Monodelphis domestica	65.01	2.00e-111	395.00
IUUC-Mmu-063374	Mus musculus	83.83	0.00e+00	841.00
IUUC-Mpu-065967	Mustela putorius furo	89.35	0.00e+00	897.00
IUUC-Mlu-067532	Myotis lucifugus	93.27	0.00e+00	936.00
IUUC-Nle-069373	Nomascus leucogenys	98.69	0.00e+00	1007.00
IUUC-Opr-070873	Ochotona princeps	90.84	0.00e+00	959.00
IUUC-Ont-072498	Oreochromis niloticus	71.40	0.00e+00	733.00
IUUC-Oan-072943	Ornithorhynchus anatinus	75.20	4.00e-97	347.00
IUUC-Ocu-073870	Oryctolagus cuniculus	94.58	0.00e+00	970.00
IUUC-Ola-086866	Oryzias latipes	89.40	4.00e-105	373.00
IUUC-Oga-089057	Otolemur garnettii	93.83	0.00e+00	934.00
IUUC-Oar-089841	Ovis aries	61.38	3.00e-167	581.00
IUUC-Ptr-091054	Pan troglodytes	98.69	0.00e+00	1006.00
IUUC-Pma-094253	Petromyzon marinus	44.14	1.00e-99	356.00
IUUC-Pfo-097179	Poecilia formosa	65.06	1.00e-176	612.00
IUUC-Pab-097702	Pongo abelii	98.69	0.00e+00	1006.00
IUUC-Pca-100671	Procavia capensis	86.64	2.00e-128	452.00
IUUC-Rno-106044	Rattus norvegicus	81.16	0.00e+00	829.00
IUUC-Sha-107139	Sarcophilus harrisii	89.16	0.00e+00	870.00
IUUC-Sly-111748	Solanum lycopersicum	46.15	2.70e-01	30.00
IUUC-Ssc-115343	Sus scrofa	92.71	0.00e+00	954.00
IUUC-Tgu-117061	Taeniopygia guttata	90.28	0.00e+00	894.00
IUUC-Tni-119829	Tetraodon nigroviridis	67.84	0.00e+00	650.00
IUUC-Ttr-129148	Tursiops truncatus	91.78	0.00e+00	895.00
IUUC-Vpa-130780	Vicugna pacos	90.09	0.00e+00	862.00
IUUC-Xtr-132513	Xenopus tropicalis	82.24	0.00e+00	849.00
IUUC-Xma-133904	Xiphophorus maculatus	69.13	0.00e+00	671.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence