iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ppe-101760

Ensembl Protein ID

EMJ06805

UniProt Accession

M5WJ19; M5WJ19_PRUPE

Genbank Protein ID

EMJ06805.1

Protein Name

E3 ubiquitin-protein ligase

Genbank Nucleotide ID

KB639090

Gene Name

PRUPE_ppa009039mg

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PRUPE_ppa009039mg	EMJ06805	EMJ06805

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	35.25	5.00e-40	161.00	IUUC-Dme-031700
E3 activity/RING/RING	36.10	2.00e-42	170.00	IUUC-Hsa-046357
E3 activity/RING/RING	36.10	1.00e-42	171.00	IUUC-Mmu-064129

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Prunus persica

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein Sequence
(Fasta)

MSPGGRFCED VAESRMAFAD SDVATSTGDV RTSPFRKAAP GLLGIPGMPS NHNVHDLLEC 60
PVCMNLMCPP IHQCPNGHTL CSSCKVRVHN CCPTCRNELG NIRCLALEKV AESLDLPCRY 120

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Nucleotide Sequence
(Fasta)

CGGCATTGAC ATTTGAGGAA GAAACATGTC TCCTGGAGGT CGCTTCTGTG AGGATGTGGC 60
TGAGTCTCGT ATGGCATTTG CAGATTCTGA TGTTGCAACT TCCACTGGTG ATGTAAGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR001370--BIR_rpt
IPR004162--SINA-like
IPR008974--TRAF-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS50089--ZF_RING_2
PS51081--ZF_SIAH

Pfam

PF03145--Sina

Gene Ontology

GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

pper:PRUPE_ppa009039mg

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001186	Ailuropoda melanoleuca	36.10	2.00e-44	171.00
IUUC-Apl-003813	Anas platyrhynchos	36.10	2.00e-44	171.00
IUUC-Aca-005014	Anolis carolinensis	36.10	3.00e-44	171.00
IUUC-Aly-006207	Arabidopsis lyrata	73.79	1.00e-138	484.00
IUUC-Ath-007049	Arabidopsis thaliana	73.62	4.00e-139	486.00
IUUC-Ame-011196	Astyanax mexicanus	36.10	5.00e-44	170.00
IUUC-Bta-012887	Bos taurus	36.10	3.00e-44	171.00
IUUC-Bol-016263	Brassica oleracea	73.62	7.00e-140	488.00
IUUC-Bra-016847	Brassica rapa	70.03	1.00e-131	461.00
IUUC-Cel-018320	Caenorhabditis elegans	34.80	2.00e-37	148.00
IUUC-Cja-019796	Callithrix jacchus	36.10	4.00e-44	170.00
IUUC-Cfa-020642	Canis familiaris	36.10	1.00e-44	172.00
IUUC-Cpo-022348	Cavia porcellus	36.10	5.00e-44	170.00
IUUC-Csa-023974	Chlorocebus sabaeus	36.10	4.00e-44	170.00
IUUC-Cho-024933	Choloepus hoffmanni	36.84	5.00e-39	153.00
IUUC-Cin-025674	Ciona intestinalis	33.56	1.00e-42	165.00
IUUC-Csv-026233	Ciona savignyi	35.57	3.00e-42	164.00
IUUC-Dre-028041	Danio rerio	36.10	1.00e-43	169.00
IUUC-Dno-029764	Dasypus novemcinctus	36.10	2.00e-44	171.00
IUUC-Dme-031700	Drosophila melanogaster	37.70	3.00e-37	147.00
IUUC-Ete-032423	Echinops telfairi	35.79	8.00e-44	169.00
IUUC-Eca-033536	Equus caballus	36.10	2.00e-44	171.00
IUUC-Eeu-035314	Erinaceus europaeus	35.79	6.00e-44	170.00
IUUC-Fca-035362	Felis catus	36.10	2.00e-44	171.00
IUUC-Fal-037487	Ficedula albicollis	35.71	1.00e-45	175.00
IUUC-Gmo-039091	Gadus morhua	35.97	7.00e-37	146.00
IUUC-Gga-040269	Gallus gallus	36.10	2.00e-44	171.00
IUUC-Gac-042282	Gasterosteus aculeatus	36.10	1.00e-43	169.00
IUUC-Ggo-045444	Gorilla gorilla	36.10	4.00e-44	170.00
IUUC-Hsa-046357	Homo sapiens	36.10	4.00e-44	170.00
IUUC-Itr-048046	Ictidomys tridecemlineatus	36.10	5.00e-44	170.00
IUUC-Lch-049504	Latimeria chalumnae	36.67	4.00e-44	170.00
IUUC-Loc-052191	Lepisosteus oculatus	36.10	2.00e-44	171.00
IUUC-Laf-053668	Loxodonta africana	36.10	2.00e-44	171.00
IUUC-Mcc-054640	Macaca mulatta	36.10	4.00e-44	170.00
IUUC-Meu-055922	Macropus eugenii	36.44	5.00e-38	150.00
IUUC-Mtr-057852	Medicago truncatula	68.61	8.00e-131	458.00
IUUC-Mga-059503	Meleagris gallopavo	35.47	2.00e-44	171.00
IUUC-Mmr-060794	Microcebus murinus	36.10	5.00e-44	170.00
IUUC-Mdo-061971	Monodelphis domestica	36.44	2.00e-38	152.00
IUUC-Mmu-064129	Mus musculus	36.10	3.00e-44	171.00
IUUC-Mpu-066488	Mustela putorius furo	36.10	2.00e-44	171.00
IUUC-Mlu-067207	Myotis lucifugus	36.10	2.00e-44	171.00
IUUC-Nle-069706	Nomascus leucogenys	36.10	4.00e-44	170.00
IUUC-Ont-071849	Oreochromis niloticus	36.10	1.00e-43	169.00
IUUC-Ocu-074876	Oryctolagus cuniculus	35.71	3.00e-44	171.00
IUUC-Ola-086814	Oryzias latipes	36.10	1.00e-43	169.00
IUUC-Oga-088114	Otolemur garnettii	35.42	3.00e-44	171.00
IUUC-Oar-089323	Ovis aries	36.10	3.00e-44	171.00
IUUC-Ptr-090692	Pan troglodytes	36.10	6.00e-44	170.00
IUUC-Pan-092012	Papio anubis	36.10	4.00e-44	170.00
IUUC-Psi-093687	Pelodiscus sinensis	35.37	2.00e-44	171.00
IUUC-Pma-094387	Petromyzon marinus	35.97	9.00e-45	172.00
IUUC-Pfo-097134	Poecilia formosa	36.10	1.00e-43	169.00
IUUC-Pab-097555	Pongo abelii	36.10	4.00e-44	170.00
IUUC-Pop-099563	Populus trichocarpa	73.63	1.00e-140	491.00
IUUC-Pca-100328	Procavia capensis	36.03	2.00e-36	145.00
IUUC-Rno-104866	Rattus norvegicus	36.10	3.00e-44	171.00
IUUC-Sha-106547	Sarcophilus harrisii	36.10	2.00e-44	171.00
IUUC-Sly-111117	Solanum lycopersicum	72.96	5.00e-140	489.00
IUUC-Stu-112714	Solanum tuberosum	72.17	8.00e-138	481.00
IUUC-Ssc-116441	Sus scrofa	36.84	5.00e-39	153.00
IUUC-Tgu-116579	Taeniopygia guttata	36.10	2.00e-44	171.00
IUUC-Tru-118250	Takifugu rubripes	35.53	2.00e-41	161.00
IUUC-Tni-120488	Tetraodon nigroviridis	35.87	1.00e-41	162.00
IUUC-Ttr-129166	Tursiops truncatus	36.93	1.00e-40	159.00
IUUC-Vpa-130799	Vicugna pacos	33.74	5.00e-18	82.80
IUUC-Vvi-131451	Vitis vinifera	79.55	2.00e-153	533.00
IUUC-Xtr-132553	Xenopus tropicalis	36.10	4.00e-44	170.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence