iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093293

Ensembl Protein ID

ENSPSIP00000004118.1

UniProt Accession

K7F7V8; K7F7V8_PELSI

Genbank Protein ID

ENSPSIP00000004118

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01070258

Gene Name

TRIM8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000003881.1	ENSPSIT00000004141.1	ENSPSIP00000004118.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	4.50e-06	26.7	11	80
E3 activity/RING/RING	6.70e-08	33.0	15	56

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssI.ekwlasggk.tcPvtrqpl.teedlvPnltlrrliqawce 70
           ee++CpI l ++ +Pv lp+ + + r +I e w ++ g   cP ++q   ++ +l  nl l ++++++ +
   Q: 11   EELICPICLHVFVEPVQLPCKHNFCRGCIgEAWAKEAGLvRCPECNQAYnQKPNLEKNLKLTNIVEKFNS 80
           799**************************677887777689********666677999999999998865 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCl  f + p+ lpC+H f++ C+ ++w     ++ +  rCP C+
   Q: 15   CPICLHVFVE-PVQLPCKHNFCRGCIgEAW----AKEAGLVRCPECN 56
           ********99.999****************....88**********7 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MAENWKNCFE EELICPICLH VFVEPVQLPC KHNFCRGCIG EAWAKEAGLV RCPECNQAYN 60
QKPNLEKNLK LTNIVEKFNS LNLEKTPSVL HCVFCRRGPP LPAQKICLRC EAPCCQSHVQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGGTTTTTA TGGAACTTGG ACTCTGCTAC TGGATTTTGT ATGGATTTTT TCCCCCCCGT 60
CTTTGGTAAG TTTTGATTCA CCTTCCGGAA TCAAAAGAAA CAAAACTGTA TATAAGAGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005829--C:cytosol
GO:0016605--C:PML body
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0046597--P:negative regulation of viral entry into host cell
GO:1902187--P:negative regulation of viral release from host cell
GO:0032897--P:negative regulation of viral transcription
GO:0010508--P:positive regulation of autophagy
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:1900182--P:positive regulation of protein localization to nucleus
GO:0019827--P:stem cell population maintenance

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001258	Ailuropoda melanoleuca	84.35	0.00e+00	994.00
IUUC-Apl-004223	Anas platyrhynchos	95.14	0.00e+00	1068.00
IUUC-Aca-005106	Anolis carolinensis	94.77	0.00e+00	1102.00
IUUC-Ame-011348	Astyanax mexicanus	67.36	0.00e+00	766.00
IUUC-Bta-012787	Bos taurus	84.50	0.00e+00	1001.00
IUUC-Cja-019471	Callithrix jacchus	83.96	0.00e+00	994.00
IUUC-Cfa-020052	Canis familiaris	84.50	0.00e+00	999.00
IUUC-Cpo-022491	Cavia porcellus	79.56	2.00e-177	614.00
IUUC-Cre-022597	Chlamydomonas reinhardtii	32.88	7.00e-08	51.60
IUUC-Csa-023544	Chlorocebus sabaeus	84.32	0.00e+00	998.00
IUUC-Dre-028013	Danio rerio	66.61	0.00e+00	763.00
IUUC-Dno-029676	Dasypus novemcinctus	84.32	0.00e+00	1000.00
IUUC-Dor-030402	Dipodomys ordii	83.78	0.00e+00	992.00
IUUC-Ete-033188	Echinops telfairi	76.12	0.00e+00	889.00
IUUC-Eca-033524	Equus caballus	83.99	0.00e+00	988.00
IUUC-Eeu-034979	Erinaceus europaeus	78.40	7.00e-117	414.00
IUUC-Fca-036362	Felis catus	84.50	0.00e+00	996.00
IUUC-Fal-036652	Ficedula albicollis	93.96	0.00e+00	1053.00
IUUC-Gmo-039405	Gadus morhua	59.08	2.00e-180	625.00
IUUC-Gga-040813	Gallus gallus	95.50	0.00e+00	1073.00
IUUC-Gac-041792	Gasterosteus aculeatus	61.40	0.00e+00	637.00
IUUC-Ggo-044962	Gorilla gorilla	83.96	0.00e+00	994.00
IUUC-Hsa-046158	Homo sapiens	83.78	0.00e+00	991.00
IUUC-Itr-048118	Ictidomys tridecemlineatus	84.14	0.00e+00	996.00
IUUC-Lch-049433	Latimeria chalumnae	83.16	0.00e+00	908.00
IUUC-Loc-052026	Lepisosteus oculatus	76.83	0.00e+00	885.00
IUUC-Laf-054159	Loxodonta africana	80.73	0.00e+00	787.00
IUUC-Mcc-055490	Macaca mulatta	84.32	0.00e+00	998.00
IUUC-Meu-056549	Macropus eugenii	83.54	0.00e+00	695.00
IUUC-Mga-059334	Meleagris gallopavo	95.50	0.00e+00	1068.00
IUUC-Mmr-061672	Microcebus murinus	84.68	0.00e+00	1002.00
IUUC-Mdo-061849	Monodelphis domestica	84.63	0.00e+00	884.00
IUUC-Mmu-063537	Mus musculus	83.96	0.00e+00	993.00
IUUC-Mpu-065762	Mustela putorius furo	84.68	0.00e+00	1002.00
IUUC-Mlu-066979	Myotis lucifugus	80.82	0.00e+00	664.00
IUUC-Nle-069419	Nomascus leucogenys	83.96	0.00e+00	994.00
IUUC-Opr-070981	Ochotona princeps	84.50	0.00e+00	1003.00
IUUC-Ont-072053	Oreochromis niloticus	57.80	7.00e-173	600.00
IUUC-Oan-073608	Ornithorhynchus anatinus	91.90	0.00e+00	873.00
IUUC-Ocu-074694	Oryctolagus cuniculus	85.23	0.00e+00	977.00
IUUC-Ola-086949	Oryzias latipes	59.38	3.00e-171	594.00
IUUC-Oga-089175	Otolemur garnettii	84.14	0.00e+00	998.00
IUUC-Oar-089591	Ovis aries	75.24	0.00e+00	780.00
IUUC-Ptr-091309	Pan troglodytes	82.88	0.00e+00	959.00
IUUC-Pan-091903	Papio anubis	84.32	0.00e+00	998.00
IUUC-Pfo-097191	Poecilia formosa	64.30	7.00e-140	490.00
IUUC-Pab-098251	Pongo abelii	80.54	0.00e+00	944.00
IUUC-Pca-100504	Procavia capensis	84.14	0.00e+00	997.00
IUUC-Pva-102320	Pteropus vampyrus	83.96	0.00e+00	962.00
IUUC-Rno-105545	Rattus norvegicus	83.96	0.00e+00	993.00
IUUC-Ssc-116121	Sus scrofa	84.50	0.00e+00	1001.00
IUUC-Tgu-116724	Taeniopygia guttata	94.95	0.00e+00	1064.00
IUUC-Tru-118048	Takifugu rubripes	58.33	9.00e-177	613.00
IUUC-Tni-120856	Tetraodon nigroviridis	58.66	6.00e-168	583.00
IUUC-Tbe-127400	Tupaia belangeri	68.41	1.00e-137	482.00
IUUC-Ttr-128233	Tursiops truncatus	83.60	0.00e+00	976.00
IUUC-Xtr-132578	Xenopus tropicalis	90.27	0.00e+00	1028.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence