iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tae-125292

Ensembl Protein ID

TRIAE_CS42_7AS_TGACv1_571321_AA1846800.2

UniProt Accession

A0A1D6C0G5; A0A1D6C0G5_WHEAT

Protein Name

Coatomer subunit beta'

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TRIAE_CS42_7AS_TGACv1_571321_AA1846800	TRIAE_CS42_7AS_TGACv1_571321_AA1846800.1	TRIAE_CS42_7AS_TGACv1_571321_AA1846800.1
TRIAE_CS42_7AS_TGACv1_571321_AA1846800	TRIAE_CS42_7AS_TGACv1_571321_AA1846800.2	TRIAE_CS42_7AS_TGACv1_571321_AA1846800.2
TRIAE_CS42_7AS_TGACv1_571321_AA1846800	TRIAE_CS42_7AS_TGACv1_571321_AA1846800.3	TRIAE_CS42_7AS_TGACv1_571321_AA1846800.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-33	115.8	183	224
UBD/Beta-Prp	1.70e-66	227.1	10	296

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+ +v+c+++    d ++l++GsdD t kvWD+ t  ++++
   Q: 183  GHQKGVNCVDYftgGDrPYLITGSDDSTAKVWDYQTKSCVQT 224
           8********966*9778*******************999986 PP

UBD/Beta-Prp

   S: 5    lkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseD 73
            ++++++++++v+ +p +++++++ ++gt+ +wd++t+++++s++  e +v++ kf +++++ v g++D
   Q: 10   KFAQRSERVKSVDLHPTEPWILASLYSGTLCIWDYQTQTMVKSFEVSELPVRSAKFVSRKQWVVAGADD 78
           567788999************************************************************ PP
   S: 74   rtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvnc 142
           ++i+v++++t + + ++++h+d++++++++p+  +++s s+d  i++wd+++g+   ++++gh++ v+ 
   Q: 79   MFIRVYNYNTMDKIKVFEAHTDYIRCVAVHPTLPYMLSSSDDMLIKLWDWDKGWMCTQIFEGHSHYVMQ 147
           ******************************************************9999*********** PP
   S: 143  vvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvysls..fdsngkelvsgsldgtvklwd 208
           v+++p++ n ++s+slDrt ++W+l + +   tl g h++ v++++     ++++l++gs+d+t k+wd
   Q: 148  VTFNPKDtNTFASASLDRTTKIWSLGSPDPNFTLDG-HQKGVNCVDyfTGGDRPYLITGSDDSTAKVWD 215
           ***********************************9.*********7445566**************** PP
   S: 209  lqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgd 277
           +qt++cv+tl+ght n++ v f+p+  ++++gs+Dg++riW +++  l +tl++  ++v++v +++   
   Q: 216  YQTKSCVQTLEGHTHNISAVCFHPELPIIITGSEDGTVRIWHSTTYRLENTLNYGLERVWAVGYMKG-S 283
           **************************************************************99444.4 PP
   S: 278  nvlvlgsedskvn 290
           + +v g ++++++
   Q: 284  RRMVIGYDEGTIM 296
           5555555556655 PP

Organism

Triticum aestivum

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MPLRLEIKRK FAQRSERVKS VDLHPTEPWI LASLYSGTLC IWDYQTQTMV KSFEVSELPV 60
RSAKFVSRKQ WVVAGADDMF IRVYNYNTMD KIKVFEAHTD YIRCVAVHPT LPYMLSSSDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAAAATAAA AAAAATACGC ACAAAACCCC CTCCTCCCTC GCCTCCCCAT CTCTCCTACC 60
ACCCCGCTTC GCTCCTCCAC CGAGCTCGCG CGATCCGGCT CGCCCCCTCG CCGCCTCGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030663--C:COPI-coated vesicle membrane
GO:0000139--C:Golgi membrane
GO:0030117--C:membrane coat
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003976	Anas platyrhynchos	59.09	0.00e+00	1102.00
IUUC-Aca-004301	Anolis carolinensis	61.50	0.00e+00	1108.00
IUUC-Aly-006508	Arabidopsis lyrata	81.01	0.00e+00	1548.00
IUUC-Ath-007635	Arabidopsis thaliana	80.54	0.00e+00	1540.00
IUUC-Ani-009135	Aspergillus nidulans	54.66	0.00e+00	885.00
IUUC-Ate-010355	Aspergillus terreus	52.68	0.00e+00	877.00
IUUC-Ame-010922	Astyanax mexicanus	52.91	0.00e+00	947.00
IUUC-Bgr-012249	Blumeria graminis	52.64	0.00e+00	880.00
IUUC-Bta-013579	Bos taurus	61.40	0.00e+00	961.00
IUUC-Bdi-014102	Brachypodium distachyon	95.13	0.00e+00	1684.00
IUUC-Bol-016271	Brassica oleracea	80.11	0.00e+00	1529.00
IUUC-Bra-016617	Brassica rapa	84.22	0.00e+00	1472.00
IUUC-Cpo-022201	Cavia porcellus	61.33	0.00e+00	1100.00
IUUC-Csv-026012	Ciona savignyi	58.96	0.00e+00	968.00
IUUC-Cme-027219	Cyanidioschyzon merolae	48.17	0.00e+00	884.00
IUUC-Dre-027846	Danio rerio	62.02	0.00e+00	1101.00
IUUC-Dor-030462	Dipodomys ordii	58.92	0.00e+00	851.00
IUUC-Dse-031268	Dothistroma septosporum	51.64	0.00e+00	877.00
IUUC-Eca-034180	Equus caballus	59.81	0.00e+00	1057.00
IUUC-Eeu-035086	Erinaceus europaeus	50.22	9.00e-122	432.00
IUUC-Fca-036265	Felis catus	59.74	0.00e+00	1105.00
IUUC-Fal-037202	Ficedula albicollis	58.44	0.00e+00	1055.00
IUUC-Gma-044126	Glycine max	82.79	0.00e+00	1595.00
IUUC-Ggo-044984	Gorilla gorilla	61.26	0.00e+00	1099.00
IUUC-Hsa-046698	Homo sapiens	61.38	0.00e+00	1100.00
IUUC-Lch-050473	Latimeria chalumnae	58.79	0.00e+00	1110.00
IUUC-Loc-052675	Lepisosteus oculatus	61.19	0.00e+00	1100.00
IUUC-Meu-056174	Macropus eugenii	51.33	3.00e-106	380.00
IUUC-Mga-059875	Meleagris gallopavo	58.32	0.00e+00	1104.00
IUUC-Mac-064636	Musa acuminata	83.42	0.00e+00	1570.00
IUUC-Mpu-065961	Mustela putorius furo	61.38	0.00e+00	1101.00
IUUC-Mlu-067059	Myotis lucifugus	58.93	0.00e+00	1088.00
IUUC-Ncr-068659	Neurospora crassa	52.45	0.00e+00	885.00
IUUC-Nle-069034	Nomascus leucogenys	61.26	0.00e+00	1100.00
IUUC-Ont-071563	Oreochromis niloticus	61.90	0.00e+00	1095.00
IUUC-Oan-073416	Ornithorhynchus anatinus	61.87	0.00e+00	1044.00
IUUC-Oba-075760	Oryza barthii	90.76	0.00e+00	1679.00
IUUC-Ogu-078994	Oryza glumaepatula	90.76	0.00e+00	1677.00
IUUC-Oin-079211	Oryza indica	90.47	0.00e+00	1633.00
IUUC-Olo-080731	Oryza longistaminata	89.50	0.00e+00	1656.00
IUUC-Ome-081762	Oryza meridionalis	85.25	0.00e+00	1540.00
IUUC-Opu-083433	Oryza punctata	92.73	0.00e+00	1595.00
IUUC-Oga-088163	Otolemur garnettii	59.37	0.00e+00	1048.00
IUUC-Pma-094695	Petromyzon marinus	57.53	0.00e+00	968.00
IUUC-Pfo-096587	Poecilia formosa	61.53	0.00e+00	1093.00
IUUC-Pop-099634	Populus trichocarpa	82.82	0.00e+00	1551.00
IUUC-Pca-100965	Procavia capensis	60.48	0.00e+00	1065.00
IUUC-Pva-102451	Pteropus vampyrus	57.87	0.00e+00	846.00
IUUC-Rno-105979	Rattus norvegicus	53.58	0.00e+00	815.00
IUUC-Spo-108299	Schizosaccharomyces pombe	45.95	0.00e+00	796.00
IUUC-Sit-110239	Setaria italica	92.97	0.00e+00	1752.00
IUUC-Sar-113472	Sorex araneus	56.61	0.00e+00	761.00
IUUC-Ssc-115593	Sus scrofa	59.03	0.00e+00	1101.00
IUUC-Tgu-117239	Taeniopygia guttata	59.36	0.00e+00	1107.00
IUUC-Tru-118025	Takifugu rubripes	61.16	0.00e+00	1086.00
IUUC-Tca-121613	Theobroma cacao	84.95	0.00e+00	1622.00
IUUC-Tur-126283	Triticum urartu	89.92	0.00e+00	1623.00
IUUC-Tbe-127770	Tupaia belangeri	59.85	0.00e+00	884.00
IUUC-Vpa-130037	Vicugna pacos	50.54	5.00e-127	449.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence