iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-036461

Ensembl Protein ID

ENSFCAP00000008718.2

UniProt Accession

M3WBD2; M3WBD2_FELCA

Genbank Protein ID

ENSFCAP00000008718

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02181415

Gene Name

RNF14

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000009402.2	ENSFCAT00000009404.2	ENSFCAP00000008718.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	2.50e-55	188.1	220	433

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpekleeseikellveeelykryekllleevveadaalkw 90
           C++C++e+  +e++++leC+h++Ck+Clk+y+e++i++gqv++++cp+++cp+ +++ ++ke lve+el++ry++lll+++++ +a++ +
   Q: 220  CNICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQVKE-LVETELFARYDRLLLQSTLDLMADVVY 308
           **************************************************************.7************************** PP
   S: 91   cpapdCslvvllekeaekleve.cekcgkefCveCkeewHeglsCkelkeklakteeek........................eeaeske 155
           cp+p+C+l+v++e+     ++  c++c+++fC+ C+ ++H  + Ck ++ekl + ++e+                        ee+eske
   Q: 309  CPRPCCQLPVMQEPG---CTMGiCSSCNFAFCTLCRLTYHGVSPCKVTAEKLIDLRNEYlqadeankrfleqrygkrviqkalEEMESKE 395
           *************95...33337*********************************999******************************* PP
   S: 156  lleanskkCpkCkvyieknegCnhmtCakCkaefCwlC 193
           +le+nsk+Cp+C ++iek +gCn+mtC+ C+++fCw+C
   Q: 396  WLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWIC 433
           ************************************** PP

Organism

Felis catus

Protein Sequence
(Fasta)

MSSEDREAQE DELLALASIY DGDEFRKAES VQGGETRIYL DLPQNFKIFV SGNSNECLQN 60
SGFEYTICFL PPLVLNFELP PDYPSSSPPS FTLSGKWLSP TQLSALCKHL DNLWEEHRGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAAACTTAA ATTTACCAGG CGAGGCGGGG AGAGTGGTGA CGGCGATCGC CCCAGCACCG 60
CCGCCTTTGG CCTTCAGGGG GCGGCAGAGG GACCGGGCGG TCACGGCGGC TGCGCAAGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR006575--RWD-domain
IPR016135--UBQ-conjugating_enzyme/RWD
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50908--RWD
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01485--IBR
PF05773--RWD

SMART

SM00647--IBR
SM00591--RWD

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0060765--P:regulation of androgen receptor signaling pathway
GO:0007165--P:signal transduction

KEGG

fca:101081275

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001130	Aegilops tauschii	30.28	3.00e-51	196.00
IUUC-Aml-001458	Ailuropoda melanoleuca	97.90	0.00e+00	930.00
IUUC-Atr-002560	Amborella trichopoda	30.62	3.00e-44	173.00
IUUC-Apl-003680	Anas platyrhynchos	81.86	0.00e+00	776.00
IUUC-Aca-005000	Anolis carolinensis	72.28	0.00e+00	674.00
IUUC-Aly-006288	Arabidopsis lyrata	31.25	4.00e-54	206.00
IUUC-Ath-006719	Arabidopsis thaliana	31.17	1.00e-53	204.00
IUUC-Acl-008213	Aspergillus clavatus	25.27	1.00e-30	127.00
IUUC-Afl-008433	Aspergillus flavus	24.56	1.00e-30	128.00
IUUC-Afu-008772	Aspergillus fumigatus	25.27	3.00e-32	133.00
IUUC-Ani-009249	Aspergillus nidulans	25.00	3.00e-33	136.00
IUUC-Ang-009757	Aspergillus niger	28.85	6.00e-37	148.00
IUUC-Aor-009963	Aspergillus oryzae	24.56	3.00e-30	127.00
IUUC-Ate-010460	Aspergillus terreus	25.38	7.00e-32	132.00
IUUC-Ame-011312	Astyanax mexicanus	59.04	3.00e-146	511.00
IUUC-Bgr-012052	Blumeria graminis	23.76	2.00e-30	127.00
IUUC-Bta-013529	Bos taurus	97.68	0.00e+00	934.00
IUUC-Bci-013729	Botrytis cinerea	24.51	9.00e-27	115.00
IUUC-Bdi-014940	Brachypodium distachyon	31.82	1.00e-48	187.00
IUUC-Bra-016998	Brassica rapa	30.04	4.00e-50	192.00
IUUC-Cel-018547	Caenorhabditis elegans	31.17	2.00e-51	196.00
IUUC-Cja-019791	Callithrix jacchus	94.94	0.00e+00	911.00
IUUC-Cfa-020403	Canis familiaris	97.68	0.00e+00	934.00
IUUC-Cpo-022229	Cavia porcellus	91.81	0.00e+00	865.00
IUUC-Cre-022601	Chlamydomonas reinhardtii	33.95	4.00e-29	120.00
IUUC-Csa-024115	Chlorocebus sabaeus	96.20	0.00e+00	920.00
IUUC-Cho-024911	Choloepus hoffmanni	97.47	0.00e+00	931.00
IUUC-Cin-025578	Ciona intestinalis	42.13	2.00e-97	349.00
IUUC-Csv-026355	Ciona savignyi	41.05	8.00e-84	303.00
IUUC-Cgl-026439	Colletotrichum gloeosporioides	22.51	1.00e-24	107.00
IUUC-Cne-026782	Cryptococcus neoformans	25.07	1.00e-29	124.00
IUUC-Dre-027380	Danio rerio	57.51	1.00e-152	533.00
IUUC-Dno-029640	Dasypus novemcinctus	96.84	0.00e+00	920.00
IUUC-Dor-030681	Dipodomys ordii	96.62	0.00e+00	923.00
IUUC-Dse-031208	Dothistroma septosporum	24.13	3.00e-30	126.00
IUUC-Ete-033122	Echinops telfairi	60.92	8.00e-135	473.00
IUUC-Eca-033755	Equus caballus	95.72	0.00e+00	899.00
IUUC-Eeu-035034	Erinaceus europaeus	98.63	2.00e-73	269.00
IUUC-Fal-037516	Ficedula albicollis	80.84	0.00e+00	771.00
IUUC-Fso-038307	Fusarium solani	24.84	1.00e-24	107.00
IUUC-Gmo-039563	Gadus morhua	56.71	9.00e-149	519.00
IUUC-Ggr-039920	Gaeumannomyces graminis	24.92	8.00e-23	102.00
IUUC-Gga-040331	Gallus gallus	81.53	0.00e+00	761.00
IUUC-Gac-042164	Gasterosteus aculeatus	59.03	2.00e-158	551.00
IUUC-Gma-044080	Glycine max	32.00	1.00e-57	218.00
IUUC-Ggo-045257	Gorilla gorilla	95.78	0.00e+00	920.00
IUUC-Hsa-046887	Homo sapiens	96.52	0.00e+00	896.00
IUUC-Hvu-047317	Hordeum vulgare	29.55	7.00e-48	185.00
IUUC-Itr-048199	Ictidomys tridecemlineatus	97.26	0.00e+00	930.00
IUUC-Lch-050155	Latimeria chalumnae	63.73	7.00e-164	570.00
IUUC-Lpe-051669	Leersia perrieri	31.09	1.00e-38	154.00
IUUC-Loc-051779	Lepisosteus oculatus	60.05	2.00e-154	538.00
IUUC-Lma-052969	Leptosphaeria maculans	23.86	1.00e-29	124.00
IUUC-Laf-053488	Loxodonta africana	93.67	0.00e+00	894.00
IUUC-Mcc-054701	Macaca mulatta	96.96	0.00e+00	898.00
IUUC-Meu-056577	Macropus eugenii	82.55	8.00e-126	443.00
IUUC-Mor-057157	Magnaporthe oryzae	22.15	2.00e-27	117.00
IUUC-Mpo-057518	Magnaporthe poae	22.82	9.00e-27	115.00
IUUC-Mtr-058125	Medicago truncatula	30.18	4.00e-46	179.00
IUUC-Mga-059906	Meleagris gallopavo	81.74	0.00e+00	762.00
IUUC-Mvi-060374	Microbotryum violaceum	32.48	6.00e-34	138.00
IUUC-Mmr-061786	Microcebus murinus	98.73	0.00e+00	940.00
IUUC-Mdo-062453	Monodelphis domestica	90.57	0.00e+00	833.00
IUUC-Mmu-063521	Mus musculus	92.26	0.00e+00	828.00
IUUC-Mac-065119	Musa acuminata	29.93	7.00e-40	158.00
IUUC-Mpu-066274	Mustela putorius furo	97.89	0.00e+00	936.00
IUUC-Mlu-067202	Myotis lucifugus	92.61	0.00e+00	844.00
IUUC-Nfi-068564	Neosartorya fischeri	25.27	3.00e-31	130.00
IUUC-Ncr-068823	Neurospora crassa	23.67	4.00e-29	123.00
IUUC-Nle-068987	Nomascus leucogenys	96.75	0.00e+00	900.00
IUUC-Opr-070453	Ochotona princeps	93.67	0.00e+00	893.00
IUUC-Ont-072611	Oreochromis niloticus	57.56	8.00e-158	550.00
IUUC-Oan-073738	Ornithorhynchus anatinus	83.04	0.00e+00	754.00
IUUC-Ocu-074396	Oryctolagus cuniculus	96.20	0.00e+00	917.00
IUUC-Oba-075472	Oryza barthii	32.09	6.00e-44	172.00
IUUC-Obr-076277	Oryza brachyantha	31.15	2.00e-45	177.00
IUUC-Ogl-077046	Oryza glaberrima	31.78	2.00e-42	167.00
IUUC-Ogu-078634	Oryza glumaepatula	32.09	4.00e-44	172.00
IUUC-Oin-080080	Oryza indica	30.02	2.00e-44	173.00
IUUC-Olo-080828	Oryza longistaminata	29.45	8.00e-42	166.00
IUUC-Ome-081387	Oryza meridionalis	29.98	2.00e-47	183.00
IUUC-Oni-082934	Oryza nivara	32.09	4.00e-44	172.00
IUUC-Opu-083719	Oryza punctata	29.27	2.00e-41	163.00
IUUC-Oru-084518	Oryza rufipogon	32.09	4.00e-44	172.00
IUUC-Ola-087312	Oryzias latipes	58.26	1.00e-156	546.00
IUUC-Olu-087661	Ostreococcus lucimarinus	28.82	1.00e-46	181.00
IUUC-Oga-089129	Otolemur garnettii	97.89	0.00e+00	932.00
IUUC-Oar-089839	Ovis aries	97.47	0.00e+00	933.00
IUUC-Ptr-091626	Pan troglodytes	96.74	0.00e+00	898.00
IUUC-Pan-092798	Papio anubis	96.96	0.00e+00	898.00
IUUC-Psi-093253	Pelodiscus sinensis	80.97	0.00e+00	781.00
IUUC-Pma-094512	Petromyzon marinus	54.96	7.00e-144	503.00
IUUC-Pno-094937	Phaeosphaeria nodorum	23.46	5.00e-28	118.00
IUUC-Ppa-095211	Physcomitrella patens	30.07	2.00e-53	203.00
IUUC-Pfo-097049	Poecilia formosa	53.18	4.00e-138	484.00
IUUC-Pab-097911	Pongo abelii	96.52	0.00e+00	897.00
IUUC-Pop-099841	Populus trichocarpa	31.04	1.00e-49	191.00
IUUC-Pca-100814	Procavia capensis	75.05	0.00e+00	671.00
IUUC-Ppe-101972	Prunus persica	30.26	3.00e-49	189.00
IUUC-Pva-103038	Pteropus vampyrus	96.84	0.00e+00	922.00
IUUC-Pgr-103277	Puccinia graminis	32.70	5.00e-39	155.00
IUUC-Ptt-103855	Puccinia triticina	30.37	8.00e-35	141.00
IUUC-Pte-104113	Pyrenophora teres	23.90	1.00e-26	114.00
IUUC-Pyt-104619	Pyrenophora triticirepentis	23.24	2.00e-27	117.00
IUUC-Rno-106003	Rattus norvegicus	92.64	0.00e+00	845.00
IUUC-Sce-106287	Saccharomyces cerevisiae	27.91	5.00e-24	105.00
IUUC-Sha-106652	Sarcophilus harrisii	90.24	0.00e+00	842.00
IUUC-Spo-108167	Schizosaccharomyces pombe	29.81	3.00e-51	195.00
IUUC-Ssl-108396	Sclerotinia sclerotiorum	24.55	3.00e-09	57.00
IUUC-Smo-109393	Selaginella moellendorffii	31.04	9.00e-49	187.00
IUUC-Sit-110529	Setaria italica	33.76	4.00e-42	166.00
IUUC-Sly-111829	Solanum lycopersicum	30.82	8.00e-52	198.00
IUUC-Stu-112811	Solanum tuberosum	31.49	2.00e-52	200.00
IUUC-Sar-113259	Sorex araneus	91.01	6.00e-139	487.00
IUUC-Sbi-114591	Sorghum bicolor	31.88	2.00e-35	143.00
IUUC-Sre-115227	Sporisorium reilianum	27.42	1.00e-35	144.00
IUUC-Ssc-115293	Sus scrofa	95.78	0.00e+00	917.00
IUUC-Tgu-117335	Taeniopygia guttata	81.78	0.00e+00	770.00
IUUC-Tru-118458	Takifugu rubripes	57.20	7.00e-155	540.00
IUUC-Tsy-119475	Tarsius syrichta	89.03	0.00e+00	825.00
IUUC-Tni-119827	Tetraodon nigroviridis	56.90	2.00e-153	535.00
IUUC-Tca-121023	Theobroma cacao	32.02	8.00e-51	195.00
IUUC-Tre-121965	Trichoderma reesei	23.04	6.00e-30	125.00
IUUC-Tvi-122564	Trichoderma virens	22.20	4.00e-26	113.00
IUUC-Tae-124793	Triticum aestivum	33.19	5.00e-40	159.00
IUUC-Tur-126258	Triticum urartu	30.47	7.00e-45	175.00
IUUC-Tbe-127227	Tupaia belangeri	76.02	7.00e-81	294.00
IUUC-Ttr-128984	Tursiops truncatus	74.68	0.00e+00	644.00
IUUC-Uma-129565	Ustilago maydis	28.34	2.00e-33	137.00
IUUC-Vpa-130301	Vicugna pacos	98.52	0.00e+00	942.00
IUUC-Vvi-131244	Vitis vinifera	30.36	4.00e-52	199.00
IUUC-Xtr-132880	Xenopus tropicalis	59.96	2.00e-165	575.00
IUUC-Xma-134055	Xiphophorus maculatus	58.40	5.00e-158	550.00
IUUC-Yli-134342	Yarrowia lipolytica	29.53	3.00e-43	169.00
IUUC-Zma-135021	Zea mays	32.78	9.00e-38	151.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence