iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000006137.2	ENSPPYT00000033317.1	ENSPPYP00000024054.1
ENSPPYG00000006137.2	ENSPPYT00000007251.1	ENSPPYP00000006976.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.70e-18	64.0	352	385

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 5    svtclaf...sd.tllvs..GsdDgtikvWDlrt 32
            vtc+af   ++ t l++   s+D+++ vWD+ +
   Q: 352  AVTCIAFsksNGgTNLCAvdDSNDHVLSVWDWQK 385
           59*******7556555555899*********865 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MSDGEGPSAD DSASAASSME VTDRIASLEQ RVQMQEDDIQ LLKSALADVV RRLNITEEQQ 60
AVLNRKGPTK ARPLMQTLPL RTTVNNGTVL PKKPTGSLPS PSGVRKETAV PATKRLNRSV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAACCGTTC CCAAGGAAAG AGTGTACAGG CATTCCCAAG TCCCTGGGAG CTAGAGTCTT 60
GGGGACTGAC CAAGCACCTA GGGGTGCAGT GGCTTCTCAA GCAACCTCCT GGGGCTGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:1990023--C:mitotic spindle midzone
GO:0097431--C:mitotic spindle pole
GO:0007420--P:brain development
GO:0002244--P:hematopoietic progenitor cell differentiation
GO:0007052--P:mitotic spindle organization
GO:0007405--P:neuroblast proliferation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002077	Ailuropoda melanoleuca	92.39	0.00e+00	1482.00
IUUC-Apl-004179	Anas platyrhynchos	88.44	0.00e+00	1423.00
IUUC-Aca-004993	Anolis carolinensis	85.30	0.00e+00	1375.00
IUUC-Ame-011332	Astyanax mexicanus	74.70	0.00e+00	1269.00
IUUC-Bta-013419	Bos taurus	80.24	0.00e+00	1271.00
IUUC-Cel-018623	Caenorhabditis elegans	28.94	6.00e-82	298.00
IUUC-Cja-018976	Callithrix jacchus	96.59	0.00e+00	1556.00
IUUC-Cfa-021276	Canis familiaris	91.87	0.00e+00	1465.00
IUUC-Csa-023355	Chlorocebus sabaeus	96.90	0.00e+00	1568.00
IUUC-Cin-025784	Ciona intestinalis	55.69	0.00e+00	742.00
IUUC-Csv-026305	Ciona savignyi	46.84	0.00e+00	734.00
IUUC-Dre-028728	Danio rerio	75.67	0.00e+00	1279.00
IUUC-Dno-029055	Dasypus novemcinctus	92.71	0.00e+00	1511.00
IUUC-Dor-030628	Dipodomys ordii	92.70	0.00e+00	1470.00
IUUC-Dme-032093	Drosophila melanogaster	36.46	4.00e-121	429.00
IUUC-Ete-032845	Echinops telfairi	94.78	0.00e+00	812.00
IUUC-Eca-034266	Equus caballus	91.48	0.00e+00	1513.00
IUUC-Fca-035446	Felis catus	91.67	0.00e+00	1471.00
IUUC-Fal-036734	Ficedula albicollis	89.79	0.00e+00	1454.00
IUUC-Gmo-038689	Gadus morhua	71.07	0.00e+00	1224.00
IUUC-Gga-040934	Gallus gallus	89.89	0.00e+00	1115.00
IUUC-Gac-042476	Gasterosteus aculeatus	72.79	0.00e+00	1236.00
IUUC-Ggo-044828	Gorilla gorilla	97.32	0.00e+00	1598.00
IUUC-Hsa-045664	Homo sapiens	97.32	0.00e+00	1596.00
IUUC-Lch-050508	Latimeria chalumnae	82.58	0.00e+00	1386.00
IUUC-Loc-052823	Lepisosteus oculatus	80.45	0.00e+00	1362.00
IUUC-Laf-054164	Loxodonta africana	87.82	0.00e+00	1375.00
IUUC-Mcc-055810	Macaca mulatta	99.05	0.00e+00	1615.00
IUUC-Mga-059405	Meleagris gallopavo	85.70	0.00e+00	1402.00
IUUC-Mmr-061144	Microcebus murinus	94.04	0.00e+00	1506.00
IUUC-Mdo-062834	Monodelphis domestica	88.63	0.00e+00	1464.00
IUUC-Mmu-063955	Mus musculus	91.36	0.00e+00	1459.00
IUUC-Mpu-066240	Mustela putorius furo	91.36	0.00e+00	1442.00
IUUC-Mlu-067847	Myotis lucifugus	89.58	0.00e+00	1070.00
IUUC-Nle-069783	Nomascus leucogenys	94.89	0.00e+00	1536.00
IUUC-Opr-070409	Ochotona princeps	84.55	0.00e+00	1324.00
IUUC-Ont-072468	Oreochromis niloticus	75.00	0.00e+00	1273.00
IUUC-Oan-073315	Ornithorhynchus anatinus	90.63	0.00e+00	1461.00
IUUC-Ocu-074604	Oryctolagus cuniculus	91.84	0.00e+00	1249.00
IUUC-Ola-086734	Oryzias latipes	71.84	0.00e+00	1217.00
IUUC-Oga-089105	Otolemur garnettii	94.89	0.00e+00	1504.00
IUUC-Oar-090057	Ovis aries	91.47	0.00e+00	1492.00
IUUC-Ptr-091138	Pan troglodytes	97.32	0.00e+00	1597.00
IUUC-Pan-092691	Papio anubis	90.02	0.00e+00	1427.00
IUUC-Psi-093076	Pelodiscus sinensis	89.70	0.00e+00	1456.00
IUUC-Pma-094555	Petromyzon marinus	57.30	0.00e+00	825.00
IUUC-Pfo-096794	Poecilia formosa	73.40	0.00e+00	1230.00
IUUC-Pva-102676	Pteropus vampyrus	91.25	0.00e+00	1451.00
IUUC-Rno-105971	Rattus norvegicus	85.32	0.00e+00	1306.00
IUUC-Sha-107530	Sarcophilus harrisii	89.67	0.00e+00	1441.00
IUUC-Ssc-116169	Sus scrofa	78.68	0.00e+00	1019.00
IUUC-Tgu-117046	Taeniopygia guttata	88.21	0.00e+00	1414.00
IUUC-Tru-118596	Takifugu rubripes	70.63	0.00e+00	1216.00
IUUC-Tsy-119142	Tarsius syrichta	88.96	0.00e+00	1093.00
IUUC-Tni-120377	Tetraodon nigroviridis	72.33	0.00e+00	1228.00
IUUC-Tbe-127916	Tupaia belangeri	70.00	0.00e+00	1051.00
IUUC-Ttr-129042	Tursiops truncatus	93.68	0.00e+00	1543.00
IUUC-Xtr-132117	Xenopus tropicalis	80.17	0.00e+00	1319.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence