iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003626

Ensembl Protein ID

ENSAPLP00000004215.1

UniProt Accession

U3IAE4; U3IAE4_ANAPL

Genbank Protein ID

ENSAPLP00000004215

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01010430

Gene Name

AURKA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000004677.1	ENSAPLT00000004826.1	ENSAPLP00000004215.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	71.25	4.00e-153	538.00	IUUC-Hsa-046968

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

KAVYQLQIFS IVKKTANAVV DGPKRVPVSQ HSAQSRVLNS GGQAQRVLCP SNLAQRVPVQ 60
SQKSVPSNQK LSNNQTTQQP RPKFLVQPMA RPQVPSKTNE KPQQAPAPAK SSEAESSSKQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAGCTGTAT ATCAGTTGCA AATATTTTCT ATAGTAAAGG TCTGATGGCT TACAAGTTTT 60
TACTGCTATT CAGGCTTGTG TGGAAAAGTT CTATAGCCAG CTATAAATAA GCATGCTGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR030616--Aur
IPR030611--AURKA
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0043203--C:axon hillock
GO:0005829--C:cytosol
GO:0042585--C:germinal vesicle
GO:0072687--C:meiotic spindle
GO:0072686--C:mitotic spindle
GO:0048471--C:perinuclear region of cytoplasm
GO:0045120--C:pronucleus
GO:0005876--C:spindle microtubule
GO:0031616--C:spindle pole centrosome
GO:0005524--F:ATP binding
GO:0035174--F:histone serine kinase activity
GO:0009948--P:anterior/posterior axis specification
GO:0051642--P:centrosome localization
GO:0097421--P:liver regeneration
GO:0007100--P:mitotic centrosome separation
GO:0007052--P:mitotic spindle organization
GO:0043066--P:negative regulation of apoptotic process
GO:0032091--P:negative regulation of protein binding
GO:1990138--P:neuron projection extension
GO:1900195--P:positive regulation of oocyte maturation
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0071539--P:protein localization to centrosome
GO:0031647--P:regulation of protein stability
GO:0009611--P:response to wounding
GO:0007057--P:spindle assembly involved in female meiosis I

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000930	Aegilops tauschii	67.42	2.00e-106	377.00
IUUC-Aml-001426	Ailuropoda melanoleuca	73.78	5.00e-159	553.00
IUUC-Atr-002453	Amborella trichopoda	68.56	1.00e-108	385.00
IUUC-Aca-004602	Anolis carolinensis	70.28	9.00e-155	539.00
IUUC-Aly-005878	Arabidopsis lyrata	66.29	4.00e-105	374.00
IUUC-Ath-007117	Arabidopsis thaliana	66.29	8.00e-105	372.00
IUUC-Acl-008199	Aspergillus clavatus	57.46	8.00e-87	313.00
IUUC-Afl-008419	Aspergillus flavus	57.09	4.00e-86	311.00
IUUC-Afu-008751	Aspergillus fumigatus	57.46	2.00e-86	311.00
IUUC-Ani-009181	Aspergillus nidulans	57.09	1.00e-90	326.00
IUUC-Ang-009787	Aspergillus niger	57.09	7.00e-87	313.00
IUUC-Aor-009980	Aspergillus oryzae	57.09	4.00e-86	311.00
IUUC-Ate-010286	Aspergillus terreus	57.46	9.00e-87	313.00
IUUC-Ame-010849	Astyanax mexicanus	77.57	6.00e-133	466.00
IUUC-Bgr-012110	Blumeria graminis	60.07	1.00e-89	322.00
IUUC-Bta-013474	Bos taurus	75.13	2.00e-159	554.00
IUUC-Bci-013756	Botrytis cinerea	60.53	4.00e-95	341.00
IUUC-Bdi-014257	Brachypodium distachyon	68.56	6.00e-108	382.00
IUUC-Bol-016310	Brassica oleracea	67.68	5.00e-106	376.00
IUUC-Bra-017438	Brassica rapa	67.05	3.00e-106	377.00
IUUC-Cel-018157	Caenorhabditis elegans	63.04	1.00e-99	355.00
IUUC-Cja-019282	Callithrix jacchus	72.61	3.00e-157	547.00
IUUC-Cfa-020162	Canis familiaris	74.22	2.00e-159	554.00
IUUC-Cpo-021764	Cavia porcellus	68.43	2.00e-150	525.00
IUUC-Cre-022827	Chlamydomonas reinhardtii	69.32	2.00e-110	391.00
IUUC-Csa-023694	Chlorocebus sabaeus	71.83	8.00e-152	529.00
IUUC-Cho-024350	Choloepus hoffmanni	88.27	6.00e-102	362.00
IUUC-Cin-025542	Ciona intestinalis	73.46	1.00e-119	421.00
IUUC-Csv-025873	Ciona savignyi	73.56	1.00e-120	425.00
IUUC-Cgl-026632	Colletotrichum gloeosporioides	56.23	8.00e-83	300.00
IUUC-Cne-026928	Cryptococcus neoformans	62.26	3.00e-98	351.00
IUUC-Cme-027336	Cyanidioschyzon merolae	70.86	2.00e-121	428.00
IUUC-Dre-028198	Danio rerio	61.73	1.00e-136	479.00
IUUC-Dno-029928	Dasypus novemcinctus	72.92	1.00e-151	528.00
IUUC-Dor-030238	Dipodomys ordii	65.65	2.00e-138	484.00
IUUC-Dse-031266	Dothistroma septosporum	57.61	8.00e-93	333.00
IUUC-Dme-032007	Drosophila melanogaster	62.98	1.00e-103	369.00
IUUC-Ete-032911	Echinops telfairi	57.07	1.00e-106	379.00
IUUC-Eca-033749	Equus caballus	73.89	3.00e-158	550.00
IUUC-Eeu-035170	Erinaceus europaeus	71.29	2.00e-156	544.00
IUUC-Fca-035498	Felis catus	73.21	4.00e-160	556.00
IUUC-Fal-037397	Ficedula albicollis	94.27	1.00e-160	559.00
IUUC-Fox-037747	Fusarium oxysporum	59.70	3.00e-92	331.00
IUUC-Fso-038429	Fusarium solani	57.84	4.00e-88	317.00
IUUC-Gmo-039378	Gadus morhua	61.11	2.00e-133	468.00
IUUC-Ggr-039939	Gaeumannomyces graminis	59.70	2.00e-94	338.00
IUUC-Gga-040187	Gallus gallus	91.16	0.00e+00	662.00
IUUC-Gac-042223	Gasterosteus aculeatus	61.92	7.00e-140	489.00
IUUC-Gma-042870	Glycine max	63.93	3.00e-100	357.00
IUUC-Ggo-045617	Gorilla gorilla	72.77	2.00e-159	555.00
IUUC-Hsa-046968	Homo sapiens	72.77	3.00e-159	554.00
IUUC-Hvu-047072	Hordeum vulgare	56.49	3.00e-81	294.00
IUUC-Itr-048233	Ictidomys tridecemlineatus	62.44	1.00e-125	442.00
IUUC-Kpa-049093	Komagataella pastoris	57.85	1.00e-79	289.00
IUUC-Lch-050346	Latimeria chalumnae	66.92	3.00e-148	517.00
IUUC-Lpe-051466	Leersia perrieri	68.94	2.00e-108	384.00
IUUC-Lma-053006	Leptosphaeria maculans	59.16	1.00e-89	322.00
IUUC-Laf-053422	Loxodonta africana	71.78	1.00e-157	548.00
IUUC-Mcc-055245	Macaca mulatta	72.97	2.00e-151	528.00
IUUC-Mor-056952	Magnaporthe oryzae	58.21	1.00e-91	329.00
IUUC-Mpo-057605	Magnaporthe poae	60.07	9.00e-95	340.00
IUUC-Mtr-057726	Medicago truncatula	67.42	9.00e-107	379.00
IUUC-Mla-059174	Melampsora laricipopulina	65.25	1.00e-102	366.00
IUUC-Mga-059562	Meleagris gallopavo	74.37	2.00e-148	518.00
IUUC-Mvi-060305	Microbotryum violaceum	63.57	5.00e-95	341.00
IUUC-Mmr-061588	Microcebus murinus	73.26	2.00e-158	551.00
IUUC-Mdo-061914	Monodelphis domestica	74.03	8.00e-162	562.00
IUUC-Mmu-063288	Mus musculus	72.54	5.00e-152	530.00
IUUC-Mac-064969	Musa acuminata	67.80	2.00e-107	381.00
IUUC-Mpu-066855	Mustela putorius furo	73.52	5.00e-159	553.00
IUUC-Mlu-068046	Myotis lucifugus	73.01	8.00e-156	542.00
IUUC-Nfi-068527	Neosartorya fischeri	57.46	9.00e-87	313.00
IUUC-Ncr-068678	Neurospora crassa	60.22	2.00e-93	335.00
IUUC-Nle-069848	Nomascus leucogenys	72.98	3.00e-160	557.00
IUUC-Opr-070589	Ochotona princeps	70.98	1.00e-151	528.00
IUUC-Ont-071733	Oreochromis niloticus	60.71	3.00e-127	447.00
IUUC-Oan-073399	Ornithorhynchus anatinus	82.43	1.00e-151	528.00
IUUC-Ocu-074063	Oryctolagus cuniculus	73.15	1.00e-158	551.00
IUUC-Oba-075264	Oryza barthii	68.56	2.00e-107	381.00
IUUC-Obr-076048	Oryza brachyantha	68.18	3.00e-107	380.00
IUUC-Ogl-077637	Oryza glaberrima	68.56	2.00e-107	381.00
IUUC-Ogu-078830	Oryza glumaepatula	68.56	1.00e-107	381.00
IUUC-Oin-079150	Oryza indica	68.56	1.00e-107	382.00
IUUC-Olo-080398	Oryza longistaminata	53.36	1.00e-84	305.00
IUUC-Ome-081544	Oryza meridionalis	57.41	3.00e-91	327.00
IUUC-Oni-082250	Oryza nivara	68.56	1.00e-107	382.00
IUUC-Opu-083638	Oryza punctata	68.56	2.00e-107	381.00
IUUC-Oru-084981	Oryza rufipogon	68.56	1.00e-107	382.00
IUUC-Osa-085961	Oryza sativa	68.56	1.00e-107	382.00
IUUC-Olu-087880	Ostreococcus lucimarinus	69.40	9.00e-113	399.00
IUUC-Oga-088891	Otolemur garnettii	74.01	2.00e-157	548.00
IUUC-Oar-090021	Ovis aries	74.35	1.00e-155	542.00
IUUC-Ptr-091458	Pan troglodytes	73.03	2.00e-159	554.00
IUUC-Pan-092546	Papio anubis	72.35	2.00e-152	531.00
IUUC-Psi-093280	Pelodiscus sinensis	80.64	1.00e-174	605.00
IUUC-Pma-094298	Petromyzon marinus	78.49	1.00e-123	434.00
IUUC-Pno-094847	Phaeosphaeria nodorum	59.92	1.00e-88	319.00
IUUC-Ppa-095855	Physcomitrella patens	66.67	4.00e-109	387.00
IUUC-Pfo-096428	Poecilia formosa	63.93	1.00e-134	473.00
IUUC-Pab-098696	Pongo abelii	72.08	1.00e-157	548.00
IUUC-Pop-099405	Populus trichocarpa	67.05	9.00e-107	379.00
IUUC-Pca-100740	Procavia capensis	72.11	7.00e-156	543.00
IUUC-Ppe-101854	Prunus persica	67.42	2.00e-107	381.00
IUUC-Pva-103212	Pteropus vampyrus	73.63	4.00e-157	547.00
IUUC-Pgr-103474	Puccinia graminis	64.89	4.00e-101	361.00
IUUC-Ptt-103933	Puccinia triticina	49.81	4.00e-63	234.00
IUUC-Pte-104089	Pyrenophora teres	59.92	3.00e-90	325.00
IUUC-Pyt-104555	Pyrenophora triticirepentis	59.92	2.00e-90	325.00
IUUC-Rno-105057	Rattus norvegicus	73.08	9.00e-153	532.00
IUUC-Sha-107137	Sarcophilus harrisii	74.15	2.00e-161	561.00
IUUC-Sja-107767	Schizosaccharomyces japonicus	61.78	8.00e-100	356.00
IUUC-Spo-108078	Schizosaccharomyces pombe	62.69	2.00e-101	362.00
IUUC-Smo-109288	Selaginella moellendorffii	68.18	3.00e-110	390.00
IUUC-Sit-110246	Setaria italica	68.18	5.00e-107	380.00
IUUC-Sly-111379	Solanum lycopersicum	67.80	4.00e-107	380.00
IUUC-Stu-112777	Solanum tuberosum	66.67	1.00e-106	379.00
IUUC-Sbi-114325	Sorghum bicolor	67.80	4.00e-107	380.00
IUUC-Sre-115203	Sporisorium reilianum	60.90	4.00e-83	301.00
IUUC-Ssc-115361	Sus scrofa	73.37	2.00e-162	564.00
IUUC-Tgu-116967	Taeniopygia guttata	80.64	2.00e-170	591.00
IUUC-Tru-117570	Takifugu rubripes	64.18	2.00e-140	491.00
IUUC-Tsy-119280	Tarsius syrichta	81.52	4.00e-104	370.00
IUUC-Tni-120721	Tetraodon nigroviridis	62.34	2.00e-137	481.00
IUUC-Tca-121494	Theobroma cacao	63.80	1.00e-105	375.00
IUUC-Tre-121869	Trichoderma reesei	61.71	2.00e-94	338.00
IUUC-Tvi-122510	Trichoderma virens	60.97	1.00e-93	335.00
IUUC-Tae-123071	Triticum aestivum	67.42	2.00e-106	377.00
IUUC-Tur-126240	Triticum urartu	67.42	9.00e-106	375.00
IUUC-Tme-126921	Tuber melanosporum	61.34	6.00e-97	347.00
IUUC-Tbe-127872	Tupaia belangeri	67.96	2.00e-139	488.00
IUUC-Ttr-129134	Tursiops truncatus	74.61	5.00e-154	536.00
IUUC-Uma-129412	Ustilago maydis	60.75	2.00e-80	292.00
IUUC-Vda-130003	Verticillium dahliae	58.96	7.00e-93	333.00
IUUC-Vvi-131272	Vitis vinifera	67.05	2.00e-106	378.00
IUUC-Xtr-132019	Xenopus tropicalis	65.84	3.00e-149	521.00
IUUC-Xma-134203	Xiphophorus maculatus	62.25	8.00e-141	493.00
IUUC-Yli-134503	Yarrowia lipolytica	57.14	1.00e-90	325.00
IUUC-Zma-135232	Zea mays	67.42	9.00e-106	375.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence