iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-045634

Ensembl Protein ID

ENSGGOP00000021138.1

UniProt Accession

G3RZ95; G3RZ95_GORGO

Protein Name

Uncharacterized protein

Gene Name

DCAF6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000028357.1	ENSGGOT00000030131.1	ENSGGOP00000021138.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.80e-11	43.2	92	120

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf....sdtllvsGsdDgti 25
           gH + +++ +f    +d+ +vs+s+Dg+i
   Q: 92   GHRANIFSAKFlpctNDKQIVSCSGDGVI 120
           8************9777**********98 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MSRGGSCPHL LWDVRKRSLG LEDPSRLRSR YLGRREFIQR LKLEATLNVH DGCVNTICWN 60
DAGEYILSGP DDTKLVISNP YSRKVLTTIR SGHRANIFSA KFLPCTNDKQ IVSCSGDGVI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTCGGG GTGGCTCCTG CCCACACCTG TTGTGGGACG TGAGGAAAAG GTCCCTCGGG 60
CTGGAGGACC CGTCCCGGCT GCGGAGTCGC TACCTGGGTG AGCGGGGGCC CCGGGGCGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR000048--IQ_motif_EF-hand-BS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50096--IQ
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005925--C:focal adhesion
GO:0005634--C:nucleus
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001399	Ailuropoda melanoleuca	86.33	0.00e+00	649.00
IUUC-Apl-003181	Anas platyrhynchos	78.68	3.00e-155	542.00
IUUC-Aca-004953	Anolis carolinensis	74.39	5.00e-148	518.00
IUUC-Afu-008828	Aspergillus fumigatus	28.26	1.00e-23	105.00
IUUC-Ame-011314	Astyanax mexicanus	72.01	2.00e-149	523.00
IUUC-Bta-013552	Bos taurus	74.35	0.00e+00	1204.00
IUUC-Cja-019015	Callithrix jacchus	92.33	0.00e+00	675.00
IUUC-Cfa-021249	Canis familiaris	87.05	0.00e+00	656.00
IUUC-Cpo-021903	Cavia porcellus	81.90	2.00e-171	595.00
IUUC-Csa-023744	Chlorocebus sabaeus	95.80	0.00e+00	696.00
IUUC-Cho-024527	Choloepus hoffmanni	85.05	1.00e-160	560.00
IUUC-Dre-028040	Danio rerio	72.27	5.00e-148	518.00
IUUC-Dno-029777	Dasypus novemcinctus	84.96	0.00e+00	630.00
IUUC-Dor-030879	Dipodomys ordii	61.90	4.00e-154	538.00
IUUC-Ete-032607	Echinops telfairi	68.35	1.00e-139	490.00
IUUC-Eca-033396	Equus caballus	90.19	0.00e+00	662.00
IUUC-Eeu-034944	Erinaceus europaeus	70.50	2.00e-146	513.00
IUUC-Fca-036020	Felis catus	81.39	0.00e+00	666.00
IUUC-Fal-037527	Ficedula albicollis	64.47	0.00e+00	965.00
IUUC-Gmo-039347	Gadus morhua	70.21	1.00e-142	500.00
IUUC-Gga-040564	Gallus gallus	79.60	1.00e-165	577.00
IUUC-Gac-042029	Gasterosteus aculeatus	70.50	5.00e-143	501.00
IUUC-Hsa-045743	Homo sapiens	98.81	0.00e+00	713.00
IUUC-Itr-048064	Ictidomys tridecemlineatus	77.64	0.00e+00	1163.00
IUUC-Lch-050457	Latimeria chalumnae	73.85	2.00e-152	533.00
IUUC-Loc-052880	Lepisosteus oculatus	72.57	2.00e-147	516.00
IUUC-Lma-053032	Leptosphaeria maculans	30.65	1.00e-22	102.00
IUUC-Laf-053836	Loxodonta africana	81.90	7.00e-172	597.00
IUUC-Mcc-055749	Macaca mulatta	93.16	0.00e+00	694.00
IUUC-Mga-059293	Meleagris gallopavo	70.70	7.00e-141	494.00
IUUC-Mmr-060923	Microcebus murinus	90.41	0.00e+00	656.00
IUUC-Mdo-063056	Monodelphis domestica	81.90	5.00e-171	595.00
IUUC-Mmu-063121	Mus musculus	73.02	0.00e+00	1190.00
IUUC-Mpu-066035	Mustela putorius furo	86.50	5.00e-176	611.00
IUUC-Mlu-067903	Myotis lucifugus	84.29	2.00e-178	619.00
IUUC-Nfi-068606	Neosartorya fischeri	26.45	9.00e-23	102.00
IUUC-Nle-069415	Nomascus leucogenys	94.24	0.00e+00	657.00
IUUC-Opr-070809	Ochotona princeps	78.53	4.00e-141	495.00
IUUC-Ont-071470	Oreochromis niloticus	70.50	4.00e-143	501.00
IUUC-Oan-072748	Ornithorhynchus anatinus	70.15	7.00e-78	283.00
IUUC-Ocu-073865	Oryctolagus cuniculus	88.76	0.00e+00	641.00
IUUC-Ola-086755	Oryzias latipes	69.62	5.00e-142	498.00
IUUC-Oga-088309	Otolemur garnettii	89.93	0.00e+00	679.00
IUUC-Oar-090264	Ovis aries	85.37	0.00e+00	631.00
IUUC-Ptr-090603	Pan troglodytes	95.68	0.00e+00	673.00
IUUC-Pan-092480	Papio anubis	94.93	0.00e+00	731.00
IUUC-Psi-092973	Pelodiscus sinensis	75.89	8.00e-148	517.00
IUUC-Pfo-096506	Poecilia formosa	69.91	1.00e-141	496.00
IUUC-Pab-097581	Pongo abelii	88.86	0.00e+00	664.00
IUUC-Pca-100155	Procavia capensis	73.28	3.00e-148	519.00
IUUC-Pva-103022	Pteropus vampyrus	81.29	3.00e-173	602.00
IUUC-Pte-104187	Pyrenophora teres	31.06	2.00e-23	105.00
IUUC-Pyt-104546	Pyrenophora triticirepentis	30.68	6.00e-23	103.00
IUUC-Rno-105851	Rattus norvegicus	76.92	1.00e-173	603.00
IUUC-Sha-106790	Sarcophilus harrisii	70.07	0.00e+00	1078.00
IUUC-Sja-107779	Schizosaccharomyces japonicus	33.33	3.00e-27	117.00
IUUC-Spo-108129	Schizosaccharomyces pombe	35.61	5.00e-28	119.00
IUUC-Ssc-115801	Sus scrofa	82.55	4.00e-120	424.00
IUUC-Tgu-116760	Taeniopygia guttata	79.01	2.00e-153	536.00
IUUC-Tru-118422	Takifugu rubripes	69.91	3.00e-141	496.00
IUUC-Tni-120340	Tetraodon nigroviridis	69.91	3.00e-141	495.00
IUUC-Tbe-127997	Tupaia belangeri	79.35	5.00e-142	498.00
IUUC-Ttr-129311	Tursiops truncatus	86.09	5.00e-180	624.00
IUUC-Vpa-130145	Vicugna pacos	83.18	5.00e-174	605.00
IUUC-Xtr-132496	Xenopus tropicalis	55.73	0.00e+00	826.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence