iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-118577

Ensembl Protein ID

ENSTRUP00000018397.1

UniProt Accession

H2T159; H2T159_TAKRU

Protein Name

Uncharacterized protein

Gene Name

si:ch73-383g2.1; vav3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000007437.1	ENSTRUT00000018471.1	ENSTRUP00000018395.1
ENSTRUG00000007437.1	ENSTRUT00000018472.1	ENSTRUP00000018396.1
ENSTRUG00000007437.1	ENSTRUT00000018473.1	ENSTRUP00000018397.1
ENSTRUG00000007437.1	ENSTRUT00000018474.1	ENSTRUP00000018398.1
ENSTRUG00000007437.1	ENSTRUT00000018475.1	ENSTRUP00000018399.1
ENSTRUG00000007437.1	ENSTRUT00000018476.1	ENSTRUP00000018400.1
ENSTRUG00000007437.1	ENSTRUT00000018477.1	ENSTRUP00000018401.1
ENSTRUG00000007437.1	ENSTRUT00000018478.1	ENSTRUP00000018402.1
ENSTRUG00000007437.1	ENSTRUT00000018479.1	ENSTRUP00000018403.1
ENSTRUG00000007437.1	ENSTRUT00000018480.1	ENSTRUP00000018404.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.80e-17	64.3	768	819

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           ++ yd+++ ++ eL+l++Gdvv++   ++  +gW++g  e +g+ G fP+ +ve+
   Q: 768  IARYDFSSRDTRELSLQEGDVVKIY-TKSGANGWWRG--EVNGRVGWFPSTYVEE 819
           678*********************9.99*********..9*************97 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

TQFLCLKNIR TFLMACTEVF GMRKSELFES FDLFDVRDFG KVVDTLSKLS HTAIAQQTGI 60
RSFPSEESVE DEDIYNHLED LIDEKVVEDE EDLYDCVYDE EDGGEIYEDL MKTEALPPPG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACGCAGTTTC TGTGCCTGAA GAACATCCGG ACCTTCTTGA TGGCGTGCAC CGAGGTGTTT 60
GGCATGAGGA AAAGCGAGCT GTTTGAGTCC TTCGACCTTT TCGACGTCAG GGACTTTGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0862--Zinc

Interpro

IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR002219--PE/DAG-bd
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50001--SH2
PS50002--SH3
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2

Pfam

PF00130--C1_1
PF00307--CH
PF00621--RhoGEF
PF00017--SH2
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00109--C1
SM00233--PH
SM00325--RhoGEF
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0046872--F:metal ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003734	Anas platyrhynchos	66.39	0.00e+00	1063.00
IUUC-Aca-004477	Anolis carolinensis	67.43	0.00e+00	1063.00
IUUC-Cel-018578	Caenorhabditis elegans	26.94	7.00e-82	298.00
IUUC-Cfa-020266	Canis familiaris	65.23	0.00e+00	989.00
IUUC-Cpo-021966	Cavia porcellus	64.38	0.00e+00	966.00
IUUC-Csa-023892	Chlorocebus sabaeus	65.63	0.00e+00	1029.00
IUUC-Eca-033961	Equus caballus	65.72	0.00e+00	1014.00
IUUC-Eeu-034719	Erinaceus europaeus	50.93	4.00e-154	538.00
IUUC-Fal-036802	Ficedula albicollis	69.14	0.00e+00	1118.00
IUUC-Gmo-039409	Gadus morhua	73.98	0.00e+00	1180.00
IUUC-Gac-041395	Gasterosteus aculeatus	81.80	0.00e+00	1340.00
IUUC-Ggo-044460	Gorilla gorilla	63.73	0.00e+00	959.00
IUUC-Itr-048144	Ictidomys tridecemlineatus	67.38	0.00e+00	1033.00
IUUC-Lch-049650	Latimeria chalumnae	63.49	4.00e-92	330.00
IUUC-Loc-052487	Lepisosteus oculatus	71.89	0.00e+00	1157.00
IUUC-Nle-069863	Nomascus leucogenys	67.54	0.00e+00	1068.00
IUUC-Ont-072286	Oreochromis niloticus	80.65	0.00e+00	1311.00
IUUC-Ola-086336	Oryzias latipes	80.24	0.00e+00	1310.00
IUUC-Pan-092550	Papio anubis	67.81	0.00e+00	1049.00
IUUC-Psi-093784	Pelodiscus sinensis	67.87	0.00e+00	1062.00
IUUC-Pma-094372	Petromyzon marinus	51.15	0.00e+00	666.00
IUUC-Pfo-097308	Poecilia formosa	86.13	0.00e+00	1415.00
IUUC-Tsy-119429	Tarsius syrichta	60.98	0.00e+00	934.00
IUUC-Tni-119951	Tetraodon nigroviridis	83.31	0.00e+00	1313.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence