iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012545

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02062722

Gene Name

USP35

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000012944.5	ENSBTAT00000017198.5	ENSBTAP00000017198.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.10e-82	275.9	442	928

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtCY+NS+LQ+L++ +++r+++l+     l e+    ++++l+++lq lf+ l +s++ a+sp+++l+a +   + fs   qq
   Q: 442  GLINLGNTCYVNSILQALFMASDFRHCVLR-----LTEN----NSQPLMTKLQWLFAFLEHSQRPAISPENFLSASW--TPWFSPGTQQ 519
           9*****************************.....4433....3579***************************998..677******* PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           D++E+l++lld+l+ee      k+ ++ +++ k+++s + +e+++  + + ++++F+g++ ++i cl+c nvssree f+dlsl++p  
   Q: 520  DCSEYLKYLLDRLHEEE-----KTGTRICQKLKQSSSPSPPEEPPGPSATSVEKMFGGKIVTRICCLRCLNVSSREEAFTDLSLAFPPP 603
           *****************.....678888888888999999999********************************************88 PP
   S: 180  eetkke................................................................................... 185
           e +                                                                                      
   Q: 604  ERCRRHhhhhhhrrrrlgsvmlpaedagaqepgsagprrqrkhcitggvpptildmeglgphglggqsgqeekvergesteeeeaagee 692
           87766688999****************************************************************************** PP
   S: 186  .....................................................................slqdcLesftkeeelegenk 205
                                                                                s+ d+ + f ++e+l++en+
   Q: 693  eeeeeeekdkeeevkkkvkekveeeekveekekeaqeekeaaadgeeaaagpgpgtlqsaaaasgdgsrSVLDLVNYFLSPERLTSENR 781
           ***************************************************************************************** PP
   S: 206  yycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssG 293
           y+ce+c ++q+aek ++l++ P++Lil L Rfsf+ ++++r+ki + v++pl L l     +        + Y+L++vvvHsG s++sG
   Q: 782  YHCESCASLQDAEKVVELSQGPRYLILTLLRFSFDLRTMRRRKILDDVSVPLLLRLPLAGGR-------GQAYDLCSVVVHSGlSSESG 863
           ***************************************************99999855555.......89****************** PP
   S: 294  HYvayvkn................ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
           HY++y+++                 +++W+lf+D++V+ ++ e+v + t+    +taYvlfY++r
   Q: 864  HYYCYAREgaarpapalgaaerpePDNQWYLFNDTRVSFSSFESVSNVTSffpkDTAYVLFYRQR 928
           ********99999999999998888999*******************999************985 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MDKILEAVVT SSYPASVKQG LVRRVLEAAR QPLEREQCLA LLALGTRLYV SGADELPRRV 60
GCQLLHVAGR HHPEVFAEFF SARRVLRLLQ GGAGPPSARA LACVQLCLQL LPEGPGADEV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACAAGA TCCTGGAGGC CGTGGTGACA TCATCATACC CGGCGAGCGT GAAGCAAGGG 60
CTCGTGCGGC GCGTGCTGGA GGCGGCGCGG CAGCCGCTGG AGCGCGAGCA GTGCCTGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001744	Ailuropoda melanoleuca	81.03	0.00e+00	998.00
IUUC-Apl-004121	Anas platyrhynchos	67.21	0.00e+00	902.00
IUUC-Aca-005070	Anolis carolinensis	64.95	2.00e-169	589.00
IUUC-Cja-019731	Callithrix jacchus	91.64	0.00e+00	1168.00
IUUC-Cfa-020095	Canis familiaris	92.80	0.00e+00	1192.00
IUUC-Cpo-021961	Cavia porcellus	90.98	0.00e+00	1183.00
IUUC-Csa-023167	Chlorocebus sabaeus	91.53	0.00e+00	1163.00
IUUC-Dno-029186	Dasypus novemcinctus	82.79	0.00e+00	846.00
IUUC-Dor-030538	Dipodomys ordii	97.55	0.00e+00	1000.00
IUUC-Eca-033279	Equus caballus	96.74	0.00e+00	915.00
IUUC-Eeu-035120	Erinaceus europaeus	71.13	0.00e+00	855.00
IUUC-Fca-035969	Felis catus	91.96	0.00e+00	903.00
IUUC-Fal-037625	Ficedula albicollis	67.41	0.00e+00	904.00
IUUC-Gga-040767	Gallus gallus	67.16	0.00e+00	902.00
IUUC-Ggo-045323	Gorilla gorilla	91.37	0.00e+00	923.00
IUUC-Hsa-046124	Homo sapiens	92.17	0.00e+00	1156.00
IUUC-Itr-048704	Ictidomys tridecemlineatus	93.88	0.00e+00	1184.00
IUUC-Lch-049513	Latimeria chalumnae	57.82	0.00e+00	766.00
IUUC-Laf-053999	Loxodonta africana	89.17	0.00e+00	1155.00
IUUC-Mcc-055266	Macaca mulatta	90.62	0.00e+00	1138.00
IUUC-Meu-056906	Macropus eugenii	74.16	0.00e+00	997.00
IUUC-Mga-059595	Meleagris gallopavo	71.12	0.00e+00	884.00
IUUC-Mmr-061720	Microcebus murinus	90.34	0.00e+00	709.00
IUUC-Mdo-062167	Monodelphis domestica	73.65	0.00e+00	988.00
IUUC-Mmu-063298	Mus musculus	91.16	0.00e+00	1178.00
IUUC-Mpu-066195	Mustela putorius furo	92.65	0.00e+00	1181.00
IUUC-Mlu-067583	Myotis lucifugus	88.26	0.00e+00	801.00
IUUC-Opr-070454	Ochotona princeps	89.31	1.00e-162	566.00
IUUC-Ocu-074121	Oryctolagus cuniculus	85.81	0.00e+00	973.00
IUUC-Oga-088593	Otolemur garnettii	91.59	0.00e+00	1143.00
IUUC-Oar-090140	Ovis aries	99.24	0.00e+00	1232.00
IUUC-Pan-092168	Papio anubis	91.68	0.00e+00	1165.00
IUUC-Psi-093707	Pelodiscus sinensis	67.41	0.00e+00	906.00
IUUC-Pab-097614	Pongo abelii	91.62	0.00e+00	1152.00
IUUC-Pca-100683	Procavia capensis	86.18	0.00e+00	1134.00
IUUC-Pva-103146	Pteropus vampyrus	80.09	0.00e+00	1050.00
IUUC-Rno-105061	Rattus norvegicus	91.61	0.00e+00	1186.00
IUUC-Sha-106686	Sarcophilus harrisii	72.13	0.00e+00	970.00
IUUC-Tgu-117024	Taeniopygia guttata	72.53	0.00e+00	909.00
IUUC-Tsy-119505	Tarsius syrichta	78.10	9.00e-167	580.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence