iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074121

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02008314

Gene Name

USP35

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000021262.2	ENSOCUT00000027704.2	ENSOCUP00000021138.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	9.20e-77	258.5	438	837

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtCY+NS+LQ+L++ +++r+++l+     l e    +++++l+++lq lf+ l +s++ a+sp+++l+a +   + fs   qq
   Q: 438  GLINLGNTCYVNSILQALFMASDFRHCVLR-----LTE----DNSQPLMTKLQWLFAFLEHSQRPAISPENFLSASW--TPWFSPGTQQ 515
           9*****************************.....443....34689***************************998..677******* PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           D++E+l++lld+l+ee      k+ ++ +++ k+++   ++ +++    + ++++F+g++ ++i+cl+c nvssree  +dls+++   
   Q: 516  DCSEYLKYLLDRLHEEE-----KTGTRICQKLKQSSA-PSPPEEPPGPGTSVETMFGGKIVTRIRCLRCLNVSSREE-ATDLSVAFGPP 597
           *****************.....344444444433333.3455667777799**********************9887.69******998 PP
   S: 180  eetkke.......................................................................slqdcLesftke 197
           e +  +                                                                       s+ d+ + f ++
   Q: 598  ERCRRRrrlgsvlqpaeeassaspatprlpccsstawahragrsrvegprgeqqpppdlgprhqgaaaapsgpegsrSVLDLVNYFLSP 686
           88877789********************************************************************************* PP
   S: 198  eelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvH 286
           e+l+ en+y ce+c ++q+aek ++l++ P++Lil L Rfsf+ ++++r+ki + v +pl L l     +        + Y+L++vvvH
   Q: 687  ERLTAENRYRCESCASLQDAEKVVELSQGPRYLILTLLRFSFDLRTMRRRKILDDVAIPLLLRLPLAGGR-------GQAYDLCSVVVH 768
           ***********************************************************99999855555.......89********** PP
   S: 287  sG.slssGHYvayvkn............ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
           sG s++sGHY++y+++             +++W+lf+D++V+ ++ e+v + t+    +taYvlfY++r
   Q: 769  SGvSSESGHYYCYAREgaarpaaadrpePENQWYLFNDTRVSFSSFESVSNVTSffpkDTAYVLFYRQR 837
           ****************9999999988888999*******************999************985 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

PCNAAIMDKI LEAVVTSSYP ASVKQGLVRR VLEAARQPLE REQCLALLAL GARLYVGGTE 60
ELPRRVGCQL LHVAGRHHPD VFAEFFSARR VLRLLLACVQ LGLQLLPEGP AADEVFALLR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCTGCAACG CGGCCATCAT GGACAAGATC CTGGAGGCGG TGGTGACGTC GTCGTACCCC 60
GCGAGCGTGA AGCAGGGGCT CGTGCGGCGC GTGCTGGAGG CGGCGCGGCA GCCGCTGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001744	Ailuropoda melanoleuca	76.47	0.00e+00	845.00
IUUC-Apl-004121	Anas platyrhynchos	59.79	0.00e+00	997.00
IUUC-Aca-005070	Anolis carolinensis	57.64	0.00e+00	689.00
IUUC-Bta-012545	Bos taurus	84.04	0.00e+00	979.00
IUUC-Cja-019731	Callithrix jacchus	83.23	0.00e+00	976.00
IUUC-Cfa-020095	Canis familiaris	85.44	0.00e+00	996.00
IUUC-Cpo-021961	Cavia porcellus	80.27	0.00e+00	1118.00
IUUC-Csa-023167	Chlorocebus sabaeus	80.21	0.00e+00	1244.00
IUUC-Dno-029186	Dasypus novemcinctus	83.33	0.00e+00	775.00
IUUC-Dor-030538	Dipodomys ordii	87.80	0.00e+00	871.00
IUUC-Ete-032512	Echinops telfairi	91.97	2.00e-101	363.00
IUUC-Eca-033279	Equus caballus	84.11	0.00e+00	782.00
IUUC-Eeu-035120	Erinaceus europaeus	63.60	0.00e+00	658.00
IUUC-Fca-035969	Felis catus	80.79	0.00e+00	729.00
IUUC-Fal-037625	Ficedula albicollis	59.88	0.00e+00	1014.00
IUUC-Gga-040767	Gallus gallus	59.76	0.00e+00	1033.00
IUUC-Ggo-045323	Gorilla gorilla	84.60	0.00e+00	768.00
IUUC-Hsa-046124	Homo sapiens	85.30	0.00e+00	988.00
IUUC-Itr-048704	Ictidomys tridecemlineatus	82.21	0.00e+00	1344.00
IUUC-Lch-049513	Latimeria chalumnae	53.96	0.00e+00	862.00
IUUC-Laf-053999	Loxodonta africana	83.40	0.00e+00	1338.00
IUUC-Mcc-055266	Macaca mulatta	84.24	0.00e+00	964.00
IUUC-Meu-056906	Macropus eugenii	67.38	0.00e+00	838.00
IUUC-Mga-059595	Meleagris gallopavo	59.75	0.00e+00	1009.00
IUUC-Mdo-062167	Monodelphis domestica	67.97	0.00e+00	1151.00
IUUC-Mmu-063298	Mus musculus	85.07	0.00e+00	988.00
IUUC-Mpu-066195	Mustela putorius furo	84.10	0.00e+00	982.00
IUUC-Mlu-067583	Myotis lucifugus	78.01	8.00e-177	614.00
IUUC-Opr-070454	Ochotona princeps	89.60	6.00e-154	538.00
IUUC-Oga-088593	Otolemur garnettii	81.28	0.00e+00	1291.00
IUUC-Oar-090140	Ovis aries	84.04	0.00e+00	967.00
IUUC-Pan-092168	Papio anubis	80.55	0.00e+00	1245.00
IUUC-Psi-093707	Pelodiscus sinensis	60.68	0.00e+00	1036.00
IUUC-Pab-097614	Pongo abelii	84.98	0.00e+00	984.00
IUUC-Pca-100683	Procavia capensis	80.77	0.00e+00	922.00
IUUC-Pva-103146	Pteropus vampyrus	73.10	0.00e+00	827.00
IUUC-Rno-105061	Rattus norvegicus	83.49	0.00e+00	983.00
IUUC-Sha-106686	Sarcophilus harrisii	66.21	0.00e+00	818.00
IUUC-Tgu-117024	Taeniopygia guttata	62.45	0.00e+00	1042.00
IUUC-Tsy-119505	Tarsius syrichta	79.10	2.00e-139	489.00
IUUC-Tbe-127723	Tupaia belangeri	90.95	2.00e-82	299.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence