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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063865
UUCD1 version UUC-MuM-00451
Ensembl Protein ID ENSMUSP00000051080.5
UniProt Accession Q5SQM0; Q8C4R3; Q8C7L3; Q8R1E3; EMAL6_MOUSE
Genbank Protein ID CAI24269.1; CAI24269.1; CAI24269.1; CAI24365.1; CAI24365.1; CAI24365.1; CAI26026.1; CAI26026.1; CAI26026.1; BAC34015.1; BAC38214.1; AAH24726.1
Protein Name Echinoderm microtubule-associated protein-like 6; Echinoderm microtubule-associated protein-like 5-like
Genbank Nucleotide ID AL929371; AL731792; BX005100; AL731792; AL929371; BX005100; BX005100; AL731792; AL929371; AK049977; AK081418; BC024726
Gene Name Eml6; Eml5l
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000044072.14 ENSMUST00000058902.5 ENSMUSP00000051080.5
ENSMUSG00000044072.14 ENSMUST00000137689.2 ENSMUSP00000116197.2
ENSMUSG00000044072.14 ENSMUST00000109452.2 ENSMUSP00000105078.2
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RAID2
Post-translational Modifications (PTMs)
dbPAFPhosphositePlus
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.70e-61 202.5 105 144
UBD/Beta-Prp 1.80e-134 448.8 725 944
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf.sd.tllvsGsdD..gtikvWDlrtgvllk 37
           Ht +v claf sd  +l+s + D  +t+ +WD+r+g+ll 
   Q: 105  HTHGVACLAFdSDgQHLASVGLDakNTVCIWDWRKGKLLA 144
           99*********999*******9999***********9875 PP
   

   UBD/Beta-Prp
   S: 7    ghhksvitcvkfspdksllatg..srdgtikvwdvttgkllrslsg.heaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtl 90
           gh+++ ++ ++++p k+++atg  +rd+ + vwd++t k+l+ l+g h+ +v a++fs dgk lv+++ D  + +  wd ++g+ + t 
   Q: 725  GHDDDILS-LTIHPVKDYVATGqvGRDAAVHVWDTQTLKCLSLLKGhHQRGVCALDFSADGKCLVSVGLDdfHSVVFWDWKKGEKIATT 812
           45555555.999*********95569******************6615779*******************65566669*********** PP
   S: 91   kghedsvlslsfspsg.dklvsGshdrtirvwdletgqclee....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrt 174
           +gh+d++  ++ +p+  dklv+ +  + i+ w+   g   ++      +g+ ++ +cv++   ++l++sG++ + + +W  k   ll+t
   Q: 813  RGHKDKIFVVKCNPQHaDKLVTVG-IKHIKFWQQAGGGFTSKrgsfGSAGKLETMMCVSYGRMEDLVFSGAATGDIFIW--KDVLLLKT 898
           **************7757777776.9******98888888779999999******************************..8899**** PP
   S: 175  ltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtd 223
            +  h+++v  +   +  k +v+g++dg v+lwd   ++c++t+   ++
   Q: 899  VKA-HDGPVFAMYALD--KGFVTGGKDGIVELWDDMFERCLKTYAIKRT 944
           *98.*******99888..57**********************9976664 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.
 May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.
Protein Sequence
(Fasta)
MADRTAPRCQ LRLEWVYGYR GHQCRNNLYY TAGKEVVYFV AGVGVVYNTR EHSQKFFLGH 60
NDDIISLALH PDKTLIATGQ VGKEPYICIW NSYNVHTVSI LKDVHTHGVA CLAFDSDGQH 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063865|E3,WD_repeat;UBD,Beta-Prp|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCCCCTGGAG CCAGGGAAGG AGGAAGAGCT GGTCCCCAGA TCCCCGGTGA CGAAACCTAA 60
CCCGGGAGCG CGGGGAGGGA GGGAGGGCAG GCAGAGGATT TCGCTGGCTG GTGCGAGATC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063865|E3,WD_repeat;UBD,Beta-Prp|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR024977--Apc4_WD40_dom
IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005874--C:microtubule
GO:0015630--C:microtubule cytoskeleton
GO:0008017--F:microtubule binding
KEGG mmu:237711
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001387 Ailuropoda melanoleuca 96.78 0.00e+00 3820.00
IUUC-Apl-003604 Anas platyrhynchos 93.23 0.00e+00 3671.00
IUUC-Aca-004572 Anolis carolinensis 89.30 0.00e+00 3572.00
IUUC-Ame-010713 Astyanax mexicanus 79.98 0.00e+00 3208.00
IUUC-Bta-012812 Bos taurus 96.53 0.00e+00 3809.00
IUUC-Cja-019191 Callithrix jacchus 96.44 0.00e+00 3783.00
IUUC-Cfa-020041 Canis familiaris 96.89 0.00e+00 3548.00
IUUC-Cre-022931 Chlamydomonas reinhardtii 34.47 5.00e-100 361.00
IUUC-Csa-023689 Chlorocebus sabaeus 95.87 0.00e+00 3690.00
IUUC-Cho-025038 Choloepus hoffmanni 95.56 0.00e+00 1470.00
IUUC-Cin-025205 Ciona intestinalis 61.72 0.00e+00 2576.00
IUUC-Csv-026014 Ciona savignyi 63.09 0.00e+00 2598.00
IUUC-Dno-029982 Dasypus novemcinctus 94.86 0.00e+00 3638.00
IUUC-Eca-034161 Equus caballus 95.32 0.00e+00 3648.00
IUUC-Fca-036307 Felis catus 96.88 0.00e+00 3817.00
IUUC-Fal-037332 Ficedula albicollis 91.62 0.00e+00 3585.00
IUUC-Gmo-039057 Gadus morhua 74.83 0.00e+00 2989.00
IUUC-Gac-042555 Gasterosteus aculeatus 80.14 0.00e+00 3229.00
IUUC-Ggo-045107 Gorilla gorilla 97.14 0.00e+00 3831.00
IUUC-Hsa-046482 Homo sapiens 97.09 0.00e+00 3830.00
IUUC-Itr-049023 Ictidomys tridecemlineatus 95.32 0.00e+00 3696.00
IUUC-Loc-052642 Lepisosteus oculatus 87.63 0.00e+00 3464.00
IUUC-Laf-053649 Loxodonta africana 94.85 0.00e+00 3704.00
IUUC-Mcc-055361 Macaca mulatta 96.79 0.00e+00 3352.00
IUUC-Meu-056618 Macropus eugenii 77.62 0.00e+00 1784.00
IUUC-Mga-059202 Meleagris gallopavo 92.10 0.00e+00 3554.00
IUUC-Mmr-060729 Microcebus murinus 94.56 0.00e+00 3788.00
IUUC-Mdo-062462 Monodelphis domestica 94.51 0.00e+00 3645.00
IUUC-Mpu-066724 Mustela putorius furo 97.09 0.00e+00 3826.00
IUUC-Mlu-067816 Myotis lucifugus 96.49 0.00e+00 3820.00
IUUC-Opr-070213 Ochotona princeps 93.76 0.00e+00 1986.00
IUUC-Ont-071928 Oreochromis niloticus 78.93 0.00e+00 3231.00
IUUC-Oan-073563 Ornithorhynchus anatinus 94.09 0.00e+00 3724.00
IUUC-Ocu-074531 Oryctolagus cuniculus 96.83 0.00e+00 3815.00
IUUC-Ola-086943 Oryzias latipes 78.28 0.00e+00 3130.00
IUUC-Olu-087860 Ostreococcus lucimarinus 39.27 2.00e-116 412.00
IUUC-Oga-088665 Otolemur garnettii 95.80 0.00e+00 3669.00
IUUC-Oar-090429 Ovis aries 96.78 0.00e+00 3818.00
IUUC-Ptr-091168 Pan troglodytes 88.29 0.00e+00 3410.00
IUUC-Pan-092788 Papio anubis 96.67 0.00e+00 3034.00
IUUC-Psi-093281 Pelodiscus sinensis 91.45 0.00e+00 3631.00
IUUC-Pma-094424 Petromyzon marinus 72.46 3.00e-125 441.00
IUUC-Pab-098561 Pongo abelii 95.95 0.00e+00 3317.00
IUUC-Pca-100107 Procavia capensis 61.68 0.00e+00 1963.00
IUUC-Rno-105002 Rattus norvegicus 97.75 0.00e+00 3875.00
IUUC-Sha-107105 Sarcophilus harrisii 91.94 0.00e+00 3522.00
IUUC-Sar-113401 Sorex araneus 65.09 0.00e+00 1430.00
IUUC-Ssc-116282 Sus scrofa 96.83 0.00e+00 3715.00
IUUC-Tgu-116807 Taeniopygia guttata 92.95 0.00e+00 3663.00
IUUC-Tru-118040 Takifugu rubripes 78.47 0.00e+00 3165.00
IUUC-Tni-120118 Tetraodon nigroviridis 76.14 0.00e+00 3144.00
Created Date 25-Jun-2017

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