iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cja-019728

Ensembl Protein ID

ENSCJAP00000044197.1

UniProt Accession

F7FK44; F7FK44_CALJA

Genbank Protein ID

JAB04686.1; JAB16568.1; JAB33239.1; JAB38109.1; JAB44422.1

Protein Name

E3 ubiquitin-protein ligase ARIH2

Genbank Nucleotide ID

ACFV01038960; GAMS01006568; GAMR01000693; GAMQ01003742; GAMP01008333

Gene Name

ARIH2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000003305.2	ENSCJAT00000006395.2	ENSCJAP00000006061.2
ENSCJAG00000003305.2	ENSCJAT00000053332.1	ENSCJAP00000050015.1
ENSCJAG00000003305.2	ENSCJAT00000059300.1	ENSCJAP00000044197.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	1.10e-55	189.2	138	325

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpekleeseikellveeelykryekllleevveadaalkw 90
           C+vC+ ++  +e++ +l+C+h+fC++C++q++++ +k+g  + +sc+a++cp +++e+ +  ll++eel ++y+++l++++ve++++l++
   Q: 138  CAVCM-QFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFVFPLLPNEELREKYRRYLFRDYVESHYQLQL 226
           9***9.77777888899************************************************************************* PP
   S: 91   cpapdCslvvllekeaeklevecekcgkefCveCkeewHeglsCkelkeklakteeekeeaeskelleanskkCpkCkvyieknegCnhm 180
           cp +dC +v+++++  ++ +v+c++c+++fC++C++++H++++C +++++l+k++   +++e++++++a++k+CpkC+++iekn+gCnhm
   Q: 227  CPGADCPMVIRVQEP-RARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLTKCA---DDSETANYISAHTKDCPKCNICIEKNGGCNHM 312
           **************7.99*************************************...99****************************** PP
   S: 181  tCakCkaefCwlC 193
           +C+kCk++fCw+C
   Q: 313  QCSKCKHDFCWMC 325
           ************* PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MSVDMNSQGS DSNEEDYDPN CEEEEEEDED PGDIEDYYVG VASDVEQQGA DAFDPEEYQF 60
TCLTYKESEG ALNEHMTSLA SVLKVSHSVA KLILVNFHWQ VSEILDRYKS NSAQLLVEAR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGGAGACCA CTCCTGTGGA GGAAGCAGCG CGGGCTTGAC CGGCGTCGGC TCGCCGCCTC 60
TGCCGCTGCT GTGCCCCAGT CCGATCTCTC TGGCCCGGCC TGACCCGGTC TGGCTCGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01485--IBR

SMART

SM00647--IBR
SM00184--RING

Gene Ontology

GO:0031466--C:Cul5-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0005654--C:nucleoplasm
GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0048588--P:developmental cell growth
GO:0071425--P:hematopoietic stem cell proliferation
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

cjc:100385886

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001557	Ailuropoda melanoleuca	98.37	0.00e+00	935.00
IUUC-Atr-002495	Amborella trichopoda	30.65	2.00e-50	193.00
IUUC-Apl-003878	Anas platyrhynchos	93.50	0.00e+00	878.00
IUUC-Aca-004865	Anolis carolinensis	92.68	0.00e+00	882.00
IUUC-Ago-007926	Ashbya gossypii	25.94	1.00e-43	171.00
IUUC-Bta-012901	Bos taurus	98.17	0.00e+00	931.00
IUUC-Bdi-015065	Brachypodium distachyon	28.84	9.00e-56	211.00
IUUC-Bra-017081	Brassica rapa	29.36	8.00e-58	218.00
IUUC-Cel-018334	Caenorhabditis elegans	48.86	2.00e-127	449.00
IUUC-Cfa-020953	Canis familiaris	98.58	0.00e+00	935.00
IUUC-Cpo-021445	Cavia porcellus	98.98	0.00e+00	939.00
IUUC-Csa-023769	Chlorocebus sabaeus	97.36	0.00e+00	938.00
IUUC-Cho-024650	Choloepus hoffmanni	85.60	0.00e+00	786.00
IUUC-Cin-025577	Ciona intestinalis	54.55	8.00e-144	503.00
IUUC-Csv-025849	Ciona savignyi	55.84	2.00e-120	425.00
IUUC-Dre-028490	Danio rerio	79.80	0.00e+00	779.00
IUUC-Dno-029942	Dasypus novemcinctus	96.15	0.00e+00	927.00
IUUC-Dor-030134	Dipodomys ordii	84.98	3.00e-151	527.00
IUUC-Dme-031853	Drosophila melanogaster	55.06	9.00e-150	523.00
IUUC-Ete-032355	Echinops telfairi	88.87	0.00e+00	833.00
IUUC-Eca-033440	Equus caballus	98.58	0.00e+00	936.00
IUUC-Eeu-035230	Erinaceus europaeus	89.36	2.00e-115	408.00
IUUC-Fca-036308	Felis catus	92.29	0.00e+00	864.00
IUUC-Fal-036974	Ficedula albicollis	93.50	0.00e+00	878.00
IUUC-Fox-037790	Fusarium oxysporum	41.79	2.00e-59	222.00
IUUC-Gmo-038642	Gadus morhua	81.31	0.00e+00	780.00
IUUC-Gga-041019	Gallus gallus	93.50	0.00e+00	878.00
IUUC-Gac-042014	Gasterosteus aculeatus	80.28	0.00e+00	803.00
IUUC-Ggo-045329	Gorilla gorilla	97.77	0.00e+00	939.00
IUUC-Hsa-046712	Homo sapiens	98.17	0.00e+00	939.00
IUUC-Hvu-047322	Hordeum vulgare	30.67	1.00e-53	204.00
IUUC-Itr-048370	Ictidomys tridecemlineatus	98.80	0.00e+00	841.00
IUUC-Kpa-049350	Komagataella pastoris	28.20	5.00e-52	198.00
IUUC-Lch-049584	Latimeria chalumnae	86.00	0.00e+00	818.00
IUUC-Lpe-051492	Leersia perrieri	28.97	1.00e-56	214.00
IUUC-Loc-051826	Lepisosteus oculatus	79.62	9.00e-164	569.00
IUUC-Laf-054567	Loxodonta africana	96.95	0.00e+00	918.00
IUUC-Mcc-054919	Macaca mulatta	97.36	0.00e+00	938.00
IUUC-Meu-056332	Macropus eugenii	89.05	0.00e+00	846.00
IUUC-Mga-060132	Meleagris gallopavo	93.32	0.00e+00	878.00
IUUC-Mmr-061599	Microcebus murinus	93.32	0.00e+00	885.00
IUUC-Mdo-062186	Monodelphis domestica	94.93	0.00e+00	801.00
IUUC-Mmu-064271	Mus musculus	97.97	0.00e+00	933.00
IUUC-Mpu-066827	Mustela putorius furo	96.43	0.00e+00	826.00
IUUC-Mlu-067528	Myotis lucifugus	97.36	0.00e+00	893.00
IUUC-Nle-068995	Nomascus leucogenys	97.77	0.00e+00	939.00
IUUC-Opr-070518	Ochotona princeps	96.35	0.00e+00	897.00
IUUC-Ont-071650	Oreochromis niloticus	83.27	0.00e+00	822.00
IUUC-Oan-073676	Ornithorhynchus anatinus	93.87	0.00e+00	753.00
IUUC-Ocu-073761	Oryctolagus cuniculus	97.36	0.00e+00	937.00
IUUC-Obr-076705	Oryza brachyantha	30.05	1.00e-58	220.00
IUUC-Ogu-079025	Oryza glumaepatula	28.50	3.00e-56	213.00
IUUC-Opu-084059	Oryza punctata	29.21	3.00e-57	216.00
IUUC-Oru-084181	Oryza rufipogon	28.50	2.00e-56	213.00
IUUC-Osa-086069	Oryza sativa	28.50	5.00e-56	212.00
IUUC-Ola-087204	Oryzias latipes	79.57	0.00e+00	794.00
IUUC-Olu-087826	Ostreococcus lucimarinus	30.85	1.00e-45	177.00
IUUC-Oga-088098	Otolemur garnettii	96.55	0.00e+00	927.00
IUUC-Oar-089205	Ovis aries	98.17	0.00e+00	931.00
IUUC-Ptr-091514	Pan troglodytes	97.77	0.00e+00	939.00
IUUC-Pan-092493	Papio anubis	92.64	0.00e+00	893.00
IUUC-Psi-093024	Pelodiscus sinensis	87.84	5.00e-118	416.00
IUUC-Ppa-095554	Physcomitrella patens	29.10	2.00e-57	216.00
IUUC-Pfo-097256	Poecilia formosa	82.04	0.00e+00	810.00
IUUC-Pab-098504	Pongo abelii	90.06	0.00e+00	839.00
IUUC-Pop-099547	Populus trichocarpa	31.09	7.00e-56	211.00
IUUC-Pca-100700	Procavia capensis	89.25	0.00e+00	830.00
IUUC-Pva-103105	Pteropus vampyrus	97.56	0.00e+00	920.00
IUUC-Rno-105289	Rattus norvegicus	98.17	0.00e+00	935.00
IUUC-Sce-106154	Saccharomyces cerevisiae	28.01	6.00e-50	191.00
IUUC-Sha-107417	Sarcophilus harrisii	93.10	0.00e+00	868.00
IUUC-Sit-110645	Setaria italica	30.65	5.00e-55	209.00
IUUC-Sar-113042	Sorex araneus	95.98	0.00e+00	927.00
IUUC-Ssc-115362	Sus scrofa	98.78	0.00e+00	936.00
IUUC-Tgu-117469	Taeniopygia guttata	93.18	0.00e+00	829.00
IUUC-Tru-117976	Takifugu rubripes	80.39	0.00e+00	815.00
IUUC-Tsy-118876	Tarsius syrichta	82.19	1.00e-91	330.00
IUUC-Tni-119831	Tetraodon nigroviridis	80.20	0.00e+00	795.00
IUUC-Tca-121326	Theobroma cacao	28.67	3.00e-58	219.00
IUUC-Tae-123545	Triticum aestivum	29.88	5.00e-57	215.00
IUUC-Tur-126320	Triticum urartu	29.46	4.00e-43	169.00
IUUC-Tbe-127386	Tupaia belangeri	89.06	4.00e-159	554.00
IUUC-Ttr-128315	Tursiops truncatus	98.37	0.00e+00	934.00
IUUC-Vpa-130383	Vicugna pacos	90.85	0.00e+00	834.00
IUUC-Vvi-131543	Vitis vinifera	30.12	1.00e-55	211.00
IUUC-Xtr-132945	Xenopus tropicalis	90.65	0.00e+00	876.00
IUUC-Xma-134312	Xiphophorus maculatus	80.19	0.00e+00	804.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence