iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-010753

Ensembl Protein ID

ENSAMXP00000006986.1

UniProt Accession

W5KHC4; W5KHC4_ASTMX

Genbank Protein ID

ENSAMXP00000006986

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01075014

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000006771.1	ENSAMXT00000006986.1	ENSAMXP00000006986.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.00e-43	144.2	59	93
UBD/Beta-Prp	3.30e-61	207.3	27	257

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.....sdtllvsGsdDgtikvWDl 30
           gHt++v+++af     ++++ +s+sdD+++kvWD+
   Q: 59   GHTERVSGFAFcqhegQEHICASSSDDKSVKVWDT 93
           8***********9865446679999*********6 PP

UBD/Beta-Prp

   S: 25   latgsrdgtikvwdvttgkl.......lrslsgheaevtavkfspdgk...ilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfs 103
           ++  ++ +t+ + +vt  ++         +lsgh++ v+   f +++    i +++s+D+ +kvwd ++   +   ++h++ ++sl++s
   Q: 27   VLGFGAKSTVYLLKVTADSAavlgekpTGELSGHTERVSGFAFCQHEGqehICASSSDDKSVKVWDTEQKAVLAEHSAHQNIITSLHWS 115
           55556688888888888888888998999**********999977766688************************************** PP
   S: 104  p.sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl.ktgkllrtltgghtdsvyslsfd 189
           p ++  +vsG++  ++ ++ + ++  ++  + ++ +++ c++ +p + n ++ G +D+++ l d+ k g+++++l+g h++ ++ l++ 
   Q: 116  PvEKGLVVSGDEKGIVVCF-WYSRNDIH-SFFPEPRTIFCLACSPHNeNHVAVGYKDGMIVLIDIsKKGEVIHRLRG-HDEEIHALAWC 201
           *999**************6.56666677.6888888899999888888*****************999********9.*********88 PP
   S: 190  sng..........................kelvsgsldgtvklwdlqtgecvrtln 219
           ++                            +l+sgs+d+tv++w+  +g+ v+tl+
   Q: 202  PEPkeedlycfrpadstdasnglteieggGYLASGSRDQTVRIWSTARGKGVMTLK 257
           887888888888888999999****************************9999875 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

LRMHERLLPA SPNWYCSRCS DVNSSGVLGF GAKSTVYLLK VTADSAAVLG EKPTGELSGH 60
TERVSGFAFC QHEGQEHICA SSSDDKSVKV WDTEQKAVLA EHSAHQNIIT SLHWSPVEKG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCAGAATGC ACGAGAGGCT TCTTCCAGCT TCTCCGAACT GGTACTGCTC CCGCTGCAGT 60
GATGTGAACA GTAGCGGAGT GCTGGGCTTT GGGGCTAAAA GCACAGTTTA CCTGCTGAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR020472--G-protein_beta_WD-40_rep
IPR011047--Quinoprotein_ADH-like_supfam
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001199	Ailuropoda melanoleuca	50.66	0.00e+00	1494.00
IUUC-Apl-003586	Anas platyrhynchos	49.96	0.00e+00	1318.00
IUUC-Aca-004956	Anolis carolinensis	51.21	0.00e+00	1521.00
IUUC-Bta-012315	Bos taurus	51.41	0.00e+00	1495.00
IUUC-Cja-019334	Callithrix jacchus	50.66	0.00e+00	1520.00
IUUC-Cfa-021254	Canis familiaris	50.83	0.00e+00	1517.00
IUUC-Cpo-021984	Cavia porcellus	49.67	0.00e+00	1405.00
IUUC-Csa-023650	Chlorocebus sabaeus	50.26	0.00e+00	1492.00
IUUC-Cho-024860	Choloepus hoffmanni	55.18	0.00e+00	1304.00
IUUC-Cin-025778	Ciona intestinalis	40.28	7.00e-152	531.00
IUUC-Csv-026313	Ciona savignyi	39.92	2.00e-157	549.00
IUUC-Dre-028096	Danio rerio	80.81	0.00e+00	1228.00
IUUC-Dno-029799	Dasypus novemcinctus	55.65	0.00e+00	1407.00
IUUC-Dor-030885	Dipodomys ordii	50.14	0.00e+00	728.00
IUUC-Dme-031744	Drosophila melanogaster	35.35	1.00e-11	65.90
IUUC-Ete-032918	Echinops telfairi	48.74	0.00e+00	1411.00
IUUC-Eca-034144	Equus caballus	50.30	0.00e+00	1467.00
IUUC-Eeu-034843	Erinaceus europaeus	47.95	0.00e+00	1048.00
IUUC-Fca-035948	Felis catus	50.10	0.00e+00	1476.00
IUUC-Fal-037303	Ficedula albicollis	51.03	0.00e+00	1492.00
IUUC-Gmo-039591	Gadus morhua	62.57	0.00e+00	968.00
IUUC-Gga-040570	Gallus gallus	49.82	0.00e+00	1297.00
IUUC-Gac-042646	Gasterosteus aculeatus	56.95	0.00e+00	1579.00
IUUC-Ggo-045605	Gorilla gorilla	50.00	0.00e+00	1127.00
IUUC-Hsa-046122	Homo sapiens	50.89	0.00e+00	1504.00
IUUC-Itr-048094	Ictidomys tridecemlineatus	55.04	0.00e+00	1402.00
IUUC-Lch-050489	Latimeria chalumnae	47.32	0.00e+00	850.00
IUUC-Loc-052259	Lepisosteus oculatus	68.05	0.00e+00	1066.00
IUUC-Laf-053338	Loxodonta africana	51.09	0.00e+00	1503.00
IUUC-Mcc-055442	Macaca mulatta	50.43	0.00e+00	1499.00
IUUC-Meu-056245	Macropus eugenii	63.96	0.00e+00	675.00
IUUC-Mga-060202	Meleagris gallopavo	50.75	0.00e+00	1372.00
IUUC-Mmr-061730	Microcebus murinus	49.90	0.00e+00	1473.00
IUUC-Mdo-062880	Monodelphis domestica	50.65	0.00e+00	1503.00
IUUC-Mmu-063930	Mus musculus	60.51	0.00e+00	1016.00
IUUC-Mpu-066605	Mustela putorius furo	50.76	0.00e+00	1504.00
IUUC-Mlu-067765	Myotis lucifugus	51.02	0.00e+00	1509.00
IUUC-Nle-069183	Nomascus leucogenys	50.40	0.00e+00	1472.00
IUUC-Opr-070659	Ochotona princeps	37.75	1.00e-142	501.00
IUUC-Ont-072356	Oreochromis niloticus	57.84	0.00e+00	1677.00
IUUC-Oan-073056	Ornithorhynchus anatinus	53.42	0.00e+00	1483.00
IUUC-Ocu-073881	Oryctolagus cuniculus	50.39	0.00e+00	1535.00
IUUC-Ola-087120	Oryzias latipes	62.50	7.00e-73	266.00
IUUC-Olu-087648	Ostreococcus lucimarinus	25.65	3.00e-31	130.00
IUUC-Oga-088343	Otolemur garnettii	51.02	0.00e+00	1498.00
IUUC-Oar-089257	Ovis aries	51.52	0.00e+00	1504.00
IUUC-Ptr-090497	Pan troglodytes	50.63	0.00e+00	1496.00
IUUC-Pan-092638	Papio anubis	50.43	0.00e+00	1489.00
IUUC-Psi-093096	Pelodiscus sinensis	51.27	0.00e+00	1300.00
IUUC-Pma-094571	Petromyzon marinus	38.72	2.00e-69	256.00
IUUC-Pfo-096348	Poecilia formosa	71.45	0.00e+00	1069.00
IUUC-Pab-098153	Pongo abelii	50.33	0.00e+00	1515.00
IUUC-Pca-100957	Procavia capensis	48.48	0.00e+00	1393.00
IUUC-Pva-102439	Pteropus vampyrus	50.26	0.00e+00	1511.00
IUUC-Rno-105891	Rattus norvegicus	49.27	0.00e+00	1387.00
IUUC-Sha-107181	Sarcophilus harrisii	65.97	0.00e+00	1006.00
IUUC-Ssc-115413	Sus scrofa	51.03	0.00e+00	1531.00
IUUC-Tgu-117082	Taeniopygia guttata	52.21	0.00e+00	1475.00
IUUC-Tru-118491	Takifugu rubripes	69.04	0.00e+00	1057.00
IUUC-Tsy-119629	Tarsius syrichta	64.71	1.00e-114	408.00
IUUC-Tni-120240	Tetraodon nigroviridis	68.03	0.00e+00	1027.00
IUUC-Tbe-127673	Tupaia belangeri	48.12	0.00e+00	1147.00
IUUC-Ttr-128562	Tursiops truncatus	48.55	0.00e+00	1420.00
IUUC-Vpa-130596	Vicugna pacos	52.82	0.00e+00	1191.00
IUUC-Xtr-132469	Xenopus tropicalis	49.90	0.00e+00	1423.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence