iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gga-041254

Ensembl Protein ID

ENSGALP00000024312.4

UniProt Accession

Q8AXV1; SH3G2_CHICK

Genbank Protein ID

CAD27935.1

Protein Name

Endophilin-A1; Endophilin-1; SH3 domain-containing GRB2-like protein 1; SH3p4

Genbank Nucleotide ID

AJ439350

Gene Name

SH3GL2; SH3P4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000015096.6	ENSGALT00000024358.6	ENSGALP00000024312.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.00e-15	55.9	295	346

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
            +++lyd+e++n++eL +k+Gd++++   ++ de+W +g   l+g++G+fP n+v 
   Q: 295  CCRALYDFEPENEGELGFKEGDIITLT--NQIDENWYEG--MLHGQSGFFPINYVD 346
           699***********************7..99********..8************96 PP

Organism

Gallus gallus

Functional Description
(View)

Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature (By similarity).

Protein Sequence
(Fasta)

MSVAGLKKQF HKATQKVSEK VGGAEGTKLD DDFKEMERKV DVTSRAVMEI MAKTIEYLQP 60
NPASRAKLSM INTMSKIRGQ EKGPGYPQAE ALLADAMLKF GRELGEECNF GPALADVGEA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCATCGCGCC GCCCTCGCCA TGTCGGTGGC CGGGCTCAAG AAGCAGTTCC ATAAAGCGAC 60
CCAGGTACCG CCTCGGCCCC CCGCGCCGCG AGGGCCGTGC GCGGGTGCGT GGAGCGCGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0254--Endocytosis
KW-0446--Lipid-binding
KW-0472--Membrane
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR027267--AH/BAR-dom
IPR004148--BAR_dom
IPR001452--SH3_domain

PROSITE

PS51021--BAR
PS50002--SH3

Pfam

PF03114--BAR
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00721--BAR
SM00326--SH3

Gene Ontology

GO:0005769--C:early endosome
GO:0070062--C:extracellular exosome
GO:0016020--C:membrane
GO:0045202--C:synapse
GO:0008289--F:lipid binding
GO:1990416--P:cellular response to brain-derived neurotrophic factor stimulus
GO:0097484--P:dendrite extension
GO:0002090--P:regulation of receptor internalization
GO:0016191--P:synaptic vesicle uncoating

KEGG

gga:395203

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001915	Ailuropoda melanoleuca	91.42	0.00e+00	645.00
IUUC-Apl-003760	Anas platyrhynchos	91.37	0.00e+00	690.00
IUUC-Aca-004816	Anolis carolinensis	89.49	0.00e+00	664.00
IUUC-Ame-011714	Astyanax mexicanus	80.17	3.00e-171	593.00
IUUC-Bta-012465	Bos taurus	91.50	0.00e+00	673.00
IUUC-Cja-019054	Callithrix jacchus	90.37	0.00e+00	667.00
IUUC-Cfa-020276	Canis familiaris	90.88	6.00e-175	605.00
IUUC-Cpo-021492	Cavia porcellus	91.74	0.00e+00	647.00
IUUC-Csa-023432	Chlorocebus sabaeus	89.31	2.00e-172	597.00
IUUC-Cho-024348	Choloepus hoffmanni	91.78	0.00e+00	677.00
IUUC-Dre-028301	Danio rerio	75.92	1.00e-157	548.00
IUUC-Dno-029915	Dasypus novemcinctus	90.43	2.00e-165	574.00
IUUC-Dor-030855	Dipodomys ordii	81.36	2.00e-163	568.00
IUUC-Ete-032686	Echinops telfairi	82.25	3.00e-164	570.00
IUUC-Eca-033814	Equus caballus	91.15	0.00e+00	644.00
IUUC-Eeu-034924	Erinaceus europaeus	89.80	0.00e+00	658.00
IUUC-Fca-035895	Felis catus	91.12	0.00e+00	644.00
IUUC-Fal-037607	Ficedula albicollis	97.73	0.00e+00	714.00
IUUC-Gac-041419	Gasterosteus aculeatus	79.59	1.00e-157	548.00
IUUC-Ggo-045606	Gorilla gorilla	90.37	0.00e+00	667.00
IUUC-Hsa-046258	Homo sapiens	90.37	0.00e+00	667.00
IUUC-Lch-049520	Latimeria chalumnae	76.34	4.00e-139	487.00
IUUC-Loc-052760	Lepisosteus oculatus	81.32	1.00e-159	555.00
IUUC-Mcc-055545	Macaca mulatta	89.41	0.00e+00	636.00
IUUC-Meu-056119	Macropus eugenii	92.35	0.00e+00	684.00
IUUC-Mpo-057322	Magnaporthe poae	32.39	3.00e-12	67.80
IUUC-Mmr-061111	Microcebus murinus	89.37	0.00e+00	641.00
IUUC-Mdo-062217	Monodelphis domestica	92.35	0.00e+00	684.00
IUUC-Mmu-063284	Mus musculus	90.93	0.00e+00	670.00
IUUC-Mpu-066706	Mustela putorius furo	90.16	2.00e-172	597.00
IUUC-Mlu-067212	Myotis lucifugus	84.05	0.00e+00	633.00
IUUC-Ont-072622	Oreochromis niloticus	82.44	4.00e-175	606.00
IUUC-Oan-073674	Ornithorhynchus anatinus	90.86	0.00e+00	644.00
IUUC-Ocu-074005	Oryctolagus cuniculus	91.50	0.00e+00	673.00
IUUC-Ola-086840	Oryzias latipes	77.46	1.00e-157	548.00
IUUC-Oga-089025	Otolemur garnettii	87.75	0.00e+00	640.00
IUUC-Oar-089614	Ovis aries	91.15	0.00e+00	644.00
IUUC-Ptr-090943	Pan troglodytes	90.37	0.00e+00	667.00
IUUC-Pan-091990	Papio anubis	89.41	0.00e+00	636.00
IUUC-Psi-093052	Pelodiscus sinensis	89.52	0.00e+00	662.00
IUUC-Pva-102745	Pteropus vampyrus	91.22	0.00e+00	670.00
IUUC-Rno-105095	Rattus norvegicus	91.22	0.00e+00	672.00
IUUC-Sha-106694	Sarcophilus harrisii	89.77	0.00e+00	661.00
IUUC-Sar-113540	Sorex araneus	87.28	2.00e-175	607.00
IUUC-Ssc-116180	Sus scrofa	81.74	7.00e-160	556.00
IUUC-Tgu-117366	Taeniopygia guttata	98.02	0.00e+00	718.00
IUUC-Tru-118509	Takifugu rubripes	80.17	2.00e-171	594.00
IUUC-Vpa-130032	Vicugna pacos	77.71	2.00e-141	494.00
IUUC-Xtr-131877	Xenopus tropicalis	78.22	2.00e-160	558.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence