iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004418

UUCD1 version

UUC-AnC-00546

Ensembl Protein ID

ENSACAP00000004959.3

UniProt Accession

G1KDJ2; G1KDJ2_ANOCA

Protein Name

Uncharacterized protein

Gene Name

KLHL12

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000005031.3	ENSACAT00000005072.3	ENSACAP00000004959.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	6.10e-20	71.3	29	92
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	7.20e-14	50.7	128	159

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkl 65
           +Dv+l v++++f+ah+ivLaa+S++F a+f++el+e++ k+ v+i+++ ++ ++ ll+F+Yt ++
   Q: 29   CDVTLRVEQKYFPAHRIVLAACSDYFCAMFTSELSEKD-KPYVDIQGLTASTMEILLDFVYTETV 92
           9************************************9.***********************987 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Nclgi++fA++++c dL++aa+ f +khF+
   Q: 128  PSNCLGIRDFAETHNCVDLMQAAEVFSQKHFP 159
           89*****************************6 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MAPKDIMTNS HAKSILNAMN SLRKSNTLCD VTLRVEQKYF PAHRIVLAAC SDYFCAMFTS 60
ELSEKDKPYV DIQGLTASTM EILLDFVYTE TVHVTVENVQ ELLPAACLLQ LKGVKQACCE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTTGACTGA GGCCCCTTCC ACACAGCTGA ATAAAATCCC ACATTATCTG CTTTGAACTG 60
GAATATGTGG CAGTGTGGAC TCATATAACC CAGTTCAAAG CAGACGCTGT GGGATTTTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0030134--C:ER to Golgi transport vesicle
GO:0000139--C:Golgi membrane
GO:0005815--C:microtubule organizing center
GO:0048208--P:COPII vesicle coating
GO:0006513--P:protein monoubiquitination
GO:0016055--P:Wnt signaling pathway

KEGG

acs:100561958

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002301	Ailuropoda melanoleuca	95.71	0.00e+00	1094.00
IUUC-Apl-003339	Anas platyrhynchos	98.84	0.00e+00	1044.00
IUUC-Ath-007066	Arabidopsis thaliana	33.68	3.00e-40	160.00
IUUC-Ame-011906	Astyanax mexicanus	75.18	0.00e+00	871.00
IUUC-Bta-012979	Bos taurus	94.50	0.00e+00	1095.00
IUUC-Cja-019582	Callithrix jacchus	95.74	0.00e+00	1107.00
IUUC-Cfa-020716	Canis familiaris	96.28	0.00e+00	1114.00
IUUC-Cpo-022013	Cavia porcellus	96.45	0.00e+00	1116.00
IUUC-Csa-023424	Chlorocebus sabaeus	96.18	0.00e+00	1031.00
IUUC-Cho-024586	Choloepus hoffmanni	78.72	0.00e+00	872.00
IUUC-Dre-028344	Danio rerio	88.03	4.00e-165	573.00
IUUC-Dno-028854	Dasypus novemcinctus	96.28	0.00e+00	1114.00
IUUC-Dor-030403	Dipodomys ordii	96.10	0.00e+00	1110.00
IUUC-Ete-032963	Echinops telfairi	94.43	0.00e+00	966.00
IUUC-Eca-033282	Equus caballus	96.10	0.00e+00	1113.00
IUUC-Eeu-034933	Erinaceus europaeus	95.29	3.00e-139	488.00
IUUC-Fca-035487	Felis catus	96.28	0.00e+00	1114.00
IUUC-Fal-037059	Ficedula albicollis	98.40	0.00e+00	1122.00
IUUC-Gmo-039564	Gadus morhua	89.01	0.00e+00	1073.00
IUUC-Gga-040629	Gallus gallus	98.40	0.00e+00	1127.00
IUUC-Gac-042526	Gasterosteus aculeatus	89.36	0.00e+00	1074.00
IUUC-Ggo-044839	Gorilla gorilla	96.28	0.00e+00	1114.00
IUUC-Hsa-046742	Homo sapiens	96.28	0.00e+00	1114.00
IUUC-Itr-048958	Ictidomys tridecemlineatus	96.10	0.00e+00	1111.00
IUUC-Lch-049540	Latimeria chalumnae	92.55	0.00e+00	1108.00
IUUC-Loc-051923	Lepisosteus oculatus	93.09	0.00e+00	1086.00
IUUC-Laf-054370	Loxodonta africana	96.10	0.00e+00	1113.00
IUUC-Mcc-054852	Macaca mulatta	96.28	0.00e+00	1114.00
IUUC-Mga-059486	Meleagris gallopavo	97.26	0.00e+00	1033.00
IUUC-Mmr-061777	Microcebus murinus	96.28	0.00e+00	1112.00
IUUC-Mdo-061990	Monodelphis domestica	95.92	0.00e+00	1109.00
IUUC-Mmu-064053	Mus musculus	95.74	0.00e+00	1112.00
IUUC-Mac-064654	Musa acuminata	33.68	7.00e-41	162.00
IUUC-Mpu-066623	Mustela putorius furo	82.18	0.00e+00	783.00
IUUC-Mlu-067648	Myotis lucifugus	95.57	0.00e+00	1134.00
IUUC-Nle-069714	Nomascus leucogenys	96.10	0.00e+00	1113.00
IUUC-Opr-071143	Ochotona princeps	89.54	0.00e+00	1015.00
IUUC-Ont-071848	Oreochromis niloticus	90.25	0.00e+00	1084.00
IUUC-Oan-073041	Ornithorhynchus anatinus	94.96	4.00e-158	550.00
IUUC-Ocu-074379	Oryctolagus cuniculus	95.74	0.00e+00	1110.00
IUUC-Ola-087469	Oryzias latipes	89.89	0.00e+00	1081.00
IUUC-Oar-090144	Ovis aries	95.57	0.00e+00	1107.00
IUUC-Ptr-091406	Pan troglodytes	96.28	0.00e+00	1114.00
IUUC-Pan-092762	Papio anubis	95.22	0.00e+00	1094.00
IUUC-Psi-093391	Pelodiscus sinensis	97.70	0.00e+00	1125.00
IUUC-Pma-094134	Petromyzon marinus	74.36	0.00e+00	833.00
IUUC-Pfo-096404	Poecilia formosa	90.07	0.00e+00	1080.00
IUUC-Pab-098425	Pongo abelii	95.39	0.00e+00	1102.00
IUUC-Pca-101093	Procavia capensis	96.55	4.00e-168	584.00
IUUC-Pva-102239	Pteropus vampyrus	85.82	0.00e+00	996.00
IUUC-Rno-104921	Rattus norvegicus	95.92	0.00e+00	1114.00
IUUC-Sha-106625	Sarcophilus harrisii	96.81	0.00e+00	1117.00
IUUC-Sar-113468	Sorex araneus	84.17	0.00e+00	687.00
IUUC-Ssc-116106	Sus scrofa	95.92	0.00e+00	1110.00
IUUC-Tgu-117402	Taeniopygia guttata	68.07	0.00e+00	684.00
IUUC-Tru-117546	Takifugu rubripes	89.36	0.00e+00	1076.00
IUUC-Tsy-118802	Tarsius syrichta	86.52	0.00e+00	970.00
IUUC-Tni-119999	Tetraodon nigroviridis	89.64	0.00e+00	1070.00
IUUC-Tca-121074	Theobroma cacao	31.48	2.00e-38	154.00
IUUC-Tbe-127987	Tupaia belangeri	95.43	0.00e+00	928.00
IUUC-Ttr-128613	Tursiops truncatus	88.81	0.00e+00	1006.00
IUUC-Xtr-132401	Xenopus tropicalis	91.91	3.00e-173	600.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence