iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052688

Ensembl Protein ID

ENSLOCP00000020459.1

UniProt Accession

W5NIK0; W5NIK0_LEPOC

Genbank Protein ID

ENSLOCP00000020459

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01025826

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000016564.1	ENSLOCT00000020494.1	ENSLOCP00000020459.1
ENSLOCG00000016564.1	ENSLOCT00000020496.1	ENSLOCP00000020461.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.40e-52	179.2	30	339

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           Gl N   +C +NSvLQ+ ++++e++e l + + +++       e+k +   +lq++++ ++k++++  + r++l +l+  +  +  + +
   Q: 30   GLLNYRLSCCVNSVLQSFFATEEFTEKLDRwNGPSTA-----AEEKCNTPLQLQRVLRVMQKDRSQTQAHRDFLYCLHLNH-ALCINLK 112
           999***************************4334433.....357899*****************************9555.5678999 PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvs..sreepfldlslpv 176
           + + E+ +  l+ +++++                           ++   + i dl++ ++++++kcl+c++      ++ f++++l+v
   Q: 113  KKTLEVNRKQLNLIQQQM--------------------------SDTNLAQEIRDLYKTEVRQHLKCLSCNSMHdvPNNSYFVSFPLSV 175
           99****************..........................456677889******************999545666666777777 PP
   S: 177  pgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfc 265
            ++ +     +++c++ f+++++l+++nk+yc+ c +k+++e+ +kl++lP+vL++hLkRf  +++ +s +k+n kv+fp+ Ld ++ +
   Q: 176  YENCQ----MVENCFQFFFRPQKLTDRNKCYCNYCGEKKTTEQVFKLTSLPKVLVIHLKRF--QCS-GSTRKLNCKVSFPEILDFQKIL 257
           66664....6***************************************************..444.6788****************** PP
   S: 266  tspeekqke....kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg.....staYvlfYkr 337
           ++++ + k     +++YeL+av+vHsG++  GHY+ay+k+  ++ W++ dDs++++ ++++v+++ g     ++aY+l+Y++
   Q: 258  HEDQHELKCacfpQYIYELFAVIVHSGTAMFGHYTAYIKSPGEQtWYHADDSSISTASWADVKSTYGsssgsRSAYMLLYRK 339
           *977666559999***************************87778*******************888*************97 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

IGSNMLGRCF TRSYSFQDSM SSTRLPGLMG LLNYRLSCCV NSVLQSFFAT EEFTEKLDRW 60
NGPSTAAEEK CNTPLQLQRV LRVMQKDRSQ TQAHRDFLYC LHLNHALCIN LKKKTLEVNR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAAAGGGCA AGCACACAGT TATCCCATTT TTGAGGATGA AGTGGTGAGA AAAAACCCTA 60
TACTTATTTC GTTTTATCTT GTATATTATA TATTTAACCG AAATTCTAGT GGTGCAATAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001615	Ailuropoda melanoleuca	31.65	1.00e-44	173.00
IUUC-Apl-004006	Anas platyrhynchos	38.01	1.00e-55	209.00
IUUC-Aca-005088	Anolis carolinensis	33.02	4.00e-41	162.00
IUUC-Ame-010606	Astyanax mexicanus	45.37	4.00e-70	258.00
IUUC-Bta-013036	Bos taurus	34.05	2.00e-48	186.00
IUUC-Cja-019052	Callithrix jacchus	34.57	8.00e-48	184.00
IUUC-Cfa-020554	Canis familiaris	34.26	4.00e-50	191.00
IUUC-Cpo-022421	Cavia porcellus	34.97	1.00e-51	196.00
IUUC-Csa-023737	Chlorocebus sabaeus	38.12	2.00e-34	138.00
IUUC-Cho-024807	Choloepus hoffmanni	32.49	4.00e-21	95.50
IUUC-Dre-027408	Danio rerio	43.49	2.00e-68	252.00
IUUC-Dno-029813	Dasypus novemcinctus	28.26	8.00e-32	130.00
IUUC-Dor-030532	Dipodomys ordii	33.33	2.00e-45	176.00
IUUC-Ete-032254	Echinops telfairi	32.50	2.00e-46	179.00
IUUC-Eca-033482	Equus caballus	33.54	9.00e-50	190.00
IUUC-Eeu-034451	Erinaceus europaeus	35.94	5.00e-33	134.00
IUUC-Fca-036313	Felis catus	33.02	3.00e-47	182.00
IUUC-Fal-037216	Ficedula albicollis	36.99	6.00e-53	201.00
IUUC-Gmo-038649	Gadus morhua	41.01	3.00e-58	218.00
IUUC-Gga-041082	Gallus gallus	37.62	1.00e-51	196.00
IUUC-Gac-042439	Gasterosteus aculeatus	43.38	8.00e-71	260.00
IUUC-Ggo-044957	Gorilla gorilla	32.12	2.00e-38	152.00
IUUC-Hsa-046381	Homo sapiens	34.47	5.00e-50	191.00
IUUC-Itr-047918	Ictidomys tridecemlineatus	33.85	1.00e-48	187.00
IUUC-Laf-054109	Loxodonta africana	34.78	3.00e-52	199.00
IUUC-Mcc-054814	Macaca mulatta	35.09	1.00e-52	200.00
IUUC-Meu-056253	Macropus eugenii	33.92	8.00e-35	140.00
IUUC-Mmr-061613	Microcebus murinus	33.53	6.00e-49	187.00
IUUC-Mdo-061890	Monodelphis domestica	34.04	5.00e-48	184.00
IUUC-Mmu-064329	Mus musculus	32.81	8.00e-43	167.00
IUUC-Mpu-066342	Mustela putorius furo	33.54	5.00e-49	188.00
IUUC-Mlu-067010	Myotis lucifugus	33.54	2.00e-49	189.00
IUUC-Nle-069148	Nomascus leucogenys	34.16	6.00e-51	194.00
IUUC-Opr-070988	Ochotona princeps	40.41	1.00e-27	117.00
IUUC-Ont-072039	Oreochromis niloticus	45.95	1.00e-72	266.00
IUUC-Oan-073740	Ornithorhynchus anatinus	42.01	3.00e-30	125.00
IUUC-Ocu-074498	Oryctolagus cuniculus	33.85	1.00e-41	163.00
IUUC-Ola-086753	Oryzias latipes	43.75	3.00e-66	245.00
IUUC-Oga-088497	Otolemur garnettii	34.28	3.00e-50	192.00
IUUC-Oar-089505	Ovis aries	33.64	5.00e-48	184.00
IUUC-Ptr-091656	Pan troglodytes	34.78	7.00e-52	197.00
IUUC-Pan-092498	Papio anubis	35.09	8.00e-53	200.00
IUUC-Psi-093409	Pelodiscus sinensis	35.15	3.00e-49	188.00
IUUC-Pfo-096507	Poecilia formosa	41.74	8.00e-64	237.00
IUUC-Pab-097828	Pongo abelii	33.23	1.00e-49	190.00
IUUC-Pca-100299	Procavia capensis	30.21	5.00e-23	102.00
IUUC-Pva-102972	Pteropus vampyrus	32.19	1.00e-44	173.00
IUUC-Rno-105738	Rattus norvegicus	33.85	8.00e-47	181.00
IUUC-Sha-107309	Sarcophilus harrisii	34.31	2.00e-44	172.00
IUUC-Sar-112983	Sorex araneus	30.77	5.00e-38	151.00
IUUC-Ssc-116049	Sus scrofa	33.23	3.00e-50	191.00
IUUC-Tgu-117115	Taeniopygia guttata	37.30	4.00e-54	204.00
IUUC-Tru-118022	Takifugu rubripes	40.31	4.00e-58	218.00
IUUC-Tni-120306	Tetraodon nigroviridis	40.06	8.00e-59	220.00
IUUC-Tbe-127768	Tupaia belangeri	29.15	1.00e-26	114.00
IUUC-Ttr-128686	Tursiops truncatus	34.95	4.00e-48	185.00
IUUC-Xtr-132032	Xenopus tropicalis	33.44	2.00e-43	169.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence