iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090162

Ensembl Protein ID

ENSOARP00000019777.1

UniProt Accession

W5QAN2; W5QAN2_SHEEP

Genbank Protein ID

ENSOARP00000019777

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01023145

Gene Name

KDM5B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000018421.1	ENSOART00000020050.1	ENSOARP00000019777.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.80e-19	69.2	263	309

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           vCl+Cg+g++++  l+ C+ C++ +H  Cl ++   ++p+ + w CpkC 
   Q: 263  VCLLCGSGSDED-RLLLCDGCDDSYHTFCLIPP-LHDVPKGD-WRCPKCL 309
           8*********88.6*******************.*******7.******5 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MGGNTLVVRT APRPAPRLSQ DWQPPFACDV DKLHFTPRIQ RLNELEAQTR VKLNFLDQIA 60
KYWELQGSTL KIPHVERKIL DLFQLNKLVA EEGGFAVVCK DRKWTKIATK MGFAPGKAVG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTGCATATA AGTTAAATAA TCAGGGTGAC AATATACAGC CTTGACGTAC TCCTTTTTCT 60
ATTTGGAACC AGTCTGTTGT TCCATGTCCA GTTCTAACTG TTGCTTCCTG ACCTGCATAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001606--ARID_dom
IPR003347--JmjC_dom
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51011--ARID
PS51184--JMJC
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF01388--ARID
PF02373--JmjC
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2

SMART

SM00501--BRIGHT
SM00558--JmjC
SM00249--PHD

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0034648--F:histone demethylase activity (H3-dimethyl-K4 specific)
GO:0034647--F:histone demethylase activity (H3-trimethyl-K4 specific)
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0060444--P:branching involved in mammary gland duct morphogenesis
GO:0060763--P:mammary duct terminal end bud growth
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0010628--P:positive regulation of gene expression
GO:0033601--P:positive regulation of mammary gland epithelial cell proliferation
GO:0009791--P:post-embryonic development
GO:2000864--P:regulation of estradiol secretion
GO:0007338--P:single fertilization
GO:0061038--P:uterus morphogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000552	Aegilops tauschii	32.65	4.00e-99	357.00
IUUC-Aml-001963	Ailuropoda melanoleuca	91.06	0.00e+00	2640.00
IUUC-Apl-003770	Anas platyrhynchos	84.20	0.00e+00	2118.00
IUUC-Aca-004867	Anolis carolinensis	78.18	0.00e+00	2334.00
IUUC-Ath-007218	Arabidopsis thaliana	35.56	4.00e-09	58.50
IUUC-Ame-010620	Astyanax mexicanus	62.74	0.00e+00	1840.00
IUUC-Bta-012733	Bos taurus	96.82	0.00e+00	2805.00
IUUC-Bol-015336	Brassica oleracea	36.45	3.00e-14	75.50
IUUC-Cja-019050	Callithrix jacchus	90.57	0.00e+00	2666.00
IUUC-Cfa-021015	Canis familiaris	90.92	0.00e+00	2631.00
IUUC-Cpo-022340	Cavia porcellus	90.72	0.00e+00	2599.00
IUUC-Csa-023441	Chlorocebus sabaeus	91.17	0.00e+00	2633.00
IUUC-Cho-024823	Choloepus hoffmanni	96.14	0.00e+00	1610.00
IUUC-Cne-026851	Cryptococcus neoformans	28.83	2.00e-111	397.00
IUUC-Dre-027707	Danio rerio	60.16	0.00e+00	1752.00
IUUC-Dno-028978	Dasypus novemcinctus	90.37	0.00e+00	2622.00
IUUC-Dor-030854	Dipodomys ordii	81.69	0.00e+00	1818.00
IUUC-Ete-032760	Echinops telfairi	86.94	0.00e+00	1778.00
IUUC-Eca-034370	Equus caballus	91.60	0.00e+00	2575.00
IUUC-Eeu-035012	Erinaceus europaeus	73.72	0.00e+00	1812.00
IUUC-Fca-035494	Felis catus	91.33	0.00e+00	2632.00
IUUC-Fal-037631	Ficedula albicollis	80.30	0.00e+00	2337.00
IUUC-Gmo-039522	Gadus morhua	58.03	0.00e+00	1625.00
IUUC-Gga-040802	Gallus gallus	80.22	0.00e+00	2300.00
IUUC-Gac-041563	Gasterosteus aculeatus	60.41	0.00e+00	1750.00
IUUC-Gma-042675	Glycine max	33.25	2.00e-100	361.00
IUUC-Ggo-044856	Gorilla gorilla	74.81	0.00e+00	2020.00
IUUC-Hsa-045888	Homo sapiens	88.95	0.00e+00	2641.00
IUUC-Hvu-047583	Hordeum vulgare	43.04	1.00e-15	79.00
IUUC-Itr-048297	Ictidomys tridecemlineatus	91.17	0.00e+00	2604.00
IUUC-Lch-050483	Latimeria chalumnae	63.99	0.00e+00	1882.00
IUUC-Lpe-051537	Leersia perrieri	31.69	4.00e-91	330.00
IUUC-Loc-052550	Lepisosteus oculatus	69.24	0.00e+00	1991.00
IUUC-Laf-053761	Loxodonta africana	89.84	0.00e+00	2586.00
IUUC-Mcc-055505	Macaca mulatta	89.08	0.00e+00	2642.00
IUUC-Mga-059358	Meleagris gallopavo	79.22	0.00e+00	2347.00
IUUC-Mmr-060863	Microcebus murinus	90.77	0.00e+00	2619.00
IUUC-Mdo-061957	Monodelphis domestica	84.71	0.00e+00	2511.00
IUUC-Mmu-063944	Mus musculus	89.02	0.00e+00	2583.00
IUUC-Mac-065069	Musa acuminata	36.04	2.00e-08	55.80
IUUC-Mpu-066719	Mustela putorius furo	88.62	0.00e+00	2605.00
IUUC-Mlu-068086	Myotis lucifugus	86.66	0.00e+00	2504.00
IUUC-Nle-069256	Nomascus leucogenys	89.26	0.00e+00	2648.00
IUUC-Ont-071756	Oreochromis niloticus	61.06	0.00e+00	1781.00
IUUC-Oan-073568	Ornithorhynchus anatinus	86.88	0.00e+00	2527.00
IUUC-Ocu-073961	Oryctolagus cuniculus	89.42	0.00e+00	2593.00
IUUC-Ogl-077886	Oryza glaberrima	38.83	2.00e-16	81.60
IUUC-Olo-080668	Oryza longistaminata	38.83	4.00e-16	81.30
IUUC-Opu-083164	Oryza punctata	31.63	3.00e-88	321.00
IUUC-Osa-085487	Oryza sativa	38.83	1.00e-16	82.00
IUUC-Ola-086448	Oryzias latipes	60.64	0.00e+00	1746.00
IUUC-Oga-088501	Otolemur garnettii	86.97	0.00e+00	2250.00
IUUC-Ptr-090816	Pan troglodytes	89.14	0.00e+00	2650.00
IUUC-Pan-092764	Papio anubis	91.24	0.00e+00	2635.00
IUUC-Psi-093918	Pelodiscus sinensis	79.42	0.00e+00	2144.00
IUUC-Pfo-096672	Poecilia formosa	60.21	0.00e+00	1716.00
IUUC-Pab-097854	Pongo abelii	89.95	0.00e+00	2057.00
IUUC-Pca-100241	Procavia capensis	84.38	0.00e+00	1675.00
IUUC-Pva-103035	Pteropus vampyrus	84.29	0.00e+00	2182.00
IUUC-Rno-105574	Rattus norvegicus	87.62	0.00e+00	2526.00
IUUC-Sce-106207	Saccharomyces cerevisiae	35.59	3.00e-73	269.00
IUUC-Sly-111298	Solanum lycopersicum	42.21	1.00e-101	365.00
IUUC-Sar-113477	Sorex araneus	88.32	0.00e+00	2367.00
IUUC-Ssc-116132	Sus scrofa	94.06	0.00e+00	2349.00
IUUC-Tgu-117452	Taeniopygia guttata	80.72	0.00e+00	2326.00
IUUC-Tru-117561	Takifugu rubripes	58.38	0.00e+00	1695.00
IUUC-Tsy-119271	Tarsius syrichta	89.03	0.00e+00	2054.00
IUUC-Tni-119650	Tetraodon nigroviridis	64.13	0.00e+00	1659.00
IUUC-Tur-126632	Triticum urartu	32.65	1.00e-98	355.00
IUUC-Tbe-127890	Tupaia belangeri	83.90	0.00e+00	1427.00
IUUC-Ttr-128546	Tursiops truncatus	90.74	0.00e+00	1955.00
IUUC-Vpa-130432	Vicugna pacos	90.01	0.00e+00	1567.00
IUUC-Xtr-132008	Xenopus tropicalis	70.43	0.00e+00	2055.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence