iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000011862.1	ENSONIT00000014944.1	ENSONIP00000014932.1
ENSONIG00000011862.1	ENSONIT00000014945.1	ENSONIP00000014933.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.50e-97	326.5	39	390

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgy 87
           +Gl N+gNtCY+NSvLQ+L++++++re +l     k++    + +k++ll++l++lf+++   k+k +++ p+++++ l+ke+e f++y
   Q: 39   FGLVNFGNTCYCNSVLQALYFCRPFREKVLA---YKVQ----PRRKESLLTCLADLFNSIAtqKKKVGVIPPKKFISRLRKENELFDNY 120
           6******************************...4554....45789*************976777779******************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde........................aeekkkkknkslisdlFqgqlks 152
           +qqDa+Efl++ll+++ + l++    +k++e+ +++ +l ++                        + e  k+ ++++++++Fqg+l++
   Q: 121  MQQDAHEFLNYLLNTIADLLQE----EKSQER-QQNGKLVQNggggvgggggvggggsegggggggEGEGGKETQQTWVHEIFQGTLTN 204
           ********************33....222222.22223333378999******************99999999999************* PP
   S: 153  qikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfse 241
           +++cl+c+ vss++e+fldls++v++++     s+++cL+ f+++e+l++e kyyce+c++kqea+k++++kklP +L lhLkRf++  
   Q: 205  ETRCLNCEAVSSKDEDFLDLSVDVEQNT-----SITHCLRGFSNTETLCSEYKYYCEQCRSKQEAQKRMRVKKLPMILALHLKRFKYMD 288
           ****************************.....9******************************************************* PP
   S: 242  eqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetg.. 327
           + ++ +k++ +v fpleL l  f+ts +   + ++ Y+L+avvvH G +++ GHY+++vk+ +g WllfdD+ V++++ + ++e+ g  
   Q: 289  QLHRYTKLSYRVVFPLELRL--FNTSGDA-TNPDRLYDLVAVVVHCGsGPNRGHYITIVKS-HGFWLLFDDDIVEKIDAQAIEEFYGlt 373
           ***************66665..7777444.4469***************************.888*******************999** PP
   S: 328  .......staYvlfYkr 337
                  +++Y+lfY++
   Q: 374  sdisknsESGYILFYQS 390
           ***************97 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MEILMTVRKI ASICTMGANA SALEKEIGPE QFPVNEHYFG LVNFGNTCYC NSVLQALYFC 60
RPFREKVLAY KVQPRRKESL LTCLADLFNS IATQKKKVGV IPPKKFISRL RKENELFDNY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAAATAC TGATGACAGT CCGAAAGATT GCCTCGATTT GTACGATGGT AAGAAGCCGA 60
ATTCGGTGCT TTTATCCGCG GGGCGTGAAT GCGCTGCGCC TCTGTCCGGT CCCCCCTCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003733	Anas platyrhynchos	84.95	0.00e+00	661.00
IUUC-Aca-005054	Anolis carolinensis	87.50	0.00e+00	683.00
IUUC-Ame-011132	Astyanax mexicanus	94.64	0.00e+00	738.00
IUUC-Dre-027548	Danio rerio	93.62	0.00e+00	739.00
IUUC-Fal-037172	Ficedula albicollis	86.48	0.00e+00	674.00
IUUC-Gga-041044	Gallus gallus	87.50	0.00e+00	686.00
IUUC-Lch-050237	Latimeria chalumnae	86.99	0.00e+00	681.00
IUUC-Loc-052559	Lepisosteus oculatus	89.54	0.00e+00	715.00
IUUC-Mga-059602	Meleagris gallopavo	87.63	0.00e+00	661.00
IUUC-Psi-093379	Pelodiscus sinensis	88.01	0.00e+00	687.00
IUUC-Pfo-097041	Poecilia formosa	92.29	0.00e+00	714.00
IUUC-Tgu-116825	Taeniopygia guttata	86.73	0.00e+00	679.00
IUUC-Tru-118379	Takifugu rubripes	94.39	0.00e+00	744.00
IUUC-Xtr-132082	Xenopus tropicalis	88.52	0.00e+00	706.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence