iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-010616

Ensembl Protein ID

ENSAMXP00000005923.1

UniProt Accession

W5KEB2; W5KEB2_ASTMX

Genbank Protein ID

ENSAMXP00000005923

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01100515

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000005773.1	ENSAMXT00000005923.1	ENSAMXP00000005923.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.20e-78	263.5	445	933

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           tGl NlgNtCYmNS++Q+L++ +++r+ +l+    +ln +      ++l+k+lq lf+ l ++++ a++pr++l+a +   + f+  +q
   Q: 445  TGLVNLGNTCYMNSIIQTLFMATDFRRSVLS---LHLNGS------NTLMKKLQLLFAFLAHTQRAAYAPRNFLEASR--PPWFTVGSQ 522
           7******************************...666665......59***************************998..777****** PP
   S: 90   qDaqEflaflldqleeelkk....eknkpkeeeeeedkselsde..................aeekkkkknkslisdlFqgqlksqikc 156
           qD++E+l+flld+l+ee k     +++kpk++++++d      +                  ++e+ k ++++l++++F+g+l++ i+c
   Q: 523  QDCSEYLRFLLDRLHEEEKTlralQTTKPKTDSSDAD------IidegashrvpnslpsshpEPEDAKGEGQTLVERMFGGRLSTGIRC 605
           ******************6665555555555554444......134466699*******9999999999999***************** PP
   S: 157  lecdnvssreepfldlslpvpgkeetkke.................................slqdcLesftkeeelegenkyycekck 212
           l+c++ s++eepf+dlsl++     +++                                  sl+d+ e f ++e le+en y+ce+c 
   Q: 606  LQCHSLSEKEEPFTDLSLAFCPPALQSTVgpcqgsvnggsenlegpvkepqsverptsepalSLTDLVEYFLAPEILEEENCYFCERCG 694
           ********************99887666699********************************************************** PP
   S: 213  kkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple..Ldlspfcts................................ 267
           ++q+ae+ +++   Pe+Lil L Rfs++ + ++r+ki ++v +pl+  L + ++ +s                                
   Q: 695  SLQRAERAMRVVAAPEYLILTLLRFSYDATCHVRRKILDNVRIPLRmcLPVHQHHASasntgaatvalssssssssplapmdspesgen 783
           ********************************************994444445444466666666666666666666666666666666 PP
   S: 268  ..........peekqke...........................kkkYeLiavvvHsG.slssGHYvayvkn................. 301
                     +     e                           ++ Y L++vv+HsG s++sGHY++y +n                 
   Q: 784  lakklkpsrrE-----EeeeeeqekgltdsgregglrgersdmhSVPYVLSSVVMHSGmSSESGHYYSYGRNvsgtdrlanpccrtset 867
           66555555550.....0555556678888888888888888888********************************************* PP
   S: 302  .........................ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
                                    ++++W+lf+Ds+Vt ++ ++v++ t+    +taYvl+Y+++
   Q: 868  daglsnssqsescaaprevlesagqNSRDWFLFNDSRVTFTNFQSVQNITSrfpkDTAYVLIYRKQ 933
           **********9999999999988766666*******************999************986 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MDKILEALVS SSHPLPIKRA IVKKVVEAAE KEVTQEQCQA LYQLSTRLIL QGEDAFQRQV 60
GQQVQEAYAR FHRDEFARFL SKEFVLGLLQ QGYGTLDRRD PAILDFLHGS LRLLLSCPAV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTTTGTTAA CGGCGCTCTG TAGGACAGAG GCAGGGTCCT GGCGTGACGT TTGCGTCATC 60
AGCTGACTGC CGGAGCGACG GGAGTGAAAA CAGATCATCA GAAAAACGGA AAAGTGCGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002174	Ailuropoda melanoleuca	61.40	0.00e+00	1169.00
IUUC-Apl-003435	Anas platyrhynchos	61.58	0.00e+00	979.00
IUUC-Aca-004556	Anolis carolinensis	58.46	0.00e+00	1090.00
IUUC-Bta-013544	Bos taurus	62.27	0.00e+00	1170.00
IUUC-Cja-018745	Callithrix jacchus	61.09	0.00e+00	1196.00
IUUC-Cfa-020434	Canis familiaris	61.45	0.00e+00	1147.00
IUUC-Cpo-021666	Cavia porcellus	61.77	0.00e+00	1143.00
IUUC-Csa-023965	Chlorocebus sabaeus	62.43	0.00e+00	1229.00
IUUC-Cho-024809	Choloepus hoffmanni	54.06	0.00e+00	756.00
IUUC-Cin-025604	Ciona intestinalis	31.97	2.00e-43	169.00
IUUC-Csv-026333	Ciona savignyi	41.44	2.00e-31	129.00
IUUC-Dre-028338	Danio rerio	76.78	0.00e+00	1564.00
IUUC-Dno-029372	Dasypus novemcinctus	62.18	0.00e+00	1207.00
IUUC-Dor-030752	Dipodomys ordii	57.23	0.00e+00	736.00
IUUC-Dme-031871	Drosophila melanogaster	29.48	3.00e-63	236.00
IUUC-Ete-032588	Echinops telfairi	53.37	0.00e+00	697.00
IUUC-Eca-034416	Equus caballus	62.33	0.00e+00	1226.00
IUUC-Eeu-035132	Erinaceus europaeus	50.05	0.00e+00	870.00
IUUC-Fca-036137	Felis catus	61.87	0.00e+00	1219.00
IUUC-Fal-037297	Ficedula albicollis	61.00	0.00e+00	1153.00
IUUC-Gmo-038727	Gadus morhua	74.84	0.00e+00	1120.00
IUUC-Gga-041091	Gallus gallus	61.09	0.00e+00	1117.00
IUUC-Gac-042082	Gasterosteus aculeatus	70.58	0.00e+00	1278.00
IUUC-Ggo-045376	Gorilla gorilla	58.65	0.00e+00	1109.00
IUUC-Hsa-046444	Homo sapiens	62.62	0.00e+00	1232.00
IUUC-Itr-047976	Ictidomys tridecemlineatus	62.03	0.00e+00	1223.00
IUUC-Lch-050500	Latimeria chalumnae	61.05	0.00e+00	1219.00
IUUC-Loc-052625	Lepisosteus oculatus	67.22	0.00e+00	1374.00
IUUC-Laf-053689	Loxodonta africana	61.65	0.00e+00	1208.00
IUUC-Mcc-055286	Macaca mulatta	62.30	0.00e+00	1222.00
IUUC-Meu-056906	Macropus eugenii	49.68	0.00e+00	632.00
IUUC-Mga-059905	Meleagris gallopavo	60.23	0.00e+00	962.00
IUUC-Mmr-061397	Microcebus murinus	62.50	0.00e+00	1183.00
IUUC-Mdo-062833	Monodelphis domestica	62.25	0.00e+00	1265.00
IUUC-Mmu-063157	Mus musculus	61.69	0.00e+00	1176.00
IUUC-Mpu-066434	Mustela putorius furo	62.64	0.00e+00	1229.00
IUUC-Mlu-068178	Myotis lucifugus	62.22	0.00e+00	1156.00
IUUC-Nle-070153	Nomascus leucogenys	62.43	0.00e+00	1166.00
IUUC-Opr-070454	Ochotona princeps	46.00	5.00e-69	256.00
IUUC-Ont-072330	Oreochromis niloticus	68.84	0.00e+00	1363.00
IUUC-Oan-072709	Ornithorhynchus anatinus	61.01	0.00e+00	946.00
IUUC-Ocu-074832	Oryctolagus cuniculus	62.49	0.00e+00	1193.00
IUUC-Ola-087003	Oryzias latipes	61.00	8.00e-58	216.00
IUUC-Oga-088517	Otolemur garnettii	61.72	0.00e+00	1023.00
IUUC-Oar-089472	Ovis aries	59.67	0.00e+00	1091.00
IUUC-Ptr-090996	Pan troglodytes	62.62	0.00e+00	1234.00
IUUC-Pan-091837	Papio anubis	60.93	0.00e+00	1183.00
IUUC-Psi-093236	Pelodiscus sinensis	62.14	0.00e+00	897.00
IUUC-Pma-094349	Petromyzon marinus	52.29	0.00e+00	945.00
IUUC-Pfo-097193	Poecilia formosa	68.62	0.00e+00	1291.00
IUUC-Pab-098710	Pongo abelii	62.49	0.00e+00	1252.00
IUUC-Pca-100794	Procavia capensis	55.12	0.00e+00	1024.00
IUUC-Pva-102722	Pteropus vampyrus	62.28	0.00e+00	1219.00
IUUC-Rno-105743	Rattus norvegicus	61.42	0.00e+00	1170.00
IUUC-Sha-106563	Sarcophilus harrisii	61.94	0.00e+00	1022.00
IUUC-Sar-113533	Sorex araneus	56.35	0.00e+00	1026.00
IUUC-Ssc-116259	Sus scrofa	76.45	0.00e+00	796.00
IUUC-Tgu-117475	Taeniopygia guttata	59.98	0.00e+00	1035.00
IUUC-Tru-118623	Takifugu rubripes	66.29	0.00e+00	1256.00
IUUC-Tsy-119250	Tarsius syrichta	60.75	0.00e+00	901.00
IUUC-Tni-120441	Tetraodon nigroviridis	62.74	0.00e+00	1179.00
IUUC-Tbe-127936	Tupaia belangeri	52.25	0.00e+00	895.00
IUUC-Ttr-128483	Tursiops truncatus	51.22	0.00e+00	806.00
IUUC-Vpa-130303	Vicugna pacos	77.34	0.00e+00	855.00
IUUC-Xtr-132773	Xenopus tropicalis	60.44	0.00e+00	1163.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence